The Experts below are selected from a list of 1053 Experts worldwide ranked by ideXlab platform
Hoyoung Lee - One of the best experts on this subject based on the ideXlab platform.
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comparison of f 18 fdg pet ct findings between pancreatic Solid Pseudopapillary Tumor and pancreatic ductal adenocarcinoma
European Journal of Radiology, 2014Co-Authors: Yong Il Kim, Seok Ki Kim, Jin Chul Paeng, Hoyoung LeeAbstract:a b s t r a c t Objective: Pancreatic Solid Pseudopapillary Tumor (SPT) is a rare benign Tumor. Little data are available on positron emission tomographic/computed tomographic (PET/CT) characteristics of this Tumor. Therefore, we analyzed the metabolic characteristics of SPT using F-18-FDG PET/CT and compared the results with those of pancreatic ductal adenocarcinoma. Methods: We retrospectively reviewed the records of 11 SPT patients and 46 patients with ductal adenocarcinoma. Ten SPT patients had primary Tumors and 1 patient had metastatic SPT. Maximum standardized uptake value (max SUV), mean SUV, metabolic Tumor volume (MTV), total lesion glycolysis (TLG), and Tumor-to-background ratio (TBR) were evaluated. Mann-Whitney U test between pancreatic SPT and ductal adenocarcinoma was performed. In addition, age, gender and Tumor size-adjusted analysis of covariance (ANCOVA) was done between pancreatic SPT and ductal adenocarcinoma. Results: Compared with pancreatic ductal adenocarcinomas, SPTs had significantly higher Tumor size- adjusted MTV and TLG. MTV and TLG values were significantly correlated with T-stage of the SPTs. In 1 SPT patient, metastases in the liver and mesentery were revealed by intense uptake of FDG on F-18-FDG PET/CT, and after PET/CT had suggested the presence of pancreatic SPT. Conclusion: We recommend that SPT be considered when a Solid pancreatic mass with increased FDG metabolism is encountered on PET/CT. F-18-FDG PET/CT may be useful in detecting subtle metastases of
Yong Il Kim - One of the best experts on this subject based on the ideXlab platform.
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comparison of f 18 fdg pet ct findings between pancreatic Solid Pseudopapillary Tumor and pancreatic ductal adenocarcinoma
European Journal of Radiology, 2014Co-Authors: Yong Il Kim, Seok Ki Kim, Jin Chul Paeng, Hoyoung LeeAbstract:a b s t r a c t Objective: Pancreatic Solid Pseudopapillary Tumor (SPT) is a rare benign Tumor. Little data are available on positron emission tomographic/computed tomographic (PET/CT) characteristics of this Tumor. Therefore, we analyzed the metabolic characteristics of SPT using F-18-FDG PET/CT and compared the results with those of pancreatic ductal adenocarcinoma. Methods: We retrospectively reviewed the records of 11 SPT patients and 46 patients with ductal adenocarcinoma. Ten SPT patients had primary Tumors and 1 patient had metastatic SPT. Maximum standardized uptake value (max SUV), mean SUV, metabolic Tumor volume (MTV), total lesion glycolysis (TLG), and Tumor-to-background ratio (TBR) were evaluated. Mann-Whitney U test between pancreatic SPT and ductal adenocarcinoma was performed. In addition, age, gender and Tumor size-adjusted analysis of covariance (ANCOVA) was done between pancreatic SPT and ductal adenocarcinoma. Results: Compared with pancreatic ductal adenocarcinomas, SPTs had significantly higher Tumor size- adjusted MTV and TLG. MTV and TLG values were significantly correlated with T-stage of the SPTs. In 1 SPT patient, metastases in the liver and mesentery were revealed by intense uptake of FDG on F-18-FDG PET/CT, and after PET/CT had suggested the presence of pancreatic SPT. Conclusion: We recommend that SPT be considered when a Solid pancreatic mass with increased FDG metabolism is encountered on PET/CT. F-18-FDG PET/CT may be useful in detecting subtle metastases of
Changjing Zuo - One of the best experts on this subject based on the ideXlab platform.
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fdg pet ct findings of Solid Pseudopapillary Tumor of the pancreas with ct and mri correlation
Clinical Nuclear Medicine, 2013Co-Authors: Aisheng Dong, Yang Wang, Hui Dong, Jian Zhang, Chao Cheng, Changjing ZuoAbstract:PurposeThe aim of this study was to evaluate retrospectively 18F-FDG PET/CT findings of Solid Pseudopapillary Tumor of the pancreas (SPTP).Patients and MethodsFDG PET/CT findings were reviewed in 8 patients with SPTP confirmed by pathology. Early PET/CT scans were performed 1 hour after FDG injectio
Victoria Dappola - One of the best experts on this subject based on the ideXlab platform.
