The Experts below are selected from a list of 306 Experts worldwide ranked by ideXlab platform
Gregory B. Dudley - One of the best experts on this subject based on the ideXlab platform.
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The Meyer–Schuster rearrangement for the synthesis of α,β-unsaturated carbonyl compounds
Organic & biomolecular chemistry, 2009Co-Authors: Douglas A. Engel, Gregory B. DudleyAbstract:The Meyer–Schuster rearrangement is the conversion of propargyl alcohols into α,β-unsaturated carbonyl compounds via a formal 1,3-hydroxyl shift and tautomerization. The major challenge associated with the Meyer–Schuster Reaction is that of selectively promoting the desired rearrangement over the myriad other Reaction pathways available to propargyl alcohols. This Perspective Article features recent advances in the Meyer–Schuster Reaction, including several demonstrated techniques for improving the scope. Strengths and weaknesses of each technique are discussed, and outstanding problems that warrant further study are highlighted. The primary motivation for research and development of the Meyer–Schuster rearrangement is as a means of preparing α,β-unsaturated carbonyl compounds as part of a two-stage olefination strategy.
Douglas A. Engel - One of the best experts on this subject based on the ideXlab platform.
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The Meyer–Schuster rearrangement for the synthesis of α,β-unsaturated carbonyl compounds
Organic & biomolecular chemistry, 2009Co-Authors: Douglas A. Engel, Gregory B. DudleyAbstract:The Meyer–Schuster rearrangement is the conversion of propargyl alcohols into α,β-unsaturated carbonyl compounds via a formal 1,3-hydroxyl shift and tautomerization. The major challenge associated with the Meyer–Schuster Reaction is that of selectively promoting the desired rearrangement over the myriad other Reaction pathways available to propargyl alcohols. This Perspective Article features recent advances in the Meyer–Schuster Reaction, including several demonstrated techniques for improving the scope. Strengths and weaknesses of each technique are discussed, and outstanding problems that warrant further study are highlighted. The primary motivation for research and development of the Meyer–Schuster rearrangement is as a means of preparing α,β-unsaturated carbonyl compounds as part of a two-stage olefination strategy.
Jianyu Dong - One of the best experts on this subject based on the ideXlab platform.
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Phosphorous acid promoted isomerization of propargyl alcohols to α,β-unsaturated carbonyl compounds
Tetrahedron Letters, 2019Co-Authors: Xiaotang Gan, Lixin Liu, Yani Yan, Chao Chen, Yongbo Zhou, Jianyu DongAbstract:Abstract A metal-free and two-phase protocol for the Meyer-Schuster isomerization of propargyl alcohols to the corresponding α,β-unsaturated carbonyl compounds has been achieved in the presence of stoichiometric phosphorous acid aqueous solution, which produces the desired products in high yields with excellent stereoselectivity. Compared with the traditional methods, the procedure features broad scope of the substrates, mild conditions, and easy separation, providing an appealing alternative to the Meyer-Schuster Reaction.
Xiaotang Gan - One of the best experts on this subject based on the ideXlab platform.
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Phosphorous acid promoted isomerization of propargyl alcohols to α,β-unsaturated carbonyl compounds
Tetrahedron Letters, 2019Co-Authors: Xiaotang Gan, Lixin Liu, Yani Yan, Chao Chen, Yongbo Zhou, Jianyu DongAbstract:Abstract A metal-free and two-phase protocol for the Meyer-Schuster isomerization of propargyl alcohols to the corresponding α,β-unsaturated carbonyl compounds has been achieved in the presence of stoichiometric phosphorous acid aqueous solution, which produces the desired products in high yields with excellent stereoselectivity. Compared with the traditional methods, the procedure features broad scope of the substrates, mild conditions, and easy separation, providing an appealing alternative to the Meyer-Schuster Reaction.
Lixin Liu - One of the best experts on this subject based on the ideXlab platform.
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Phosphorous acid promoted isomerization of propargyl alcohols to α,β-unsaturated carbonyl compounds
Tetrahedron Letters, 2019Co-Authors: Xiaotang Gan, Lixin Liu, Yani Yan, Chao Chen, Yongbo Zhou, Jianyu DongAbstract:Abstract A metal-free and two-phase protocol for the Meyer-Schuster isomerization of propargyl alcohols to the corresponding α,β-unsaturated carbonyl compounds has been achieved in the presence of stoichiometric phosphorous acid aqueous solution, which produces the desired products in high yields with excellent stereoselectivity. Compared with the traditional methods, the procedure features broad scope of the substrates, mild conditions, and easy separation, providing an appealing alternative to the Meyer-Schuster Reaction.