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The Experts below are selected from a list of 327 Experts worldwide ranked by ideXlab platform

Rabia Nazir - One of the best experts on this subject based on the ideXlab platform.

  • Collagen–hyaluronic acid based interpenetrating polymer networks as tissue engineered heart valve
    Materials Science and Technology, 2016
    Co-Authors: Rabia Nazir
    Abstract:

    Currently, custom made heart implants suffer from critical imperfections in terms of mechanical incompatibility and uncontrolled degradation rate, which leads to premature in vivo failure. Interpenetrating polymer networks (IPNs) are a success story in drug delivery and regenerative medicine where they offer fascinating morphologies and tailored properties like controlled degradation rate. This review will critically discuss the current state of the art with respect to the two most important biopolymers found in heart valve, i.e. collagen and hyaluronic acid formulated IPNs as tissue engineered heart valve (TEHV). Comparison of the existing experimental approaches and recent technical challenges will be demonstrated. Finally, multifaceted proposals for improvements in design and performance of TEHVs will be presented as a Route Map for future research.

  • collagen hyaluronic acid based interpenetrating polymer networks as tissue engineered heart valve
    Materials Science and Technology, 2016
    Co-Authors: Rabia Nazir
    Abstract:

    Currently, custom made heart implants suffer from critical imperfections in terms of mechanical incompatibility and uncontrolled degradation rate, which leads to premature in vivo failure. Interpenetrating polymer networks (IPNs) are a success story in drug delivery and regenerative medicine where they offer fascinating morphologies and tailored properties like controlled degradation rate. This review will critically discuss the current state of the art with respect to the two most important biopolymers found in heart valve, i.e. collagen and hyaluronic acid formulated IPNs as tissue engineered heart valve (TEHV). Comparison of the existing experimental approaches and recent technical challenges will be demonstrated. Finally, multifaceted proposals for improvements in design and performance of TEHVs will be presented as a Route Map for future research.

Zhuang Wei - One of the best experts on this subject based on the ideXlab platform.

Tetsuya Taketsugu - One of the best experts on this subject based on the ideXlab platform.

  • Visualization of the Intrinsic Reaction Coordinate and Global Reaction Route Map by Classical Multidimensional Scaling.
    Journal of chemical theory and computation, 2018
    Co-Authors: Takuro Tsutsumi, Yuriko Ono, Zin Arai, Tetsuya Taketsugu
    Abstract:

    A classical multidimensional scaling (CMDS) method is employed to visualize an intrinsic reaction coordinate (IRC) and a global reaction Route Map consisting of the equilibrium minima and transition state structures connected by the IRC network. As demonstrations, the method was applied to the IRCs of the intramolecular proton transfer in malonaldehyde and the SN2 reaction of OH– + CH3F → CH3OH + F–, which are both well described by two principal coordinates. Next, the method was applied to the global reaction Route Map of the Au5 cluster; the resulting Map shows appropriate positions of five minima and 14 transition states in a reduced 2- or 3-dimensional coordinate space successfully.

  • Analyses of trajectory on-the-fly based on the global reaction Route Map
    Physical chemistry chemical physics : PCCP, 2018
    Co-Authors: Takuro Tsutsumi, Yuriko Ono, Yu Harabuchi, Satoshi Maeda, Tetsuya Taketsugu
    Abstract:

    A methodology to analyze a trajectory on-the-fly (TOF) based on a global reaction Route Map consisting of intrinsic reaction coordinate (IRC) pathways is proposed. By using the distance functions in the configurational space, the location of each point on the trajectories is detected, providing a dynamical picture that the molecular system goes over several minima and transition states in the reaction path network. In its application to structural transformations of an Au5 cluster, a variety of reaction Routes are obtained, and the hopping from one IRC to another IRC (IRC-jump) is analyzed. The branching of trajectories over many minima on the potential energy surface via valley-ridge transition points is also discussed.

