The Experts below are selected from a list of 324 Experts worldwide ranked by ideXlab platform

S Subramanian - One of the best experts on this subject based on the ideXlab platform.

  • effect of eugenia jambolana Seed Kernel on antioxidant defense system in streptozotocin induced diabetes in rats
    Life Sciences, 2004
    Co-Authors: Kasiappan Ravi, Balasubramanian Ramachandran, S Subramanian
    Abstract:

    Increased oxidative stress has been suggested to be involved in the pathogenesis and progression of diabetic tissue damage. The aim of this study was to investigate the effect of ethanolic extract of Eugenia jambolana Seed Kernel on antioxidant defense systems of plasma and pancreas in streptozotocin-induced diabetes in rats. The levels of glucose, vitamin-C, vitamin-E, ceruloplasmin, reduced glutathione and lipidperoxides were estimated in plasma of control and experimental groups of rats. The levels of lipidperoxides, reduced glutathione and activities of superoxide dismutase, catalase and glutathione peroxidase were assayed in pancreatic tissue of control and experimental groups of rats. A significant increase in the levels of plasma glucose, vitamin-E, ceruloplasmin, lipid peroxides and a concomitant decrease in the levels of vitamin-C, reduced glutathione were observed in diabetic rats. The activities of pancreatic antioxidant enzymes were altered in diabetic rats. These alterations were reverted back to near normal level after the treatment with Eugenia jambolana Seed Kernel and glibenclamide. Histopathological studies also revealed that the protective effect of Eugenia jambolana Seed Kernel on pancreatic β-cells. The present study shows that Eugenia jambolana Seed Kernel decreased oxidative stress in diabetic rats, which inturn may be due to its hypoglycemic property.

  • protective effect of eugenia jambolana Seed Kernel on tissue antioxidants in streptozotocin induced diabetic rats
    Biological & Pharmaceutical Bulletin, 2004
    Co-Authors: Kasi Ravi, Balasubramanian Ramachandran, S Subramanian
    Abstract:

    Oxidative stress plays an important role in chronic complications of diabetes. In the present study the antioxidant effect of oral administration of ethanolic extract of Eugenia jambolana Seed Kernel on tissue antioxidant enzymes and lipid peroxidation in liver and kidney of streptozotocin-induced diabetic rats was evaluated. Administration of Seed Kernel to diabetic rats significantly decreased the levels of blood glucose, glycosylated hemoglobin and increased body weight gain, plasma insulin and hemoglobin. The diabetic rats showed the low activities of superoxide dismutase, catalase, glutathione peroxidase and reduced glutathione content in liver and kidney, which were restored to near normal levels by treatment with the Seed Kernel extract. The increased levels of lipid peroxidation and hydroperoxides in diabetic rats were reverted back to near normal levels after the treatment with Seed Kernel extract. Diabetic rats treated with Seed Kernel extract restored almost normal architecture of liver and kidney and were confirmed by histopathological examination. The present study reveals the efficacy of Eugenia jambolana Seed Kernel in the amelioration of diabetes, which may be attributed to its hypoglycemic property along with its antioxidant potential. The antioxidant effect of Eugenia jambolana Seed Kernel was also compared with glibenclamide, a standard hypoglycemic drug.

Marieke E Bruins - One of the best experts on this subject based on the ideXlab platform.

  • biorefinery methods for separation of protein and oil fractions from rubber Seed Kernel
    Industrial Crops and Products, 2014
    Co-Authors: Enny Ratnaningsih, Johan P M Sanders, Marieke E Bruins
    Abstract:

    Biorefinery of rubber Seeds can generate additional income for farmers, who already grow rubber trees for latex production. The aim of this study was to find the best method for protein and oil production from rubber Seed Kernel, with focus on protein recovery. Different pre-treatments and oil separation methods were tested, and alkaline conditions were used to extract protein. Next to processes with subsequent oil and protein recovery, a one-step combined oil and protein extraction was tested. Our study showed that oil separation is not necessary to obtain high protein recovery, however most of the extracted oil is present as an emulsion. The origin of the Seeds and their treatment on the plantation before processing were most important for high oil and protein recoveries, and in all cases tested had more influence on recoveries than its subsequent method of processing. Pressing the rubber Seed Kernel to separate the oil fraction followed by protein extraction from the press cake gives the highest protein recovery with satisfactory recovery for oil.

Kasiappan Ravi - One of the best experts on this subject based on the ideXlab platform.

