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Guy Vallancien - One of the best experts on this subject based on the ideXlab platform.
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prognostic significance of Seminal Vesicle invasion on the radical prostatectomy specimen
European Urology, 1998Co-Authors: Bertrand Debras, Bertrand Guillonneau, Joelle Bougaran, Emmanuel Chambon, Guy VallancienAbstract:Objective: The prognostic significance of Seminal Vesicle invasion on the radical prostatectomy specimen was evaluated according to the proximal or distal site of this invasion. <
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indications for preoperative Seminal Vesicle biopsies in staging of clinically localized prostatic cancer
European Urology, 1997Co-Authors: Bertrand Guillonneau, Bertrand Debras, Bruno Veillon, Joelle Bougaran, Emmanuel Chambon, Guy VallancienAbstract:OBJECTIVE: To identify patients at high risk of extraprostatic Seminal Vesicle infiltration, in whom preoperative Seminal Vesicle biopsies should be performed. MATERIALS AND METHODS: We studied the relationship between extraprostatic Seminal Vesicle infiltration and the available preoperative data [age, clinical stage, prostate-specific antigen (PSA) level, number and site of positive prostatic sextant biopsies, Gleason score] in a total of 75 patients suffering from clinically localized prostatic adenocarcinoma who were candidates for radical prostatectomy. RESULTS: The chi 2 test showed that the preoperative data most significantly correlated with extraprostatic Seminal Vesicle infiltration were the presence of positive basal biopsies (p < 0.001). The PSA level did not have any predictive value. The most discriminant preoperative parameter of the state of the Seminal Vesicles (analysis of variance on a univariate model) was the state of the basal prostatic biopsies. The importance of this parameter was confirmed by cluster analysis. Overall, the risk of extraprostatic Seminal Vesicle invasion was 0 (0/21 patients) when the 2 basal prostatic biopsies were negative, 10.25% (4/39 patients) when 1 of the 2 basal prostatic biopsies was positive and 73.33% (11/15 patients) when both basal prostatic biopsies were positive. CONCLUSIONS: In a patient with clinically localized prostatic adenocarcinoma who is a candidate for radical prostatectomy, Seminal Vesicle biopsies are useless when basal prostatic biopsies are negative, regardless of the state of other preoperative parameters. When 1 or 2 basal prostatic biopsies are positive, Seminal Vesicle biopsies can improve the pretreatment pathological staging.
Thomas A. Stamey - One of the best experts on this subject based on the ideXlab platform.
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Efficacy of transrectal ultrasound-guided Seminal Vesicle biopsies in the detection of Seminal Vesicle invasion by prostate cancer.
The Journal of Urology, 1993Co-Authors: Martha K. Terris, John E. Mcneal, Fuad S. Freiha, Thomas A. StameyAbstract:AbstractDetection of microscopic Seminal Vesicle invasion with prostate cancer by transrectal ultrasound-guided Seminal Vesicle biopsies provides a method of evaluation that is much less subjective than digital rectal examination or imaging techniques. The accuracy of Seminal Vesicle biopsy is analyzed in 73 patients undergoing transrectal ultrasound-guided biopsy of 145 Seminal Vesicles followed by radical prostatectomy.Of 133 benign Seminal Vesicle biopsies 11 (8.3%) were found in the surgical specimen to have cancer involving an average of 6% of the Seminal Vesicle area. Of 8 Seminal Vesicle biopsies showing cancer adjacent to Seminal Vesicle epithelium 100% demonstrated Seminal Vesicle invasion in the surgical specimen extending for an average of 19% of the Seminal Vesicle area. Three biopsies exhibited cancer but no Seminal Vesicle epithelium; only 1 (33%) of these had Seminal Vesicle invasion for 5% of the Seminal Vesicle area. One biopsy revealed normal prostate tissue. Careful placement of bilater...
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pathogenesis and biological significance of Seminal Vesicle invasion in prostatic adenocarcinoma
The Journal of Urology, 1990Co-Authors: Arnauld Villers, John E. Mcneal, Fuad S. Freiha, Elise A Redwine, Thomas A. StameyAbstract:AbstractSeminal Vesicle invasion and the percentage involvement by cancer of each Seminal Vesicle were related to cancer volume, quantitative histological grade and presence or absence of lymph node metastases in 243 radical prostatectomy specimens. There were 47 prostates with Seminal Vesicle invasion. Frequency and extent of Seminal Vesicle invasion were strongly correlated with cancer volume, with minimal invasion noted in only 6% of the cases less than 4 cc. The relationship of Seminal Vesicle invasion to lymph node metastasis was statistically significant but cancer volume and histological grade were much stronger predictors of lymph node metastasis. The route of invasion from the prostate in 46 cases involved direct tumor spread into the midbase region near the ejaculatory ducts. Seminal Vesicle invasion often may not be identified if the tissue nearest the ejaculatory ducts at the prostate base is not sampled.
Kyung Chul Moon - One of the best experts on this subject based on the ideXlab platform.
