The Experts below are selected from a list of 870 Experts worldwide ranked by ideXlab platform
Andre Mermoud - One of the best experts on this subject based on the ideXlab platform.
-
Baerveldt tube implantation following failed deep Sclerectomy versus repeat deep Sclerectomy
Graefe's Archive for Clinical and Experimental Ophthalmology, 2016Co-Authors: Ciara Bergin, Emilie Ravinet, Andre Mermoud, Aleksandra Petrović, Eamon SharkawiAbstract:Purpose To compare the surgical outcomes of repeat deep Sclerectomy (DS) and the Baerveldt glaucoma implant (BGI) in eyes with failed primary deep Sclerectomy. Design A retrospective comparative case–control study. Methods Fifty-eight eyes of 56 glaucoma patients with previously failed DS underwent BGI (group BGI) and 58 eyes of 55 patients underwent repeat DS (group DS) at a tertiary referral centre. Visual acuity, intraocular pressure (IOP), number of glaucoma medications, surgical failure rates and complication rates were compared between groups. Surgical failure was defined as loss of IOP control, loss of light perception, or need for further glaucoma surgery. Results Baseline demographics were similar between groups. Preoperatively, median IOP was lower in the DS than the BGI group (19 mmHg versus 21 mmHg, p = 0.10). Postoperatively at year 1, median IOP was significantly higher in the DS than BGI group (14 mmHg versus 11 mmHg, p = 0.02). There were no differences between the DS and BGI groups in mean number of medications preoperatively (2.3 versus 2.6) or postoperatively (1.3 versus 1.1). Complication rates were significantly higher in the DS group [41 % ( n = 24) versus 14 % ( n = 8); p = 0.01]. The failure rate at 1 year was higher in eyes with repeat DS than in eyes with BGI (30 vs. 21 %, respectively; p = 0.07). Conclusions Baerveldt implants were more effective in lowering IOP and resulted in significantly fewer complications than repeat deep Sclerectomy in eyes with previously failed deep Sclerectomy.
-
Baerveldt tube implantation following failed deep Sclerectomy versus repeat deep Sclerectomy.
Graefes Archive for Clinical and Experimental Ophthalmology, 2015Co-Authors: Ciara Bergin, Emilie Ravinet, Andre Mermoud, Aleksandra Petrović, Eamon SharkawiAbstract:Purpose To compare the surgical outcomes of repeat deep Sclerectomy (DS) and the Baerveldt glaucoma implant (BGI) in eyes with failed primary deep Sclerectomy.
-
comparing deep Sclerectomy with collagen implant to the new method of very deep Sclerectomy with collagen implant a single masked randomized controlled trial
Journal of Glaucoma, 2010Co-Authors: Kaweh Mansouri, Emilie Ravinet, Hoai Viet Tran, Andre MermoudAbstract:AimTo prospectively study the intraocular pressure (IOP) lowering effect and safety of the new method of very deep Sclerectomy with collagen implant (VDSCI) compared with standard deep Sclerectomy with collagen implant (DSCI).MethodsThe trial involved 50 eyes of 48 patients with medically uncontroll
-
ten years follow up after deep Sclerectomy with collagen implant
Journal of Glaucoma, 2008Co-Authors: Alexandre Bissig, Andre Mermoud, Delphine Rivier, Marc Zaninetti, Tarek Shaarawy, Sylvain RoyAbstract:PurposeTo evaluate the long-term success rate and complications of nonpenetrating deep Sclerectomy with collagen implant in open-angle glaucoma.Patients and MethodsClinical, prospective, monocentric, nonrandomized, unmasked study on 105 patients with medically uncontrolled glaucoma. A standard proce
-
comparing polymethylmethacrylate implant with collagen implant in deep Sclerectomy a randomized controlled trial
