Santalum Album

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Senhua Chen - One of the best experts on this subject based on the ideXlab platform.

  • a new β tetralonyl glucoside from the Santalum Album derived endophytic fungus colletotrichum sp gdmu 1
    Natural Product Research, 2019
    Co-Authors: Senhua Chen, Jing Li, Xuemei Yang
    Abstract:

    A new β-tetralonyl glucoside, methylberchemiaside (1), along with five known compounds (2–6) were isolated from a fungus Colletotrichum sp. GDMU-1 derived from the leaves of Santalum Album....

  • a new β tetralonyl glucoside from the Santalum Album derived endophytic fungus colletotrichum sp gdmu 1
    Natural Product Research, 2019
    Co-Authors: Weiyang Liu, Senhua Chen, Xuemei Yang, Chong Yan, Hongju Liu
    Abstract:

    A new β-tetralonyl glucoside, methylberchemiaside (1), along with five known compounds (2–6) were isolated from a fungus Colletotrichum sp. GDMU-1 derived from the leaves of Santalum Album. Their s...

  • bioactive terpenoids from Santalum Album derived endophytic fungus fusarium sp yd 2
    RSC Advances, 2018
    Co-Authors: Jing Li, Yanlian Deng, Senhua Chen
    Abstract:

    Two new spiromeroterpenoids, namely fusariumin A (1) and B (2), along with four known terpenoids, asperterpenoid A (3), agathic acid (4), guignardone N (5), and trametenolic acid (6), were obtained from the endophytic fungus Fusarium sp. YD-2, derived from the twigs of Santalum Album. Their structures were elucidated by a combination of spectroscopic analyses. The absolute configuration of 1 was determined by single-crystal X-ray diffraction using Cu Kα radiation, and that of 2 was elucidated on the basis of experimental and calculated electronic circular dichroism spectra. Compound 2 exhibited moderate anti-inflammatory activity in vitro by inhibiting nitric oxide (NO) production in lipopolysaccharide activated RAW264.7 cells with an IC50 value of 50 μM, and compound 3 showed strong anti-inflammatory activity with an IC50 value of 1.6 μM. In the antibacterial assay, compound 1 displayed significant activities against Staphylococcus aureus and Pseudomonas aeruginosa with an MIC value of 6.3 μg mL−1, and compound 3 showed moderate activities against Salmonella enteritidis and Micrococcus luteus with MIC values of 6.3 and 25.2 μg mL−1, respectively.

  • A new β-tetralonyl glucoside from the Santalum Album derived endophytic fungus Colletotrichum sp. GDMU-1
    2018
    Co-Authors: Weiyang Liu, Senhua Chen, Xuemei Yang, Chong Yan, Hongju Liu
    Abstract:

    A new β-tetralonyl glucoside, methylberchemiaside (1), along with five known compounds (2–6) were isolated from a fungus Colletotrichum sp. GDMU-1 derived from the leaves of Santalum Album. Their structures were determined by detailed analysis of spectroscopic data. All compounds were tested for the inhibitory effects on the nitric oxide (NO) production in lipopolysaccharide (LPS)-treated RAW264.7 cells. Among them, compounds 4 and 5 showed moderate anti-inflammatory activity with IC50 value of 30.4 and 8.9 μM, respectively.

Xuemei Yang - One of the best experts on this subject based on the ideXlab platform.

Hongju Liu - One of the best experts on this subject based on the ideXlab platform.

Jing Li - One of the best experts on this subject based on the ideXlab platform.

  • a new β tetralonyl glucoside from the Santalum Album derived endophytic fungus colletotrichum sp gdmu 1
    Natural Product Research, 2019
    Co-Authors: Senhua Chen, Jing Li, Xuemei Yang
    Abstract:

    A new β-tetralonyl glucoside, methylberchemiaside (1), along with five known compounds (2–6) were isolated from a fungus Colletotrichum sp. GDMU-1 derived from the leaves of Santalum Album....

  • bioactive terpenoids from Santalum Album derived endophytic fungus fusarium sp yd 2
    RSC Advances, 2018
    Co-Authors: Jing Li, Yanlian Deng, Senhua Chen
    Abstract:

    Two new spiromeroterpenoids, namely fusariumin A (1) and B (2), along with four known terpenoids, asperterpenoid A (3), agathic acid (4), guignardone N (5), and trametenolic acid (6), were obtained from the endophytic fungus Fusarium sp. YD-2, derived from the twigs of Santalum Album. Their structures were elucidated by a combination of spectroscopic analyses. The absolute configuration of 1 was determined by single-crystal X-ray diffraction using Cu Kα radiation, and that of 2 was elucidated on the basis of experimental and calculated electronic circular dichroism spectra. Compound 2 exhibited moderate anti-inflammatory activity in vitro by inhibiting nitric oxide (NO) production in lipopolysaccharide activated RAW264.7 cells with an IC50 value of 50 μM, and compound 3 showed strong anti-inflammatory activity with an IC50 value of 1.6 μM. In the antibacterial assay, compound 1 displayed significant activities against Staphylococcus aureus and Pseudomonas aeruginosa with an MIC value of 6.3 μg mL−1, and compound 3 showed moderate activities against Salmonella enteritidis and Micrococcus luteus with MIC values of 6.3 and 25.2 μg mL−1, respectively.

Weiyang Liu - One of the best experts on this subject based on the ideXlab platform.