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endoscopic ultrasound guided fine needle aspiration cytology diagnosis of Solid Pseudopapillary Tumor of the pancreas a case report and literature review
World Journal of Gastroenterology, 2007Co-Authors: Charitini Salla, Paschalis Chatzipantelis, Panagiotis Konstantinou, Ioannis Karoumpalis, Akrivi Pantazopoulou, Victoria DappolaAbstract:We describe the clinical, imaging and cytopathological features of Solid Pseudopapillary Tumor of the pancreas (SPTP) diagnosed by endoscopic ultrasound-guided (EUS-guided) fine-needle aspiration (FNA). A 17-year-old woman was admitted to our hospital with complaints of an unexplained episodic abdominal pain for 2 mo and a short history of hypertension in the endocrinology clinic. Clinical laboratory examinations revealed polycystic ovary syndrome, splenomegaly and low serum amylase and carcinoembryonic antigen (CEA) levels. Computed tomography (CT) analysis revealed a mass of the pancreatic tail with Solid and cystic consistency. EUS confirmed the mass, both in body and tail of the pancreas, with distinct borders, which caused dilation of the peripheral part of the pancreatic duct (major diameter 3.7 mm). The patient underwent EUS-FNA. EUS-FNA cytology specimens consisted of single cells and aggregates of uniform malignant cells, forming microadenoid structures, branching, papillary clusters with delicate fibrovascular cores and nuclear overlapping. Naked capillaries were also seen. The nuclei of malignant cells were round or oval, eccentric with fine granular chromatin, small nucleoli and nuclear grooves in some of them. The malignant cells were periodic acid Schiff (PAS)-Alcian blue (+) and immunocytochemically they were vimentin (+), CA 19.9 (+), synaptophysin (+), chromogranin (-), neuro-specific enolase (-), a1-antitrypsin and a1-antichymotrypsin focal positive. Cytologic findings were strongly suggestive of SPTP. Biopsy confirmed the above cytologic diagnosis. EUS-guided FNA diagnosis of SPTP is accurate. EUS findings, cytomorphologic features and immunostains of cell block help distinguish SPTP from pancreatic endocrine Tumors, acinar cell carcinoma and papillary mucinous carcinoma.
Michael W Stanley - One of the best experts on this subject based on the ideXlab platform.
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endoscopic ultrasound guided fine needle aspiration cytology diagnosis of Solid Pseudopapillary Tumor of the pancreas a rare neoplasm of elusive origin but characteristic cytomorphologic features
American Journal of Clinical Pathology, 2004Co-Authors: Ricardo H Bardales, Barbara A Centeno, Shawn J Mallery, Rebecca Lai, Mark Pochapin, Gerardo Guiter, Michael W StanleyAbstract:Clinical histories, endoscopic ultrasound (EUS)guided fine-needle aspiration (FNA) material, and immunohistochemical stains performed on cell block samples of 6 Solid-Pseudopapillary Tumors of the pancreas (SPTPs) were reviewed in the cases of 5 females (13-58 years) and 1 man (57 years); all had abdominal pain. Preliminary cytologic diagnoses at endoscopy included 1 SPTP, 2 low-grade neoplasms, and 3 pancreatic endocrine Tumors. Variable numbers of branching fragments with central capillaries and myxoid stroma were seen in the smears of 5 of 6 cases but were more apparent in the cell block material of all cases. The cells had bland nuclear features and rare grooves. Extensive necrosis was noted in 1 case and rare mitotic figures in 1. SPTPs showed strong cellular immunoreactivity for vimentin and focal weak keratin reactivity. Neuron-specific enolase, α 1 -antitrypsin, and α 1 -antichymotrypsin stains performed in 2 cases were strongly positive. Subsequent surgical resection confirmed all diagnoses. EUS-guided FNA diagnosis of SPTP is accurate. The characteristic branching papillae with myxoid stroma are best seen in cell block slides. Clinical setting, cytomorphologic features, and immunostains of the cell block help distinguish SPTP from pancreatic endocrine Tumors, acinar cell carcinoma, and papillary mucinous carcinoma. Solid-Pseudopapillary Tumor of the pancreas (SPTP) is a rare neoplasm of uncertain origin, often-indolent biologic behavior, and distinctive pathologic features. It constitutes approximately 1% of pancreatic neoplasms and 3% of cystic lesions of the pancreas. 1-3
