The Experts below are selected from a list of 12882 Experts worldwide ranked by ideXlab platform
Fajun Miao - One of the best experts on this subject based on the ideXlab platform.
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A new Hg2+ fluorescent Sensors based on 1,3-alternate thiacalix[4]arene (L) and the complex of [L+Hg2+] as turn-on Sensor for cysteine
Tetrahedron, 2012Co-Authors: Fajun Miao, Junyan Zhan, Zhilong Zou, Deimei TianAbstract:Abstract A new thiacalix[4]arene derivative in a 1,3-alternate conformation bearing four naphthalene groups through crown-3 chains has been synthesized, which exhibits high selectivity toward Hg 2+ by forming a 1:2 complex, among other metal ions ( Na + , K + , Mg 2+ , Ba 2+ , Ca 2+ , Sr 2+ , Cs + , Mn 2+ , Fe 2+ , Cd 2+ , Co 2+ , Ni 2+ , Cu 2+ , Li + , and Zn 2+ ) with a low detection limit (3.30×10 −7 M). The metal ion-binding properties were studied by fluorescence, AFM, and 1 H NMR spectroscopy. The in situ prepared [Hg 2+ +L] complex shows well recognition ability for cysteine with a low detection limit (2.23×10 −7 M) through fluorescence turning on. The mechanism of fluorescence turning on is the host L releasing from [L+Hg 2+ ] for [Cys+Hg 2+ ] complex formed. Thus the paper reports Secondary-Sensor design: Hg 2+ as a first Sensor for [L+Hg 2+ ] form, cysteine as a second Sensor for Hg 2+ releasing from the [L+Hg 2+ ] complex after cysteine adding in.
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synthesis of triazolo thiadiazole fluorescent organic nanoparticles as primary Sensor toward ag and the complex of ag as Secondary Sensor toward cysteine
Sensors and Actuators B-chemical, 2011Co-Authors: Huijuan Yan, Demei Tian, Fajun MiaoAbstract:Abstract Fluorescent organic nanoparticles (FONs) have received considerable attention in the past few years, since the material holds great flexibility in materials synthesis and optical properties. In this study, we report a novel Ag + -selective turn-on fluorescent chemoSensor based on the triazolo-thiadiazole (TTD) FONs, which show a significant fluorescence enhancement to silver ions among fourteen metal ions due to the formation of Ag–FONs cation complex, and also exhibit a lowest detectable concentration of 2.87 × 10 −9 M. Upon the addition of Cysteine (Cys), a thiol-containing amino acid, the fluorescence intensity of the colloidal solution decreases significantly with a limit detection concentration of 2.58 × 10 −7 M, indicating that Cys can form the Ag–Cys complex. Thus FONs are a potential primary Sensor toward Ag + and a Secondary Sensor toward Cys. The method is a basis for further two-component recognition study of TTD FONs. The possible mechanism is also discussed.
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Synthesis of triazolo-thiadiazole fluorescent organic nanoparticles as primary Sensor toward Ag+ and the complex of Ag+ as Secondary Sensor toward cysteine
Sensors and Actuators B: Chemical, 2011Co-Authors: Huijuan Yan, Demei Tian, Fajun MiaoAbstract:Abstract Fluorescent organic nanoparticles (FONs) have received considerable attention in the past few years, since the material holds great flexibility in materials synthesis and optical properties. In this study, we report a novel Ag + -selective turn-on fluorescent chemoSensor based on the triazolo-thiadiazole (TTD) FONs, which show a significant fluorescence enhancement to silver ions among fourteen metal ions due to the formation of Ag–FONs cation complex, and also exhibit a lowest detectable concentration of 2.87 × 10 −9 M. Upon the addition of Cysteine (Cys), a thiol-containing amino acid, the fluorescence intensity of the colloidal solution decreases significantly with a limit detection concentration of 2.58 × 10 −7 M, indicating that Cys can form the Ag–Cys complex. Thus FONs are a potential primary Sensor toward Ag + and a Secondary Sensor toward Cys. The method is a basis for further two-component recognition study of TTD FONs. The possible mechanism is also discussed.
