The Experts below are selected from a list of 129 Experts worldwide ranked by ideXlab platform
Motowo Mizuno - One of the best experts on this subject based on the ideXlab platform.
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post polypectomy bleeding in hot snare polypectomy of colonic polyps under continued warfarin or Short Interruption of direct oral anticoagulants
International Journal of Colorectal Disease, 2019Co-Authors: Yuichi Shimodate, Masayuki Ueno, Tomohiko Sunami, Hiroshi Takayama, Rio Takezawa, Naoyuki Nishimura, Hirokazu Mouri, Kazuhiro Matsueda, Hiroshi Yamamoto, Motowo MizunoAbstract:Newly published guidelines of the Japanese Gastroenterological Endoscopy Society (JGES) suggest to consider endoscopic procedures with high risk of bleeding without stopping warfarin and with stopping direct oral anticoagulants (DOACs) only on the day of the procedure. In this study, we aimed to test the validity of these recommendations. We retrospectively reviewed medical records of 344 patients with anticoagulant therapy who underwent hot-snare polypectomy between January 2012 and October 2018. Patients (n = 132) with Interruption of anticoagulants (3–7 days for warfarin and 2–3 days for DOACs before the procedure) and without heparin-bridging were excluded. Among the remaining 212 patients, the incidence of post-polypectomy bleeding was compared between the following 2 patient groups: patients who had Interruption of anticoagulants with heparin-bridging (HB group, n = 139) and patients treated according to the new JGES guideline (FG group, n = 73). The rate of post-polypectomy bleeding (PPB) in FG group (9.6%) was not significantly different from that in HB group (12.9%, p = 0.5). In subgroup analysis, the incidence of bleeding in patients with warfarin (12.2%) and with DOAC (6.3%) in FG group was not significantly different from corresponding figures in HB group (14.2%, 0%). In multivariate analysis, number of resected polyps was associated with PPB, but the administration of anticoagulants according to the new guidelines was not a significant risk factor for PPB (p = .98). Our study affirms the recommendations of JGES for the management of anticoagulants in patients who undergo colonic polypectomy regarding post-polypectomy bleeding.
Sara L Herd - One of the best experts on this subject based on the ideXlab platform.
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postprandial lipemia in endurance trained people during a Short Interruption to training
Journal of Applied Physiology, 1998Co-Authors: Adrianne E Hardman, Janet E M Lawrence, Sara L HerdAbstract:This study examined changes in postprandial lipemia in endurance-trained people during a Short Interruption to training. Nine men and one woman (ages 18–55 yr) undertook fat tolerance tests after 1...
Yuichi Shimodate - One of the best experts on this subject based on the ideXlab platform.
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post polypectomy bleeding in hot snare polypectomy of colonic polyps under continued warfarin or Short Interruption of direct oral anticoagulants
International Journal of Colorectal Disease, 2019Co-Authors: Yuichi Shimodate, Masayuki Ueno, Tomohiko Sunami, Hiroshi Takayama, Rio Takezawa, Naoyuki Nishimura, Hirokazu Mouri, Kazuhiro Matsueda, Hiroshi Yamamoto, Motowo MizunoAbstract:Newly published guidelines of the Japanese Gastroenterological Endoscopy Society (JGES) suggest to consider endoscopic procedures with high risk of bleeding without stopping warfarin and with stopping direct oral anticoagulants (DOACs) only on the day of the procedure. In this study, we aimed to test the validity of these recommendations. We retrospectively reviewed medical records of 344 patients with anticoagulant therapy who underwent hot-snare polypectomy between January 2012 and October 2018. Patients (n = 132) with Interruption of anticoagulants (3–7 days for warfarin and 2–3 days for DOACs before the procedure) and without heparin-bridging were excluded. Among the remaining 212 patients, the incidence of post-polypectomy bleeding was compared between the following 2 patient groups: patients who had Interruption of anticoagulants with heparin-bridging (HB group, n = 139) and patients treated according to the new JGES guideline (FG group, n = 73). The rate of post-polypectomy bleeding (PPB) in FG group (9.6%) was not significantly different from that in HB group (12.9%, p = 0.5). In subgroup analysis, the incidence of bleeding in patients with warfarin (12.2%) and with DOAC (6.3%) in FG group was not significantly different from corresponding figures in HB group (14.2%, 0%). In multivariate analysis, number of resected polyps was associated with PPB, but the administration of anticoagulants according to the new guidelines was not a significant risk factor for PPB (p = .98). Our study affirms the recommendations of JGES for the management of anticoagulants in patients who undergo colonic polypectomy regarding post-polypectomy bleeding.