Journal of Glaucoma, 2006Co-Authors: Kaweh Mansouri, Tarek Shaarawy, Andreas Wedrich, Andre MermoudAbstract:PURPOSE To compare the intraocular pressure (IOP) lowering effect and safety of a new rigid, nonabsorbable polymethylmethacrylate implant (PMMA) with the commercially available cylindrical collagen implant used in deep Sclerectomy procedure. INTERVENTION Nonpenetrating deep Sclerectomy was performed on all patients. Patients were randomly assigned to receive either a PMMA implant or a collagen implant. METHODS The trial involved 60 patients (60 eyes) with medically uncontrolled primary and secondary open-angle glaucoma who were randomized to receive either a PMMA implant (30 eyes) or the collagen implant (30 eyes). The patients were examined before and after the operation 1 day before surgery and at day 1; weeks 1, 2 and 3; and months 1, 2, 3, 6, 9, 12, 18, 24, and 30. At each visit, the following examinations were performed: slit lamp examination, tonometry, visual acuity, and fundoscopy. RESULTS The mean follow-up period was 20.4 (SD 12.4) months (PMMA) and 15.1 (SD 7.7) months (collagen) (P=NS). The mean preoperative IOP was 21.4 (SD 7.1) mm Hg (PMMA) and 21.0 mm Hg (SD 5.4) (collagen). The mean postoperative IOP was 7.4 (SD 4.5) mm Hg (PMMA) and 5.4 (SD 4.4) mm Hg (collagen) at day 1 (P=NS), 15.7 (SD 5.0) mm Hg (PMMA) and 14.7 (SD 5.0) mm Hg (collagen) at month 1 (P=NS), and 13.8 (SD 4.8) mm Hg (PMMA) and 13.3 (SD 2.4) mm Hg (collagen) at month 12 (P=NS). Seven patients had perforations of the trabeculo-Descemet membrane and were excluded from the analysis. At the last follow-up visit, 42% of PMMA patients and 44% of collagen patients achieved an IOP of 21 mm Hg or less without medication (P=NS). The number of medications was reduced from 2.4 (SD 1.0) to 0.6 (SD 0.6) (P<0.001) in the PMMA group, and from 2.4 (SD 1.1) to 0.7 (SD 0.8) (P<0.001) in the collagen group. There were no significant differences between the 2 groups in postoperative and transient complications. CONCLUSIONS The new PMMA implant offered success and complication rates equal to those of the collagen implant. The new PMMA implant could serve as a low-cost alternative to the collagen implant and render the use of deep Sclerectomy with an implant affordable for settings with limited financial resources.
Eamon Sharkawi - One of the best experts on this subject based on the ideXlab platform.
-
Baerveldt tube implantation following failed deep Sclerectomy versus repeat deep Sclerectomy
Graefe's Archive for Clinical and Experimental Ophthalmology, 2016Co-Authors: Ciara Bergin, Emilie Ravinet, Andre Mermoud, Aleksandra Petrović, Eamon SharkawiAbstract:Purpose To compare the surgical outcomes of repeat deep Sclerectomy (DS) and the Baerveldt glaucoma implant (BGI) in eyes with failed primary deep Sclerectomy. Design A retrospective comparative case–control study. Methods Fifty-eight eyes of 56 glaucoma patients with previously failed DS underwent BGI (group BGI) and 58 eyes of 55 patients underwent repeat DS (group DS) at a tertiary referral centre. Visual acuity, intraocular pressure (IOP), number of glaucoma medications, surgical failure rates and complication rates were compared between groups. Surgical failure was defined as loss of IOP control, loss of light perception, or need for further glaucoma surgery. Results Baseline demographics were similar between groups. Preoperatively, median IOP was lower in the DS than the BGI group (19 mmHg versus 21 mmHg, p = 0.10). Postoperatively at year 1, median IOP was significantly higher in the DS than BGI group (14 mmHg versus 11 mmHg, p = 0.02). There were no differences between the DS and BGI groups in mean number of medications preoperatively (2.3 versus 2.6) or postoperatively (1.3 versus 1.1). Complication rates were significantly higher in the DS group [41 % ( n = 24) versus 14 % ( n = 8); p = 0.01]. The failure rate at 1 year was higher in eyes with repeat DS than in eyes with BGI (30 vs. 21 %, respectively; p = 0.07). Conclusions Baerveldt implants were more effective in lowering IOP and resulted in significantly fewer complications than repeat deep Sclerectomy in eyes with previously failed deep Sclerectomy.
-
Baerveldt tube implantation following failed deep Sclerectomy versus repeat deep Sclerectomy.
