The Experts below are selected from a list of 1308 Experts worldwide ranked by ideXlab platform
Fikrettin şahin - One of the best experts on this subject based on the ideXlab platform.
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control of aspergillus flavus with essential oil and methanol extract of Satureja Hortensis
International Journal of Food Microbiology, 2008Co-Authors: Neslihan Dikbas, Recep Kotan, Fatih Dadasoglu, Fikrettin şahinAbstract:Abstract The essential oil and methanol extract of Satureja Hortensis were tested for antifungal activity against Aspergillus flavus in vitro on Petri plates and liquid culture, and under storage conditions. The oil showed strong antifungal activity based on the inhibition zone and minimal inhibitory concentration values against the pathogen on Petri plates assays. The very low concentrations of them also reduced wet and dry mycelium weight of pathogen fungus in liquid culture. When the oils at 25, 12.5 and 6.25 µl/mL concentrations were applied to lemon fruits before seven days of pathogen inoculation on storage conditions, the decay on fruits caused by the pathogen could be prevent completely. The results in this study showed that the essential oil of S. Hortensis had strong antifungal activity against pathogen fungi tested. So, the essential oil of S. Hortensis could be used for management of this pathogen as a potential source of sustainable eco-friendly botanical fungicides.
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effects of aqueous extracts of Satureja Hortensis l on rhinosinusitis treatment in rabbit
Journal of Ethnopharmacology, 2003Co-Authors: Celil Uslu, Fikrettin şahin, Murat R Karasen, Seyithan Taysi, Fatih AkcayAbstract:Abstract Satureja Hortensis L. (Lamiaceae) is an annual herb that used as traditional folk medicine in Eastern Anatolia region of Turkey for treatment of different infectious diseases and disorders. This study was designated to investigate anti-inflammatory effect of aqueous extract (250 mg/kg) of Satureja Hortensis. Therapeutic potential of Satureja Hortensis as an anti-inflammatory agent was examined by measurement of NO metabolites and histological changes in a rabbit model of rhinosinusitis. The results showed that both activity of NOS enzyme and concentration of NO metabolites were significantly reduced by topical administration of Satureja Hortensis extract. Histological examination demonstrated no edema and/or reduced inflammation in therapy group as compared to the control. Thus, the data suggest Satureja Hortensis extract may have the potential to be used as anti-inflammation agent, and can be used in the treatment of rhinosinusitis diseases.
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evaluation of antimicrobial activities of Satureja Hortensis l
Journal of Ethnopharmacology, 2003Co-Authors: Fikrettin şahin, Isa Karaman, Medine Gulluce, Hatice Ogutcu, Meryem şengul, Ahmet Adiguzel, S Ozturk, Recep KotanAbstract:The present study was designated to evaluate the antimicrobial activities of methonol and hexane extracts of Satureja Hortensis L. which is an annual herb used as traditional folk medicine in Eastern Anatolia region of Turkey for the treatment of different infectious diseases and disorders. The antimicrobial activities of the extracts against 147 laboratory strains belong to 55 bacterial species, and 31 isolates of 1 yeast and 4 fungi species were tested by using disc diffusion assay. The results showed that hexane extract of Satureja Hortensis had no antifungal, but antibacterial activity against four strains of three Bacillus species whereas methanol extract of Satureja Hortensis had both anticandidal and antibacterial effects. It inhibited the growth of 23 strains of 11 bacterial species and 6 isolates of Candida albicans, at the concentration of 300 μg/ml. Satureja Hortensis did not show antimicrobial activity against the remaining microorganisms (83%) tested including most and all of the clinic and plant pathogenic microorganisms, respectively. Methanol extract showed stronger and broader spectrum of antimicrobial activity as compared to hexane extract.
Sediqa Amery - One of the best experts on this subject based on the ideXlab platform.
