The Experts below are selected from a list of 18 Experts worldwide ranked by ideXlab platform
Ruiz-muñoz María - One of the best experts on this subject based on the ideXlab platform.
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The custom-made foot orthosis using the Central Stabilizer Element: nex concept of Element
2019Co-Authors: Gijón-noguerón Gabriel, Ortega-avila, Ana Belen, Montes-alguacil Jesus, Ruiz-muñoz MaríaAbstract:Foot orthoses have been applied for the management of lower limb disorders, mainly for those who develop foot pain. The Central Stabilizer Element (CSE) is a new Element that contains the midfoot laterally when a plantar insole is manufactured. OBJECTIVES: - To determine the effect on foot pain of adding the Central Stabilizer Element during the manufacturing process of foot orthosis, -- - To describe the proportions of Central Stabilizer Element in terms of width and length of this Element. METHODS: A sample comprising 130 patients (57 males and 73 females) with foot pain was recruited for this study, with the patients having supinated, neutral, pronated and overpronated feet. All the patients received a custom-made foot orthosis with the Central Stabilizer Element. The Central Stabilizer Element was made of resins of polyvinyl chloride, and is a device insert in foot orthosis that contains the midfoot laterally to control pronation and supination movements. Conclusion •The students know how to design the insole. •They know how to match different foot posture with the different types of insoles •We make our decisions based on the scientific evidence foundUniversidad de Málaga. Campus de Excelencia Internacional Andalucía Tech
Alejandro Luquesuarez - One of the best experts on this subject based on the ideXlab platform.
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the effects of custom made foot orthosis using the central Stabilizer Element on foot pain
Prosthetics and Orthotics International, 2015Co-Authors: Gabriel Gijonnogueron, Encarnacion Cortesjeronimo, Jose Antonio Cerveramarin, Esther Diazmohedo, Eva Lopezosareca, Manuel Fernandezsanchez, Alejandro LuquesuarezAbstract:Background:Foot orthoses have been applied for the management of lower limb disorders, mainly for those who develop foot pain. The Central Stabilizer Element (CSE) is a new Element that contains the midfoot laterally when a plantar insole is manufactured.Objectives:To determine the effect on foot pain of adding the Central Stabilizer Element during the manufacturing process of foot orthosis, and to describe the proportions of Central Stabilizer Element in terms of width and length of this Element.Study design:A clinical study.Methods:A sample comprising 130 patients (57 males and 73 females) with foot pain was recruited for this study, with the patients having supinated, neutral, pronated and overpronated feet. All the patients received a custom-made foot orthosis with the Central Stabilizer Element. The Central Stabilizer Element was made of resins of polyvinyl chloride, and is a device insert in foot orthosis that contains the midfoot laterally to control pronation and supination movements. Perceived pa...
Gijón-noguerón Gabriel - One of the best experts on this subject based on the ideXlab platform.
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The custom-made foot orthosis using the Central Stabilizer Element: nex concept of Element
2019Co-Authors: Gijón-noguerón Gabriel, Ortega-avila, Ana Belen, Montes-alguacil Jesus, Ruiz-muñoz MaríaAbstract:Foot orthoses have been applied for the management of lower limb disorders, mainly for those who develop foot pain. The Central Stabilizer Element (CSE) is a new Element that contains the midfoot laterally when a plantar insole is manufactured. OBJECTIVES: - To determine the effect on foot pain of adding the Central Stabilizer Element during the manufacturing process of foot orthosis, -- - To describe the proportions of Central Stabilizer Element in terms of width and length of this Element. METHODS: A sample comprising 130 patients (57 males and 73 females) with foot pain was recruited for this study, with the patients having supinated, neutral, pronated and overpronated feet. All the patients received a custom-made foot orthosis with the Central Stabilizer Element. The Central Stabilizer Element was made of resins of polyvinyl chloride, and is a device insert in foot orthosis that contains the midfoot laterally to control pronation and supination movements. Conclusion •The students know how to design the insole. •They know how to match different foot posture with the different types of insoles •We make our decisions based on the scientific evidence foundUniversidad de Málaga. Campus de Excelencia Internacional Andalucía Tech
Stuart W Peltz - One of the best experts on this subject based on the ideXlab platform.
