Sodium Fluoride

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Susanne Klutmann - One of the best experts on this subject based on the ideXlab platform.

  • feasibility of 18f Sodium Fluoride pet ct for imaging of atherosclerotic plaque
    The Journal of Nuclear Medicine, 2010
    Co-Authors: Thorsten Derlin, Ulrich Richter, Peter Bannas, Philipp G C Begemann, Ralph Buchert, Janos Mester, Susanne Klutmann
    Abstract:

    UNLABELLED: The aim of this study was to examine the prevalence, distribution, and topographic relationship of vascular (18)F-Sodium Fluoride uptake and arterial calcification in major arteries. METHODS: Image data obtained from 75 patients undergoing whole-body (18)F-Sodium Fluoride PET/CT were evaluated retrospectively. Arterial radiotracer uptake and calcification were analyzed qualitatively and semiquantitatively. RESULTS: (18)F-Sodium Fluoride uptake was observed at 254 sites in 57 (76%) of the 75 study patients, and calcification was observed at 1,930 sites in 63 (84%) of the patients. Colocalization of radiotracer accumulation and calcification could be observed in 223 areas of uptake (88%). However, only 12% of all arterial calcification sites showed increased radiotracer uptake. CONCLUSION: Our data indicate the feasibility of (18)F-Sodium Fluoride PET/CT for the imaging of mineral deposition in arterial wall alterations. (18)F-Sodium Fluoride PET/CT may provide relevant information about the morphologic and functional properties of calcified plaque.

  • feasibility of 18f Sodium Fluoride pet ct for imaging of atherosclerotic plaque
    The Journal of Nuclear Medicine, 2010
    Co-Authors: Thorsten Derlin, Ulrich Richter, Peter Bannas, Philipp G C Begemann, Ralph Buchert, Janos Mester, Susanne Klutmann
    Abstract:

    The aim of this study was to examine the prevalence, distribution, and topographic relationship of vascular 18F-Sodium Fluoride uptake and arterial calcification in major arteries. Methods: Image data obtained from 75 patients undergoing whole-body 18F-Sodium Fluoride PET/CT were evaluated retrospectively. Arterial radiotracer uptake and calcification were analyzed qualitatively and semiquantitatively. Results:18F-Sodium Fluoride uptake was observed at 254 sites in 57 (76%) of the 75 study patients, and calcification was observed at 1,930 sites in 63 (84%) of the patients. Colocalization of radiotracer accumulation and calcification could be observed in 223 areas of uptake (88%). However, only 12% of all arterial calcification sites showed increased radiotracer uptake. Conclusion: Our data indicate the feasibility of 18F-Sodium Fluoride PET/CT for the imaging of mineral deposition in arterial wall alterations. 18F-Sodium Fluoride PET/CT may provide relevant information about the morphologic and functional properties of calcified plaque.

  • Feasibility of 18F-Sodium Fluoride PET/CT for Imaging of Atherosclerotic Plaque
    Journal of nuclear medicine : official publication Society of Nuclear Medicine, 2010
    Co-Authors: Thorsten Derlin, Ulrich Richter, Peter Bannas, Philipp G C Begemann, Ralph Buchert, Janos Mester, Susanne Klutmann
    Abstract:

    The aim of this study was to examine the prevalence, distribution, and topographic relationship of vascular 18F-Sodium Fluoride uptake and arterial calcification in major arteries. Methods: Image data obtained from 75 patients undergoing whole-body 18F-Sodium Fluoride PET/CT were evaluated retrospectively. Arterial radiotracer uptake and calcification were analyzed qualitatively and semiquantitatively. Results:18F-Sodium Fluoride uptake was observed at 254 sites in 57 (76%) of the 75 study patients, and calcification was observed at 1,930 sites in 63 (84%) of the patients. Colocalization of radiotracer accumulation and calcification could be observed in 223 areas of uptake (88%). However, only 12% of all arterial calcification sites showed increased radiotracer uptake. Conclusion: Our data indicate the feasibility of 18F-Sodium Fluoride PET/CT for the imaging of mineral deposition in arterial wall alterations. 18F-Sodium Fluoride PET/CT may provide relevant information about the morphologic and functional properties of calcified plaque.

