The Experts below are selected from a list of 318 Experts worldwide ranked by ideXlab platform

Patriek Mistiaen - One of the best experts on this subject based on the ideXlab platform.

  • prevention and treatment of intertrigo in large Skin Folds of adults a systematic review
    BMC Nursing, 2010
    Co-Authors: Patriek Mistiaen, Meike Van Halmwalters
    Abstract:

    Background Intertrigo in the large Skin Folds is a common problem. There is a plethora of treatments, but a lack of evidence about their efficacy. A nursing guideline on this matter had to be updated and broadened in scope to other health care professionals.

  • Prevention and treatment of intertrigo in large Skin Folds of adults: a systematic review
    BMC Nursing, 2010
    Co-Authors: Patriek Mistiaen, Meike Van Halm-walters
    Abstract:

    Background Intertrigo in the large Skin Folds is a common problem. There is a plethora of treatments, but a lack of evidence about their efficacy. A nursing guideline on this matter had to be updated and broadened in scope to other health care professionals. Methods A systematic review was performed. Thirteen databases were sensitively searched, supplemented by reference tracking and forward citation searches. All types of empirical research relating to the prevention or treatment of intertrigo were included. Study selection, assessment of bias, data-extraction and analysis were done by two independent review-authors. Results Sixty-eight studies fulfilled the inclusion criteria. Only 4 studies were RCTs and even these had a considerable risk of bias. Study populations were generally small. No studies were found about the prevention of intertrigo. The therapies concerned mostly the topical application of antimycotics, corticosteroids, antibiotics, antiseptics or a combination of these. Besides these pharmaceutical interventions, surgical breast reduction was also studied. Although most study-authors were positive, we could not draw firm conclusions about any of the pharmaceutical interventions. Even patients that received placebo intervention showed improvement. There is weak evidence that reduction mammaplasty may be helpful to treat inframammary intertrigo. All research found had considerable risk of bias, prohibiting firm conclusions. Conclusions There is no evidence at all about the prevention of intertrigo and there is no firm evidence about its treatment. Well designed studies are needed.

  • preventing and treating intertrigo in the large Skin Folds of adults a literature overview
    Dermatology nursing, 2004
    Co-Authors: Patriek Mistiaen, Else Poot, Sophie Hickox, Christ Jochems, C Wagner
    Abstract:

    Intertrigo is an inflammatory dermatosis of the Skin Folds of the body, for which a large variety of topical medications may be recommended. A systematic literature review was performed to find scientific evidence for preventing and treating intertrigo within the nursing domain. Seven electronic databases were searched with a simple broad-scope search strategy. The aim was to identify all publications that concerned intertrigo itself and other conditions that were related to intertriginous regions. This search produced 451 references. A final set of 24 studies was retained and analyzed on content and methodologic quality. Most studies concerned treatments with antifungals or disinfectants in heterogeneous research samples, with only small subsamples of people with intertrigo. Six studies were randomized controlled trials. In general, the methodologic quality of the studies was poor. The analyzed studies provided no scientific evidence for any type of nursing prevention or treatment strategy. There is a great need for well-designed clinical studies on intertrigo. (aut.ref.)

  • Preventing and treating intertrigo in the large Skin Folds of adults: a literature overview.
    Dermatology nursing, 2004
    Co-Authors: Patriek Mistiaen, Else Poot, Sophie Hickox, Christ Jochems, C Wagner
    Abstract:

    Intertrigo is an inflammatory dermatosis of the Skin Folds of the body, for which a large variety of topical medications may be recommended. A systematic literature review was performed to find scientific evidence for preventing and treating intertrigo within the nursing domain. Seven electronic databases were searched with a simple broad-scope search strategy. The aim was to identify all publications that concerned intertrigo itself and other conditions that were related to intertriginous regions. This search produced 451 references. A final set of 24 studies was retained and analyzed on content and methodologic quality. Most studies concerned treatments with antifungals or disinfectants in heterogeneous research samples, with only small subsamples of people with intertrigo. Six studies were randomized controlled trials. In general, the methodologic quality of the studies was poor. The analyzed studies provided no scientific evidence for any type of nursing prevention or treatment strategy. There is a great need for well-designed clinical studies on intertrigo.

John M. Opitz - One of the best experts on this subject based on the ideXlab platform.

