The Experts below are selected from a list of 30 Experts worldwide ranked by ideXlab platform

Tomohiko Okawa - One of the best experts on this subject based on the ideXlab platform.

  • efficacy of Single Plane Implant technique in partial breast brachytherapy in small breasted patients
    International Journal of Radiation Oncology Biology Physics, 2020
    Co-Authors: Kazuhiko Sato, Hiromi Fuchikami, Naoko Takeda, Takahiro Shimo, Masahiro Kato, Tomohiko Okawa
    Abstract:

    PURPOSE: Partial-breast irradiation (PBI) using multicatheter-interstitial brachytherapy (MIB) has been supported by some randomized trials to date. However, it remains underused in Asian countries because of the population's typically smaller breasts. Single-Plane Implantation has been recommended in these individuals, but limited data on the clinical efficacy exist. We performed a retrospective chart review to compare the tumor control and long-term cosmesis in patients treated with the Single-Plane Implant technique. METHODS AND MATERIALS: Patients receiving MIB-PBI between October 2008 and December 2018 were evaluated. PBI was initiated on the same day of the surgery via an intraoperative catheter Implant, delivering 32 Gy by 8 fractions. Tumor control based on the rate of freedom from ipsilateral tumor recurrence (IBTR), disease-free survival, and long-term cosmesis using the Harvard scale was evaluated to compare between the Single- and double-/triple-Plane Implant techniques. RESULTS: Five hundred sixteen patients with 526 lesions received MIB-PBI with a median follow-up of 53.1 months. Patients treated by Single- and double- or triple-Plane Implant numbered 288 (54.8%) and 238 (45.2%), respectively. The 4-year probabilities of IBTR-free survival and disease-free survival were 97.5% and 96.5% in Single-Plane Implant and 98.6% (P = .42) and 98.0% (P = .18) in double- or triple-Plane Implant MIB-PBI, respectively. Although young age (P < .05) and positive surgical margins (P < .01) were selected as independent risk factors for IBTR, Single-Plane Implantation was not recognized as a risk factor of IBTR. Sixty-one of 69 Single-Plane Implant patients (88.4%) and 84 of 92 double-/triple-Plane Implant patients (91.3%) reported excellent to good cosmetic results (P = .73). CONCLUSIONS: Although this was a retrospective study from a Single institution and cosmesis was evaluated using a subjective method, this is the first report to validate Single-Plane Implant MIB-PBI for use in small-breasted patients. Further multicenter research is required.

Kazuhiko Sato - One of the best experts on this subject based on the ideXlab platform.

  • efficacy of Single Plane Implant technique in partial breast brachytherapy in small breasted patients
    International Journal of Radiation Oncology Biology Physics, 2020
    Co-Authors: Kazuhiko Sato, Hiromi Fuchikami, Naoko Takeda, Takahiro Shimo, Masahiro Kato, Tomohiko Okawa
    Abstract:

    PURPOSE: Partial-breast irradiation (PBI) using multicatheter-interstitial brachytherapy (MIB) has been supported by some randomized trials to date. However, it remains underused in Asian countries because of the population's typically smaller breasts. Single-Plane Implantation has been recommended in these individuals, but limited data on the clinical efficacy exist. We performed a retrospective chart review to compare the tumor control and long-term cosmesis in patients treated with the Single-Plane Implant technique. METHODS AND MATERIALS: Patients receiving MIB-PBI between October 2008 and December 2018 were evaluated. PBI was initiated on the same day of the surgery via an intraoperative catheter Implant, delivering 32 Gy by 8 fractions. Tumor control based on the rate of freedom from ipsilateral tumor recurrence (IBTR), disease-free survival, and long-term cosmesis using the Harvard scale was evaluated to compare between the Single- and double-/triple-Plane Implant techniques. RESULTS: Five hundred sixteen patients with 526 lesions received MIB-PBI with a median follow-up of 53.1 months. Patients treated by Single- and double- or triple-Plane Implant numbered 288 (54.8%) and 238 (45.2%), respectively. The 4-year probabilities of IBTR-free survival and disease-free survival were 97.5% and 96.5% in Single-Plane Implant and 98.6% (P = .42) and 98.0% (P = .18) in double- or triple-Plane Implant MIB-PBI, respectively. Although young age (P < .05) and positive surgical margins (P < .01) were selected as independent risk factors for IBTR, Single-Plane Implantation was not recognized as a risk factor of IBTR. Sixty-one of 69 Single-Plane Implant patients (88.4%) and 84 of 92 double-/triple-Plane Implant patients (91.3%) reported excellent to good cosmetic results (P = .73). CONCLUSIONS: Although this was a retrospective study from a Single institution and cosmesis was evaluated using a subjective method, this is the first report to validate Single-Plane Implant MIB-PBI for use in small-breasted patients. Further multicenter research is required.