Thorsten Derlin - One of the best experts on this subject based on the ideXlab platform.

  • feasibility of 18f Sodium Fluoride pet ct for imaging of atherosclerotic plaque
    The Journal of Nuclear Medicine, 2010
    Co-Authors: Thorsten Derlin, Ulrich Richter, Peter Bannas, Philipp G C Begemann, Ralph Buchert, Janos Mester, Susanne Klutmann
    Abstract:

    UNLABELLED: The aim of this study was to examine the prevalence, distribution, and topographic relationship of vascular (18)F-Sodium Fluoride uptake and arterial calcification in major arteries. METHODS: Image data obtained from 75 patients undergoing whole-body (18)F-Sodium Fluoride PET/CT were evaluated retrospectively. Arterial radiotracer uptake and calcification were analyzed qualitatively and semiquantitatively. RESULTS: (18)F-Sodium Fluoride uptake was observed at 254 sites in 57 (76%) of the 75 study patients, and calcification was observed at 1,930 sites in 63 (84%) of the patients. Colocalization of radiotracer accumulation and calcification could be observed in 223 areas of uptake (88%). However, only 12% of all arterial calcification sites showed increased radiotracer uptake. CONCLUSION: Our data indicate the feasibility of (18)F-Sodium Fluoride PET/CT for the imaging of mineral deposition in arterial wall alterations. (18)F-Sodium Fluoride PET/CT may provide relevant information about the morphologic and functional properties of calcified plaque.

  • feasibility of 18f Sodium Fluoride pet ct for imaging of atherosclerotic plaque
    The Journal of Nuclear Medicine, 2010
    Co-Authors: Thorsten Derlin, Ulrich Richter, Peter Bannas, Philipp G C Begemann, Ralph Buchert, Janos Mester, Susanne Klutmann
    Abstract:

    The aim of this study was to examine the prevalence, distribution, and topographic relationship of vascular 18F-Sodium Fluoride uptake and arterial calcification in major arteries. Methods: Image data obtained from 75 patients undergoing whole-body 18F-Sodium Fluoride PET/CT were evaluated retrospectively. Arterial radiotracer uptake and calcification were analyzed qualitatively and semiquantitatively. Results:18F-Sodium Fluoride uptake was observed at 254 sites in 57 (76%) of the 75 study patients, and calcification was observed at 1,930 sites in 63 (84%) of the patients. Colocalization of radiotracer accumulation and calcification could be observed in 223 areas of uptake (88%). However, only 12% of all arterial calcification sites showed increased radiotracer uptake. Conclusion: Our data indicate the feasibility of 18F-Sodium Fluoride PET/CT for the imaging of mineral deposition in arterial wall alterations. 18F-Sodium Fluoride PET/CT may provide relevant information about the morphologic and functional properties of calcified plaque.

  • Feasibility of 18F-Sodium Fluoride PET/CT for Imaging of Atherosclerotic Plaque
    Journal of nuclear medicine : official publication Society of Nuclear Medicine, 2010
    Co-Authors: Thorsten Derlin, Ulrich Richter, Peter Bannas, Philipp G C Begemann, Ralph Buchert, Janos Mester, Susanne Klutmann
    Abstract:

    The aim of this study was to examine the prevalence, distribution, and topographic relationship of vascular 18F-Sodium Fluoride uptake and arterial calcification in major arteries. Methods: Image data obtained from 75 patients undergoing whole-body 18F-Sodium Fluoride PET/CT were evaluated retrospectively. Arterial radiotracer uptake and calcification were analyzed qualitatively and semiquantitatively. Results:18F-Sodium Fluoride uptake was observed at 254 sites in 57 (76%) of the 75 study patients, and calcification was observed at 1,930 sites in 63 (84%) of the patients. Colocalization of radiotracer accumulation and calcification could be observed in 223 areas of uptake (88%). However, only 12% of all arterial calcification sites showed increased radiotracer uptake. Conclusion: Our data indicate the feasibility of 18F-Sodium Fluoride PET/CT for the imaging of mineral deposition in arterial wall alterations. 18F-Sodium Fluoride PET/CT may provide relevant information about the morphologic and functional properties of calcified plaque.

