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Jeong-hee Kim - One of the best experts on this subject based on the ideXlab platform.

  • relationship of Self Transcendence traits with in vivo dopamine d2 3 receptor availability and functional connectivity an 18 f fallypride pet and fmri study
    Synapse, 2019
    Co-Authors: Paul Cumming, Jeong-hee Kim, Yi Seul Choe, Young-don Son, Hang-keun Kim, Yo Han Joo, Jong-hoon Kim
    Abstract:

    Genetic research has implicated dopamine neurotransmission in the expression of the Self-Transcendence trait in humans. However, molecular imaging of dopaminergic markers is undocumented in relation to this personality trait. In this multimodal imaging study, we first investigated the relationship between the Self-Transcendence trait and in vivo dopamine D2/3 receptor availability using [18 F]fallypride positron emission tomography (PET). We next conducted seed-based functional connectivity analyses using resting-state functional magnetic resonance imaging (rs-fMRI) data with regions derived from the PET analysis as seeds to explore the functional significance of D2/3 receptor availability foci associated with the Self-Transcendence trait. Twenty-one healthy subjects underwent high-resolution PET with [18 F]fallypride and a subset of 18 subjects also completed 3-Tesla rs-fMRI. The Temperament and Character Inventory was used to measure the Self-Transcendence trait. A voxel-based whole brain analysis revealed that the [18 F]fallypride binding potential (BPND ) within the cluster of the left insula was significantly positively correlated with Self-Transcendence trait scores. A region-of-interest analysis also showed a significant positive correlation between Self-Transcendence and [18 F]fallypride BPND in the left insula. The exploratory [18 F]fallypride BPND seed-based rs-fMRI analysis showed that the functional connectivity from the left insula seed to the prefrontal cortices (including the inferior frontal region) was negatively associated with Self-Transcendence trait scores. The results of the present study suggest that D2/3 receptor-mediated neurotransmission in the left insula may constitute a significant neurobiological factor in the Self-Transcendence trait. The negative associations between BPND seed-based functional connectivity and Self-Transcendence trait scores may suggest reduced prefrontal control in this personality trait.

Jong-hoon Kim - One of the best experts on this subject based on the ideXlab platform.

  • relationship of Self Transcendence traits with in vivo dopamine d2 3 receptor availability and functional connectivity an 18 f fallypride pet and fmri study
    Synapse, 2019
    Co-Authors: Paul Cumming, Jeong-hee Kim, Yi Seul Choe, Young-don Son, Hang-keun Kim, Yo Han Joo, Jong-hoon Kim
    Abstract:

    Genetic research has implicated dopamine neurotransmission in the expression of the Self-Transcendence trait in humans. However, molecular imaging of dopaminergic markers is undocumented in relation to this personality trait. In this multimodal imaging study, we first investigated the relationship between the Self-Transcendence trait and in vivo dopamine D2/3 receptor availability using [18 F]fallypride positron emission tomography (PET). We next conducted seed-based functional connectivity analyses using resting-state functional magnetic resonance imaging (rs-fMRI) data with regions derived from the PET analysis as seeds to explore the functional significance of D2/3 receptor availability foci associated with the Self-Transcendence trait. Twenty-one healthy subjects underwent high-resolution PET with [18 F]fallypride and a subset of 18 subjects also completed 3-Tesla rs-fMRI. The Temperament and Character Inventory was used to measure the Self-Transcendence trait. A voxel-based whole brain analysis revealed that the [18 F]fallypride binding potential (BPND ) within the cluster of the left insula was significantly positively correlated with Self-Transcendence trait scores. A region-of-interest analysis also showed a significant positive correlation between Self-Transcendence and [18 F]fallypride BPND in the left insula. The exploratory [18 F]fallypride BPND seed-based rs-fMRI analysis showed that the functional connectivity from the left insula seed to the prefrontal cortices (including the inferior frontal region) was negatively associated with Self-Transcendence trait scores. The results of the present study suggest that D2/3 receptor-mediated neurotransmission in the left insula may constitute a significant neurobiological factor in the Self-Transcendence trait. The negative associations between BPND seed-based functional connectivity and Self-Transcendence trait scores may suggest reduced prefrontal control in this personality trait.

Paul Cumming - One of the best experts on this subject based on the ideXlab platform.