Graefes Archive for Clinical and Experimental Ophthalmology, 2015Co-Authors: Ciara Bergin, Emilie Ravinet, Andre Mermoud, Aleksandra Petrović, Eamon SharkawiAbstract:Purpose To compare the surgical outcomes of repeat deep Sclerectomy (DS) and the Baerveldt glaucoma implant (BGI) in eyes with failed primary deep Sclerectomy.
Emilie Ravinet - One of the best experts on this subject based on the ideXlab platform.
-
Baerveldt tube implantation following failed deep Sclerectomy versus repeat deep Sclerectomy
Graefe's Archive for Clinical and Experimental Ophthalmology, 2016Co-Authors: Ciara Bergin, Emilie Ravinet, Andre Mermoud, Aleksandra Petrović, Eamon SharkawiAbstract:Purpose To compare the surgical outcomes of repeat deep Sclerectomy (DS) and the Baerveldt glaucoma implant (BGI) in eyes with failed primary deep Sclerectomy. Design A retrospective comparative case–control study. Methods Fifty-eight eyes of 56 glaucoma patients with previously failed DS underwent BGI (group BGI) and 58 eyes of 55 patients underwent repeat DS (group DS) at a tertiary referral centre. Visual acuity, intraocular pressure (IOP), number of glaucoma medications, surgical failure rates and complication rates were compared between groups. Surgical failure was defined as loss of IOP control, loss of light perception, or need for further glaucoma surgery. Results Baseline demographics were similar between groups. Preoperatively, median IOP was lower in the DS than the BGI group (19 mmHg versus 21 mmHg, p = 0.10). Postoperatively at year 1, median IOP was significantly higher in the DS than BGI group (14 mmHg versus 11 mmHg, p = 0.02). There were no differences between the DS and BGI groups in mean number of medications preoperatively (2.3 versus 2.6) or postoperatively (1.3 versus 1.1). Complication rates were significantly higher in the DS group [41 % ( n = 24) versus 14 % ( n = 8); p = 0.01]. The failure rate at 1 year was higher in eyes with repeat DS than in eyes with BGI (30 vs. 21 %, respectively; p = 0.07). Conclusions Baerveldt implants were more effective in lowering IOP and resulted in significantly fewer complications than repeat deep Sclerectomy in eyes with previously failed deep Sclerectomy.
-
Baerveldt tube implantation following failed deep Sclerectomy versus repeat deep Sclerectomy.
Graefes Archive for Clinical and Experimental Ophthalmology, 2015Co-Authors: Ciara Bergin, Emilie Ravinet, Andre Mermoud, Aleksandra Petrović, Eamon SharkawiAbstract:Purpose To compare the surgical outcomes of repeat deep Sclerectomy (DS) and the Baerveldt glaucoma implant (BGI) in eyes with failed primary deep Sclerectomy.
-
comparing deep Sclerectomy with collagen implant to the new method of very deep Sclerectomy with collagen implant a single masked randomized controlled trial
Journal of Glaucoma, 2010Co-Authors: Kaweh Mansouri, Emilie Ravinet, Hoai Viet Tran, Andre MermoudAbstract:AimTo prospectively study the intraocular pressure (IOP) lowering effect and safety of the new method of very deep Sclerectomy with collagen implant (VDSCI) compared with standard deep Sclerectomy with collagen implant (DSCI).MethodsThe trial involved 50 eyes of 48 patients with medically uncontroll
-
aqueous dynamic and histological findings after deep Sclerectomy with collagen implant in an animal model
British Journal of Ophthalmology, 2003Co-Authors: T Delarive, Emilie Ravinet, Tarek Shaarawy, A Rossier, S Rossier, Andre MermoudAbstract:Aim: The use of an animal model to study the aqueous dynamic and the histological findings after deep Sclerectomy with (DSCI) and without collagen implant. Methods: Deep Sclerectomy was performed on rabbits’ eyes. Eyes were randomly assigned to receive collagen implants. Measurements of intraocular pressure (IOP) and aqueous outflow facility using the constant pressure method through cannulation of the anterior chamber were performed. The system was filled with BSS and cationised ferritin. Histological assessment of the operative site was performed. Sections were stained with haematoxylin and eosin and with Prussian blue. Aqueous drainage vessels were identified by the reaction between ferritin and Prussian blue. All eyes were coded so that the investigator was blind to the type of surgery until the evaluation was completed. Results: A significant decrease in IOP (p Conclusion: A significant IOP decrease was observed during the first weeks after DSCI and DS. DS with or without collagen implant provided a significant increase in outflow facility throughout the 9 months of follow up. This might be partly explained by new drainage vessels in the sclera surrounding the operated site. Microscopic studies revealed the appearance of spindle cells lining the collagen implant in DSCI after 2 months.