  • Analyses of bifurcation of reaction pathways on a global reaction Route Map: a case study of gold cluster Au5.
    The Journal of chemical physics, 2015
    Co-Authors: Yu Harabuchi, Yuriko Ono, Satoshi Maeda, Tetsuya Taketsugu
    Abstract:

    A global reaction Route Map is generated for Au5 by the anharmonic downward distortion following method in which 5 minima and 14 transition states (TSs) are located. Through vibrational analyses in the 3N − 7 (N = 5) dimensional space orthogonal to the intrinsic reaction coordinate (IRC), along all the IRCs, four IRCs are found to have valley-ridge transition (VRT) points on the way where a potential curvature changes its sign from positive to negative in a direction orthogonal to the IRC. The detailed mechanisms of bifurcations related to the VRTs are discussed by surveying a landscape of the global reaction Route Map, and the connectivity of VRT points and minima is clarified. Branching of the products through bifurcations is confirmed by ab initio molecular dynamics simulations starting from the TSs. A new feature of the reaction pathways, unification, is found and discussed.

Jian Zuo - One of the best experts on this subject based on the ideXlab platform.

  • Strategic Route Map of sulphur dioxide reduction in China
    Energy Policy, 2013
    Co-Authors: Xueliang Yuan, Jian Zuo
    Abstract:

    China's economy has risen to the second place since 2010, accompanied by the largest energy consumption in the world. As one of the major air pollutants from the fossil fuel, excessive SO2 emissions have severe negative impacts on eco-environments. In order to achieve the balance between economic growth and environmental protection, many efforts have been made on the reduction of SO2. The Route Map for the reduction of SO2 in China includes policy setting, economic and energy structure adjustment, and the construction of desulphurization facilities. These initiatives and efforts together had resulted in the significant reduction of SO2 emissions along with fast economic development. This study provides a useful reference for other developing countries in coping SO2 control. The findings also provide implications for reducing the other two air pollutants with binding control targets in the Twelfth Five-Year Plan period in China, i.e. NOx and CO2.

Marjorie Skubic - One of the best experts on this subject based on the ideXlab platform.

  • Qualitative analysis of sketched Route Maps: translating a sketch into linguistic descriptions
    IEEE transactions on systems man and cybernetics. Part B Cybernetics : a publication of the IEEE Systems Man and Cybernetics Society, 2004
    Co-Authors: Marjorie Skubic, Samuel Blisard, C. Bailey, Julie A. Adams, Pascal Matsakis
    Abstract:

    In this correspondence, we introduce our work on sketch understanding, focusing here on the analysis of a sketched Route Map. A Route Map is drawn to help someone navigate along a path for the purpose of reaching a goal. A hand-sketched Route Map does not generally contain complete Map information and is not necessarily drawn to scale, but yet it contains the correct qualitative information for Route navigation. Here we propose a methodology for extracting a qualitative model of a sketched Route Map, based on human navigation strategies, using spatial relationships. Linguistic descriptions are generated from the sketch, both in the form of detailed descriptions at discrete path steps and also as a high-level Route description. To describe the path linguistically, one must first be able to understand the path in a qualitative sense. We assert that the translation of a sketch into linguistic descriptions illustrates that the essential qualitative path knowledge has been extracted. The methodology is demonstrated using example sketches drawn on a handheld PDA.

  • ICRA - Robot navigation using qualitative landmark states from sketched Route Maps
    IEEE International Conference on Robotics and Automation 2004. Proceedings. ICRA '04. 2004, 2004
    Co-Authors: G. Chronis, Marjorie Skubic
    Abstract:

    The goal of this work is to illustrate and evaluate a novel method for communicating with a mobile robot, namely, by drawing a sketch. The user draws a sketched Route Map to direct a mobile robot along a specified path. In this paper we focus on the navigation of the sketched path in the real environment. Challenges include sketch inaccuracies such as distortion or abstraction and low sensory resolution of the robot. Our method is based on utilizing spatial relations to extract a sequence of qualitative landmark states from the sketched Map, which in turn the robot follows in a real environment to replicate the sketched Route. Several examples are included.