The Experts below are selected from a list of 207 Experts worldwide ranked by ideXlab platform

Kamonwan Jenwitheesuk - One of the best experts on this subject based on the ideXlab platform.

  • Role of Silicone Derivative plus onion extract gel in presternal hypertrophic scar protection: a prospective randomized, double blinded, controlled trial.
    International wound journal, 2011
    Co-Authors: Kamonwan Jenwitheesuk, Palakorn Surakunprapha, Chusak Kuptarnond, Sompop Prathanee, Worawit Intanoo
    Abstract:

    Abstract Use of Silicone Derivative and onion extract had been reported in the prevention of hypertrophic scarring. Our experience showed the preventive use of Silicone Derivative plus onion extract gel on hypertrophic scars after median sternotomy. In a randomized, double blinded, placebo-controlled study, 60 patients after median sternotomy incisions were separated into two groups. All patients were treated either with Silicone Derivative plus onion extract gel (Cybele(®) scagel) or placebo gel twice daily for a total treatment period of 12 weeks. During each visit, pain and itching scores were graded by the patients and scar characteristics were observed by surgeons using the Vancouver scar scale. Pain and itch score values from patients' who applied Silicone Derivative plus onion extract gel was less than another group (P < 0·05). Pigmentation was significantly different between two groups (P < 0·05) and the reduction of scores on vascularity, pliability, height in treated group was not superior to the untreated group. No adverse events were reported by any of the patients. A Silicone Derivative plus onion extract gel is safe and effective for the preventing the hypertrophic scarring after median sternotomy.

Worawit Intanoo - One of the best experts on this subject based on the ideXlab platform.

  • Role of Silicone Derivative plus onion extract gel in presternal hypertrophic scar protection: a prospective randomized, double blinded, controlled trial.
    International wound journal, 2011
    Co-Authors: Kamonwan Jenwitheesuk, Palakorn Surakunprapha, Chusak Kuptarnond, Sompop Prathanee, Worawit Intanoo
    Abstract:

    Abstract Use of Silicone Derivative and onion extract had been reported in the prevention of hypertrophic scarring. Our experience showed the preventive use of Silicone Derivative plus onion extract gel on hypertrophic scars after median sternotomy. In a randomized, double blinded, placebo-controlled study, 60 patients after median sternotomy incisions were separated into two groups. All patients were treated either with Silicone Derivative plus onion extract gel (Cybele(®) scagel) or placebo gel twice daily for a total treatment period of 12 weeks. During each visit, pain and itching scores were graded by the patients and scar characteristics were observed by surgeons using the Vancouver scar scale. Pain and itch score values from patients' who applied Silicone Derivative plus onion extract gel was less than another group (P < 0·05). Pigmentation was significantly different between two groups (P < 0·05) and the reduction of scores on vascularity, pliability, height in treated group was not superior to the untreated group. No adverse events were reported by any of the patients. A Silicone Derivative plus onion extract gel is safe and effective for the preventing the hypertrophic scarring after median sternotomy.

A. Chuangsuwanich - One of the best experts on this subject based on the ideXlab platform.

  • Efficacy of the combination of herbal extracts and a Silicone Derivative in the treatment of hypertrophic scar formation after burn injury
    African Journal of Pharmacy and Pharmacology, 2011
    Co-Authors: Pornprom Muangman, Pornanong Aramwit, Sirinoot Palapinyo, Supaporn Opasanon, A. Chuangsuwanich
    Abstract:

    The development of hypertrophic scars is an unsolved problem in the process of wound healing. The objective of this research was to study the efficacy of the combination of herbal extracts and a Silicone Derivative in a gel preparation (Cybele®Scagel) on the treatment of deep second degree burns after complete epithelialization. Sixty-three patients were enrolled in this study. One wound area larger than 10 × 10 cm was selected from each patient to receive treatment with Cybele® Scagel. Patients were observed for pigmentation, pliability, pain and itching for 0, 2, 4, 8, 12, 16, 20 and 24 weeks after treatment. Their data and wound characteristics were collected during each visit using the Vancouver scar scale. After 24 weeks, all scales (pigmentation, pliability, pain and itching) were significantly lower in the sites treated with Cybele® Scagel compared with the previous time points (p 0.05). One patient was excluded at week 2 because of moderate itching at the wound site, which could have interfered with the evaluation. The application of Cybele® Scagel might have some beneficial effects for prevention of hypertrophic scar formation after partial thickness burn injuries.   Key words:  Herbal extracts, burn, hypertrophic scar.

Bandar El Fouhali - One of the best experts on this subject based on the ideXlab platform.

  • Free Radical UV-Curable Release Coatings Without Silicon Monomers Using Poly(methylhydrosiloxane) Co-Initiator
    Journal of Photopolymer Science and Technology, 2019
    Co-Authors: Abraham Chemtob, Bandar El Fouhali
    Abstract:

    To ensure easier removal of adhesive, backing materials can be coated with a release film. UV-curable release coatings based on acrylate or epoxy Silicone oligomers represent an increasing proportion of release liners available on the market. In order to alleviate their current problems of recycling, metal contamination and initiator insolubility, we have developed a synthetic methodology able to reduce Silicone content below 1 wt%. Silicon monomer-free, our approach relies on a type II radical photoinitiator consisting of benzophenone and poly(methylhydrosiloxane) (PMHS, 1600 g/mol), a Silicone Derivative with the general structure O-Si(H)(CH3). The ability for PMHS to act as co-initiator in radical photopolymerization is revealed by real-time Fourier transform IR spectroscopy. Release properties are evaluated through a probe tack experiment using a commercial pressure sensitive adhesive. Using 1,6-hexanediol diacrylate as resin, release properties are achieved at 1 wt% PMHS, and can be also maintained with poly(ethylene glycol) diacrylate, or tripropylene glycol diacrylate monomers. A ten times decrease in adhesion energy is observed when PMHS is used against a non-reactive Silicone thanks to chemical bonding between co-initiator and polymer network.

El Fouhali Anda - One of the best experts on this subject based on the ideXlab platform.

  • Free Radical UV-Curable Release Coatings Without Silicon Monomers Using Poly(methylhydrosiloxane) Co-Initiator
    Technical Assoc of Photopolymers Japan, 2019
    Co-Authors: Chemtob Abraham, El Fouhali Anda
    Abstract:

    International audienceTo ensure easier removal of adhesive, backing materials can be coated with a release film. UV-curable release coatings based on acrylate or epoxy Silicone oligomers represent an increasing proportion of release liners available on the market. In order to alleviate their current problems of recycling, metal contamination and initiator insolubility, we have developed a synthetic methodology able to reduce Silicone content below 1 wt%. Silicon monomer-free, our approach relies on a type II radical photoinitiator consisting of benzophenone and poly(methylhydrosiloxane) (PMHS, 1600 g/mol), a Silicone Derivative with the general structure O-Si(H)(CH3). The ability for PMHS to act as co-initiator in radical photopolymerization is revealed by real-time Fourier transform IR spectroscopy. Release properties are evaluated through a probe tack experiment using a commercial pressure sensitive adhesive. Using 1,6-hexanediol diacrylate as resin, release properties are achieved at 1 wt% PMHS, and can be also maintained with poly(ethylene glycol) diacrylate, or tripropylene glycol diacrylate monomers. A ten times decrease in adhesion energy is observed when PMHS is used against a non-reactive Silicone thanks to chemical bonding between co-initiator and polymer network