The Experts below are selected from a list of 267 Experts worldwide ranked by ideXlab platform
Nicholas J Talley - One of the best experts on this subject based on the ideXlab platform.
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prevalence and Socioeconomic Impact of upper gastrointestinal disorders in the united states results of the us upper gastrointestinal study
Clinical Gastroenterology and Hepatology, 2005Co-Authors: Michael Camilleri, Dominique Dubois, Michael P Jones, Pete J Kahrilas, Anne M Rentz, Amno Sonnenberg, Vincenzo Stanghellini, Walte F Stewa, Ja Tack, Nicholas J TalleyAbstract:Background & Aims: This study examined the prevalence of upper gastrointestinal (GI) symptoms and symptom groupings and determined Impact on disability days in a nationally representative US sample. Methods: A telephone survey of 21,128 adults was conducted including questions about the presence of upper GI symptoms during the past 3 months. Respondents were categorized as symptomatic (ie, reported GI symptoms once per month) or asymptomatic. The survey included questions about missed work, leisure activity, or household activity days. Symptom groupings were identified by using factor analysis, and cluster analysis was used to assign respondents into distinct groups on the basis of these symptom groupings. Results: The prevalence of an average of 1 or more upper GI symptoms during the past 3 months was 44.9%. The most common symptoms experienced during the past 3 months were early satiety, heartburn, and postprandial fullness. Factor analysis identified 4 symptom groupings: (1) heartburn/regurgitation; (2) nausea/vomiting; (3) bloating/abdominal pain; and (4) early satiety/loss of appetite. Five respondent clusters were identified; the largest clusters were primarily early satiety/fullness (44%) and gastroesophageal reflux disease-like symptoms (28%). Two small clusters reflected nausea and vomiting (7%) and a heterogeneous symptom profile (4%). Symptomatic respondents reported significantly more missed work, leisure, and household activity days than asymptomatic respondents (all P Conclusions: Factor analysis separated GI symptoms into groupings reflecting gastroesophageal reflux disease and dyspepsia: early satiety, postprandial fullness, and loss of appetite; bloating and abdominal pain/discomfort; and nausea and vomiting. These upper GI symptoms were associated with significant loss of work and activity days.
Susan L Tighe - One of the best experts on this subject based on the ideXlab platform.
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development of a management framework for rural roads in developing countries integrating Socioeconomic Impacts
Transportation Research Record, 2009Co-Authors: Alondra Chamorro, Susan L TigheAbstract:During the past decade, considerable efforts have been made to valuate the benefits of investments in rural roads in developing countries. Although the outputs of those studies have led to a global rethinking of traditional road appraisal methods, limited attempts have been made to integrate these findings into the rural road management process. The problem that arises from the analysis is a missing link between the appraisal of the Socioeconomic Impact and the management of rural roads. The main objective of the present study was to develop a methodology that combined all key aspects required for the sustainable management of rural roads in developing countries. For this, social, technical, economic, political, and sustainability aspects must be considered at the different levels of the management process. A case study developed in Chile is presented to illustrate the application of the proposed framework at the strategic and the network levels. From the application it was concluded that it was possible to combine in a practical and integrated tool all key factors affecting the process of management of rural roads in developing countries.
Michael Camilleri - One of the best experts on this subject based on the ideXlab platform.