  • relationship of Self Transcendence traits with in vivo dopamine d2 3 receptor availability and functional connectivity an 18 f fallypride pet and fmri study
    Synapse, 2019
    Co-Authors: Paul Cumming, Jeong-hee Kim, Yi Seul Choe, Young-don Son, Hang-keun Kim, Yo Han Joo, Jong-hoon Kim
    Abstract:

    Genetic research has implicated dopamine neurotransmission in the expression of the Self-Transcendence trait in humans. However, molecular imaging of dopaminergic markers is undocumented in relation to this personality trait. In this multimodal imaging study, we first investigated the relationship between the Self-Transcendence trait and in vivo dopamine D2/3 receptor availability using [18 F]fallypride positron emission tomography (PET). We next conducted seed-based functional connectivity analyses using resting-state functional magnetic resonance imaging (rs-fMRI) data with regions derived from the PET analysis as seeds to explore the functional significance of D2/3 receptor availability foci associated with the Self-Transcendence trait. Twenty-one healthy subjects underwent high-resolution PET with [18 F]fallypride and a subset of 18 subjects also completed 3-Tesla rs-fMRI. The Temperament and Character Inventory was used to measure the Self-Transcendence trait. A voxel-based whole brain analysis revealed that the [18 F]fallypride binding potential (BPND ) within the cluster of the left insula was significantly positively correlated with Self-Transcendence trait scores. A region-of-interest analysis also showed a significant positive correlation between Self-Transcendence and [18 F]fallypride BPND in the left insula. The exploratory [18 F]fallypride BPND seed-based rs-fMRI analysis showed that the functional connectivity from the left insula seed to the prefrontal cortices (including the inferior frontal region) was negatively associated with Self-Transcendence trait scores. The results of the present study suggest that D2/3 receptor-mediated neurotransmission in the left insula may constitute a significant neurobiological factor in the Self-Transcendence trait. The negative associations between BPND seed-based functional connectivity and Self-Transcendence trait scores may suggest reduced prefrontal control in this personality trait.

Romualdas Juknys - One of the best experts on this subject based on the ideXlab platform.

  • the role of values environmental risk perception awareness of consequences and willingness to assume responsibility for environmentally friendly behaviour the lithuanian case
    Journal of Cleaner Production, 2016
    Co-Authors: Genovaitė Liobikienė, Romualdas Juknys
    Abstract:

    Abstract In this study, the value-belief-norm theory was applied. Analysing the impact of values on environmentally-friendly behaviour, goal framing theory was taken into consideration. According to the Lithuanian representative survey conducted in 2011 and using factor analysis, two different value orientations were identified: Self-Transcendence and Self-enhancement. The results showed that people with stronger Self-Transcendence value orientation, which are guided by normative goals, are more perceptive of environmental problems and are more inclined to assume responsibility and behave in a more environmentally-friendly way. After applying the regression analysis to the data, it was found that the most important direct determinants of environmental behaviour were Self-Transcendence value orientation, environmental problem perception, and the assumption of responsibility. However, a gap between awareness of behavioural consequences and real behaviour was observed. These findings could be important for policy implications when seeking to promote behaviour that is more environmentally-friendly.

Genovaitė Liobikienė - One of the best experts on this subject based on the ideXlab platform.

  • the role of values environmental risk perception awareness of consequences and willingness to assume responsibility for environmentally friendly behaviour the lithuanian case
    Journal of Cleaner Production, 2016
    Co-Authors: Genovaitė Liobikienė, Romualdas Juknys
    Abstract:

    Abstract In this study, the value-belief-norm theory was applied. Analysing the impact of values on environmentally-friendly behaviour, goal framing theory was taken into consideration. According to the Lithuanian representative survey conducted in 2011 and using factor analysis, two different value orientations were identified: Self-Transcendence and Self-enhancement. The results showed that people with stronger Self-Transcendence value orientation, which are guided by normative goals, are more perceptive of environmental problems and are more inclined to assume responsibility and behave in a more environmentally-friendly way. After applying the regression analysis to the data, it was found that the most important direct determinants of environmental behaviour were Self-Transcendence value orientation, environmental problem perception, and the assumption of responsibility. However, a gap between awareness of behavioural consequences and real behaviour was observed. These findings could be important for policy implications when seeking to promote behaviour that is more environmentally-friendly.