The Experts below are selected from a list of 5175 Experts worldwide ranked by ideXlab platform
Richard J. Martin - One of the best experts on this subject based on the ideXlab platform.
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A silychristin isomer and variation of flavonolignan levels in milk thistle (Silybum marianum) fruits.
Planta medica, 2005Co-Authors: Wendy A. Smith, Denis R. Lauren, Elaine J. Burgess, Nigel B. Perry, Richard J. MartinAbstract:A new natural product has been isolated from silymarin, the hepatoprotective extract of milk thistle (Silybum marianum) fruits. This was shown by NMR spectroscopy to be silychristin B (8), a diastereoisomer of the known silychristin (7). Levels of these and the other flavonolignans varied markedly in fruits of different S. marianum samples.
T Kephalas - One of the best experts on this subject based on the ideXlab platform.
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FLAVONOLIGNAN PRODUCTION FROM Silybum MARIANUM TRANSFORMED AND UNTRANSFORMED ROOT CULTURES
Fitoterapia, 2000Co-Authors: F Alikaridis, D Papadakis, K Pantelia, T KephalasAbstract:Abstract Explants from seeds of Silybum marianum were used to produce either transformed (‘hairy’) or untransformed root cultures. Silybin, isosilybin, silychristin and silydianin were found in untransformed root cultures, by means of TLC and HPLC. In contrast, only isosilybin and traces of silychristin and silydianin were identified in the ‘hairy’ root cultures.
Ercan Bursal - One of the best experts on this subject based on the ideXlab platform.
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in vitro antioxidant activity of silymarin
Journal of Enzyme Inhibition and Medicinal Chemistry, 2009Co-Authors: Ekrem Koksal, Ilhami Gulcin, Sevim Beyza, Ozturk Sarikaya, Ercan BursalAbstract:Silymarin, a known standardized extract obtained from seeds of Silybum marianum is widely used in treatment of several diseases of varying origin. In the present paper, we clarified the antioxidant...
Veronika Butterweck - One of the best experts on this subject based on the ideXlab platform.
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in vitro inhibitory potential of cynara scolymus Silybum marianum taraxacum officinale and peumus boldus on key enzymes relevant to metabolic syndrome
Phytomedicine, 2015Co-Authors: Angela Villiger, Filippo Sala, Andy Suter, Veronika ButterweckAbstract:Boldocynara®, a proprietary dietary supplement product consisting of the plants Cynara scolymus, Silybum marianum, Taraxacum officinale, and Peumus boldus, used to promote functions of the liver and the gallbladder. It was the aim of the present study to look from a different perspective at the product by investigating the in vitro potential of Boldocynara® as a combination product and its individual extracts on key enzymes relevant to metabolic syndrome. Peumus boldus extract exhibited pronounced inhibitory activities on α-glucosidase (80% inhibition at 100 µg/ml, IC50: 17.56 µg/ml). Silybum marianum had moderate pancreatic lipase (PL) inhibitory activities (30% at 100 µg/ml) whereas Cynara scolymus showed moderate ACE inhibitory activity (31% at 100 µg/ml). The combination had moderate to weak effects on the tested enzymes. In conclusion, our results indicate some moderate potential of the dietary supplement Boldocynara® and its single ingredients for the prevention of metabolic disorders.
Wendy A. Smith - One of the best experts on this subject based on the ideXlab platform.
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A silychristin isomer and variation of flavonolignan levels in milk thistle (Silybum marianum) fruits.
Planta medica, 2005Co-Authors: Wendy A. Smith, Denis R. Lauren, Elaine J. Burgess, Nigel B. Perry, Richard J. MartinAbstract:A new natural product has been isolated from silymarin, the hepatoprotective extract of milk thistle (Silybum marianum) fruits. This was shown by NMR spectroscopy to be silychristin B (8), a diastereoisomer of the known silychristin (7). Levels of these and the other flavonolignans varied markedly in fruits of different S. marianum samples.
