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A K Sethi - One of the best experts on this subject based on the ideXlab platform.

  • an unusual complication of Sinus Arrest following right sided stellate ganglion block a case report
    Pain Practice, 2004
    Co-Authors: Ashok Kumar Saxena, Neeraj Saxena, Bhavna Aggarwal, A K Sethi
    Abstract:

    We present a case of a 29-year-old female patient who had presented to us for the management of her chronic right shoulder-hand pain and developed a Sinus Arrest following a right-sided stellate ganglion block (RSGB). This patient on receiving a diagnostic RSGB via the anterior paratracheal (C6) approach developed Sinus Arrest followed by apnea and unconsciousness. On institution of resuscitative measures involving tracheal intubation, positive pressure ventilation, cardiac massage, and intravenous atropine, spontaneous cardiac activity recovered in about 3 minutes. Other signs and symptoms resolved fully in a total of 10 minutes. She had persistent postural hypotension lasting for about 24 hours requiring bed rest and was discharged about 36 hours after the procedure, without any adverse sequelae. As the Sinus node is supplied by the right-sided sympathetic chain, its blockade probably resulted in unopposed parasympathetic activity leading to asystole. Available evidence of the role of right stellate ganglion in regulation of cardiac electrophysiology and functioning is also discussed.

Jianhua Yan - One of the best experts on this subject based on the ideXlab platform.

  • aging associated Sinus Arrest and sick Sinus syndrome in adult zebrafish
    PLOS ONE, 2020
    Co-Authors: Jianhua Yan, Kunli Jiao, Alex X Zhang, Hung Cao, Yonghe Ding
    Abstract:

    Because of its powerful genetics, the adult zebrafish has been increasingly used for studying cardiovascular diseases. Considering its heart rate of ~100 beats per minute at ambient temperature, which is very close to human, we assessed the use of this vertebrate animal for modeling heart rhythm disorders such as Sinus Arrest (SA) and sick Sinus syndrome (SSS). We firstly optimized a protocol to measure electrocardiogram in adult zebrafish. We determined the location of the probes, implemented an open-chest microsurgery procedure, measured the effects of temperature, and determined appropriate anesthesia dose and time. We then proposed an PP interval of more than 1.5 seconds as an arbitrary criterion to define an SA episode in an adult fish at ambient temperature, based on comparison between the current definition of an SA episode in humans and our studies of candidate SA episodes in aged wild-type fish and Tg(SCN5A-D1275N) fish (a fish model for inherited SSS). With this criterion, a subpopulation of about 5% wild-type fish can be considered to have SA episodes, and this percentage significantly increases to about 25% in 3-year-old fish. In response to atropine, this subpopulation has both common SSS phenotypic traits that are shared with the Tg(SCN5A-D1275N) model, such as bradycardia; and unique SSS phenotypic traits, such as increased QRS/P ratio and chronotropic incompetence. In summary, this study defined baseline SA and SSS in adult zebrafish and underscored use of the zebrafish as an alternative model to study aging-associated SSS.

Prescott Wiske - One of the best experts on this subject based on the ideXlab platform.

Ashok Kumar Saxena - One of the best experts on this subject based on the ideXlab platform.

  • an unusual complication of Sinus Arrest following right sided stellate ganglion block a case report
    Pain Practice, 2004
    Co-Authors: Ashok Kumar Saxena, Neeraj Saxena, Bhavna Aggarwal, A K Sethi
    Abstract:

    We present a case of a 29-year-old female patient who had presented to us for the management of her chronic right shoulder-hand pain and developed a Sinus Arrest following a right-sided stellate ganglion block (RSGB). This patient on receiving a diagnostic RSGB via the anterior paratracheal (C6) approach developed Sinus Arrest followed by apnea and unconsciousness. On institution of resuscitative measures involving tracheal intubation, positive pressure ventilation, cardiac massage, and intravenous atropine, spontaneous cardiac activity recovered in about 3 minutes. Other signs and symptoms resolved fully in a total of 10 minutes. She had persistent postural hypotension lasting for about 24 hours requiring bed rest and was discharged about 36 hours after the procedure, without any adverse sequelae. As the Sinus node is supplied by the right-sided sympathetic chain, its blockade probably resulted in unopposed parasympathetic activity leading to asystole. Available evidence of the role of right stellate ganglion in regulation of cardiac electrophysiology and functioning is also discussed.

Imran Arif - One of the best experts on this subject based on the ideXlab platform.

  • a case of Sinus Arrest with ticagrelor use
    Journal of the American College of Cardiology, 2020
    Co-Authors: Shaheer Zulfiqar, Fayez Siddiqui, Fahad Waqar, Imran Arif
    Abstract:

    Ticagrelor is often the preferred antiplatelet agent in acute coronary syndrome (ACS). We present a rare case of Sinus Arrest after ticagrelor use needing temporary pacing and change of antiplatelet therapy. A 65-year-old man with no known heart disease presented with unstable angina. His baseline