Huijuan Yan - One of the best experts on this subject based on the ideXlab platform.
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synthesis of triazolo thiadiazole fluorescent organic nanoparticles as primary Sensor toward ag and the complex of ag as Secondary Sensor toward cysteine
Sensors and Actuators B-chemical, 2011Co-Authors: Huijuan Yan, Demei Tian, Fajun MiaoAbstract:Abstract Fluorescent organic nanoparticles (FONs) have received considerable attention in the past few years, since the material holds great flexibility in materials synthesis and optical properties. In this study, we report a novel Ag + -selective turn-on fluorescent chemoSensor based on the triazolo-thiadiazole (TTD) FONs, which show a significant fluorescence enhancement to silver ions among fourteen metal ions due to the formation of Ag–FONs cation complex, and also exhibit a lowest detectable concentration of 2.87 × 10 −9 M. Upon the addition of Cysteine (Cys), a thiol-containing amino acid, the fluorescence intensity of the colloidal solution decreases significantly with a limit detection concentration of 2.58 × 10 −7 M, indicating that Cys can form the Ag–Cys complex. Thus FONs are a potential primary Sensor toward Ag + and a Secondary Sensor toward Cys. The method is a basis for further two-component recognition study of TTD FONs. The possible mechanism is also discussed.
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Synthesis of triazolo-thiadiazole fluorescent organic nanoparticles as primary Sensor toward Ag+ and the complex of Ag+ as Secondary Sensor toward cysteine
Sensors and Actuators B: Chemical, 2011Co-Authors: Huijuan Yan, Demei Tian, Fajun MiaoAbstract:Abstract Fluorescent organic nanoparticles (FONs) have received considerable attention in the past few years, since the material holds great flexibility in materials synthesis and optical properties. In this study, we report a novel Ag + -selective turn-on fluorescent chemoSensor based on the triazolo-thiadiazole (TTD) FONs, which show a significant fluorescence enhancement to silver ions among fourteen metal ions due to the formation of Ag–FONs cation complex, and also exhibit a lowest detectable concentration of 2.87 × 10 −9 M. Upon the addition of Cysteine (Cys), a thiol-containing amino acid, the fluorescence intensity of the colloidal solution decreases significantly with a limit detection concentration of 2.58 × 10 −7 M, indicating that Cys can form the Ag–Cys complex. Thus FONs are a potential primary Sensor toward Ag + and a Secondary Sensor toward Cys. The method is a basis for further two-component recognition study of TTD FONs. The possible mechanism is also discussed.
Demei Tian - One of the best experts on this subject based on the ideXlab platform.
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synthesis of triazolo thiadiazole fluorescent organic nanoparticles as primary Sensor toward ag and the complex of ag as Secondary Sensor toward cysteine
Sensors and Actuators B-chemical, 2011Co-Authors: Huijuan Yan, Demei Tian, Fajun MiaoAbstract:Abstract Fluorescent organic nanoparticles (FONs) have received considerable attention in the past few years, since the material holds great flexibility in materials synthesis and optical properties. In this study, we report a novel Ag + -selective turn-on fluorescent chemoSensor based on the triazolo-thiadiazole (TTD) FONs, which show a significant fluorescence enhancement to silver ions among fourteen metal ions due to the formation of Ag–FONs cation complex, and also exhibit a lowest detectable concentration of 2.87 × 10 −9 M. Upon the addition of Cysteine (Cys), a thiol-containing amino acid, the fluorescence intensity of the colloidal solution decreases significantly with a limit detection concentration of 2.58 × 10 −7 M, indicating that Cys can form the Ag–Cys complex. Thus FONs are a potential primary Sensor toward Ag + and a Secondary Sensor toward Cys. The method is a basis for further two-component recognition study of TTD FONs. The possible mechanism is also discussed.