  • effect of eugenia jambolana Seed Kernel on antioxidant defense system in streptozotocin induced diabetes in rats
    Life Sciences, 2004
    Co-Authors: Kasiappan Ravi, Balasubramanian Ramachandran, S Subramanian
    Abstract:

    Increased oxidative stress has been suggested to be involved in the pathogenesis and progression of diabetic tissue damage. The aim of this study was to investigate the effect of ethanolic extract of Eugenia jambolana Seed Kernel on antioxidant defense systems of plasma and pancreas in streptozotocin-induced diabetes in rats. The levels of glucose, vitamin-C, vitamin-E, ceruloplasmin, reduced glutathione and lipidperoxides were estimated in plasma of control and experimental groups of rats. The levels of lipidperoxides, reduced glutathione and activities of superoxide dismutase, catalase and glutathione peroxidase were assayed in pancreatic tissue of control and experimental groups of rats. A significant increase in the levels of plasma glucose, vitamin-E, ceruloplasmin, lipid peroxides and a concomitant decrease in the levels of vitamin-C, reduced glutathione were observed in diabetic rats. The activities of pancreatic antioxidant enzymes were altered in diabetic rats. These alterations were reverted back to near normal level after the treatment with Eugenia jambolana Seed Kernel and glibenclamide. Histopathological studies also revealed that the protective effect of Eugenia jambolana Seed Kernel on pancreatic β-cells. The present study shows that Eugenia jambolana Seed Kernel decreased oxidative stress in diabetic rats, which inturn may be due to its hypoglycemic property.

Balasubramanian Ramachandran - One of the best experts on this subject based on the ideXlab platform.

  • effect of eugenia jambolana Seed Kernel on antioxidant defense system in streptozotocin induced diabetes in rats
    Life Sciences, 2004
    Co-Authors: Kasiappan Ravi, Balasubramanian Ramachandran, S Subramanian
    Abstract:

    Increased oxidative stress has been suggested to be involved in the pathogenesis and progression of diabetic tissue damage. The aim of this study was to investigate the effect of ethanolic extract of Eugenia jambolana Seed Kernel on antioxidant defense systems of plasma and pancreas in streptozotocin-induced diabetes in rats. The levels of glucose, vitamin-C, vitamin-E, ceruloplasmin, reduced glutathione and lipidperoxides were estimated in plasma of control and experimental groups of rats. The levels of lipidperoxides, reduced glutathione and activities of superoxide dismutase, catalase and glutathione peroxidase were assayed in pancreatic tissue of control and experimental groups of rats. A significant increase in the levels of plasma glucose, vitamin-E, ceruloplasmin, lipid peroxides and a concomitant decrease in the levels of vitamin-C, reduced glutathione were observed in diabetic rats. The activities of pancreatic antioxidant enzymes were altered in diabetic rats. These alterations were reverted back to near normal level after the treatment with Eugenia jambolana Seed Kernel and glibenclamide. Histopathological studies also revealed that the protective effect of Eugenia jambolana Seed Kernel on pancreatic β-cells. The present study shows that Eugenia jambolana Seed Kernel decreased oxidative stress in diabetic rats, which inturn may be due to its hypoglycemic property.

  • protective effect of eugenia jambolana Seed Kernel on tissue antioxidants in streptozotocin induced diabetic rats
    Biological & Pharmaceutical Bulletin, 2004
    Co-Authors: Kasi Ravi, Balasubramanian Ramachandran, S Subramanian
    Abstract:

    Oxidative stress plays an important role in chronic complications of diabetes. In the present study the antioxidant effect of oral administration of ethanolic extract of Eugenia jambolana Seed Kernel on tissue antioxidant enzymes and lipid peroxidation in liver and kidney of streptozotocin-induced diabetic rats was evaluated. Administration of Seed Kernel to diabetic rats significantly decreased the levels of blood glucose, glycosylated hemoglobin and increased body weight gain, plasma insulin and hemoglobin. The diabetic rats showed the low activities of superoxide dismutase, catalase, glutathione peroxidase and reduced glutathione content in liver and kidney, which were restored to near normal levels by treatment with the Seed Kernel extract. The increased levels of lipid peroxidation and hydroperoxides in diabetic rats were reverted back to near normal levels after the treatment with Seed Kernel extract. Diabetic rats treated with Seed Kernel extract restored almost normal architecture of liver and kidney and were confirmed by histopathological examination. The present study reveals the efficacy of Eugenia jambolana Seed Kernel in the amelioration of diabetes, which may be attributed to its hypoglycemic property along with its antioxidant potential. The antioxidant effect of Eugenia jambolana Seed Kernel was also compared with glibenclamide, a standard hypoglycemic drug.

Enny Ratnaningsih - One of the best experts on this subject based on the ideXlab platform.

  • biorefinery methods for separation of protein and oil fractions from rubber Seed Kernel
    Industrial Crops and Products, 2014
    Co-Authors: Enny Ratnaningsih, Johan P M Sanders, Marieke E Bruins
    Abstract:

    Biorefinery of rubber Seeds can generate additional income for farmers, who already grow rubber trees for latex production. The aim of this study was to find the best method for protein and oil production from rubber Seed Kernel, with focus on protein recovery. Different pre-treatments and oil separation methods were tested, and alkaline conditions were used to extract protein. Next to processes with subsequent oil and protein recovery, a one-step combined oil and protein extraction was tested. Our study showed that oil separation is not necessary to obtain high protein recovery, however most of the extracted oil is present as an emulsion. The origin of the Seeds and their treatment on the plantation before processing were most important for high oil and protein recoveries, and in all cases tested had more influence on recoveries than its subsequent method of processing. Pressing the rubber Seed Kernel to separate the oil fraction followed by protein extraction from the press cake gives the highest protein recovery with satisfactory recovery for oil.