The Experts below are selected from a list of 5946 Experts worldwide ranked by ideXlab platform
V Leroy Young - One of the best experts on this subject based on the ideXlab platform.
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Biodurability of Retrieved Silicone Gel Breast Implants
Plastic and Reconstructive Surgery, 2003Co-Authors: Harold J. Brandon, K. L. Jerina, Clarence J. Wolf, V Leroy YoungAbstract:This study analyzed the shells of single-lumen Silicone Gel breast implants within the general context of device durability in vivo. The investigation included the major types of Gel-filled implants that were manufactured in the United States in a 30-year period. The implants analyzed were Cronin se
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Variability in the properties of Silicone Gel breast implants.
Plastic and reconstructive surgery, 2001Co-Authors: Harold J. Brandon, K. L. Jerina, V Leroy Young, Clarence J. WolfAbstract:Several generations of Silicone Gel breast implants have been produced by implant manufacturers. The primary material usually viewed as the base material in the manufacture of implants is polydimethylsiloxane. Polymeric reactions are notorious for their variability and nonuniformity. The elastomer used in different types of implants can have vastly different properties. Furthermore, the material properties associated with a particular type of implant can vary considerably from one lot to the next. Considering the various designs, styles, and manufacturing techniques associated with Silicone Gel implants, knowledge of the original properties of the implants before implantation is important in determining the effects of aging in vivo. This study was conducted to investigate differences in key mechanical and chemical properties of Silicone Gel breast implant materials. The two types of implants chosen for analysis were Silastic I and Silastic II control implants. Material property data were determined for both types of controls and significant differences were found in their values. Lot-to-lot variability was also investigated and found to be significant.
Travis T Tollefson - One of the best experts on this subject based on the ideXlab platform.
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R400 – Effects of Silicone Gel Sheeting on Scar Formation:
Otolaryngology-Head and Neck Surgery, 2008Co-Authors: Shervin Aminpour, Travis T TollefsonAbstract:ProblemThe treatment of keloids and hypertrophic scars has long been a concern for facial plastic surgeons. There are a wide variety of over-the-counter products that claim to improve hypertrophic scarring. Post-surgical patients often inquire as to which of these products will give the best cosmetic result. Silicone Gel sheeting is reported to provide positive outcomes with respect to a reduction in scar hypertrophy and an improvement in color differences. The exact mechanism is unknown. Micropore (3M) tape, a cheaper and more readily available product, has also been reported to reduce scar hypertrophy. This study will evaluate the differences and effectiveness of Silicone Gel sheeting and micropore tape in the reduction of scar hypertrophy in an animal model of scarring.MethodsHypertrophic scar formation was induced in an established rabbit model that parallels human skin. Treatment of the animals' scars was divided into 3 study groups: Silicone Gel sheeting, micropore tape, or no treatment. 80 total sc...
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R400 – Effects of Silicone Gel Sheeting on Scar Formation
Otolaryngology–Head and Neck Surgery, 2008Co-Authors: Shervin Aminpour, Travis T TollefsonAbstract:Problem The treatment of keloids and hypertrophic scars has long been a concern for facial plastic surgeons. There are a wide variety of over-the-counter products that claim to improve hypertrophic scarring. Post-surgical patients often inquire as to which of these products will give the best cosmetic result. Silicone Gel sheeting is reported to provide positive outcomes with respect to a reduction in scar hypertrophy and an improvement in color differences. The exact mechanism is unknown. Micropore (3M) tape, a cheaper and more readily available product, has also been reported to reduce scar hypertrophy. This study will evaluate the differences and effectiveness of Silicone Gel sheeting and micropore tape in the reduction of scar hypertrophy in an animal model of scarring. Methods Hypertrophic scar formation was induced in an established rabbit model that parallels human skin. Treatment of the animals' scars was divided into 3 study groups: Silicone Gel sheeting, micropore tape, or no treatment. 80 total scars were treated for 30 days after the complete reepithelialization of the created scars. Both photometric and histologic analysis was performed on the scars. Scar hypertrophy was analyzed with blinded observers using a visual analog scale. Histological analysis was performed using the Scar Elevation Index, a ratio of the scar height over normal skin. Results Both photographic and histological analysis showed there was a statistically significant improvement (p<0.05) in scar hypertrophy after use of either Silicone Gel sheeting and micropore tape when compared with controls. Conclusion Silicone Gel Sheeting and Micropore Tape are equally effective in the reduction of hypertrophic scarring. Significance Facial plastic surgeons should consider covering facial incisions with micropore tape for 30 days after surgery to minimize the risk of hypertrophic scarring.