Yasuki Kihara - One of the best experts on this subject based on the ideXlab platform.
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Periprocedural coagulability in patients undergoing ablation of atrial fibrillation: lessons from a periablation anticoagulation strategy of a brief withdrawal of warfarin without heparin bridging
Journal of Thrombosis and Thrombolysis, 2014Co-Authors: Akinori Sairaku, Yukihiko Yoshida, Haruo Hirayama, Yukiko Nakano, Yasuki KiharaAbstract:We aimed to examine what becomes of the coagulable state when warfarin is interrupted in patients undergoing ablation of atrial fibrillation (AF). We studied 62 patients with a CHADS_2 score of 0 or 1 who underwent ablation for paroxysmal AF. Warfarin was discontinued the day before the ablation without heparin-bridging, and intravenous heparin was administered during the procedure in a conventional manner, and warfarin was then resumed after achieving hemostasis of the access site. The international normalized ratio (INR) values or D-dimer levels were measured at five different time points during the periprocedural period, and the periprocedural hemorrhagic and thromboembolic complications were assessed. The INR value constantly decreased after withdrawal of warfarin, and did not recover to the level before its discontinuation at the time of hospital discharge despite a Short Interruption of warfarin (mean ± SD, 1.75 ± 0.52 to 1.41 ± 0.27, p
Pavel Mach - One of the best experts on this subject based on the ideXlab platform.
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Wireless Days - Performance of fast cell selection in two-tier OFDMA networks with small cells
2012 IFIP Wireless Days, 2012Co-Authors: Zdenek Becvar, Pavel MachAbstract:If large amount of small cells, i.e., femtocells, picocells or microcells, is deployed, users perform handover among small cells and macrocells very often. In OFDMA networks, only hard handover is usually supported as this type can be implemented easily. On the other hand, frequent hard handover negatively influence a quality of service experienced by users. The degradation of the quality is a consequence of a Short Interruption in communication during hard handover and due to redundant overhead generated for controlling and managing the handover procedure. This paper investigates performance of a fast cell selection applied in two-tier networks with small cells and compares it with the hard handover. We focus on the impact of a backhaul capacity limitation on the performance of both hard handover and fast cell selection. As our results indicate, there is a gain in throughput introduced by the fast cell selection if the backhaul of the small cells is not a bottleneck in term of capacity. Nevertheless, if the backhaul capacity is limited, the fast cell selection is profitable only for low bitrates. This observation indicates a need for mandatory consideration of the backhaul capacity for the fast cell selection in the networks with small cells.
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Performance of fast cell selection in two-tier OFDMA networks with small cells
2012 IFIP Wireless Days, 2012Co-Authors: Zdenek Becvar, Pavel MachAbstract:If large amount of small cells, i.e., femtocells, picocells or microcells, is deployed, users perform handover among small cells and macrocells very often. In OFDMA networks, only hard handover is usually supported as this type can be implemented easily. On the other hand, frequent hard handover negatively influence a quality of service experienced by users. The degradation of the quality is a consequence of a Short Interruption in communication during hard handover and due to redundant overhead generated for controlling and managing the handover procedure. This paper investigates performance of a fast cell selection applied in two-tier networks with small cells and compares it with the hard handover. We focus on the impact of a backhaul capacity limitation on the performance of both hard handover and fast cell selection. As our results indicate, there is a gain in throughput introduced by the fast cell selection if the backhaul of the small cells is not a bottleneck in term of capacity. Nevertheless, if the backhaul capacity is limited, the fast cell selection is profitable only for low bitrates. This observation indicates a need for mandatory consideration of the backhaul capacity for the fast cell selection in the networks with small cells.