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Synthesis of triazolo-thiadiazole fluorescent organic nanoparticles as primary Sensor toward Ag+ and the complex of Ag+ as Secondary Sensor toward cysteine
Sensors and Actuators B: Chemical, 2011Co-Authors: Huijuan Yan, Demei Tian, Fajun MiaoAbstract:Abstract Fluorescent organic nanoparticles (FONs) have received considerable attention in the past few years, since the material holds great flexibility in materials synthesis and optical properties. In this study, we report a novel Ag + -selective turn-on fluorescent chemoSensor based on the triazolo-thiadiazole (TTD) FONs, which show a significant fluorescence enhancement to silver ions among fourteen metal ions due to the formation of Ag–FONs cation complex, and also exhibit a lowest detectable concentration of 2.87 × 10 −9 M. Upon the addition of Cysteine (Cys), a thiol-containing amino acid, the fluorescence intensity of the colloidal solution decreases significantly with a limit detection concentration of 2.58 × 10 −7 M, indicating that Cys can form the Ag–Cys complex. Thus FONs are a potential primary Sensor toward Ag + and a Secondary Sensor toward Cys. The method is a basis for further two-component recognition study of TTD FONs. The possible mechanism is also discussed.
Narinder Singh - One of the best experts on this subject based on the ideXlab platform.
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a highly selective fluorescent turn on chemoSensor for zn2 based on a benzothiazole conjugate their applicability in live cell imaging and use of the resultant complex as a Secondary Sensor of cn
Dalton Transactions, 2015Co-Authors: Nilesh Khairnar, Narinder Singh, Kundan Tayade, Suban K. Sahoo, Banashree Bondhopadhyay, Anupam Basu, Jasminder Singh, Vikas V. Gite, Anil KuwarAbstract:A benzothiazole derivative linked “off-on” multi-responsive and selective chemoSensor 3 has been synthesized and evaluated for cation recognition properties. The receptor 3 shows a high sensitivity and selectivity for Zn2+ through a ‘turn-on’ fluorescence response over the other tested cations with a detection limit as low as 0.67 μM. The receptor 3 was successfully applied for the detection of Zn2+ in live HeLa cells. Then, the Zn2+ complex of receptor 3 was also used for cyanide detection and recognition.
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A highly selective fluorescent ‘turn-on’ chemoSensor for Zn2+ based on a benzothiazole conjugate: their applicability in live cell imaging and use of the resultant complex as a Secondary Sensor of CN−
Dalton Transactions, 2015Co-Authors: Nilesh Khairnar, Narinder Singh, Kundan Tayade, Suban K. Sahoo, Banashree Bondhopadhyay, Anupam Basu, Jasminder Singh, Vikas V. Gite, Anil KuwarAbstract:A benzothiazole derivative linked “off-on” multi-responsive and selective chemoSensor 3 has been synthesized and evaluated for cation recognition properties. The receptor 3 shows a high sensitivity and selectivity for Zn2+ through a ‘turn-on’ fluorescence response over the other tested cations with a detection limit as low as 0.67 μM. The receptor 3 was successfully applied for the detection of Zn2+ in live HeLa cells. Then, the Zn2+ complex of receptor 3 was also used for cyanide detection and recognition.
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nanoaggregates of benzothiazole based amidine coupled chemoSensors a chemoSensor for ag and the resultant complex as a Secondary Sensor for cl
RSC Advances, 2014Co-Authors: Tilak Raj, Preeti Saluja, Narinder Singh, Doo Ok JangAbstract:Nanoaggregates of benzothiazole-based amidines were prepared for study as Sensors in aqueous medium. Sensor N2 was found to behave as a selective primary Sensor for Ag+, and the subsequent complex N2·Ag+ acted as a Secondary Sensor for Cl− in aqueous medium through a cation displacement mechanism. The cation displacement mechanism was further supported by a CV titration of complex N2·Ag+ with Cl−.
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Nanoaggregates of benzothiazole-based amidine-coupled chemoSensors: a chemoSensor for Ag+ and the resultant complex as a Secondary Sensor for Cl−
RSC Advances, 2014Co-Authors: Tilak Raj, Preeti Saluja, Narinder Singh, Doo Ok JangAbstract:Nanoaggregates of benzothiazole-based amidines were prepared for study as Sensors in aqueous medium. Sensor N2 was found to behave as a selective primary Sensor for Ag+, and the subsequent complex N2·Ag+ acted as a Secondary Sensor for Cl− in aqueous medium through a cation displacement mechanism. The cation displacement mechanism was further supported by a CV titration of complex N2·Ag+ with Cl−.
