The Experts below are selected from a list of 102 Experts worldwide ranked by ideXlab platform

Young Il Min - One of the best experts on this subject based on the ideXlab platform.

  • appendiceal orifice inflammation as a Skip Lesion in ulcerative colitis an analysis in relation to medical therapy and disease extent
    Gastrointestinal Endoscopy, 1999
    Co-Authors: Sukkyun Yang, Hwoonyong Jung, Gyeong Hoon Kang, Young Min Kim, Seungjae Myung, Ki Nam Shim, Weonseon Hong, Young Il Min
    Abstract:

    Abstract Background: Although several reports have claimed that the appendix can be involved as a Skip Lesion in ulcerative colitis, they do not exclude the possibility that this Skip Lesion occurs as a result of medical therapy. Also, little is known about the relation between the presence of appendiceal orifice inflammation and the extent of the disease. Methods: The presence of appendiceal orifice inflammation was prospectively assessed both endoscopically and histologically in 94 patients with active ulcerative colitis, the extent of whose disease had not been beyond the hepatic flexure. To evaluate the effect of prior medical therapy on the prevalence of appendiceal orifice inflammation, all cases were divided into two groups. Group A consisted of 66 patients who had been treated before inclusion; group B was composed of 28 patients newly diagnosed at inclusion. Results: Appendiceal orifice inflammation was diagnosed in 24 (26%) of 94 patients with active subtotal ulcerative colitis, with no statistical difference observed between group A (23%) and group B (32%). In all 94 patients, the frequency of appendiceal orifice inflammation decreased significantly as the extent of disease increased, i.e., 37% in proctitis (n = 49), 17% in left-sided colitis (n = 36), and 0% in extensive colitis (n = 9) ( p Conclusions: Appendiceal orifice inflammation as a Skip Lesion of ulcerative colitis is not rare, is more frequently observed in patients with less extensive disease, and is not the result of patchy improvement due to medical therapy. (Gastrointest Endosc 1999;49:743-7.)

Sukkyun Yang - One of the best experts on this subject based on the ideXlab platform.

  • Atypical Distribution of Inflammation in Newly Diagnosed Ulcerative Colitis is not Rare
    Hindawi Limited, 2014
    Co-Authors: Sang Hyoung Park, Sukkyun Yang, Soo-kyung Park, Jong Wook Kim, Dong-hoon Yang, Kee Wook Jung, Kyung-jo Kim, Jeong-sik Byeon, Seungjae Myung
    Abstract:

    BACKGROUND: Appendiceal orifice inflammation (AOI) is a common ‘Skip Lesion’ in patients with ulcerative colitis (UC). However, other Skip Lesions are less well known

  • appendiceal orifice inflammation as a Skip Lesion in ulcerative colitis an analysis in relation to medical therapy and disease extent
    Gastrointestinal Endoscopy, 1999
    Co-Authors: Sukkyun Yang, Hwoonyong Jung, Gyeong Hoon Kang, Young Min Kim, Seungjae Myung, Ki Nam Shim, Weonseon Hong, Young Il Min
    Abstract:

    Abstract Background: Although several reports have claimed that the appendix can be involved as a Skip Lesion in ulcerative colitis, they do not exclude the possibility that this Skip Lesion occurs as a result of medical therapy. Also, little is known about the relation between the presence of appendiceal orifice inflammation and the extent of the disease. Methods: The presence of appendiceal orifice inflammation was prospectively assessed both endoscopically and histologically in 94 patients with active ulcerative colitis, the extent of whose disease had not been beyond the hepatic flexure. To evaluate the effect of prior medical therapy on the prevalence of appendiceal orifice inflammation, all cases were divided into two groups. Group A consisted of 66 patients who had been treated before inclusion; group B was composed of 28 patients newly diagnosed at inclusion. Results: Appendiceal orifice inflammation was diagnosed in 24 (26%) of 94 patients with active subtotal ulcerative colitis, with no statistical difference observed between group A (23%) and group B (32%). In all 94 patients, the frequency of appendiceal orifice inflammation decreased significantly as the extent of disease increased, i.e., 37% in proctitis (n = 49), 17% in left-sided colitis (n = 36), and 0% in extensive colitis (n = 9) ( p Conclusions: Appendiceal orifice inflammation as a Skip Lesion of ulcerative colitis is not rare, is more frequently observed in patients with less extensive disease, and is not the result of patchy improvement due to medical therapy. (Gastrointest Endosc 1999;49:743-7.)

M S Rao - One of the best experts on this subject based on the ideXlab platform.

  • appendiceal involvement as a Skip Lesion in ulcerative colitis
    Modern Pathology, 1994
    Co-Authors: Steven H Kroft, Steven J Stryker, M S Rao
    Abstract:

    Despite the frequency of ulcerative colitis (UC), and numerous studies related to this disease, controversy remains regarding its distribution patterns. It is generally believed that UC starts in the rectum and progresses proximally in continuity to involve cecum along with appendix in 50% of all cases. However, recent endoscopic and histological studies suggest that UC can occur as a discontinuous process. Furthermore, the few existing studies specifically addressing appendiceal histology in UC are divided over whether ulcerative appendicitis (UA) may be seen without cecal involvement (i.e., as a "Skip Lesion"). To study the appendiceal pathology in UC, and in particular the frequency of UA as a "Skip Lesion," we retrospectively evaluated 39 proctocolectomy specimens containing appendices removed for UC. Six cases (17%) had obliterated appendices; appendiceal and cecal histologies of the remaining 33 cases were divided into (a) active disease, (b) quiescent disease, or (c) nonspecific or normal histology. Twenty of 39 appendices (51%) showed active disease, four (10%) had quiescent disease, and nine (23%) were either normal or nonspecifically inflamed. After exclusion of one case for inadequate cecal sampling, comparison of cecal and appendiceal histologies showed concordance in 16 cases and discordance in the remaining 16. Of these discordant cases, six had greater disease activity in the cecum and 10 had greater activity in the appendix. Of these latter 10 cases, six showed normal or nonspecific cecal histology associated with active UA. Thus, "Skip Lesions" of the appendix were detected in 15% of the UC specimens examined.