Janos Mester - One of the best experts on this subject based on the ideXlab platform.

  • feasibility of 18f Sodium Fluoride pet ct for imaging of atherosclerotic plaque
    The Journal of Nuclear Medicine, 2010
    Co-Authors: Thorsten Derlin, Ulrich Richter, Peter Bannas, Philipp G C Begemann, Ralph Buchert, Janos Mester, Susanne Klutmann
    Abstract:

    UNLABELLED: The aim of this study was to examine the prevalence, distribution, and topographic relationship of vascular (18)F-Sodium Fluoride uptake and arterial calcification in major arteries. METHODS: Image data obtained from 75 patients undergoing whole-body (18)F-Sodium Fluoride PET/CT were evaluated retrospectively. Arterial radiotracer uptake and calcification were analyzed qualitatively and semiquantitatively. RESULTS: (18)F-Sodium Fluoride uptake was observed at 254 sites in 57 (76%) of the 75 study patients, and calcification was observed at 1,930 sites in 63 (84%) of the patients. Colocalization of radiotracer accumulation and calcification could be observed in 223 areas of uptake (88%). However, only 12% of all arterial calcification sites showed increased radiotracer uptake. CONCLUSION: Our data indicate the feasibility of (18)F-Sodium Fluoride PET/CT for the imaging of mineral deposition in arterial wall alterations. (18)F-Sodium Fluoride PET/CT may provide relevant information about the morphologic and functional properties of calcified plaque.

  • feasibility of 18f Sodium Fluoride pet ct for imaging of atherosclerotic plaque
    The Journal of Nuclear Medicine, 2010
    Co-Authors: Thorsten Derlin, Ulrich Richter, Peter Bannas, Philipp G C Begemann, Ralph Buchert, Janos Mester, Susanne Klutmann
    Abstract:

    The aim of this study was to examine the prevalence, distribution, and topographic relationship of vascular 18F-Sodium Fluoride uptake and arterial calcification in major arteries. Methods: Image data obtained from 75 patients undergoing whole-body 18F-Sodium Fluoride PET/CT were evaluated retrospectively. Arterial radiotracer uptake and calcification were analyzed qualitatively and semiquantitatively. Results:18F-Sodium Fluoride uptake was observed at 254 sites in 57 (76%) of the 75 study patients, and calcification was observed at 1,930 sites in 63 (84%) of the patients. Colocalization of radiotracer accumulation and calcification could be observed in 223 areas of uptake (88%). However, only 12% of all arterial calcification sites showed increased radiotracer uptake. Conclusion: Our data indicate the feasibility of 18F-Sodium Fluoride PET/CT for the imaging of mineral deposition in arterial wall alterations. 18F-Sodium Fluoride PET/CT may provide relevant information about the morphologic and functional properties of calcified plaque.

  • Feasibility of 18F-Sodium Fluoride PET/CT for Imaging of Atherosclerotic Plaque
    Journal of nuclear medicine : official publication Society of Nuclear Medicine, 2010
    Co-Authors: Thorsten Derlin, Ulrich Richter, Peter Bannas, Philipp G C Begemann, Ralph Buchert, Janos Mester, Susanne Klutmann
    Abstract:

    The aim of this study was to examine the prevalence, distribution, and topographic relationship of vascular 18F-Sodium Fluoride uptake and arterial calcification in major arteries. Methods: Image data obtained from 75 patients undergoing whole-body 18F-Sodium Fluoride PET/CT were evaluated retrospectively. Arterial radiotracer uptake and calcification were analyzed qualitatively and semiquantitatively. Results:18F-Sodium Fluoride uptake was observed at 254 sites in 57 (76%) of the 75 study patients, and calcification was observed at 1,930 sites in 63 (84%) of the patients. Colocalization of radiotracer accumulation and calcification could be observed in 223 areas of uptake (88%). However, only 12% of all arterial calcification sites showed increased radiotracer uptake. Conclusion: Our data indicate the feasibility of 18F-Sodium Fluoride PET/CT for the imaging of mineral deposition in arterial wall alterations. 18F-Sodium Fluoride PET/CT may provide relevant information about the morphologic and functional properties of calcified plaque.

