The Experts below are selected from a list of 201 Experts worldwide ranked by ideXlab platform
Sujata Gaitonde - One of the best experts on this subject based on the ideXlab platform.
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primary pancreatic Sinus Histiocytosis with massive lymphadenopathy rosai dorfman disease an unusual extranodal manifestation clinically simulating malignancy
Archives of Pathology & Laboratory Medicine, 2010Co-Authors: Mark Podberezin, Ronald M Angeles, Grace Guzman, David Peace, Sujata GaitondeAbstract:Abstract Sinus Histiocytosis with massive lymphadenopathy (SHML), also called Rosai-Dorfman disease, is a rare entity. Its etiology and pathogenesis are still essentially unclear. The histologic ha...
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multifocal extranodal Sinus Histiocytosis with massive lymphadenopathy an overview
Archives of Pathology & Laboratory Medicine, 2009Co-Authors: Sujata GaitondeAbstract:Abstract Context.—This article provides an overview of the major pathologic manifestations of Sinus Histiocytosis with massive lymphadenopathy, including patient characteristics and current knowledge about its pathogenesis, with an emphasis on multifocal and extranodal presentation. Sinus Histiocytosis with massive lymphadenopathy is a rare, nonneoplastic, idiopathic, proliferative histiocytic disorder; recognition of this disorder is important to avoid misinterpretation and subsequent unnecessary treatment. This is especially true for primary extranodal manifestation of this rare disorder. Although accurate diagnosis of this entity requires a correlation of clinical, radiologic, laboratory, and pathologic studies in most cases, it remains a disorder primarily defined by its histopathologic features and pathologic manifestations, which are key to the diagnosis. Objective.—To summarize the scientific literature, provide a concise review, and emphasize the diagnostic histopathologic features of extranodal s...
C Adamsbaum - One of the best experts on this subject based on the ideXlab platform.
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lacrimal location of Sinus Histiocytosis destombes rosai dorfman disease
American Journal of Neuroradiology, 2004Co-Authors: Robin Azoulay, H Brisse, Paul Freneaux, S Ferey, G Kalifa, C AdamsbaumAbstract:Summary: A 7-year-old West African male patient presented with recurrence of multiple cervical lymphadenopathy. Cervical node biopsy disclosed a Sinus Histiocytosis with massive lymphadenopathy (Rosai-Dorfman-Destombes disease). During follow-up, the patient developed a left orbital mass corresponding to an enlarged lacrimal gland shown by CT. The histologic features of the gland were consistent with the diagnosis, and with steroid treatment, the gland decreased in size. Although rare, the diagnosis of Sinus Histiocytosis with massive lymphadenopathy has to be considered in cases of lacrimal gland enlargement.
Hans E Grossniklaus - One of the best experts on this subject based on the ideXlab platform.
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Sinus Histiocytosis presenting as bilateral epibulbar masses
American Journal of Ophthalmology, 1999Co-Authors: K C Ireland, Amy K Hutchinson, Hans E GrossniklausAbstract:PURPOSE: To report a case of Sinus Histiocytosis presenting as multiple, bilateral epibulbar masses. METHODS: We examined a 4-year-old child with a 2-month history of gradually enlarging, salmon-colored epibulbar masses. Excisional biopsies and a systemic evaluation were performed. RESULTS: Systemic evaluation was normal; no lymphadenopathy was documented. Histopathologic evaluation disclosed features consistent with Sinus Histiocytosis. Flow cytometry and gene rearrangement studies confirmed the benign nature of the disease. No tumor recurrence was noted. CONCLUSION: Sinus Histiocytosis may present as isolated epibulbar masses that may be treated with surgical excision.
Alexanderkai So - One of the best experts on this subject based on the ideXlab platform.
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Sinus Histiocytosis with massive lymphadenopathy rosai dorfman disease and oligoarthritis
Joint Bone Spine, 2011Co-Authors: Julien Castioni, Anca Mihaescu, Alexanderkai SoAbstract:A 24-year-old woman who had Sinus Histiocytosis with massive lymphadenopathy (SHML, Rosai-Dorfman disease) also had oligoarthritis. We found only four previously reported cases of SHML with clinical joint disease. The clinical picture may suggest rheumatoid arthritis or a spondylarthropathy with peripheral joint involvement. SHML should be considered routinely among the differential diagnoses in young patients with arthritis and large lymphadenopathies. There is no consensus regarding the treatment. In our patient, conventional disease-modifying antirheumatic drugs followed by 3 months of adalimumab then 3 months of etanercept had no effect on the symptoms.
Robin Azoulay - One of the best experts on this subject based on the ideXlab platform.
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lacrimal location of Sinus Histiocytosis destombes rosai dorfman disease
American Journal of Neuroradiology, 2004Co-Authors: Robin Azoulay, H Brisse, Paul Freneaux, S Ferey, G Kalifa, C AdamsbaumAbstract:Summary: A 7-year-old West African male patient presented with recurrence of multiple cervical lymphadenopathy. Cervical node biopsy disclosed a Sinus Histiocytosis with massive lymphadenopathy (Rosai-Dorfman-Destombes disease). During follow-up, the patient developed a left orbital mass corresponding to an enlarged lacrimal gland shown by CT. The histologic features of the gland were consistent with the diagnosis, and with steroid treatment, the gland decreased in size. Although rare, the diagnosis of Sinus Histiocytosis with massive lymphadenopathy has to be considered in cases of lacrimal gland enlargement.