The Experts below are selected from a list of 258 Experts worldwide ranked by ideXlab platform
Şenol Sarisoy - One of the best experts on this subject based on the ideXlab platform.
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THE EFFECTS OF Serial Extraction ON THE SOFT-TISSUE PROFILE: (Seri Çekimin Yumuşak Doku Profiline Etkisi)
Turkish Journal of Orthodontics, 1998Co-Authors: Lale Sarisoy, Hakan N. Işcan, Şenol SarisoyAbstract:Ozet Seri cekimin premolar cekimi etkisine bagli olarak duz profillere yol actigi belirtilmistir. Buna karsilik premolar cekiminin fasial profilin istenmeyen duzlesmesine yol acmadigini belirten dusunceler de mevcuttur. Bu arastirma, seri cekimin fasial profil uzerine etkilerini belirlemek amaciyla yapilmistir. Angle Sinif / ve hafif Sinif 11,1 malokluzyona sahip vakalardan, seri cekim grubu 20, kontrol grubu ise 21 vaka icerecek sekilde olusturuldu. Bu gruplar, yas ve vertikal ve sagittal iskeletsel sefalometrik ozellikleri bakimindan eslestirildi. Seri cekim islemleri Dewel’e gore uygulanirken, kontrol grubu herhangibir ortodontik tedavi uygulanmaksizin 3-5 yil izlendi. Bu arastirmanin sonuclari, seri cekimin yumusak doku profiline olumsuz etkileri oldugu gorusunu desteklememektedir. Yumusak doku B noktasi ve dolayisiyla labiomental aci uzerindeki etkiler disinda seri cekimin yumusak doku profili uzerinde belirgin bir etkisine rastlanilmamistir.
Lale Sarisoy - One of the best experts on this subject based on the ideXlab platform.
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THE EFFECTS OF Serial Extraction ON THE SOFT-TISSUE PROFILE: (Seri Çekimin Yumuşak Doku Profiline Etkisi)
Turkish Journal of Orthodontics, 1998Co-Authors: Lale Sarisoy, Hakan N. Işcan, Şenol SarisoyAbstract:Ozet Seri cekimin premolar cekimi etkisine bagli olarak duz profillere yol actigi belirtilmistir. Buna karsilik premolar cekiminin fasial profilin istenmeyen duzlesmesine yol acmadigini belirten dusunceler de mevcuttur. Bu arastirma, seri cekimin fasial profil uzerine etkilerini belirlemek amaciyla yapilmistir. Angle Sinif / ve hafif Sinif 11,1 malokluzyona sahip vakalardan, seri cekim grubu 20, kontrol grubu ise 21 vaka icerecek sekilde olusturuldu. Bu gruplar, yas ve vertikal ve sagittal iskeletsel sefalometrik ozellikleri bakimindan eslestirildi. Seri cekim islemleri Dewel’e gore uygulanirken, kontrol grubu herhangibir ortodontik tedavi uygulanmaksizin 3-5 yil izlendi. Bu arastirmanin sonuclari, seri cekimin yumusak doku profiline olumsuz etkileri oldugu gorusunu desteklememektedir. Yumusak doku B noktasi ve dolayisiyla labiomental aci uzerindeki etkiler disinda seri cekimin yumusak doku profili uzerinde belirgin bir etkisine rastlanilmamistir.
Tobias Sjöblom - One of the best experts on this subject based on the ideXlab platform.
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Automated Serial Extraction of DNA and RNA from biobanked tissue specimens
BMC biotechnology, 2013Co-Authors: Lucy Mathot, Monica Wallin, Tobias SjöblomAbstract:Background With increasing biobanking of biological samples, methods for large scale Extraction of nucleic acids are in demand. The lack of such techniques designed for Extraction from tissues results in a bottleneck in downstream genetic analyses, particularly in the field of cancer research. We have developed an automated procedure for tissue homogenization and Extraction of DNA and RNA into separate fractions from the same frozen tissue specimen. A purpose developed magnetic bead based technology to Serially extract both DNA and RNA from tissues was automated on a Tecan Freedom Evo robotic workstation.
