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V. Shane Pankratz - One of the best experts on this subject based on the ideXlab platform.

  • Defining stroke risks in Sickle Cell Anemia
    Nature genetics, 2005
    Co-Authors: James F. Meschia, V. Shane Pankratz
    Abstract:

    Children and young adults with Sickle Cell Anemia at risk for stroke are identified principally by screening for cerebral vasculopathy using transcranial Doppler ultrasonography. Investigators now show how Bayesian networks can generate useful predictive models and highlight relationships between genes and the occurrence of stroke in those with Sickle Cell Anemia.

James F. Meschia - One of the best experts on this subject based on the ideXlab platform.

  • Defining stroke risks in Sickle Cell Anemia
    Nature genetics, 2005
    Co-Authors: James F. Meschia, V. Shane Pankratz
    Abstract:

    Children and young adults with Sickle Cell Anemia at risk for stroke are identified principally by screening for cerebral vasculopathy using transcranial Doppler ultrasonography. Investigators now show how Bayesian networks can generate useful predictive models and highlight relationships between genes and the occurrence of stroke in those with Sickle Cell Anemia.

At Chiabi - One of the best experts on this subject based on the ideXlab platform.

  • Surgery in Sickle Cell Anemia
    clinics in Mother and Child Health, 2004
    Co-Authors: P Fokam, At Chiabi
    Abstract:

    Sickle Cell Anemia is a hemoglobin disorder with a wide range of clinical manifestations and complications. Medical treatment is the mainstay of management but surgery is indicated in some cases. The authors review the main surgical indications in Sickle Cell Anemia as frequently encountered and review treatment guidelines. Keywords : Sickle Cell Anemia, surgery, indications Clinics in Mother and Child Health Vol. 1(1) 2004: 65-68

  • New concepts in Sickle Cell Anemia
    clinics in Mother and Child Health, 2004
    Co-Authors: At Chiabi, C Haenggeli
    Abstract:

    Current knowledge on the pathophysiology of Sickle Cell Anemia is reviewed and potential therapeutic options are reviewed and discussed. It is hoped that better understanding of the pathophysiology will improve the care given to these patients as well as their quality of life. Keywords : Sickle Cell Anemia, pathophysiology, treatment Clinics in Mother and Child Health Vol. 1(1) 2004: 30-36

Şinasi Özsoylu - One of the best experts on this subject based on the ideXlab platform.

  • Thrombocytosis in Sickle Cell Anemia
    Archives of pediatrics & adolescent medicine, 1997
    Co-Authors: Şinasi Özsoylu
    Abstract:

    In the July 1996 issue of theArchives, Quintana et al1described an adolescent girl with Sickle Cell Anemia and extreme thrombocytosis (platelet count, 2×1012/L). We2,3have also described thrombocytosis in patients with Sickle Cell Anemia; their platelet counts were higher than those in children who underwent splenectomy, but did not exceed 106/L. In addition to very high platelet counts, the patients described by Quintana et al showed some leukoerythroblastic features and abundancy of megakaryocytes in the bone marrow, with some erythroid hyperplasia. Although erythroid hyperplasia and erythroblastosis are expected in hemolytic Anemia including Sickle Cell disease, abundance of megakaryocytes and bone marrow picture (Figure 4, right, and Figure 31) make me suspicious about myelofibrosis. Was the patient's bone marrow sample stained for collagen and reticulin? May I also ask what do the authors mean by monozygous Sickle Cell Anemia? Would it be

Jane Hankins - One of the best experts on this subject based on the ideXlab platform.