Naoko Takeda - One of the best experts on this subject based on the ideXlab platform.

  • efficacy of Single Plane Implant technique in partial breast brachytherapy in small breasted patients
    International Journal of Radiation Oncology Biology Physics, 2020
    Co-Authors: Kazuhiko Sato, Hiromi Fuchikami, Naoko Takeda, Takahiro Shimo, Masahiro Kato, Tomohiko Okawa
    Abstract:

    PURPOSE: Partial-breast irradiation (PBI) using multicatheter-interstitial brachytherapy (MIB) has been supported by some randomized trials to date. However, it remains underused in Asian countries because of the population's typically smaller breasts. Single-Plane Implantation has been recommended in these individuals, but limited data on the clinical efficacy exist. We performed a retrospective chart review to compare the tumor control and long-term cosmesis in patients treated with the Single-Plane Implant technique. METHODS AND MATERIALS: Patients receiving MIB-PBI between October 2008 and December 2018 were evaluated. PBI was initiated on the same day of the surgery via an intraoperative catheter Implant, delivering 32 Gy by 8 fractions. Tumor control based on the rate of freedom from ipsilateral tumor recurrence (IBTR), disease-free survival, and long-term cosmesis using the Harvard scale was evaluated to compare between the Single- and double-/triple-Plane Implant techniques. RESULTS: Five hundred sixteen patients with 526 lesions received MIB-PBI with a median follow-up of 53.1 months. Patients treated by Single- and double- or triple-Plane Implant numbered 288 (54.8%) and 238 (45.2%), respectively. The 4-year probabilities of IBTR-free survival and disease-free survival were 97.5% and 96.5% in Single-Plane Implant and 98.6% (P = .42) and 98.0% (P = .18) in double- or triple-Plane Implant MIB-PBI, respectively. Although young age (P < .05) and positive surgical margins (P < .01) were selected as independent risk factors for IBTR, Single-Plane Implantation was not recognized as a risk factor of IBTR. Sixty-one of 69 Single-Plane Implant patients (88.4%) and 84 of 92 double-/triple-Plane Implant patients (91.3%) reported excellent to good cosmetic results (P = .73). CONCLUSIONS: Although this was a retrospective study from a Single institution and cosmesis was evaluated using a subjective method, this is the first report to validate Single-Plane Implant MIB-PBI for use in small-breasted patients. Further multicenter research is required.

Takahiro Shimo - One of the best experts on this subject based on the ideXlab platform.

  • efficacy of Single Plane Implant technique in partial breast brachytherapy in small breasted patients
    International Journal of Radiation Oncology Biology Physics, 2020
    Co-Authors: Kazuhiko Sato, Hiromi Fuchikami, Naoko Takeda, Takahiro Shimo, Masahiro Kato, Tomohiko Okawa
    Abstract:

    PURPOSE: Partial-breast irradiation (PBI) using multicatheter-interstitial brachytherapy (MIB) has been supported by some randomized trials to date. However, it remains underused in Asian countries because of the population's typically smaller breasts. Single-Plane Implantation has been recommended in these individuals, but limited data on the clinical efficacy exist. We performed a retrospective chart review to compare the tumor control and long-term cosmesis in patients treated with the Single-Plane Implant technique. METHODS AND MATERIALS: Patients receiving MIB-PBI between October 2008 and December 2018 were evaluated. PBI was initiated on the same day of the surgery via an intraoperative catheter Implant, delivering 32 Gy by 8 fractions. Tumor control based on the rate of freedom from ipsilateral tumor recurrence (IBTR), disease-free survival, and long-term cosmesis using the Harvard scale was evaluated to compare between the Single- and double-/triple-Plane Implant techniques. RESULTS: Five hundred sixteen patients with 526 lesions received MIB-PBI with a median follow-up of 53.1 months. Patients treated by Single- and double- or triple-Plane Implant numbered 288 (54.8%) and 238 (45.2%), respectively. The 4-year probabilities of IBTR-free survival and disease-free survival were 97.5% and 96.5% in Single-Plane Implant and 98.6% (P = .42) and 98.0% (P = .18) in double- or triple-Plane Implant MIB-PBI, respectively. Although young age (P < .05) and positive surgical margins (P < .01) were selected as independent risk factors for IBTR, Single-Plane Implantation was not recognized as a risk factor of IBTR. Sixty-one of 69 Single-Plane Implant patients (88.4%) and 84 of 92 double-/triple-Plane Implant patients (91.3%) reported excellent to good cosmetic results (P = .73). CONCLUSIONS: Although this was a retrospective study from a Single institution and cosmesis was evaluated using a subjective method, this is the first report to validate Single-Plane Implant MIB-PBI for use in small-breasted patients. Further multicenter research is required.

Masahiro Kato - One of the best experts on this subject based on the ideXlab platform.

  • efficacy of Single Plane Implant technique in partial breast brachytherapy in small breasted patients
    International Journal of Radiation Oncology Biology Physics, 2020
    Co-Authors: Kazuhiko Sato, Hiromi Fuchikami, Naoko Takeda, Takahiro Shimo, Masahiro Kato, Tomohiko Okawa
    Abstract:

    PURPOSE: Partial-breast irradiation (PBI) using multicatheter-interstitial brachytherapy (MIB) has been supported by some randomized trials to date. However, it remains underused in Asian countries because of the population's typically smaller breasts. Single-Plane Implantation has been recommended in these individuals, but limited data on the clinical efficacy exist. We performed a retrospective chart review to compare the tumor control and long-term cosmesis in patients treated with the Single-Plane Implant technique. METHODS AND MATERIALS: Patients receiving MIB-PBI between October 2008 and December 2018 were evaluated. PBI was initiated on the same day of the surgery via an intraoperative catheter Implant, delivering 32 Gy by 8 fractions. Tumor control based on the rate of freedom from ipsilateral tumor recurrence (IBTR), disease-free survival, and long-term cosmesis using the Harvard scale was evaluated to compare between the Single- and double-/triple-Plane Implant techniques. RESULTS: Five hundred sixteen patients with 526 lesions received MIB-PBI with a median follow-up of 53.1 months. Patients treated by Single- and double- or triple-Plane Implant numbered 288 (54.8%) and 238 (45.2%), respectively. The 4-year probabilities of IBTR-free survival and disease-free survival were 97.5% and 96.5% in Single-Plane Implant and 98.6% (P = .42) and 98.0% (P = .18) in double- or triple-Plane Implant MIB-PBI, respectively. Although young age (P < .05) and positive surgical margins (P < .01) were selected as independent risk factors for IBTR, Single-Plane Implantation was not recognized as a risk factor of IBTR. Sixty-one of 69 Single-Plane Implant patients (88.4%) and 84 of 92 double-/triple-Plane Implant patients (91.3%) reported excellent to good cosmetic results (P = .73). CONCLUSIONS: Although this was a retrospective study from a Single institution and cosmesis was evaluated using a subjective method, this is the first report to validate Single-Plane Implant MIB-PBI for use in small-breasted patients. Further multicenter research is required.