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Rosalynd Gourgey - One of the best experts on this subject based on the ideXlab platform.
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defining challenge proven coexistent nut and Sesame Seed allergy a prospective multicenter european study
The Journal of Allergy and Clinical Immunology, 2020Co-Authors: Helen A Brough, Jeanchristoph Roger Jp Caubet, Angel Mazon, Diab Haddad, Marcel Bergmann, Jacqueline Wassenberg, Valentina Panetta, Rosalynd GourgeyAbstract:Background Peanut, tree nut, and Sesame allergies are responsible for most life-threatening food-induced allergic reactions. Rates of coexistent allergy between these foods have been from mostly retrospective studies that include only a limited number of tree nuts or were not based on oral food challenges. Objective The Pronuts study is a multicenter European study (London, Geneva, and Valencia) assessing the challenge-proven rate of coexistent peanut, tree nut, and/or Sesame Seed allergy. Methods Children aged 0 to 16 years with at least 1 confirmed nut or Sesame Seed allergy underwent sequential diagnostic food challenges to all other nuts and Sesame Seed. Results Overall, the rate of coexistent peanut, tree nut, and Sesame Seed allergy was 60.7% (n = 74/122; 95% CI, 51.4% to 69.4%). Peanut allergy was more common in London, cashew and pistachio nut allergies were more common in Geneva, and walnut and pecan allergies were more common in Valencia. Strong correlations were found between cashew-pistachio, walnut-pecan, and walnut-pecan-hazelnut-macadamia clusters. Age (>36 months) and center (Valencia > Geneva > London) were associated with an increased odds of multiple nut allergies. By pursuing the diagnostic protocol to demonstrate tolerance to other nuts, participants were able to introduce a median of 9 nuts. Conclusion We found a higher rate of coexistent nut and Sesame Seed allergies than previously reported. Performing sequential food challenges was labor intensive and could result in severe allergic reactions; however, it reduced dietary restrictions. Age was a significant predictor of multiple nut allergies, and thus the secondary spread of nut allergies occurred in older children.
Helen A Brough - One of the best experts on this subject based on the ideXlab platform.
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defining challenge proven coexistent nut and Sesame Seed allergy a prospective multicenter european study
The Journal of Allergy and Clinical Immunology, 2020Co-Authors: Helen A Brough, Jeanchristoph Roger Jp Caubet, Angel Mazon, Diab Haddad, Marcel Bergmann, Jacqueline Wassenberg, Valentina Panetta, Rosalynd GourgeyAbstract:Background Peanut, tree nut, and Sesame allergies are responsible for most life-threatening food-induced allergic reactions. Rates of coexistent allergy between these foods have been from mostly retrospective studies that include only a limited number of tree nuts or were not based on oral food challenges. Objective The Pronuts study is a multicenter European study (London, Geneva, and Valencia) assessing the challenge-proven rate of coexistent peanut, tree nut, and/or Sesame Seed allergy. Methods Children aged 0 to 16 years with at least 1 confirmed nut or Sesame Seed allergy underwent sequential diagnostic food challenges to all other nuts and Sesame Seed. Results Overall, the rate of coexistent peanut, tree nut, and Sesame Seed allergy was 60.7% (n = 74/122; 95% CI, 51.4% to 69.4%). Peanut allergy was more common in London, cashew and pistachio nut allergies were more common in Geneva, and walnut and pecan allergies were more common in Valencia. Strong correlations were found between cashew-pistachio, walnut-pecan, and walnut-pecan-hazelnut-macadamia clusters. Age (>36 months) and center (Valencia > Geneva > London) were associated with an increased odds of multiple nut allergies. By pursuing the diagnostic protocol to demonstrate tolerance to other nuts, participants were able to introduce a median of 9 nuts. Conclusion We found a higher rate of coexistent nut and Sesame Seed allergies than previously reported. Performing sequential food challenges was labor intensive and could result in severe allergic reactions; however, it reduced dietary restrictions. Age was a significant predictor of multiple nut allergies, and thus the secondary spread of nut allergies occurred in older children.
Shubing Chen - One of the best experts on this subject based on the ideXlab platform.