Philipp G C Begemann - One of the best experts on this subject based on the ideXlab platform.

  • feasibility of 18f Sodium Fluoride pet ct for imaging of atherosclerotic plaque
    The Journal of Nuclear Medicine, 2010
    Co-Authors: Thorsten Derlin, Ulrich Richter, Peter Bannas, Philipp G C Begemann, Ralph Buchert, Janos Mester, Susanne Klutmann
    Abstract:

    UNLABELLED: The aim of this study was to examine the prevalence, distribution, and topographic relationship of vascular (18)F-Sodium Fluoride uptake and arterial calcification in major arteries. METHODS: Image data obtained from 75 patients undergoing whole-body (18)F-Sodium Fluoride PET/CT were evaluated retrospectively. Arterial radiotracer uptake and calcification were analyzed qualitatively and semiquantitatively. RESULTS: (18)F-Sodium Fluoride uptake was observed at 254 sites in 57 (76%) of the 75 study patients, and calcification was observed at 1,930 sites in 63 (84%) of the patients. Colocalization of radiotracer accumulation and calcification could be observed in 223 areas of uptake (88%). However, only 12% of all arterial calcification sites showed increased radiotracer uptake. CONCLUSION: Our data indicate the feasibility of (18)F-Sodium Fluoride PET/CT for the imaging of mineral deposition in arterial wall alterations. (18)F-Sodium Fluoride PET/CT may provide relevant information about the morphologic and functional properties of calcified plaque.

  • feasibility of 18f Sodium Fluoride pet ct for imaging of atherosclerotic plaque
    The Journal of Nuclear Medicine, 2010
    Co-Authors: Thorsten Derlin, Ulrich Richter, Peter Bannas, Philipp G C Begemann, Ralph Buchert, Janos Mester, Susanne Klutmann
    Abstract:

    The aim of this study was to examine the prevalence, distribution, and topographic relationship of vascular 18F-Sodium Fluoride uptake and arterial calcification in major arteries. Methods: Image data obtained from 75 patients undergoing whole-body 18F-Sodium Fluoride PET/CT were evaluated retrospectively. Arterial radiotracer uptake and calcification were analyzed qualitatively and semiquantitatively. Results:18F-Sodium Fluoride uptake was observed at 254 sites in 57 (76%) of the 75 study patients, and calcification was observed at 1,930 sites in 63 (84%) of the patients. Colocalization of radiotracer accumulation and calcification could be observed in 223 areas of uptake (88%). However, only 12% of all arterial calcification sites showed increased radiotracer uptake. Conclusion: Our data indicate the feasibility of 18F-Sodium Fluoride PET/CT for the imaging of mineral deposition in arterial wall alterations. 18F-Sodium Fluoride PET/CT may provide relevant information about the morphologic and functional properties of calcified plaque.

  • Feasibility of 18F-Sodium Fluoride PET/CT for Imaging of Atherosclerotic Plaque
    Journal of nuclear medicine : official publication Society of Nuclear Medicine, 2010
    Co-Authors: Thorsten Derlin, Ulrich Richter, Peter Bannas, Philipp G C Begemann, Ralph Buchert, Janos Mester, Susanne Klutmann
    Abstract:

    The aim of this study was to examine the prevalence, distribution, and topographic relationship of vascular 18F-Sodium Fluoride uptake and arterial calcification in major arteries. Methods: Image data obtained from 75 patients undergoing whole-body 18F-Sodium Fluoride PET/CT were evaluated retrospectively. Arterial radiotracer uptake and calcification were analyzed qualitatively and semiquantitatively. Results:18F-Sodium Fluoride uptake was observed at 254 sites in 57 (76%) of the 75 study patients, and calcification was observed at 1,930 sites in 63 (84%) of the patients. Colocalization of radiotracer accumulation and calcification could be observed in 223 areas of uptake (88%). However, only 12% of all arterial calcification sites showed increased radiotracer uptake. Conclusion: Our data indicate the feasibility of 18F-Sodium Fluoride PET/CT for the imaging of mineral deposition in arterial wall alterations. 18F-Sodium Fluoride PET/CT may provide relevant information about the morphologic and functional properties of calcified plaque.