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Efficient and scalable Serial Extraction of DNA and RNA from frozen tissue samples
Chemical communications (Cambridge England), 2010Co-Authors: Lucy Mathot, Monica Lindman, Tobias SjöblomAbstract:Advances in cancer genomics have created a demand for scalable sample processing. We here present a process for Serial Extraction of nucleic acids from the same frozen tissue sample based on magnetic silica particles. The process is automation friendly with high recoveries of pure DNA and RNA suitable for analysis.
Jonathan E. Naile - One of the best experts on this subject based on the ideXlab platform.
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Decades-Scale Degradation of Commercial, Side-Chain, Fluorotelomer-Based Polymers in Soils and Water
Environmental science & technology, 2015Co-Authors: John W. Washington, Thomas M. Jenkins, Keegan Rankin, Jonathan E. NaileAbstract:Fluorotelomer-based polymers (FTPs) are the primary product of the fluorotelomer industry. Here we report on a 376-day study of the degradability of two commercial acrylate-linked FTPs in four saturated soils and in water. Using an exhaustive Serial Extraction, we report GC/MS and LC/MS/MS results for 50 species including fluorotelomer alcohols and acids, and perfluorocarboxylates. Modeling of seven sampling rounds, each consisting of ≥5 replicate microcosm treatments, for one commercial FTP in one soil yielded half-life estimates of 65–112 years and, when the other commercial FTP and soils were evaluated, the estimated half-lives ranged from 33 to 112 years. Experimental controls, consisting of commercial FTP in water, degraded roughly at the same rate as in soil. A follow-up experiment, with commercial FTP in pH 10 water, degraded roughly 10-fold faster than the circum-neutral control suggesting that commercial FTPs can undergo OH–-mediated hydrolysis. 8:2Fluorotelomer alcohol generated from FTP degradation in soil was more stable than without FTP present suggesting a clathrate guest–host association with the FTP. To our knowledge, these are the only degradability-test results for commercial FTPs that have been generated using exhaustive Extraction procedures. They unambiguously show that commercial FTPs, the primary product of the fluorotelomer industry, are a source of fluorotelomer and perfluorinated compounds to the environment.
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Decades-Scale Degradation of Commercial, Side-Chain, Fluorotelomer-Based Polymers in Soils and Water
2015Co-Authors: John W. Washington, Keegan Rankin, Thomas M. Jenkins, Jonathan E. NaileAbstract:Fluorotelomer-based polymers (FTPs) are the primary product of the fluorotelomer industry. Here we report on a 376-day study of the degradability of two commercial acrylate-linked FTPs in four saturated soils and in water. Using an exhaustive Serial Extraction, we report GC/MS and LC/MS/MS results for 50 species including fluorotelomer alcohols and acids, and perfluorocarboxylates. Modeling of seven sampling rounds, each consisting of ≥5 replicate microcosm treatments, for one commercial FTP in one soil yielded half-life estimates of 65–112 years and, when the other commercial FTP and soils were evaluated, the estimated half-lives ranged from 33 to 112 years. Experimental controls, consisting of commercial FTP in water, degraded roughly at the same rate as in soil. A follow-up experiment, with commercial FTP in pH 10 water, degraded roughly 10-fold faster than the circum-neutral control suggesting that commercial FTPs can undergo OH–-mediated hydrolysis. 8:2Fluorotelomer alcohol generated from FTP degradation in soil was more stable than without FTP present suggesting a clathrate guest–host association with the FTP. To our knowledge, these are the only degradability-test results for commercial FTPs that have been generated using exhaustive Extraction procedures. They unambiguously show that commercial FTPs, the primary product of the fluorotelomer industry, are a source of fluorotelomer and perfluorinated compounds to the environment
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Characterizing fluorotelomer and polyfluoroalkyl substances in new and aged fluorotelomer-based polymers for degradation studies with GC/MS and LC/MS/MS.
Environmental science & technology, 2014Co-Authors: John W. Washington, Thomas M. Jenkins, Jonathan E. Naile, David G. LynchAbstract:Fluorotelomer-based polymers (FTPs), the dominant product of the fluorotelomer industry, are antistaining and antiwetting agents that permeate the products and surfaces of modern society. However, the degree to which these materials expose humans and the environment to fluorotelomer and perfluorinated compounds, including recalcitrant and toxic compounds such as perfluorooctanoic acid (PFOA), is ill-defined. The design intent of FTPs, to minimize interaction with other substances, including solvents, heretofore has stymied efforts to develop robust methods to characterize the content of monomers and associated compounds of new commercial FTPs, as well as commercial FTPs that have been aged in environmental media for degradation testing. Here we show that FTPs can be exhausted of these compounds and quantitated by (i) drying the FTP on a suitable substrate at elevated temperature to achieve low, constant monomer concentrations; (ii) Serial Extraction with MTBE for fluorotelomer-monomer analysis by GC/MS in...