Yehuda Shoenfeld - One of the best experts on this subject based on the ideXlab platform.
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Silicone Gel breast implants and connective tissue disease--a comprehensive review.
Autoimmunity, 2003Co-Authors: Eran Bar-meir, Michael Eherenfeld, Yehuda ShoenfeldAbstract:Silicone breast implants have been in use for breast reconstruction and breast augmentation for a long time. In the late 80's anecdotal reports describing a possible association between Silicone-Gel filled breast implants, and autoimmune diseases was accumulating. Due to the growing concern about the safety of Silicone-Gel implants, the Food and Drug administration (FDA) restricted their use to participants in controlled clinical trials, including women having reconstructive surgery. However, in recent years, large meta-analyses were unable to establish an association between Silicone-Gel breast implants and autoimmune disease. We review the current literature, emphasizing the most important epidemiologic studies.
Eran Bar-meir - One of the best experts on this subject based on the ideXlab platform.
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Silicone Gel-filled breast implants and breast cancer--an update and safety
Harefuah, 2004Co-Authors: Eyal Winkler, Eran Bar-meir, Eli Regev, Arie OrensteinAbstract:Silicone Gel-filled breast implants have long been an important method of breast reconstruction and breast augmentation. In 1992, the Food and Drug Administration (FDA), implemented a voluntary but strongly urged moratorium on the sale and use of Silicone Gel-filled breast implants. This was due to previous anecdotal reports regarding possible health hazards associated with these types of implants, including the emergence of breast cancer. The FDA allowed the use of Silicone Gel-filled breast implants for post-mastectomy reconstruction, and also in a small number of breast augmentation patients who were willing to enroll in a long-term prospective study. In this article, we review the current available literature that failed to produce any evidence associating the use of Silicone breast implants with the increased risk of breast cancer.
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Silicone Gel breast implants and connective tissue disease--a comprehensive review.
Autoimmunity, 2003Co-Authors: Eran Bar-meir, Michael Eherenfeld, Yehuda ShoenfeldAbstract:Silicone breast implants have been in use for breast reconstruction and breast augmentation for a long time. In the late 80's anecdotal reports describing a possible association between Silicone-Gel filled breast implants, and autoimmune diseases was accumulating. Due to the growing concern about the safety of Silicone-Gel implants, the Food and Drug administration (FDA) restricted their use to participants in controlled clinical trials, including women having reconstructive surgery. However, in recent years, large meta-analyses were unable to establish an association between Silicone-Gel breast implants and autoimmune disease. We review the current literature, emphasizing the most important epidemiologic studies.
Clarence J. Wolf - One of the best experts on this subject based on the ideXlab platform.
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Biodurability of Retrieved Silicone Gel Breast Implants
Plastic and Reconstructive Surgery, 2003Co-Authors: Harold J. Brandon, K. L. Jerina, Clarence J. Wolf, V Leroy YoungAbstract:This study analyzed the shells of single-lumen Silicone Gel breast implants within the general context of device durability in vivo. The investigation included the major types of Gel-filled implants that were manufactured in the United States in a 30-year period. The implants analyzed were Cronin se
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Variability in the properties of Silicone Gel breast implants.
Plastic and reconstructive surgery, 2001Co-Authors: Harold J. Brandon, K. L. Jerina, V Leroy Young, Clarence J. WolfAbstract:Several generations of Silicone Gel breast implants have been produced by implant manufacturers. The primary material usually viewed as the base material in the manufacture of implants is polydimethylsiloxane. Polymeric reactions are notorious for their variability and nonuniformity. The elastomer used in different types of implants can have vastly different properties. Furthermore, the material properties associated with a particular type of implant can vary considerably from one lot to the next. Considering the various designs, styles, and manufacturing techniques associated with Silicone Gel implants, knowledge of the original properties of the implants before implantation is important in determining the effects of aging in vivo. This study was conducted to investigate differences in key mechanical and chemical properties of Silicone Gel breast implant materials. The two types of implants chosen for analysis were Silastic I and Silastic II control implants. Material property data were determined for both types of controls and significant differences were found in their values. Lot-to-lot variability was also investigated and found to be significant.