The Experts below are selected from a list of 276 Experts worldwide ranked by ideXlab platform

V. Ramesh - One of the best experts on this subject based on the ideXlab platform.

  • Cutaneous Tuberculosis in Children
    Pediatric Dermatology, 2012
    Co-Authors: Gomathy Sethuraman, V. Ramesh
    Abstract:

    :  Cutaneous Tuberculosis is a rare form of extrapulmonary Tuberculosis that accounts for 1% to 2% of cases. Childhood Skin Tuberculosis represents 18% to 82% of all cutaneous Tuberculosis cases. Scrofuloderma and lupus vulgaris are the two most common clinical forms in children. An increase in the number of tuberculids, especially lichen scrofulosorum, has been observed in the last several years. Cutaneous Tuberculosis in children can be severe and have a protracted course. Multiplicity of lesions and multifocal disseminated involvement in scrofuloderma and lupus vulgaris is common. Scrofuloderma progressing to gummatous lesions (scrofulous gumma) is mostly described in children. Morbidities and deformities are more severe in children.

  • Skin Tuberculosis in children learning from india
    Dermatologic Clinics, 2008
    Co-Authors: V. Ramesh, Gomathy Sethuraman, M Ramam, Vinod K Sharma
    Abstract:

    Cutaneous Tuberculosis in children is a major health problem in India. It accounts for about 1.5% of all the cases of extrapulmonary Tuberculosis. Scrofuloderma and lupus vulgaris are the two most common forms of Tuberculosis. However, the trend in the pattern of cutaneous Tuberculosis is changing, as the tuberculid, lichen scrofulosorum, has become more common in recent years. Overall, the clinical patterns are comparable with adults. However, children can have widespread and severe involvement because many unusual and uncommon patterns are known to occur in children. Underlying systemic involvement is more common in children, compared with adults.

  • A study of cutaneous Tuberculosis in children
    Pediatric Dermatology, 1999
    Co-Authors: V. Ramesh, R.s. Misra, Beena Kr, A. Mukherjee
    Abstract:

    : Sixty-three children out of a total of 199 patients seen with cutaneous Tuberculosis during a 7-year period were included in this study. Culture was positive in only four, and the diagnosis was based on clinical examination, tuberculin reaction, histopathology, and response to antitubercular therapy. Forty had lupus vulgaris (LV) and 23 scrofuloderma (SD). The lower half of the body was predominantly affected in those with LV, and keratotic and hypertrophic forms were frequently encountered. LV planus mainly affected the face. Ulcerative and atrophic types of LV were infrequent. Extensive lesions in three children led to disfiguring scars and contractures. Scrofuloderma often involved the cervical group of lymph nodes followed by the inguinal, submandibular, and axillary groups. As compared to Skin Tuberculosis in adults, regional lymph node involvement in LV was more common, and a combination of both LV and SD was less frequent in children. No difference in clinical presentation could be detected between the BCG vaccinated and unvaccinated children. Tuberculous infection either in the lungs or the bones was present in eight children. An HIV test done in five patients with widespread lesions was negative. Irregular therapy or late diagnosis leading to serious complications, inadequate parental or community support, and lack of awareness among practitioners are the problems to be remedied.

  • Serodiagnostic value of the 19 kilodalton antigen ofMycobacterium Tuberculosis in indian patients
    European Journal of Clinical Microbiology and Infectious Diseases, 1992
    Co-Authors: G. Bothamley, V. Ramesh, H. Batra, A. Chandramui, J. Ivanyi
    Abstract:

    Previous studies in UK subjects suggested that the 19 kDa protein antigen of Mycobacterium Tuberculosis might be valuable in the serodiagnosis of paucibacillary Tuberculosis. In this study, antibody titres for the 19 kDa antigen were higher in healthy controls in India than in the UK. Consequently, the diagnostic sensitivity of this antigen and its TB23 epitope was negligible in Indian patients with Tuberculosis. However, a diagnostic sensitivity of 50 % was achieved in patients with Skin Tuberculosis on the basis of a high ratio between antibody titres for the whole antigen and its TB23 epitope.

  • Serodiagnostic value of the 19 kilodalton antigen of Mycobacterium Tuberculosis in indian patients
    European Journal of Clinical Microbiology & Infectious Diseases, 1992
    Co-Authors: G. Bothamley, V. Ramesh, A. Chandramui, H. V. Batra, J. Ivanyi
    Abstract:

    Previous studies in UK subjects suggested that the 19 kDa protein antigen ofMycobacterium Tuberculosis might be valuable in the serodiagnosis of paucibacillary Tuberculosis. In this study, antibody titres for the 19 kDa antigen were higher in healthy controls in India than in the UK. Consequently, the diagnostic sensitivity of this antigen and its TB23 epitope was negligible in Indian patients with Tuberculosis. However, a diagnostic sensitivity of 50 % was achieved in patients with Skin Tuberculosis on the basis of a high ratio between antibody titres for the whole antigen and its TB23 epitope.

J. Ivanyi - One of the best experts on this subject based on the ideXlab platform.

G. Bothamley - One of the best experts on this subject based on the ideXlab platform.

R. Okuyama - One of the best experts on this subject based on the ideXlab platform.

  • Squamous cell carcinoma arising from lupus vulgaris with a >60-year history
    International Cancer Conference Journal, 2017
    Co-Authors: T. Miyake, H. Uhara, N. Ishii, R. Okuyama
    Abstract:

    We report the case of a 71-year-old Japanese man with squamous cell carcinoma arising from lupus vulgaris on the face, >60 years after the appearance of the lupus vulgaris. The red plaque on the patient’s face had been diagnosed as a hemangioma or rosacea at several hospitals, although he had had lung Tuberculosis at the age of 4 and his father died from lung Tuberculosis at 38 years of age. Although lupus vulgaris was the most frequent clinical form of true Skin Tuberculosis until the 1960s, it has become rare since then. Malignant tumors are known to occur in individuals with lupus vulgaris, with a reported rate of 0.5–10.5%. In light of Japan’s “graying society,” Tuberculosis is still an important disorder, and clinicians must remain aware of cutaneous Tuberculosis.

  • Squamous cell carcinoma arising from lupus vulgaris with a >60-year history
    International cancer conference journal, 2017
    Co-Authors: T. Miyake, H. Uhara, N. Ishii, R. Okuyama
    Abstract:

    We report the case of a 71-year-old Japanese man with squamous cell carcinoma arising from lupus vulgaris on the face, >60 years after the appearance of the lupus vulgaris. The red plaque on the patient’s face had been diagnosed as a hemangioma or rosacea at several hospitals, although he had had lung Tuberculosis at the age of 4 and his father died from lung Tuberculosis at 38 years of age. Although lupus vulgaris was the most frequent clinical form of true Skin Tuberculosis until the 1960s, it has become rare since then. Malignant tumors are known to occur in individuals with lupus vulgaris, with a reported rate of 0.5–10.5%. In light of Japan’s “graying society,” Tuberculosis is still an important disorder, and clinicians must remain aware of cutaneous Tuberculosis.

A. Chandramui - One of the best experts on this subject based on the ideXlab platform.