Corinne C. Schnyder - One of the best experts on this subject based on the ideXlab platform.
-
comparative study between deep Sclerectomy with and without collagen implant long term follow up
British Journal of Ophthalmology, 2004Co-Authors: Tarek Shaarawy, Corinne C. Schnyder, C Nguyen, Andre MermoudAbstract:Aim: To identify the value of using collagen implant in deep Sclerectomy. Methods: A prospective randomised trial of 104 eyes (104 patients) with medically uncontrolled primary and secondary open angle glaucoma. All patients had deep Sclerectomy (DS), half of them with and the other half without a collagen implant (CI) sutured in the scleral bed. The main outcome measures were intraocular pressure (IOP), visual acuity, number of treatments preoperative and postoperative, and Nd:YAG goniopunctures. Results: Mean follow up period was 44.5 (SD 21) months for the DS group and 43.9 (SD 14) months for the deep Sclerectomy with a collagen implant (DSCI) group. The mean preoperative IOP was 23.3 (SD 7.2) mm Hg for the DS group and 25.6 (SD 4.9) mm Hg for the DSCI group. The mean IOP at the first postoperative day was 6.1 (SD 4.21) mm Hg for the DS group and 5.1 (SD 3.3) mm Hg for the DSCI group. At 48 months IOP was reduced by 40% (14 versus 23.3 mm Hg) for the DS group and by 50% (12.7 versus 25.6 mm Hg) for the DSCI group. Complete success rate, defined as IOP lower than 21 mm Hg without medication, was 34.6% (18/52 patients) at 48 months for the DS group, and 63.4% (33/52 patients) for the DSCI group. Qualified success rate; patients who achieved IOP below 21 mm Hg with or without medication, was 78.8% (41/52 patients) at 48 months and 94% (49/52 patients) for the DSCI group. The mean number of medications was reduced from 2.1 (SD 0.8) to 1.0 (SD 1) after DS, and was reduced from 2.2 (SD 0.7) to 0.4 (SD 0.6) in the DSCI group (p = 0.001) Conclusion: The use of a collagen implant in DS enhances the success rates and lowers the need for postoperative medication.
-
nd yag goniopuncture after deep Sclerectomy with collagen implant
Ophthalmic Surgery and Lasers, 1999Co-Authors: Andre Mermoud, Corinne C. Schnyder, Michel Sickenberg, Auguste G. Y. Chiou, Serge E. A. Hédiguer, M E Karlen, Enrique SanchezAbstract:■ BACKGROUND AND OBJECTIVE: To study the need, the safety and the success rate of Nd:Yag goniopuncture in eyes that underwent deep Sclerectomy with collagen implant. ■ PATIENTS AND METHODS: The first 100 patients that underwent deep Sclerectomy with collagen implant were prospectively followed. Deep Sclerectomy with collagen implant is a non-penetrating filtering surgery which allows filtration of aqueous from the anterior chamber to the subconjunctival space through a remaining trabeculo-Descemet's membrane without opening the anterior chamber. Goniopunctures with Nd:Yag laser were performed at the site of surgery when the filtration through the trabeculo-Descemet's membrane was considered to be insufficient with elevated intraocular pressure. The laser treatment was performed using a Lasag 15 gonioscopy contact lens (CGA1). Goniopunctures were performed using the free-running Q-switched mode with an energy ranging from 2 to 4 mJ. ■ RESULTS: Of 100 patients who underwent deep Sclerectomy with collagen implant, goniopunctures with Nd:Yag laser were performed in 41 patients (41%). The mean time between deep Sclerectomy with collagen implant and goniopuncture was 9.9 months ± 1.2 months (± SE). The mean IOP before laser treatment was 22.2 mm ± 7.0 mm Hg and decreased to 12.5 mm ± 5.8 mm Hg immediately after laser treatment and remained stable for the next 2 years of follow-up. The immediate success rate of goniopuncture was 83%. Choroidal detachment occurred in two patients (5%). ■ CONCLUSION: Nd:Yag goniopuncture is an efficient and safe treatment for low filtration through the trabeculo-Descemet's membrane after deep Sclerectomy with collagen implant.
