The Experts below are selected from a list of 117 Experts worldwide ranked by ideXlab platform

Kara Zivin - One of the best experts on this subject based on the ideXlab platform.

  • the cost effectiveness of cognitive behavioral therapy versus second generation Antidepressants for initial treatment of major depressive disorder in the united states a decision analytic model
    Annals of Internal Medicine, 2019
    Co-Authors: Eric L. Ross, Sandeep Vijan, Erin M. Miller, Marcia Valenstein, Kara Zivin
    Abstract:

    Background: Most guidelines for major depressive disorder recommend initial treatment with either a Second-Generation Antidepressant (SGA) or cognitive behavioral therapy (CBT). Although most trials suggest that these treatments have similar efficacy, their health economic implications are uncertain. Objective: To quantify the cost-effectiveness of CBT versus SGA for initial treatment of depression. Design: Decision analytic model. Data Sources: Relative effectiveness data from a meta-analysis of randomized controlled trials; additional clinical and economic data from other publications. Target Population: Adults with newly diagnosed major depressive disorder in the United States. Time Horizon: 1 to 5 years. Perspectives: Health care sector and societal. Intervention: Initial treatment with either an SGA or group and individual CBT. Outcome Measures: Costs in 2014 U.S. dollars, quality-adjusted life-years (QALYs), and incremental cost-effectiveness ratios. Results of Base-Case Analysis: In model projections, CBT produced higher QALYs (3 days more at 1 year and 20 days more at 5 years) with higher costs at 1 year (health care sector, $900; societal, $1500) but lower costs at 5 years (health care sector, -$1800; societal, -$2500). Results of Sensitivity Analysis: In probabilistic sensitivity analyses, SGA had a 64% to 77% likelihood of having an incremental cost-effectiveness ratio of $100 000 or less per QALY at 1 year; CBT had a 73% to 77% likelihood at 5 years. Uncertainty in the relative risk for relapse of depression contributed the most to overall uncertainty in the optimal treatment. Limitation: Long-term trials comparing CBT and SGA are lacking. Conclusion: Neither SGAs nor CBT provides consistently superior cost-effectiveness relative to the other. Given many patients' preference for psychotherapy over pharmacotherapy, increasing patient access to CBT may be warranted. Primary Funding Source: Department of Veterans Affairs, National Institute of Mental Health.

  • The Cost-Effectiveness of Cognitive Behavioral Therapy Versus Second-Generation Antidepressants for Initial Treatment of Major Depressive Disorder in the United States
    Annals of Internal Medicine, 2019
    Co-Authors: Eric L. Ross, Sandeep Vijan, Erin M. Miller, Marcia Valenstein, Kara Zivin
    Abstract:

    The authors created a computer model to examine whether cognitive behavioral therapy or a Second-Generation Antidepressant provides better health economic value for major depressive disorder.

Eric L. Ross - One of the best experts on this subject based on the ideXlab platform.

  • the cost effectiveness of cognitive behavioral therapy versus second generation Antidepressants for initial treatment of major depressive disorder in the united states a decision analytic model
    Annals of Internal Medicine, 2019
    Co-Authors: Eric L. Ross, Sandeep Vijan, Erin M. Miller, Marcia Valenstein, Kara Zivin
    Abstract:

    Background: Most guidelines for major depressive disorder recommend initial treatment with either a Second-Generation Antidepressant (SGA) or cognitive behavioral therapy (CBT). Although most trials suggest that these treatments have similar efficacy, their health economic implications are uncertain. Objective: To quantify the cost-effectiveness of CBT versus SGA for initial treatment of depression. Design: Decision analytic model. Data Sources: Relative effectiveness data from a meta-analysis of randomized controlled trials; additional clinical and economic data from other publications. Target Population: Adults with newly diagnosed major depressive disorder in the United States. Time Horizon: 1 to 5 years. Perspectives: Health care sector and societal. Intervention: Initial treatment with either an SGA or group and individual CBT. Outcome Measures: Costs in 2014 U.S. dollars, quality-adjusted life-years (QALYs), and incremental cost-effectiveness ratios. Results of Base-Case Analysis: In model projections, CBT produced higher QALYs (3 days more at 1 year and 20 days more at 5 years) with higher costs at 1 year (health care sector, $900; societal, $1500) but lower costs at 5 years (health care sector, -$1800; societal, -$2500). Results of Sensitivity Analysis: In probabilistic sensitivity analyses, SGA had a 64% to 77% likelihood of having an incremental cost-effectiveness ratio of $100 000 or less per QALY at 1 year; CBT had a 73% to 77% likelihood at 5 years. Uncertainty in the relative risk for relapse of depression contributed the most to overall uncertainty in the optimal treatment. Limitation: Long-term trials comparing CBT and SGA are lacking. Conclusion: Neither SGAs nor CBT provides consistently superior cost-effectiveness relative to the other. Given many patients' preference for psychotherapy over pharmacotherapy, increasing patient access to CBT may be warranted. Primary Funding Source: Department of Veterans Affairs, National Institute of Mental Health.