  • A case of Kabuki (Niikawa-Kuroki) syndrome associated with manifestations resembling C-trigonocephaly syndrome.
    American journal of medical genetics. Part A, 2004
    Co-Authors: Grace David, David Sillence, Robert Hardwick, John M. Opitz
    Abstract:

    We report a 2-year-old boy with overlapping manifestations of the Kabuki (Niikawa-Kuroki) and Opitz trigonocephaly syndromes. The proband was initially diagnosed with Opitz trigonocephaly syndrome on the basis of metopic craniosynostosis, upslanting palpebral fissures, high arched palate, redundant Skin Folds at the back of the neck, ventricular septal defect, broad flat thumbs, bilateral single palmar creases, left talipes equinovarus, eventration of right hemidiaphragm, and bilateral inguinal hernia. However, as he grew older, his facial profile changed to that typical of Kabuki syndrome.

  • a case of kabuki niikawa kuroki syndrome associated with manifestations resembling c trigonocephaly syndrome
    American Journal of Medical Genetics Part A, 2004
    Co-Authors: Grace David, David Sillence, Robert Hardwick, John M. Opitz
    Abstract:

    We report a 2-year-old boy with overlapping manifestations of the Kabuki (Niikawa–Kuroki) and Opitz trigonocephaly syndromes. The proband was initially diagnosed with Opitz trigonocephaly syndrome on the basis of metopic craniosynostosis, upslanting palpebral fissures, high arched palate, redundant Skin Folds at the back of the neck, ventricular septal defect, broad flat thumbs, bilateral single palmar creases, left talipes equinovarus, eventration of right hemidiaphragm, and bilateral inguinal hernia. However, as he grew older, his facial profile changed to that typical of Kabuki syndrome. © 2004 Wiley-Liss, Inc.

  • A case of Kabuki (Niikawa‐Kuroki) syndrome associated with manifestations resembling C‐trigonocephaly syndrome
    American Journal of Medical Genetics Part A, 2004
    Co-Authors: Grace David, David Sillence, Robert Hardwick, John M. Opitz
    Abstract:

    We report a 2-year-old boy with overlapping manifestations of the Kabuki (Niikawa–Kuroki) and Opitz trigonocephaly syndromes. The proband was initially diagnosed with Opitz trigonocephaly syndrome on the basis of metopic craniosynostosis, upslanting palpebral fissures, high arched palate, redundant Skin Folds at the back of the neck, ventricular septal defect, broad flat thumbs, bilateral single palmar creases, left talipes equinovarus, eventration of right hemidiaphragm, and bilateral inguinal hernia. However, as he grew older, his facial profile changed to that typical of Kabuki syndrome. © 2004 Wiley-Liss, Inc.

David Sillence - One of the best experts on this subject based on the ideXlab platform.

  • A case of Kabuki (Niikawa-Kuroki) syndrome associated with manifestations resembling C-trigonocephaly syndrome.
    American journal of medical genetics. Part A, 2004
    Co-Authors: Grace David, David Sillence, Robert Hardwick, John M. Opitz
    Abstract:

    We report a 2-year-old boy with overlapping manifestations of the Kabuki (Niikawa-Kuroki) and Opitz trigonocephaly syndromes. The proband was initially diagnosed with Opitz trigonocephaly syndrome on the basis of metopic craniosynostosis, upslanting palpebral fissures, high arched palate, redundant Skin Folds at the back of the neck, ventricular septal defect, broad flat thumbs, bilateral single palmar creases, left talipes equinovarus, eventration of right hemidiaphragm, and bilateral inguinal hernia. However, as he grew older, his facial profile changed to that typical of Kabuki syndrome.

  • a case of kabuki niikawa kuroki syndrome associated with manifestations resembling c trigonocephaly syndrome
    American Journal of Medical Genetics Part A, 2004
    Co-Authors: Grace David, David Sillence, Robert Hardwick, John M. Opitz
    Abstract:

    We report a 2-year-old boy with overlapping manifestations of the Kabuki (Niikawa–Kuroki) and Opitz trigonocephaly syndromes. The proband was initially diagnosed with Opitz trigonocephaly syndrome on the basis of metopic craniosynostosis, upslanting palpebral fissures, high arched palate, redundant Skin Folds at the back of the neck, ventricular septal defect, broad flat thumbs, bilateral single palmar creases, left talipes equinovarus, eventration of right hemidiaphragm, and bilateral inguinal hernia. However, as he grew older, his facial profile changed to that typical of Kabuki syndrome. © 2004 Wiley-Liss, Inc.

