The Experts below are selected from a list of 360 Experts worldwide ranked by ideXlab platform
Jan-e. Bäckvall - One of the best experts on this subject based on the ideXlab platform.
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combined ruthenium ii and lipase catalysis for efficient dynamic kinetic resolution of Secondary Alcohols insight into the racemization mechanism
Journal of the American Chemical Society, 2005Co-Authors: Belen Martinmatute, Michaela Edin, Krisztian Bogar, Betul F Kaynak, Jan-e. BäckvallAbstract:Combined Ruthenium(II) and Lipase Catalysis for Efficient Dynamic Kinetic Resolution of Secondary Alcohols. Insight into the Racemization Mechanism
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Ruthenium- and Enzyme-Catalyzed Dynamic Kinetic Resolution of Secondary Alcohols
Journal of the American Chemical Society, 1999Co-Authors: B. Anders Persson, Anna L. E. Larsson, Jan-e. BäckvallAbstract:Enzymatic resolution of Secondary Alcohols under substrate racemizing conditions was studied using an immobilized lipase from Candida antarctica in the presence of a ruthenium catalyst. A specifically designed acyl donor, 4-chlorophenyl acetate, was found to be compatible with both catalysts and resulted in an efficient dynamic kinetic resolution. Studies of the reaction in different solvents showed that nonpolar solvents gave the best results. With this process, a variety of racemic Secondary Alcohols were transformed to the corresponding enantiomerically pure acetates, making efficient use of all starting material. In most cases, the reaction proceeded with >99% ee and in good yield.
Zhiqiang Shen - One of the best experts on this subject based on the ideXlab platform.
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enantioselective oxidation of racemic Secondary Alcohols catalyzed by chiral mn iii salen complexes with n bromosuccinimide as a powerful oxidant
ChemInform, 2012Co-Authors: Daqian Xu, Shoufeng Wang, Zhiqiang ShenAbstract:The methodology works efficiently for numerous Secondary Alcohols including benzylic Alcohols with ortho substituted aromatic rings.
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enantioselective oxidation of racemic Secondary Alcohols catalyzed by chiral mn iii salen complexes with n bromosuccinimide as a powerful oxidant
Organic and Biomolecular Chemistry, 2012Co-Authors: Daqian Xu, Shoufeng Wang, Zhiqiang ShenAbstract:We demonstrate an efficient enantioselective oxidation of Secondary Alcohols catalyzed by Mn(III)-salen complex using N-bromosuccinimide (NBS) as the oxidant. The new protocol is very efficient for the oxidative kinetic resolution of a variety of Secondary Alcohols, including ortho-substituted benzylic Alcohols.
David Milstein - One of the best experts on this subject based on the ideXlab platform.
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direct synthesis of pyridines and quinolines by coupling of γ amino Alcohols with Secondary Alcohols liberating h2 catalyzed by ruthenium pincer complexes
ChemInform, 2013Co-Authors: Dipankar Srimani, Yehoshoa Bendavid, David MilsteinAbstract:A novel, one-step synthesis of substituted pyridine- and quinoline-derivatives was achieved by acceptorless dehydrogenative coupling of γ-aminoAlcohols with Secondary Alcohols. The reaction involves consecutive C–N and C–C bond formation, catalyzed by a bipyridyl-based ruthenium pincer complex with a base.
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ruthenium pincer catalyzed cross dehydrogenative coupling of primary Alcohols with Secondary Alcohols under neutral conditions
Advanced Synthesis & Catalysis, 2012Co-Authors: Dipankar Srimani, Ekambaram Balaraman, Boopathy Gnanaprakasam, Yehoshoa Bendavid, David MilsteinAbstract:Cross-dehydrogenative coupling of primary Alcohols with Secondary Alcohols to obtain mixed esters with the liberation of molecular hydrogen is achieved in high yield and good selectivity under neutral conditions, using a bipyridyl-based PNN ruthenium(II) pincer catalyst.
Zhenlu Shen - One of the best experts on this subject based on the ideXlab platform.
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aerobic oxidation of Secondary Alcohols in water with abno tert butyl nitrite kpf6 catalytic system
Tetrahedron Letters, 2017Co-Authors: Chao Hong, Nan Sun, Yan Wan, Liqun Jin, Zhenlu ShenAbstract:A green and efficient transition-metal free ABNO/tert-butyl nitrite/KPF6-catalyzed aerobic oxidation of Secondary Alcohols in water has been achieved. Under the optimal reaction conditions, a number of Secondary aliphatic Alcohols and Secondary benzylic Alcohols can be converted to their corresponding ketones in excellent yields (up to 99%).
Daqian Xu - One of the best experts on this subject based on the ideXlab platform.
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enantioselective oxidation of racemic Secondary Alcohols catalyzed by chiral mn iii salen complexes with n bromosuccinimide as a powerful oxidant
ChemInform, 2012Co-Authors: Daqian Xu, Shoufeng Wang, Zhiqiang ShenAbstract:The methodology works efficiently for numerous Secondary Alcohols including benzylic Alcohols with ortho substituted aromatic rings.
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enantioselective oxidation of racemic Secondary Alcohols catalyzed by chiral mn iii salen complexes with n bromosuccinimide as a powerful oxidant
Organic and Biomolecular Chemistry, 2012Co-Authors: Daqian Xu, Shoufeng Wang, Zhiqiang ShenAbstract:We demonstrate an efficient enantioselective oxidation of Secondary Alcohols catalyzed by Mn(III)-salen complex using N-bromosuccinimide (NBS) as the oxidant. The new protocol is very efficient for the oxidative kinetic resolution of a variety of Secondary Alcohols, including ortho-substituted benzylic Alcohols.