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prevalence and Socioeconomic Impact of upper gastrointestinal disorders in the united states results of the us upper gastrointestinal study
Clinical Gastroenterology and Hepatology, 2005Co-Authors: Michael Camilleri, Dominique Dubois, Michael P Jones, Pete J Kahrilas, Anne M Rentz, Amno Sonnenberg, Vincenzo Stanghellini, Walte F Stewa, Ja Tack, Nicholas J TalleyAbstract:Background & Aims: This study examined the prevalence of upper gastrointestinal (GI) symptoms and symptom groupings and determined Impact on disability days in a nationally representative US sample. Methods: A telephone survey of 21,128 adults was conducted including questions about the presence of upper GI symptoms during the past 3 months. Respondents were categorized as symptomatic (ie, reported GI symptoms once per month) or asymptomatic. The survey included questions about missed work, leisure activity, or household activity days. Symptom groupings were identified by using factor analysis, and cluster analysis was used to assign respondents into distinct groups on the basis of these symptom groupings. Results: The prevalence of an average of 1 or more upper GI symptoms during the past 3 months was 44.9%. The most common symptoms experienced during the past 3 months were early satiety, heartburn, and postprandial fullness. Factor analysis identified 4 symptom groupings: (1) heartburn/regurgitation; (2) nausea/vomiting; (3) bloating/abdominal pain; and (4) early satiety/loss of appetite. Five respondent clusters were identified; the largest clusters were primarily early satiety/fullness (44%) and gastroesophageal reflux disease-like symptoms (28%). Two small clusters reflected nausea and vomiting (7%) and a heterogeneous symptom profile (4%). Symptomatic respondents reported significantly more missed work, leisure, and household activity days than asymptomatic respondents (all P Conclusions: Factor analysis separated GI symptoms into groupings reflecting gastroesophageal reflux disease and dyspepsia: early satiety, postprandial fullness, and loss of appetite; bloating and abdominal pain/discomfort; and nausea and vomiting. These upper GI symptoms were associated with significant loss of work and activity days.
Alondra Chamorro - One of the best experts on this subject based on the ideXlab platform.
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development of a management framework for rural roads in developing countries integrating Socioeconomic Impacts
Transportation Research Record, 2009Co-Authors: Alondra Chamorro, Susan L TigheAbstract:During the past decade, considerable efforts have been made to valuate the benefits of investments in rural roads in developing countries. Although the outputs of those studies have led to a global rethinking of traditional road appraisal methods, limited attempts have been made to integrate these findings into the rural road management process. The problem that arises from the analysis is a missing link between the appraisal of the Socioeconomic Impact and the management of rural roads. The main objective of the present study was to develop a methodology that combined all key aspects required for the sustainable management of rural roads in developing countries. For this, social, technical, economic, political, and sustainability aspects must be considered at the different levels of the management process. A case study developed in Chile is presented to illustrate the application of the proposed framework at the strategic and the network levels. From the application it was concluded that it was possible to combine in a practical and integrated tool all key factors affecting the process of management of rural roads in developing countries.
L K Poulsen - One of the best experts on this subject based on the ideXlab platform.
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european symposium on precision medicine in allergy and airways diseases report of the european union parliament symposium october 14 2015
Allergy, 2016Co-Authors: Antonella Muraro, Jean Bousquet, W J Fokkens, Sirpa Pietikainen, D Borrelli, Ioana Agache, V Costigliola, Guy Joos, Valerie J Lund, L K PoulsenAbstract:The European Academy of Allergy and Clinical Immunology (EAACI), the European Rhinologic Society (ERS), and the European Medical Association (EMA) organized, on October 14, 2015, a symposium in the European Parliament in Brussels on Precision Medicine in Allergy and Airways Diseases, hosted by MEP David Borrelli, and with active participation of the EU Commissioner for Health and Food Safety Vytenis Andriukaitis, MEP Sirpa Pietikainen, Chair of the European Parliament Interest Group on Allergy and Asthma, the European Respiratory Society (ERS), the European Federations of Allergy and Airways Diseases Patients Associations (EFA), the Global Allergy and Asthma European Network (Ga2len), Allergic Rhinitis and Its Impact on Asthma (ARIA), and the Respiratory Effectiveness Group (REG). The Socioeconomic Impact of allergies and chronic airways diseases cannot be underestimated, as they represent the most frequently diagnosed chronic noncommunicable diseases in the EU; 30% of the total European population is suffering from allergies and asthma, and more than half are deprived from adequate diagnosis and treatment. Precision medicine represents a novel approach, embracing four key features: personalized care based on molecular, immunologic, and functional endotyping of the disease, with participation of the patient in the decision-making process of therapeutic actions, and considering predictive and preventive aspects of the treatment. Implementation of precision medicine into clinical practice may help to achieve the arrest of the epidemic of allergies and chronic airways diseases. Participants underscored the need for optimal patient care in Europe, supporting joint action plans for disease prevention, patient empowerment, and cost-effective treatment strategies.