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Relaxant effect of Satureja Hortensis on guinea pig tracheal chains and its possible mechanism(s)
DARU, 2020Co-Authors: Mohammad Hossein Boskabady, Mohammad Reza Aslani, F Mansuri, Sediqa AmeryAbstract:Background: In Iranian ancient medical books, the therapeutic effects of Satureja Hortensis on respiratory diseases have been reported. In order to verify these reports, the relaxant effect of aqueous-ethanolic extract of Satureja Hortensis on guinea pig trachea was examined. Methods: The relaxant effects of 6 cumulative concentrations of extract (0.15, 0.3, 0.45, 0.6, 0.75 and 0.9 g %) in comparison with saline and 4 cumulative concentrations of theophylline (0.15, 0.3, 0.45, and 0.6 mM) by their effects on precontracted tracheal chains of guinea pig by 10 µM methacholine (group 1) or 60 mM KCl in two different conditions including: non-incubated tissues (group 2) and incubated tissues with 1 µM propranolol, 1 µM chlorpheniramine and 1 µM atropine (group 3, for each group n=6) were examined. Results: In group 1, the extract and theophylline showed concentration dependent relaxant effects compared to that of saline (p
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relaxant effect of Satureja Hortensis on guinea pig tracheal chains and its possible mechanism s
DARU, 2007Co-Authors: Mohammad Hossein Boskabady, Mohammad Reza Aslani, F Mansuri, Sediqa AmeryAbstract:Background: In Iranian ancient medical books, the therapeutic effects of Satureja Hortensis on respiratory diseases have been reported. In order to verify these reports, the relaxant effect of aqueous-ethanolic extract of Satureja Hortensis on guinea pig trachea was examined. Methods: The relaxant effects of 6 cumulative concentrations of extract (0.15, 0.3, 0.45, 0.6, 0.75 and 0.9 g %) in comparison with saline and 4 cumulative concentrations of theophylline (0.15, 0.3, 0.45, and 0.6 mM) by their effects on precontracted tracheal chains of guinea pig by 10 µM methacholine (group 1) or 60 mM KCl in two different conditions including: non-incubated tissues (group 2) and incubated tissues with 1 µM propranolol, 1 µM chlorpheniramine and 1 µM atropine (group 3, for each group n=6) were examined. Results: In group 1, the extract and theophylline showed concentration dependent relaxant effects compared to that of saline (p<0.05 to p<0.001). In group 2, three last concentrations of theophylline and four higher concentrations of extract showed significant relaxant effects compared to that of saline (p<0.05 to p<0.001). The effects of four lower concentrations of extracts in groups 1 and 2 were significantly lower than those of theophylline (p<0.05 p<0.001). In group 3, the extract did not show any significant relaxant effect. There were significant correlations between the relaxant effects and concentrations of extract and theophylline in groups 1 and 2 (p<0.001 for all cases). Conclusion: These results showed a potent relaxant effect of Satureja Hortensis on guinea pigs trachea which was comparable to that of theophylline.
Mostafa Khajeh - One of the best experts on this subject based on the ideXlab platform.
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optimization of process variables for essential oil components from Satureja Hortensis by supercritical fluid extraction using box behnken experimental design
Journal of Supercritical Fluids, 2011Co-Authors: Mostafa KhajehAbstract:Abstract The oil and extracts of Satureja Hortensis cultivated in Iran were extracted using supercritical carbon dioxide and hydrodistillation method. The oil and extracts were analyzed by GC-FID and GC/MS. The compounds were identified according to their retention indices and mass spectra (EI, 70 eV). The effects of various parameters such as pressure, temperature, percent of modifier (methanol) and extraction time, were investigated by a fractional factorial design (2 4-1 ) to determine the significant parameters and their interactions. The results showed that the pressure, temperature and percent of modifier are significant ( p
Mohammad Hossein Boskabady - One of the best experts on this subject based on the ideXlab platform.