Seungjae Myung - One of the best experts on this subject based on the ideXlab platform.

  • Atypical Distribution of Inflammation in Newly Diagnosed Ulcerative Colitis is not Rare
    Hindawi Limited, 2014
    Co-Authors: Sang Hyoung Park, Sukkyun Yang, Soo-kyung Park, Jong Wook Kim, Dong-hoon Yang, Kee Wook Jung, Kyung-jo Kim, Jeong-sik Byeon, Seungjae Myung
    Abstract:

    BACKGROUND: Appendiceal orifice inflammation (AOI) is a common ‘Skip Lesion’ in patients with ulcerative colitis (UC). However, other Skip Lesions are less well known

  • appendiceal orifice inflammation as a Skip Lesion in ulcerative colitis an analysis in relation to medical therapy and disease extent
    Gastrointestinal Endoscopy, 1999
    Co-Authors: Sukkyun Yang, Hwoonyong Jung, Gyeong Hoon Kang, Young Min Kim, Seungjae Myung, Ki Nam Shim, Weonseon Hong, Young Il Min
    Abstract:

    Abstract Background: Although several reports have claimed that the appendix can be involved as a Skip Lesion in ulcerative colitis, they do not exclude the possibility that this Skip Lesion occurs as a result of medical therapy. Also, little is known about the relation between the presence of appendiceal orifice inflammation and the extent of the disease. Methods: The presence of appendiceal orifice inflammation was prospectively assessed both endoscopically and histologically in 94 patients with active ulcerative colitis, the extent of whose disease had not been beyond the hepatic flexure. To evaluate the effect of prior medical therapy on the prevalence of appendiceal orifice inflammation, all cases were divided into two groups. Group A consisted of 66 patients who had been treated before inclusion; group B was composed of 28 patients newly diagnosed at inclusion. Results: Appendiceal orifice inflammation was diagnosed in 24 (26%) of 94 patients with active subtotal ulcerative colitis, with no statistical difference observed between group A (23%) and group B (32%). In all 94 patients, the frequency of appendiceal orifice inflammation decreased significantly as the extent of disease increased, i.e., 37% in proctitis (n = 49), 17% in left-sided colitis (n = 36), and 0% in extensive colitis (n = 9) ( p Conclusions: Appendiceal orifice inflammation as a Skip Lesion of ulcerative colitis is not rare, is more frequently observed in patients with less extensive disease, and is not the result of patchy improvement due to medical therapy. (Gastrointest Endosc 1999;49:743-7.)

Abdul Muthalib - One of the best experts on this subject based on the ideXlab platform.

  • ewing sarcoma of the left big toe with trans articular Skip Lesion a case report
    Medical Journal of Indonesia, 2009
    Co-Authors: Ahmad F. Kamal, Muhammad Nagieb, Errol U. Hutagalung, Bambang Budiatmoko, Saukani Gumay, Abdul Muthalib
    Abstract:

    We report the case of the patient who had Ewing Sarcoma in whom radiological and hystopathological appearances revealed a tumor mass in the left big toe along with trans-artikular Skip Lesion on the left diaphysis of tibia. In Cipto Mangunkusomo Hospital since 1995 until 2004 we have found 20 Ewing sarcoma cases, but only one Skip Lesion Ewing sarcoma was found. The diagnosis of transarticular Skip Lesion in association of Ewing sarcoma was confirmed in clinicopathological conferrence. The initial evaluation of all patients included the recording of the medical history, physical examination, and hematological studies. Radiographs of the chest and the site of the primary tumor were made routinely. Systemic staging was performed with use of total-body bone scan. Ray amputation of left big toe and open biopsy from mass of mid-shaft of tibia had been done to confirm the diagnosis. The patient underwent induction chemotherapy and above knee amputation. Ten months after diagnosis, he died because of advanced-distant metastasis. (Med J Indones 2008; 18: 139-44)Key words: Ewing sarcoma, trans-articular Skip Lesion

  • Ewing sarcoma of the left big toe with trans-articular Skip Lesion
    Faculty of Medicine Universitas Indonesia, 2009
    Co-Authors: Ahmad F. Kamal, Muhammad Nagieb, Errol U. Hutagalung, Bambang Budiatmoko, Saukani Gumay, Abdul Muthalib
    Abstract:

    We report the case of the patient who had Ewing Sarcoma in whom radiological and hystopathological appearances revealed a tumor mass in the left big toe along with trans-artikular Skip Lesion on the left diaphysis of tibia. In Cipto Mangunkusomo Hospital since 1995 until 2004 we have found 20 Ewing sarcoma cases, but only one Skip Lesion Ewing sarcoma was found. The diagnosis of transarticular Skip Lesion in association of Ewing sarcoma was confirmed in clinicopathological conferrence. The initial evaluation of all patients included the recording of the medical history, physical examination, and hematological studies. Radiographs of the chest and the site of the primary tumor were made routinely. Systemic staging was performed with use of total-body bone scan. Ray amputation of left big toe and open biopsy from mass of mid-shaft of tibia had been done to confirm the diagnosis. The patient underwent induction chemotherapy and above knee amputation. Ten months after diagnosis, he died because of advanced-distant metastasis. (Med J Indones 2008; 18: 139-44)Key words: Ewing sarcoma, trans-articular Skip Lesion