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squamous cell carcinoma of the Seminal Vesicle from zinner syndrome a case report and review of literature
Journal of pathology and translational medicine, 2015Co-Authors: Hae Woon Baek, Eunoh Choi, Kyung Chul MoonAbstract:Until now, fewer than 60 cases of tumors originating from the Seminal Vesicle have been reported. Most of them were adenocarcinoma, cystadenoma, and benign mesenchymal tumor [1]. Among them, only three cases in the English literature have been reported as squamous cell carcinoma [2-4]. Although all three cases had a prolonged history of stone formation or chronic inflammation, none of them were associated with congenital malformation of the urogenital system such as Zinner syndrome. Zinner syndrome is a rare Mullerian duct abnormality consisting of unilateral renal agenesis, ipsilateral Seminal Vesicle cyst, and ejaculatory duct obstruction. Herein, we report a 41-year-old male with Zinner syndrome, who developed a poorly differentiated squamous cell carcinoma of the Seminal Vesicle as a result of prolonged inflammation.
Jonathan P. Jarow - One of the best experts on this subject based on the ideXlab platform.
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Seminal Vesicle Aspiration of Fertile Men
The Journal of Urology, 1996Co-Authors: Jonathan P. JarowAbstract:AbstractPurpose: Whether sperm normally reside in the Seminal Vesicles of fertile men without ejaculatory duct obstruction, and the effect of duration of sexual abstinence on results of Seminal Vesicle aspiration were determined.Materials and Methods: Bilateral Seminal Vesicle aspiration was performed on 12 fertile volunteers under transrectal ultrasound guidance with randomization according to 0 and 5 days of abstinence. Seminal Vesicle were examined microscopically for number and motility of sperm. A positive aspirate was defined as greater than 3 sperm per high power microscopic field.Results: Duration of abstinence had a significant effect on outcome of Seminal Vesicle aspiration in fertile volunteers. No volunteer with 0 days of abstinence had a positive aspirate from either Seminal Vesicle, whereas a third of those with 5 days of abstinence had at least 1 positive Seminal Vesicle aspirate.Conclusions: Significant numbers of sperm are not normally found in the Seminal Vesicles of fertile men immediat...
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Seminal Vesicle aspiration in the management of patients with ejaculatory duct obstruction
The Journal of Urology, 1994Co-Authors: Jonathan P. JarowAbstract:AbstractEjaculatory duct obstruction is a rare but significant cause of male factor infertility. Vasography is the current gold standard for the diagnosis of complete obstruction of the ejaculatory ducts. However, there is currently no reliable method to diagnose partial obstruction. We performed Seminal Vesicle aspiration under transrectal ultrasonographic guidance in 11 infertile men to assess the use of this diagnostic test in the evaluation and management of patients with ejaculatory duct obstruction. The absence of sperm within the Seminal Vesicle aspirate from 8 patients who had sperm in the ejaculate demonstrates that sperm are not normally present within the Seminal Vesicles. Numerous motile sperm were observed in the Seminal Vesicle aspirate from an azoospermic patient in whom vasography documented complete ejaculatory duct obstruction, demonstrating that sperm can reflux into the Seminal Vesicles in patients with distal obstruction. Two patients with suspected partial ejaculatory duct obstructio...
Bertrand Guillonneau - One of the best experts on this subject based on the ideXlab platform.
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prognostic significance of Seminal Vesicle invasion on the radical prostatectomy specimen
European Urology, 1998Co-Authors: Bertrand Debras, Bertrand Guillonneau, Joelle Bougaran, Emmanuel Chambon, Guy VallancienAbstract:Objective: The prognostic significance of Seminal Vesicle invasion on the radical prostatectomy specimen was evaluated according to the proximal or distal site of this invasion. <
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indications for preoperative Seminal Vesicle biopsies in staging of clinically localized prostatic cancer
European Urology, 1997Co-Authors: Bertrand Guillonneau, Bertrand Debras, Bruno Veillon, Joelle Bougaran, Emmanuel Chambon, Guy VallancienAbstract:OBJECTIVE: To identify patients at high risk of extraprostatic Seminal Vesicle infiltration, in whom preoperative Seminal Vesicle biopsies should be performed. MATERIALS AND METHODS: We studied the relationship between extraprostatic Seminal Vesicle infiltration and the available preoperative data [age, clinical stage, prostate-specific antigen (PSA) level, number and site of positive prostatic sextant biopsies, Gleason score] in a total of 75 patients suffering from clinically localized prostatic adenocarcinoma who were candidates for radical prostatectomy. RESULTS: The chi 2 test showed that the preoperative data most significantly correlated with extraprostatic Seminal Vesicle infiltration were the presence of positive basal biopsies (p < 0.001). The PSA level did not have any predictive value. The most discriminant preoperative parameter of the state of the Seminal Vesicles (analysis of variance on a univariate model) was the state of the basal prostatic biopsies. The importance of this parameter was confirmed by cluster analysis. Overall, the risk of extraprostatic Seminal Vesicle invasion was 0 (0/21 patients) when the 2 basal prostatic biopsies were negative, 10.25% (4/39 patients) when 1 of the 2 basal prostatic biopsies was positive and 73.33% (11/15 patients) when both basal prostatic biopsies were positive. CONCLUSIONS: In a patient with clinically localized prostatic adenocarcinoma who is a candidate for radical prostatectomy, Seminal Vesicle biopsies are useless when basal prostatic biopsies are negative, regardless of the state of other preoperative parameters. When 1 or 2 basal prostatic biopsies are positive, Seminal Vesicle biopsies can improve the pretreatment pathological staging.