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Relaxant effect of Satureja Hortensis on guinea pig tracheal chains and its possible mechanism(s)
DARU, 2020Co-Authors: Mohammad Hossein Boskabady, Mohammad Reza Aslani, F Mansuri, Sediqa AmeryAbstract:Background: In Iranian ancient medical books, the therapeutic effects of Satureja Hortensis on respiratory diseases have been reported. In order to verify these reports, the relaxant effect of aqueous-ethanolic extract of Satureja Hortensis on guinea pig trachea was examined. Methods: The relaxant effects of 6 cumulative concentrations of extract (0.15, 0.3, 0.45, 0.6, 0.75 and 0.9 g %) in comparison with saline and 4 cumulative concentrations of theophylline (0.15, 0.3, 0.45, and 0.6 mM) by their effects on precontracted tracheal chains of guinea pig by 10 µM methacholine (group 1) or 60 mM KCl in two different conditions including: non-incubated tissues (group 2) and incubated tissues with 1 µM propranolol, 1 µM chlorpheniramine and 1 µM atropine (group 3, for each group n=6) were examined. Results: In group 1, the extract and theophylline showed concentration dependent relaxant effects compared to that of saline (p
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relaxant effect of Satureja Hortensis on guinea pig tracheal chains and its possible mechanism s
DARU, 2007Co-Authors: Mohammad Hossein Boskabady, Mohammad Reza Aslani, F Mansuri, Sediqa AmeryAbstract:Background: In Iranian ancient medical books, the therapeutic effects of Satureja Hortensis on respiratory diseases have been reported. In order to verify these reports, the relaxant effect of aqueous-ethanolic extract of Satureja Hortensis on guinea pig trachea was examined. Methods: The relaxant effects of 6 cumulative concentrations of extract (0.15, 0.3, 0.45, 0.6, 0.75 and 0.9 g %) in comparison with saline and 4 cumulative concentrations of theophylline (0.15, 0.3, 0.45, and 0.6 mM) by their effects on precontracted tracheal chains of guinea pig by 10 µM methacholine (group 1) or 60 mM KCl in two different conditions including: non-incubated tissues (group 2) and incubated tissues with 1 µM propranolol, 1 µM chlorpheniramine and 1 µM atropine (group 3, for each group n=6) were examined. Results: In group 1, the extract and theophylline showed concentration dependent relaxant effects compared to that of saline (p<0.05 to p<0.001). In group 2, three last concentrations of theophylline and four higher concentrations of extract showed significant relaxant effects compared to that of saline (p<0.05 to p<0.001). The effects of four lower concentrations of extracts in groups 1 and 2 were significantly lower than those of theophylline (p<0.05 p<0.001). In group 3, the extract did not show any significant relaxant effect. There were significant correlations between the relaxant effects and concentrations of extract and theophylline in groups 1 and 2 (p<0.001 for all cases). Conclusion: These results showed a potent relaxant effect of Satureja Hortensis on guinea pigs trachea which was comparable to that of theophylline.
Fatih Akcay - One of the best experts on this subject based on the ideXlab platform.
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effects of aqueous extracts of Satureja Hortensis l on rhinosinusitis treatment in rabbit
Journal of Ethnopharmacology, 2003Co-Authors: Celil Uslu, Fikrettin şahin, Murat R Karasen, Seyithan Taysi, Fatih AkcayAbstract:Abstract Satureja Hortensis L. (Lamiaceae) is an annual herb that used as traditional folk medicine in Eastern Anatolia region of Turkey for treatment of different infectious diseases and disorders. This study was designated to investigate anti-inflammatory effect of aqueous extract (250 mg/kg) of Satureja Hortensis. Therapeutic potential of Satureja Hortensis as an anti-inflammatory agent was examined by measurement of NO metabolites and histological changes in a rabbit model of rhinosinusitis. The results showed that both activity of NOS enzyme and concentration of NO metabolites were significantly reduced by topical administration of Satureja Hortensis extract. Histological examination demonstrated no edema and/or reduced inflammation in therapy group as compared to the control. Thus, the data suggest Satureja Hortensis extract may have the potential to be used as anti-inflammation agent, and can be used in the treatment of rhinosinusitis diseases.