  • A case of Kabuki (Niikawa‐Kuroki) syndrome associated with manifestations resembling C‐trigonocephaly syndrome
    American Journal of Medical Genetics Part A, 2004
    Co-Authors: Grace David, David Sillence, Robert Hardwick, John M. Opitz
    Abstract:

    We report a 2-year-old boy with overlapping manifestations of the Kabuki (Niikawa–Kuroki) and Opitz trigonocephaly syndromes. The proband was initially diagnosed with Opitz trigonocephaly syndrome on the basis of metopic craniosynostosis, upslanting palpebral fissures, high arched palate, redundant Skin Folds at the back of the neck, ventricular septal defect, broad flat thumbs, bilateral single palmar creases, left talipes equinovarus, eventration of right hemidiaphragm, and bilateral inguinal hernia. However, as he grew older, his facial profile changed to that typical of Kabuki syndrome. © 2004 Wiley-Liss, Inc.

Julio Correa - One of the best experts on this subject based on the ideXlab platform.

  • Inverse Psoriasis Involving Genital Skin Folds: Successful Therapy with Dapsone
    Dermatology and therapy, 2012
    Co-Authors: Antonio Guglielmetti, Rodrigo Conlledo, Juliana Bedoya, Francisco Ianiszewski, Julio Correa
    Abstract:

    Introduction Inverse psoriasis is a rare form of psoriasis that affects between 3% and 7% of the patients with psoriasis. It can comprise genital Skin Folds as part of genital psoriasis, and it is one of the most commonly seen dermatoses of this area. There are few evidence-based studies about the treatment of intertriginous psoriasis involving genital Skin Folds.

  • Inverse Psoriasis Involving Genital Skin Folds: Successful Therapy with Dapsone
    Dermatology and Therapy, 2012
    Co-Authors: Antonio Guglielmetti, Rodrigo Conlledo, Juliana Bedoya, Francisco Ianiszewski, Julio Correa
    Abstract:

    Introduction Inverse psoriasis is a rare form of psoriasis that affects between 3% and 7% of the patients with psoriasis. It can comprise genital Skin Folds as part of genital psoriasis, and it is one of the most commonly seen dermatoses of this area. There are few evidence-based studies about the treatment of intertriginous psoriasis involving genital Skin Folds. Case Presentation The authors present a 42-year-old female patient with erythematous plaques in the vulva, groin, and perianal region. The patient had previously received a broad range of topical and systemic therapies that had to be discontinued due to ineffectiveness or side effects. She was treated with 100 mg dapsone daily for 10 months, showing a significant improvement of her cutaneous and mucous lesions. Complete clearance of psoriatic lesions was observed after 4 weeks of treatment. She has remained in remission for up to 2 years, using only topical therapy with tacrolimus 0.1% and calcipotriol. Discussion Genital psoriasis is a Skin disease that causes great discomfort. It is important to include examination of the genital region and to adopt this conduct in daily clinical practice. Research in this field is still poor, making no discrimination between flexural and genital psoriasis, and is based on case series and expert opinion; therefore, empirical recommendations for the treatment of genital psoriasis remain. Dapsone has been shown to be an effective and convenient alternative for the treatment of inverse psoriasis in genital Skin Folds, which can provide effective control of the disease. Further studies are required to determine the efficacy and safety of current therapies, and to decide whether dapsone therapy should be considered in the management of this form of psoriasis when topical and other systemic agents are not effective.

Meike Van Halm-walters - One of the best experts on this subject based on the ideXlab platform.

  • Prevention and treatment of intertrigo in large Skin Folds of adults: a systematic review
    BMC Nursing, 2010
    Co-Authors: Patriek Mistiaen, Meike Van Halm-walters
    Abstract:

    Background Intertrigo in the large Skin Folds is a common problem. There is a plethora of treatments, but a lack of evidence about their efficacy. A nursing guideline on this matter had to be updated and broadened in scope to other health care professionals. Methods A systematic review was performed. Thirteen databases were sensitively searched, supplemented by reference tracking and forward citation searches. All types of empirical research relating to the prevention or treatment of intertrigo were included. Study selection, assessment of bias, data-extraction and analysis were done by two independent review-authors. Results Sixty-eight studies fulfilled the inclusion criteria. Only 4 studies were RCTs and even these had a considerable risk of bias. Study populations were generally small. No studies were found about the prevention of intertrigo. The therapies concerned mostly the topical application of antimycotics, corticosteroids, antibiotics, antiseptics or a combination of these. Besides these pharmaceutical interventions, surgical breast reduction was also studied. Although most study-authors were positive, we could not draw firm conclusions about any of the pharmaceutical interventions. Even patients that received placebo intervention showed improvement. There is weak evidence that reduction mammaplasty may be helpful to treat inframammary intertrigo. All research found had considerable risk of bias, prohibiting firm conclusions. Conclusions There is no evidence at all about the prevention of intertrigo and there is no firm evidence about its treatment. Well designed studies are needed.