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antioxidant activity of brown pigment and extracts from black Sesame Seed sesamum indicum l
Food Chemistry, 2005Co-Authors: Shubing ChenAbstract:Abstract The antioxidant activities of brown pigment, extract of n-hexane and extract of supercritical carbon dioxide extraction of black Sesame Seeds were investigated in this study. Kinetics of anti-radical activity showed that the reaction between DPPH and brown pigment of Sesame Seed was rapid and reached the steady state in 10 min. Extracts from supercritical carbon dioxide extraction and n-hexane extraction reacted with DPPH slowly and the absorbance became stable after 35 min. However, α-tocopherol and trolox were rapid while the kinetic behaviour of BHA was intermediate. The brown pigment of Sesame Seed also showed a lower EC50 (13.5 μg ml−1) than the other two extracts and α-tocopherol, which was about 7–10 fold of the antioxidant activity of the supercritical carbon dioxide extract and the n-hexane extract. The ferric thiocyanate (FTC) method also showed that the brown pigment of Sesame Seed provided higher inhibition activity against lipid peroxidation at 200 μg ml−1 than did the supercritical carbon dioxide extract an n-hexane extract at 1 mg ml−1. However, the activities of the supercritical carbon dioxide extract and n-hexane extracts were significantly higher than that of α-tocopherol. In the linoleic acid system, the brown pigment of black Sesame Seed showed an equal antioxidant activity to BHA and higher than trolox and α-tocopherol. The results indicated that the brown pigment of Sesame Seed possessed excellent antioxidant activity.
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antioxidant activity of extracts of black Sesame Seed sesamum indicum l by supercritical carbon dioxide extraction
Journal of Agricultural and Food Chemistry, 2004Co-Authors: Shubing Chen, Fangmei YangAbstract:Antioxidant activities of extracts derived from Sesame Seed by supercritical carbon dioxide (SC-CO(2)) extraction and by n-hexane were determined using alpha,alpha-diphenyl-beta-picylhydrazyl (DPPH) radical scavenging and linoleic acid system methods. The highest extracted yield was given at 35 degrees C, 40 MPa, and a CO(2) flow rate of 2.5 mL min(-1) by an orthogonal experiment. The yields of extracts increased with increasing pressure, and yields at 40 and 30 MPa were higher than that by solvent extraction at 46.50%. Results from the linoleic acid system showed that the antioxidant activity follows the order: extract at 35 degrees C, 20 MPa > BHT > extract at 55 degrees C, 40 MPa > extract at 55 degrees C, 30 MPa > Trolox > solvent extraction > alpha-tocopherol. The SC-CO(2) extracts exhibited significantly higher antioxidant activities comparable to that by n-hexane extraction. The extracts at 30 MPa presented the highest antioxidant activities assessed in the DPPH method. At 20 MPa, the EC(50) increased with temperature, which indicated that the antioxidant activity was decreased in a temperature-dependent manner. The significant differences of antioxidant activities were found between the extracts by SC-CO(2) extraction and n-hexane. However, no significant differences were exhibited among the extracts by SC-CO(2) extraction. The vitamin E concentrations were also significantly higher in SC-CO(2) extracts than in n-hexane extracts, and its concentrations in extracts corresponded with the antioxidant activity of extracts.
Guina Mircea - One of the best experts on this subject based on the ideXlab platform.