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characterization of a general Stabilizer Element that blocks deadenylation dependent mrna decay
Journal of Biological Chemistry, 2001Co-Authors: Maria J Ruizechevarria, Raj Munshi, Julie Tomback, Terri Goss Kinzy, Stuart W PeltzAbstract:mRNA degradation is a regulated process that can play an important role in determining the level of expression of specific genes. The rate at which a specific mRNA is degraded depends largely on specific cis-acting sequences located throughout the transcript. cis-Acting deStabilizer sequences that promote increased rates of decay have been identified in several short-lived mRNAs. However, little is known about Elements that promote stability, known as Stabilizer Elements (STEs), and how they function. The work presented here describes the characterization of a STE in the PGK1 transcript. The PGK1 Stabilizer Element (P-STE) has been delineated to a 64-nucleotide sequence from the coding region that can stabilize a chimeric transcript containing the instability Elements from the 3′-untranslated region of the MFA2 transcript. The P-STE is located within the PGK1 coding region and functions when located in the translated portion of the transcript and at a minimum distance from the 3′-untranslated region. These results further support the link between translation and mRNA degradation. A conserved sequence in the TEF1/2 transcript has been identified that also functions as a STE, suggesting that this sequence Element maybe a general stability determinant found in other yeast mRNAs.
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the rna binding protein pub1 modulates the stability of transcripts containing upstream open reading frames
Cell, 2000Co-Authors: Maria J Ruizechevarria, Stuart W PeltzAbstract:The nonsense-mediated mRNA decay (NMD) pathway functions to degrade transcripts containing nonsense codons. Transcripts containing mutations that insert an upstream open reading frame (uORF) in the 5'-UTR are degraded through NMD. However, several naturally occurring uORF-containing transcripts are resistant to NMD. Here we demonstrate that the GCN4 and YAP1 mRNAs, which contain uORFs, harbor a Stabilizer Element (STE) that prevents rapid NMD by interacting with the RNA binding protein Pub1. Conversely, a uORF-containing mRNA that lacks an STE, such as CPA1, is degraded by the NMD pathway. These results indicate that uORFs can play a pivotal role regulating both translation and turnover and that the Pub1p is a critical factor that modulates the stability of uORF-containing transcripts.
Gabriel Gijonnogueron - One of the best experts on this subject based on the ideXlab platform.
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the effects of custom made foot orthosis using the central Stabilizer Element on foot pain
Prosthetics and Orthotics International, 2015Co-Authors: Gabriel Gijonnogueron, Encarnacion Cortesjeronimo, Jose Antonio Cerveramarin, Esther Diazmohedo, Eva Lopezosareca, Manuel Fernandezsanchez, Alejandro LuquesuarezAbstract:Background:Foot orthoses have been applied for the management of lower limb disorders, mainly for those who develop foot pain. The Central Stabilizer Element (CSE) is a new Element that contains the midfoot laterally when a plantar insole is manufactured.Objectives:To determine the effect on foot pain of adding the Central Stabilizer Element during the manufacturing process of foot orthosis, and to describe the proportions of Central Stabilizer Element in terms of width and length of this Element.Study design:A clinical study.Methods:A sample comprising 130 patients (57 males and 73 females) with foot pain was recruited for this study, with the patients having supinated, neutral, pronated and overpronated feet. All the patients received a custom-made foot orthosis with the Central Stabilizer Element. The Central Stabilizer Element was made of resins of polyvinyl chloride, and is a device insert in foot orthosis that contains the midfoot laterally to control pronation and supination movements. Perceived pa...