-
deep Sclerectomy with collagen implant medium term results
British Journal of Ophthalmology, 1999Co-Authors: Marc Karlen, Corinne C. Schnyder, Enrique Sanchez, Michel Sickenberg, Andre MermoudAbstract:AIMS—To study prospectively the success rate and complications of deep Sclerectomy with collagen implant (DSCI), a new non-penetrating filtration procedure. METHODS—Non-randomised prospective trial involving consecutive patients. 100 eyes of 100 patients with medically uncontrolled primary and secondary open angle glaucoma. A superficial scleral flap was raised and a deep Sclerectomy was performed in the scleral bed. Schlemm's canal was opened and dissection of the cornea was performed up to Descemet's membrane, at which point aqueous percolated through the remaining trabeculo-Descemet's membrane. A collagen implant was sutured radially in the scleral bed. Visual acuity, intraocular pressure (IOP) measurements, and slit lamp examinations were performed before surgery and after surgery at 1 and 7 days, and 1, 3, 6, 9, 12, 18, 24, 30, and 36 months. RESULTS—The mean follow up period was 17.8 (SD 8.7) months. The mean preoperative IOP was 27.8 (8.6) mm Hg; the mean postoperative IOP was 5.7 (4.0) at day 1, 11.2 (4.6) at month 1, 14.0 (3.5) at month 12, and 13.0 (3.8) at month 36. Complete success rate, defined as an IOP lower than 21 mm Hg without medication, was 44.6% at 36 months. Qualified success rate, defined as an IOP lower than 21 mm Hg with medication, was 97.7% at 36 months. Early postoperative complications included hyphaema in seven patients, wound leak in 10 patients, and subtle choroidal detachment in 11 patients. Goniopuncture was performed in 41 of the patients, and 5-fluorouracil injections were made in 23 patients; cataract progression occurred in seven patients. When comparing the different types of open angle glaucoma, no difference was found in terms of reduction in IOP, number of patients requiring antiglaucoma medications, or success rate. CONCLUSIONS—Deep Sclerectomy with collagen implant appears to provide reasonable control of IOP at medium term follow up, with few immediate postoperative complications. Keywords: deep Sclerectomy; glaucoma surgery; collagen implant
-
an ultrasound biomicroscopic study of eyes after deep Sclerectomy with collagen implant
Ophthalmology, 1998Co-Authors: Auguste G. Y. Chiou, Andre Mermoud, Jerald P Underdahl, Corinne C. SchnyderAbstract:Abstract Objective This study aimed to assess the natural history of eyes after deep Sclerectomy with collagen implant (DSCI), a nonperforating glaucoma-filtering surgery. Design The design was a prospective, longitudinal, observational, and nonrandomized study. Participants Forty-five eyes of 41 patients with medically uncontrolled open-angle glaucoma were studied. Intervention Deep Sclerectomy with collagen implant was performed. Main outcome measures Ultrasound biomicroscopy (UBM) of the Sclerectomy site was performed 1, 2, 3, 6, 9, 12, and 18 months after surgery. The following parameters were assessed: length and height of the collagen implant, thickness of the residual trabeculodescemetic membrane, and bleb appearance. Results Mean intraocular pressure decreased from a preoperative value of 26.3 ± 3.5 mmHg (mean ± standard deviation) to a postoperative value of 16.6 ± 3.1 mmHg (mean ± standard deviation) at 18 months ( P Conclusions The UBM findings are consistent with intraocular pressure lowering by aqueous filtration through the thin remaining trabeculodescemetic membrane to an area under the scleral flap, which was maintained open by the collagen implant. The authors speculate that aqueous humor then reached the subconjunctival space and, eventually, was filtered through the thin scleral wall into the suprachoroidal space. Complete resorption of the collagen implant occurred between 6 and 9 months after surgery.