Ulrich Richter - One of the best experts on this subject based on the ideXlab platform.

  • feasibility of 18f Sodium Fluoride pet ct for imaging of atherosclerotic plaque
    The Journal of Nuclear Medicine, 2010
    Co-Authors: Thorsten Derlin, Ulrich Richter, Peter Bannas, Philipp G C Begemann, Ralph Buchert, Janos Mester, Susanne Klutmann
    Abstract:

    UNLABELLED: The aim of this study was to examine the prevalence, distribution, and topographic relationship of vascular (18)F-Sodium Fluoride uptake and arterial calcification in major arteries. METHODS: Image data obtained from 75 patients undergoing whole-body (18)F-Sodium Fluoride PET/CT were evaluated retrospectively. Arterial radiotracer uptake and calcification were analyzed qualitatively and semiquantitatively. RESULTS: (18)F-Sodium Fluoride uptake was observed at 254 sites in 57 (76%) of the 75 study patients, and calcification was observed at 1,930 sites in 63 (84%) of the patients. Colocalization of radiotracer accumulation and calcification could be observed in 223 areas of uptake (88%). However, only 12% of all arterial calcification sites showed increased radiotracer uptake. CONCLUSION: Our data indicate the feasibility of (18)F-Sodium Fluoride PET/CT for the imaging of mineral deposition in arterial wall alterations. (18)F-Sodium Fluoride PET/CT may provide relevant information about the morphologic and functional properties of calcified plaque.

  • feasibility of 18f Sodium Fluoride pet ct for imaging of atherosclerotic plaque
    The Journal of Nuclear Medicine, 2010
    Co-Authors: Thorsten Derlin, Ulrich Richter, Peter Bannas, Philipp G C Begemann, Ralph Buchert, Janos Mester, Susanne Klutmann
    Abstract:

    The aim of this study was to examine the prevalence, distribution, and topographic relationship of vascular 18F-Sodium Fluoride uptake and arterial calcification in major arteries. Methods: Image data obtained from 75 patients undergoing whole-body 18F-Sodium Fluoride PET/CT were evaluated retrospectively. Arterial radiotracer uptake and calcification were analyzed qualitatively and semiquantitatively. Results:18F-Sodium Fluoride uptake was observed at 254 sites in 57 (76%) of the 75 study patients, and calcification was observed at 1,930 sites in 63 (84%) of the patients. Colocalization of radiotracer accumulation and calcification could be observed in 223 areas of uptake (88%). However, only 12% of all arterial calcification sites showed increased radiotracer uptake. Conclusion: Our data indicate the feasibility of 18F-Sodium Fluoride PET/CT for the imaging of mineral deposition in arterial wall alterations. 18F-Sodium Fluoride PET/CT may provide relevant information about the morphologic and functional properties of calcified plaque.

  • Feasibility of 18F-Sodium Fluoride PET/CT for Imaging of Atherosclerotic Plaque
    Journal of nuclear medicine : official publication Society of Nuclear Medicine, 2010
    Co-Authors: Thorsten Derlin, Ulrich Richter, Peter Bannas, Philipp G C Begemann, Ralph Buchert, Janos Mester, Susanne Klutmann
    Abstract:

    The aim of this study was to examine the prevalence, distribution, and topographic relationship of vascular 18F-Sodium Fluoride uptake and arterial calcification in major arteries. Methods: Image data obtained from 75 patients undergoing whole-body 18F-Sodium Fluoride PET/CT were evaluated retrospectively. Arterial radiotracer uptake and calcification were analyzed qualitatively and semiquantitatively. Results:18F-Sodium Fluoride uptake was observed at 254 sites in 57 (76%) of the 75 study patients, and calcification was observed at 1,930 sites in 63 (84%) of the patients. Colocalization of radiotracer accumulation and calcification could be observed in 223 areas of uptake (88%). However, only 12% of all arterial calcification sites showed increased radiotracer uptake. Conclusion: Our data indicate the feasibility of 18F-Sodium Fluoride PET/CT for the imaging of mineral deposition in arterial wall alterations. 18F-Sodium Fluoride PET/CT may provide relevant information about the morphologic and functional properties of calcified plaque.