Mayte Buchbender - One of the best experts on this subject based on the ideXlab platform.
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management of anticoagulated patients in dentoalveolar surgery a clinical comparative study
Clinical Oral Investigations, 2020Co-Authors: Christian Schmitt, R Clemm, B Rusche, Fw Neukam, Mayte BuchbenderAbstract:OBJECTIVES This prospective, comparative, clinical study analyzed the postoperative bleeding risk of patients on anticoagulation therapy (AT) who were undergoing tooth Extractions and osteotomies. MATERIALS AND METHODS Patients with the following ATs were included (test groups): (1.) platelet aggregation inhibitors (PAIs), (2.) vitamin K inhibitors, (3.) low molecular weight heparin (LMWH), and (4.) direct oral anticoagulants (DOACs). Patients in the control group were not on any AT (non-AT group). Patients were subdivided into the following treatment groups: (1.) single tooth Extraction, (2.) Serial Extraction (≥ 2 adjacent teeth), and (3.) tooth osteotomy. Pre-, intra-, and postoperative data concerning the treatment, extent of the surgery, and bleeding were recorded and statistically evaluated. RESULTS There were 15 postoperative bleeding events in 838 patients (1.7%): four (0.7%) in the non-AT group (n = 603 patients) and 11 (4.7%) in the AT group (n = 235 patients). The surgical procedure had no statistically significant effect on postoperative bleeding frequencies. Patients taking vitamin K inhibitors had a significantly higher risk of postoperative bleeding compared with patients without AT (p < 0.00001). Four patients were hospitalized due to the severity of the bleeding (vitamin K inhibitor group). Postoperative bleeding events were all controlled with local hemostatic measures. CONCLUSIONS The postoperative bleeding risk after tooth Extractions and osteotomies in patients continuing AT is low, and bleeding can be controlled with local hemostatic measures. CLINICAL RELEVANCE AT should be continued in patients undergoing tooth removal procedures under the provision that local hemostatic measures are applied.
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Management of anticoagulated patients in dentoalveolar surgery: a clinical comparative study
Clinical Oral Investigations, 2019Co-Authors: Cm Schmitt, B Rusche, R Clemm, Fw Neukam, Mayte BuchbenderAbstract:Objectives This prospective, comparative, clinical study analyzed the postoperative bleeding risk of patients on anticoagulation therapy (AT) who were undergoing tooth Extractions and osteotomies. Materials and methods Patients with the following ATs were included (test groups): (1.) platelet aggregation inhibitors (PAIs), (2.) vitamin K inhibitors, (3.) low molecular weight heparin (LMWH), and (4.) direct oral anticoagulants (DOACs). Patients in the control group were not on any AT (non-AT group). Patients were subdivided into the following treatment groups: (1.) single tooth Extraction, (2.) Serial Extraction (≥ 2 adjacent teeth), and (3.) tooth osteotomy. Pre-, intra-, and postoperative data concerning the treatment, extent of the surgery, and bleeding were recorded and statistically evaluated. Results There were 15 postoperative bleeding events in 838 patients (1.7%): four (0.7%) in the non-AT group ( n = 603 patients) and 11 (4.7%) in the AT group ( n = 235 patients). The surgical procedure had no statistically significant effect on postoperative bleeding frequencies. Patients taking vitamin K inhibitors had a significantly higher risk of postoperative bleeding compared with patients without AT ( p < 0.00001). Four patients were hospitalized due to the severity of the bleeding (vitamin K inhibitor group). Postoperative bleeding events were all controlled with local hemostatic measures. Conclusions The postoperative bleeding risk after tooth Extractions and osteotomies in patients continuing AT is low, and bleeding can be controlled with local hemostatic measures. Clinical relevance AT should be continued in patients undergoing tooth removal procedures under the provision that local hemostatic measures are applied.