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Fluorescent primary Sensor for zinc and resultant complex as Secondary Sensor towards phosphorylated biomolecules: INHIBIT logic gate
Inorganica Chimica Acta, 2013Co-Authors: Kamalpreet Kaur, Vimal K. Bhardwaj, Navneet Kaur, Narinder SinghAbstract:Abstract Imine linked “on–off” multi-responsive and selective chemoSensor has been synthesized and evaluated for cation recognition properties. The receptor shows high sensitivity and selectivity for Zn 2+ through changes in fluorescence intensity based on ESIPT and charge transfer (CT) mechanism. The Zn 2+ complex of the receptor can be used for phosphate quantification and for recognition of phosphorylated biomolecules through cation displacement approach.
Pabitra Chattopadhyay - One of the best experts on this subject based on the ideXlab platform.
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a rhodamine based turn on al3 ion selective reporter and the resultant complex as a Secondary Sensor for f ion are applicable to living cell staining
Dalton Transactions, 2015Co-Authors: Buddhadeb Sen, Manjira Mukherjee, Samya Banerjee, Siddhartha Pal, Pabitra ChattopadhyayAbstract:A newly designed fluorescent aluminum(III) complex (L′–Al; 2) of a structurally characterized non-fluorescent rhodamine Schiff base (L) has been isolated in pure form and characterized using spectroscopic and physico-chemical methods with theoretical density functional theory (DFT) support. On addition of Al(III) ions to a solution of L in HEPES buffer (1 mM, pH 7.4; EtOH–water, 1:3 v/v) at 25 °C, the systematic increase in chelation-enhanced fluorescence (CHEF) enables the detection of Al(III) ions as low as 60 nM with high selectivity, unaffected by the presence of competitive ions. Interestingly, the Al(III) complex (L′–Al; 2) is specifically able to detect fluoride ions by quenching the fluorescence in the presence of large amounts of other anions in the HEPES buffer (1 mM, pH 7.4) at 25 °C. On the basis of our experimental and theoretical findings, the addition of Al3+ ions to a solution of L helps to generate a new fluorescence peak at 590 nm, due to the selective binding of Al3+ ions with L in a 1:1 ratio with a binding constant (K) of 8.13 × 104 M−1. The Schiff base L shows no cytotoxic effect, and it can therefore be employed for determining the intracellular concentration of Al3+ and F− ions by 2 in living cells using fluorescence microscopy.
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A rhodamine-based ‘turn-on’ Al3+ ion-selective reporter and the resultant complex as a Secondary Sensor for F− ion are applicable to living cell staining
Dalton Transactions, 2015Co-Authors: Buddhadeb Sen, Manjira Mukherjee, Samya Banerjee, Siddhartha Pal, Pabitra ChattopadhyayAbstract:A newly designed fluorescent aluminum(III) complex (L′–Al; 2) of a structurally characterized non-fluorescent rhodamine Schiff base (L) has been isolated in pure form and characterized using spectroscopic and physico-chemical methods with theoretical density functional theory (DFT) support. On addition of Al(III) ions to a solution of L in HEPES buffer (1 mM, pH 7.4; EtOH–water, 1:3 v/v) at 25 °C, the systematic increase in chelation-enhanced fluorescence (CHEF) enables the detection of Al(III) ions as low as 60 nM with high selectivity, unaffected by the presence of competitive ions. Interestingly, the Al(III) complex (L′–Al; 2) is specifically able to detect fluoride ions by quenching the fluorescence in the presence of large amounts of other anions in the HEPES buffer (1 mM, pH 7.4) at 25 °C. On the basis of our experimental and theoretical findings, the addition of Al3+ ions to a solution of L helps to generate a new fluorescence peak at 590 nm, due to the selective binding of Al3+ ions with L in a 1:1 ratio with a binding constant (K) of 8.13 × 104 M−1. The Schiff base L shows no cytotoxic effect, and it can therefore be employed for determining the intracellular concentration of Al3+ and F− ions by 2 in living cells using fluorescence microscopy.