The Experts below are selected from a list of 82221 Experts worldwide ranked by ideXlab platform

Thomas Arnebrant - One of the best experts on this subject based on the ideXlab platform.

  • Protein adsorption to Solid Surfaces.
    Trends in Biotechnology, 1991
    Co-Authors: Marie Wahlgren, Thomas Arnebrant
    Abstract:

    The phenomenon of protein adsorption to Solid Surfaces affects the performance of many materials and processes, in areas ranging from medicine to biochemical engineering. Controlling protein adsorption, from solutions of single proteins as well as from more complex mixtures, requires an understanding of the mechanism(s) by which it occurs. This, in turn, entails detailed characterization of both the protein and the Solid surface and identification of those factors controlling the adsorption process.

Stefa Seege - One of the best experts on this subject based on the ideXlab platform.

  • understanding protein adsorption phenomena at Solid Surfaces
    Advances in Colloid and Interface Science, 2011
    Co-Authors: Michael Rabe, Dorinel Verdes, Stefa Seege
    Abstract:

    Protein adsorption at Solid Surfaces plays a key role in many natural processes and has therefore promoted a widespread interest in many research areas. Despite considerable progress in this field there are still widely differing and even contradictive opinions on how to explain the frequently observed phenomena such as structural rearrangements, cooperative adsorption, overshooting adsorption kinetics, or protein aggregation. In this review recent achievements and new perspectives on protein adsorption processes are comprehensively discussed. The main focus is put on commonly postulated mechanistic aspects and their translation into mathematical concepts and model descriptions. Relevant experimental and computational strategies to practically approach the field of protein adsorption mechanisms and their impact on current successes are outlined.

Marie Wahlgren - One of the best experts on this subject based on the ideXlab platform.

  • Protein adsorption to Solid Surfaces.
    Trends in Biotechnology, 1991
    Co-Authors: Marie Wahlgren, Thomas Arnebrant
    Abstract:

    The phenomenon of protein adsorption to Solid Surfaces affects the performance of many materials and processes, in areas ranging from medicine to biochemical engineering. Controlling protein adsorption, from solutions of single proteins as well as from more complex mixtures, requires an understanding of the mechanism(s) by which it occurs. This, in turn, entails detailed characterization of both the protein and the Solid surface and identification of those factors controlling the adsorption process.

Michael Rabe - One of the best experts on this subject based on the ideXlab platform.

  • understanding protein adsorption phenomena at Solid Surfaces
    Advances in Colloid and Interface Science, 2011
    Co-Authors: Michael Rabe, Dorinel Verdes, Stefa Seege
    Abstract:

    Protein adsorption at Solid Surfaces plays a key role in many natural processes and has therefore promoted a widespread interest in many research areas. Despite considerable progress in this field there are still widely differing and even contradictive opinions on how to explain the frequently observed phenomena such as structural rearrangements, cooperative adsorption, overshooting adsorption kinetics, or protein aggregation. In this review recent achievements and new perspectives on protein adsorption processes are comprehensively discussed. The main focus is put on commonly postulated mechanistic aspects and their translation into mathematical concepts and model descriptions. Relevant experimental and computational strategies to practically approach the field of protein adsorption mechanisms and their impact on current successes are outlined.

Jeffrey J. Gray - One of the best experts on this subject based on the ideXlab platform.

  • The interaction of proteins with Solid Surfaces
    Current Opinion in Structural Biology, 2004
    Co-Authors: Jeffrey J. Gray
    Abstract:

    The interaction of proteins with Solid Surfaces is a fundamental phenomenon with implications for nanotechnology, biomaterials and biotechnological processes. Kinetic and thermodynamic studies have long indicated that significant conformational changes may occur as a protein encounters a surface; new techniques are measuring and modeling these changes. Combinatorial and directed evolution techniques have created new peptide sequences that bind specifically to Solid Surfaces, similar to the natural proteins that regulate crystal growth. Modeling efforts capture kinetics and thermodynamics on the colloidal scale, but detailed treatments of atomic structure are still in development and face the usual challenges of protein modeling. Opportunities abound for fundamental discovery, as well as breakthroughs in biomaterials, biotechnology and nanotechnology.