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Time-resolved Raman spectrometer with high fluorescence rejection based on a CMOS SPAD line sensor and a 573 nm pulsed laser
'Institute of Electrical and Electronics Engineers (IEEE)', 2021Co-Authors: Talala Tuomo, Kaikkonen, Ville A., Keränen Pekka, Nikkinen Jari, Härkönen Antti, Savitski, Vasili G., Reilly Sean, Dziechciarczyk Łukasz, Kemp, Alan J., Guina MirceaAbstract:A time-resolved Raman spectrometer is demonstrated based on a 256 × 8 single-photon avalanche diodes fabricated in CMOS technology (CMOS SPAD) line sensor and a 573-nm fiber-coupled diamond Raman laser delivering pulses with duration below 100-ps full-width at half-maximum (FWHM). The collected backscattered light from the sample is dispersed on the line sensor using a custom volume holographic grating having 1800 lines/mm. Efficient fluorescence rejection in the Raman measurements is achieved due to a combination of time gating on sub-100-ps time scale and a 573-nm excitation wavelength. To demonstrate the performance of the spectrometer, fluorescent oil samples were measured. For organic Sesame Seed oil having a continuous wave (CW) mode fluorescence-to-Raman ratio of 10.5 and a fluorescence lifetime of 2.7 ns, a signal-to-distortion value of 76.2 was achieved. For roasted Sesame Seed oil having a CW mode fluorescence-to-Raman ratio of 82 and a fluorescence lifetime of 2.2 ns, a signal-to-distortion value of 28.2 was achieved. In both cases, the fluorescence-to-Raman ratio was reduced by a factor of 24–25 owing to time gating. For organic oil, spectral distortion was dominated by dark counts, while for the more fluorescent roasted oil, the main source of spectral distortion was timing skew of the sensor. With the presented postprocessing techniques, the level of distortion could be reduced by 88%–89% for both samples. Compared with common 532-nm excitation, approximately 73% lower fluorescence-to-Raman ratio was observed for 573-nm excitation when analyzing the organic Sesame Seed oil
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Time-resolved Raman spectrometer with high fluorescence rejection based on a CMOS SPAD line sensor and a 573 nm pulsed laser
'Institute of Electrical and Electronics Engineers (IEEE)', 2021Co-Authors: Talala Tuomo, Kaikkonen, Ville A., Keränen Pekka, Nikkinen Jari, Härkönen Antti, Savitski, Vasili G., Reilly Sean, Dziechciarczyk Łukasz, Kemp, Alan J., Guina MirceaAbstract:A time-resolved Raman spectrometer is demonstrated based on a 256\times 8 single-photon avalanche diodes fabricated in CMOS technology (CMOS SPAD) line sensor and a 573-nm fiber-coupled diamond Raman laser delivering pulses with duration below 100-ps full-width at half-maximum (FWHM). The collected backscattered light from the sample is dispersed on the line sensor using a custom volume holographic grating having 1800 lines/mm. Efficient fluorescence rejection in the Raman measurements is achieved due to a combination of time gating on sub-100-ps time scale and a 573-nm excitation wavelength. To demonstrate the performance of the spectrometer, fluorescent oil samples were measured. For organic Sesame Seed oil having a continuous wave (CW) mode fluorescence-to-Raman ratio of 10.5 and a fluorescence lifetime of 2.7 ns, a signal-to-distortion value of 76.2 was achieved. For roasted Sesame Seed oil having a CW mode fluorescence-to-Raman ratio of 82 and a fluorescence lifetime of 2.2 ns, a signal-to-distortion value of 28.2 was achieved. In both cases, the fluorescence-to-Raman ratio was reduced by a factor of 24-25 owing to time gating. For organic oil, spectral distortion was dominated by dark counts, while for the more fluorescent roasted oil, the main source of spectral distortion was timing skew of the sensor. With the presented postprocessing techniques, the level of distortion could be reduced by 88%-89% for both samples. Compared with common 532-nm excitation, approximately 73% lower fluorescence-to-Raman ratio was observed for 573-nm excitation when analyzing the organic Sesame Seed oil
Claudio Dariva - One of the best experts on this subject based on the ideXlab platform.
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extraction of Sesame Seed sesamun indicum l oil using compressed propane and supercritical carbon dioxide
Journal of Supercritical Fluids, 2010Co-Authors: Marines P Corso, Marcia Regina Fagundesklen, Edson Antonio Da Silva, Lucio Cardozo Filho, Juciara N Santos, Lisiane Dos Santos Freitas, Claudio DarivaAbstract:Abstract This work is aimed to investigate the extraction of Sesame Seed ( Sesamun indicum L.) oil using supercritical carbon dioxide and compressed propane as solvents. The extractions were performed in a laboratory scale unit in a temperature and pressure range of 313–333 K and 19–25 MPa for carbon dioxide and 303–333 K and 8–12 MPa for propane extractions, respectively. A 2 2 factorial experimental design with three replicates of the central point was adopted to organize the data collection for both solvents. The results indicated that solvent and density were important variables for the CO 2 extraction, while temperature is the most important variable for the extraction yield with propane. The extraction with propane was much faster than that with carbon dioxide due to the fact that propane is a better solvent for vegetable oils compared to carbon dioxide. On the other hand, characteristics of extracted oil, its oxidative stability determined by DSC and chemical profile of constituent fatty acids determined by gas chromatography, were similar to both solvents. The mathematical modeling of the extraction kinetics using a second order kinetic presented good results for the extraction with both solvents.