The Experts below are selected from a list of 297 Experts worldwide ranked by ideXlab platform
Yin Ching Chuang - One of the best experts on this subject based on the ideXlab platform.
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prognostic factors and antibiotics in vibrio vulnificus Septicemia
JAMA Internal Medicine, 2006Co-Authors: Hung Jen Tang, Wen Chien Ko, Poren Hsueh, Yin Ching ChuangAbstract:Background:Immunocompromised patients withVibriovulnificusSepticemiaareathighriskforfatality.When ahemorrhagicbullousnecroticcutaneouslesion(HBNCL) anddecreasedbloodpressuredevelop,approximately50% of V vulnificus septicemic patients die within 48 hours. This study aimed to evaluate the risk factor(s) for fatality among patients with V vulnificus Septicemia, emphasizing the role of prescribed antimicrobial agents in general and the therapeutic efficacy of the combination of a third-generationcephalosporinandtetracyclineoritsanalogue in particular. Methods:Patients with the diagnosis ofV vulnificusinfectionadmitted to 5 large medical centers in Taiwan between 1995 and 2003 were included in this retrospectivestudy.Patientsweredividedinto2groups:thosewith HBNCLs and those without HBNCLs. Patients were further divided into subgoups without fatalities (fatal subgroup) and those without fatalities (nonfatal subgroup).
Arvind V Bhore - One of the best experts on this subject based on the ideXlab platform.
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bacteriological profile of neonatal Septicemia in a tertiary care hospital from western india
Journal of Global Infectious Diseases, 2015Co-Authors: Vrishali A Muley, Dnyaneshwari P Ghadage, Arvind V BhoreAbstract:Neonatal Septicemia is an important cause of morbidity and mortality. The present study was undertaken to determine the bacteriological profile and antimicrobial susceptibility pattern of prevalent pathogens isolated from the blood of septicemic neonates from Neonatal Intensive Care Unit (NICU). A total of 180 blood samples of septicemic neonates were studied bacteriologically. Antimicrobial susceptibility testing was done by the Kirby Bauer disc diffusion method in accordance to Clinical Laboratory Standards Institutes (CLSI) guidelines. 26.6% (48 out of 180) cases of Septicemia could be confirmed by blood culture. Of these, 66.7% cases were of early onset Septicemia (EOS) and 33.3% were of late onset Septicemia (LOS). Klebsiella pneumoniae was the predominant pathogen (35.4%) among the Gram-negative pathogens and Staphylococcus aureus (22.9%) was the predominant Gram-positive pathogen. 28% of K. pneumoniae and E. coli isolates were extended spectrum beta-lactamase (ESBL) producers. 18.1% of the Staphylococcus isolates were methicillin-resistant S. aureus (MRSA). Multi-drug-resistance pattern was observed with all the isolates. Ciprofloxacin and aminoglycosides were the most effective drugs against Gram-positive and Gram-negative isolates. This study highlights the predominance of Gram-negative organisms in causing neonatal sepsis and emergence of multi-drug-resistant strains in our set up.
A E Meinders - One of the best experts on this subject based on the ideXlab platform.
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purpura fulminans and symmetrical peripheral gangrene caused by capnocytophaga canimorsus formerly df 2 Septicemia a complication of dog bite
Medicine, 1991Co-Authors: B J Kullberg, R G Westendorp, A E MeindersAbstract:We review the syndrome of Capnocytophaga canimorsus (DF-2) Septicemia after exposure to dogs or cats. We describe a previously healthy patient who developed diffuse intravascular coagulation and symmetrical peripheral gangrene as a result of C. canimorsus Septicemia after a dog bite. To our knowledge, this patient was the first to receive combined plasmapheresis and leukapheresis for C. canimorsus Septicemia. Symmetrical peripheral gangrene is frequently associated with C. canimorsus Septicemia and may lead to an early diagnosis in patients who become severely ill after a dog bite. Other complications include arthritis, meningitis, and endocarditis. These manifestations can also be found in previously healthy patients, although a prior splenectomy or other causes of impaired host defense clearly enhance the risk. Prompt treatment with penicillin G is required.
Hari H Dayal - One of the best experts on this subject based on the ideXlab platform.
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chronic liver disease and consumption of raw oysters a potentially lethal combination a review of vibrio vulnificus Septicemia
The American Journal of Gastroenterology, 2005Co-Authors: Hari H DayalAbstract:Vibrio vulnificus Septicemia is the most common cause of fatality related to seafood consumption in the United States. It occurs predominantly in patients with chronic liver disease following consumption of raw oysters. V. vulnificus is a highly virulent human pathogen, normally found in warm estuarine and marine environment. It lodges in filter feeders like oysters. The onset of this illness is abrupt, rapidly progressing to septic shock with a high mortality. Clinicians managing patients with chronic liver disease need to educate their patients of the risk associated with the consumption of raw seafood, especially oysters. A high index of suspicion is necessary for appropriate treatments, as doxycycline, the antibiotic of choice, is not usually a part of the empiric therapy for Septicemia. The high mortality associated with this Septicemia demands aggressive preventive measures: susceptible individuals must be forewarned by signs displayed in restaurants; physicians must educate patients with chronic liver disease about the risk of raw oyster consumption; and harvesting methods which reduce contamination by V. vulnificus must be utilized.
Hung Jen Tang - One of the best experts on this subject based on the ideXlab platform.
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prognostic factors and antibiotics in vibrio vulnificus Septicemia
JAMA Internal Medicine, 2006Co-Authors: Hung Jen Tang, Wen Chien Ko, Poren Hsueh, Yin Ching ChuangAbstract:Background:Immunocompromised patients withVibriovulnificusSepticemiaareathighriskforfatality.When ahemorrhagicbullousnecroticcutaneouslesion(HBNCL) anddecreasedbloodpressuredevelop,approximately50% of V vulnificus septicemic patients die within 48 hours. This study aimed to evaluate the risk factor(s) for fatality among patients with V vulnificus Septicemia, emphasizing the role of prescribed antimicrobial agents in general and the therapeutic efficacy of the combination of a third-generationcephalosporinandtetracyclineoritsanalogue in particular. Methods:Patients with the diagnosis ofV vulnificusinfectionadmitted to 5 large medical centers in Taiwan between 1995 and 2003 were included in this retrospectivestudy.Patientsweredividedinto2groups:thosewith HBNCLs and those without HBNCLs. Patients were further divided into subgoups without fatalities (fatal subgroup) and those without fatalities (nonfatal subgroup).