-
ultrasound biomicroscopy of eyes undergoing deep Sclerectomy with collagen implant
British Journal of Ophthalmology, 1996Co-Authors: Auguste G. Y. Chiou, Andre Mermoud, Corinne C. Schnyder, Serge E. A. Hédiguer, R FaggioniAbstract:AIMS--To assess the intraocular pressure (IOP) lowering mechanism of deep Sclerectomy with collagen implant (DSCI), a non-penetrating glaucoma surgery. METHODS--Nine eyes of nine patients with medically uncontrolled open angle glaucoma underwent DSCI. Ultrasound biomicroscopy (UBM) of the Sclerectomy site was performed 1 month after surgery. The following factors were assessed: length and height of collagen implant, and thickness of the residual trabeculocorneal membrane. RESULTS--Postoperative IOP decreased significantly in all nine eyes from a preoperative mean value of 25.8 (SD 4.8) mm Hg to a postoperative (1 month) mean value of 11.3 (6.3) mm Hg (p = 0.001). In all nine eyes, UBM at 1 month after surgery showed a subconjunctival filtration through the thin trabeculocorneal membrane and through the scleral flap around the collagen implant. In four cases, a hypoechoic area in the suprachoroidal space was observed and might represent ciliary body detachment or be due to suprachoroidal drainage of aqueous humour through the thin deep scleral wall. At 1 month after surgery the mean trabeculocorneal membrane thickness was 110.1 (16.8) microns, and the mean length and height of the collagen implant were 2.3 (0.1) mm and 1.1 (0.1) mm respectively. CONCLUSION--DSCI lowered IOP by allowing aqueous filtration through a thin trabeculocorneal membrane to the subconjunctival space and, eventually, to the suprachoroidal space.
Ciara Bergin - One of the best experts on this subject based on the ideXlab platform.
-
Baerveldt tube implantation following failed deep Sclerectomy versus repeat deep Sclerectomy
Graefe's Archive for Clinical and Experimental Ophthalmology, 2016Co-Authors: Ciara Bergin, Emilie Ravinet, Andre Mermoud, Aleksandra Petrović, Eamon SharkawiAbstract:Purpose To compare the surgical outcomes of repeat deep Sclerectomy (DS) and the Baerveldt glaucoma implant (BGI) in eyes with failed primary deep Sclerectomy. Design A retrospective comparative case–control study. Methods Fifty-eight eyes of 56 glaucoma patients with previously failed DS underwent BGI (group BGI) and 58 eyes of 55 patients underwent repeat DS (group DS) at a tertiary referral centre. Visual acuity, intraocular pressure (IOP), number of glaucoma medications, surgical failure rates and complication rates were compared between groups. Surgical failure was defined as loss of IOP control, loss of light perception, or need for further glaucoma surgery. Results Baseline demographics were similar between groups. Preoperatively, median IOP was lower in the DS than the BGI group (19 mmHg versus 21 mmHg, p = 0.10). Postoperatively at year 1, median IOP was significantly higher in the DS than BGI group (14 mmHg versus 11 mmHg, p = 0.02). There were no differences between the DS and BGI groups in mean number of medications preoperatively (2.3 versus 2.6) or postoperatively (1.3 versus 1.1). Complication rates were significantly higher in the DS group [41 % ( n = 24) versus 14 % ( n = 8); p = 0.01]. The failure rate at 1 year was higher in eyes with repeat DS than in eyes with BGI (30 vs. 21 %, respectively; p = 0.07). Conclusions Baerveldt implants were more effective in lowering IOP and resulted in significantly fewer complications than repeat deep Sclerectomy in eyes with previously failed deep Sclerectomy.
-
Baerveldt tube implantation following failed deep Sclerectomy versus repeat deep Sclerectomy.
Graefes Archive for Clinical and Experimental Ophthalmology, 2015Co-Authors: Ciara Bergin, Emilie Ravinet, Andre Mermoud, Aleksandra Petrović, Eamon SharkawiAbstract:Purpose To compare the surgical outcomes of repeat deep Sclerectomy (DS) and the Baerveldt glaucoma implant (BGI) in eyes with failed primary deep Sclerectomy.
