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Wenlong Zhang - One of the best experts on this subject based on the ideXlab platform.

Wang Ling-li - One of the best experts on this subject based on the ideXlab platform.

Han Chun - One of the best experts on this subject based on the ideXlab platform.

Lei Fan - One of the best experts on this subject based on the ideXlab platform.

Hyun-pyo Kim - One of the best experts on this subject based on the ideXlab platform.

  • tyrosinase inhibitory prenylated flavonoids from Sophora flavescens
    Biological & Pharmaceutical Bulletin, 2003
    Co-Authors: Soo Jin Kim, Sam-sik Kang, Kun-ho Son, Hyun Wook Chang, Hyun-pyo Kim
    Abstract:

    For the purpose of the development of a skin-whitening agent, Sophora flavescens was evaluated for tyrosinase inhibitory activity and its active principles were identified following activity-guided isolation. The ethanol extract and dichloromethane fraction from S. flavescens showed significant inhibition of mushroom tyrosinase. From the dichloromethane fraction, three known prenylated flavonoids, Sophoraflavanone G, kuraridin, and kurarinone, were isolated. Compared with kojic acid (IC50=20.5 μM), these compounds possessed more potent tyrosinase inhibitory activity. The IC50 values were 6.6, 0.6, and 6.2 μM for Sophoraflavanone G, kuraridin, and kurarinone, respectively.

  • Minor Constituents from the Roots of Sophora flavescens
    Natural product sciences, 2001
    Co-Authors: Ju-sun Kim, Sang Jun Han, Ji-hye Byun, Sang-woo Yoo, Sam-sik Kang, Kun-ho Son, Hyeun-wook Chang, Hyun-pyo Kim
    Abstract:

    Lupenone, hexadecyl ferulate, (-)-sophocarpine and three isoflavonoids such as genistein, 3'-methoxydaidzein and calycosin were isolated from the roots of Sophora flavescens.