  • The Cost-Effectiveness of Cognitive Behavioral Therapy Versus Second-Generation Antidepressants for Initial Treatment of Major Depressive Disorder in the United States
    Annals of Internal Medicine, 2019
    Co-Authors: Eric L. Ross, Sandeep Vijan, Erin M. Miller, Marcia Valenstein, Kara Zivin
    Abstract:

    The authors created a computer model to examine whether cognitive behavioral therapy or a Second-Generation Antidepressant provides better health economic value for major depressive disorder.

Sandeep Vijan - One of the best experts on this subject based on the ideXlab platform.

  • the cost effectiveness of cognitive behavioral therapy versus second generation Antidepressants for initial treatment of major depressive disorder in the united states a decision analytic model
    Annals of Internal Medicine, 2019
    Co-Authors: Eric L. Ross, Sandeep Vijan, Erin M. Miller, Marcia Valenstein, Kara Zivin
    Abstract:

    Background: Most guidelines for major depressive disorder recommend initial treatment with either a Second-Generation Antidepressant (SGA) or cognitive behavioral therapy (CBT). Although most trials suggest that these treatments have similar efficacy, their health economic implications are uncertain. Objective: To quantify the cost-effectiveness of CBT versus SGA for initial treatment of depression. Design: Decision analytic model. Data Sources: Relative effectiveness data from a meta-analysis of randomized controlled trials; additional clinical and economic data from other publications. Target Population: Adults with newly diagnosed major depressive disorder in the United States. Time Horizon: 1 to 5 years. Perspectives: Health care sector and societal. Intervention: Initial treatment with either an SGA or group and individual CBT. Outcome Measures: Costs in 2014 U.S. dollars, quality-adjusted life-years (QALYs), and incremental cost-effectiveness ratios. Results of Base-Case Analysis: In model projections, CBT produced higher QALYs (3 days more at 1 year and 20 days more at 5 years) with higher costs at 1 year (health care sector, $900; societal, $1500) but lower costs at 5 years (health care sector, -$1800; societal, -$2500). Results of Sensitivity Analysis: In probabilistic sensitivity analyses, SGA had a 64% to 77% likelihood of having an incremental cost-effectiveness ratio of $100 000 or less per QALY at 1 year; CBT had a 73% to 77% likelihood at 5 years. Uncertainty in the relative risk for relapse of depression contributed the most to overall uncertainty in the optimal treatment. Limitation: Long-term trials comparing CBT and SGA are lacking. Conclusion: Neither SGAs nor CBT provides consistently superior cost-effectiveness relative to the other. Given many patients' preference for psychotherapy over pharmacotherapy, increasing patient access to CBT may be warranted. Primary Funding Source: Department of Veterans Affairs, National Institute of Mental Health.

  • The Cost-Effectiveness of Cognitive Behavioral Therapy Versus Second-Generation Antidepressants for Initial Treatment of Major Depressive Disorder in the United States
    Annals of Internal Medicine, 2019
    Co-Authors: Eric L. Ross, Sandeep Vijan, Erin M. Miller, Marcia Valenstein, Kara Zivin
    Abstract:

    The authors created a computer model to examine whether cognitive behavioral therapy or a Second-Generation Antidepressant provides better health economic value for major depressive disorder.

Erin M. Miller - One of the best experts on this subject based on the ideXlab platform.

  • the cost effectiveness of cognitive behavioral therapy versus second generation Antidepressants for initial treatment of major depressive disorder in the united states a decision analytic model
    Annals of Internal Medicine, 2019
    Co-Authors: Eric L. Ross, Sandeep Vijan, Erin M. Miller, Marcia Valenstein, Kara Zivin
    Abstract:

    Background: Most guidelines for major depressive disorder recommend initial treatment with either a Second-Generation Antidepressant (SGA) or cognitive behavioral therapy (CBT). Although most trials suggest that these treatments have similar efficacy, their health economic implications are uncertain. Objective: To quantify the cost-effectiveness of CBT versus SGA for initial treatment of depression. Design: Decision analytic model. Data Sources: Relative effectiveness data from a meta-analysis of randomized controlled trials; additional clinical and economic data from other publications. Target Population: Adults with newly diagnosed major depressive disorder in the United States. Time Horizon: 1 to 5 years. Perspectives: Health care sector and societal. Intervention: Initial treatment with either an SGA or group and individual CBT. Outcome Measures: Costs in 2014 U.S. dollars, quality-adjusted life-years (QALYs), and incremental cost-effectiveness ratios. Results of Base-Case Analysis: In model projections, CBT produced higher QALYs (3 days more at 1 year and 20 days more at 5 years) with higher costs at 1 year (health care sector, $900; societal, $1500) but lower costs at 5 years (health care sector, -$1800; societal, -$2500). Results of Sensitivity Analysis: In probabilistic sensitivity analyses, SGA had a 64% to 77% likelihood of having an incremental cost-effectiveness ratio of $100 000 or less per QALY at 1 year; CBT had a 73% to 77% likelihood at 5 years. Uncertainty in the relative risk for relapse of depression contributed the most to overall uncertainty in the optimal treatment. Limitation: Long-term trials comparing CBT and SGA are lacking. Conclusion: Neither SGAs nor CBT provides consistently superior cost-effectiveness relative to the other. Given many patients' preference for psychotherapy over pharmacotherapy, increasing patient access to CBT may be warranted. Primary Funding Source: Department of Veterans Affairs, National Institute of Mental Health.

  • The Cost-Effectiveness of Cognitive Behavioral Therapy Versus Second-Generation Antidepressants for Initial Treatment of Major Depressive Disorder in the United States
    Annals of Internal Medicine, 2019
    Co-Authors: Eric L. Ross, Sandeep Vijan, Erin M. Miller, Marcia Valenstein, Kara Zivin
    Abstract:

    The authors created a computer model to examine whether cognitive behavioral therapy or a Second-Generation Antidepressant provides better health economic value for major depressive disorder.

Marcia Valenstein - One of the best experts on this subject based on the ideXlab platform.

  • the cost effectiveness of cognitive behavioral therapy versus second generation Antidepressants for initial treatment of major depressive disorder in the united states a decision analytic model
    Annals of Internal Medicine, 2019
    Co-Authors: Eric L. Ross, Sandeep Vijan, Erin M. Miller, Marcia Valenstein, Kara Zivin
    Abstract:

    Background: Most guidelines for major depressive disorder recommend initial treatment with either a Second-Generation Antidepressant (SGA) or cognitive behavioral therapy (CBT). Although most trials suggest that these treatments have similar efficacy, their health economic implications are uncertain. Objective: To quantify the cost-effectiveness of CBT versus SGA for initial treatment of depression. Design: Decision analytic model. Data Sources: Relative effectiveness data from a meta-analysis of randomized controlled trials; additional clinical and economic data from other publications. Target Population: Adults with newly diagnosed major depressive disorder in the United States. Time Horizon: 1 to 5 years. Perspectives: Health care sector and societal. Intervention: Initial treatment with either an SGA or group and individual CBT. Outcome Measures: Costs in 2014 U.S. dollars, quality-adjusted life-years (QALYs), and incremental cost-effectiveness ratios. Results of Base-Case Analysis: In model projections, CBT produced higher QALYs (3 days more at 1 year and 20 days more at 5 years) with higher costs at 1 year (health care sector, $900; societal, $1500) but lower costs at 5 years (health care sector, -$1800; societal, -$2500). Results of Sensitivity Analysis: In probabilistic sensitivity analyses, SGA had a 64% to 77% likelihood of having an incremental cost-effectiveness ratio of $100 000 or less per QALY at 1 year; CBT had a 73% to 77% likelihood at 5 years. Uncertainty in the relative risk for relapse of depression contributed the most to overall uncertainty in the optimal treatment. Limitation: Long-term trials comparing CBT and SGA are lacking. Conclusion: Neither SGAs nor CBT provides consistently superior cost-effectiveness relative to the other. Given many patients' preference for psychotherapy over pharmacotherapy, increasing patient access to CBT may be warranted. Primary Funding Source: Department of Veterans Affairs, National Institute of Mental Health.

  • The Cost-Effectiveness of Cognitive Behavioral Therapy Versus Second-Generation Antidepressants for Initial Treatment of Major Depressive Disorder in the United States
    Annals of Internal Medicine, 2019
    Co-Authors: Eric L. Ross, Sandeep Vijan, Erin M. Miller, Marcia Valenstein, Kara Zivin
    Abstract:

    The authors created a computer model to examine whether cognitive behavioral therapy or a Second-Generation Antidepressant provides better health economic value for major depressive disorder.