The Experts below are selected from a list of 19917 Experts worldwide ranked by ideXlab platform
Sudhir Agrawal - One of the best experts on this subject based on the ideXlab platform.
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solid phase Stereoselective Synthesis of 2 o methyl oligoribonucleoside phosphorothioates using nucleoside bicyclic oxazaphospholidines
Bioorganic & Medicinal Chemistry Letters, 1998Co-Authors: Maojun Guo, Radhakrishnan P Iyer, Sudhir AgrawalAbstract:Abstract The use of 2′-OMe-ribonucleoside bicyclic oxazaphospholidines derived from (R)- or (S)-2-pyrrolidinemethanol has enabled the Stereoselective Synthesis of (Rp)-, and (Sp)-2′-O-methyloligoribonucleoside phosphorothioates. Interestingly, higher stereoselectivity (96–98%) was observed in the Synthesis of (Sp)-2′-O-methyl-oligoribonucleoside phosphorothioates compared to that in the case of (Sp)-oligodeoxyribonucleoside phosphorothioates (90%).
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solid phase Stereoselective Synthesis of oligonucleoside phosphorothioates the nucleoside bicyclic oxazaphospholidines as novel synthons
Tetrahedron Letters, 1998Co-Authors: Radhakrishnan P Iyer, Maojun Guo, Sudhir AgrawalAbstract:Abstract The nucleoside bicylic oxazaphospholidine derived from L-, or D-prolinol is a novel synthon with potential for solid-phase Stereoselective Synthesis of oligonucleoside phosphorothioates.
Huw M L Davies - One of the best experts on this subject based on the ideXlab platform.
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Stereoselective Synthesis of highly substituted cyclohexanes by a rhodium carbene initiated domino sequence
Organic Letters, 2015Co-Authors: Brendan T. Parr, Huw M L DaviesAbstract:A Stereoselective Synthesis of cyclohexanes bearing four stereocenters from vinyldiazoacetates and allyl alcohols by a rhodium-carbene initiated domino reaction is described. The reaction cascade features a tandem ylide formation/[2,3]-sigmatropic rearrangement, oxy-Cope rearrangement, and type II carbonyl ene reaction, all of which proceed with a high degree of stereocontrol. The products are routinely isolated with excellent stereocontrol (>97:3 dr, 99% ee).
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Stereoselective Synthesis of Highly Substituted Cyclohexanes by a Rhodium-Carbene Initiated Domino Sequence
2015Co-Authors: Brendan T. Parr, Huw M L DaviesAbstract:A Stereoselective Synthesis of cyclohexanes bearing four stereocenters from vinyldiazoacetates and allyl alcohols by a rhodium-carbene initiated domino reaction is described. The reaction cascade features a tandem ylide formation/[2,3]-sigmatropic rearrangement, oxy-Cope rearrangement, and type II carbonyl ene reaction, all of which proceed with a high degree of stereocontrol. The products are routinely isolated with excellent stereocontrol (>97:3 dr, 99% ee)
Ur H Rehman - One of the best experts on this subject based on the ideXlab platform.
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Stereoselective Synthesis of sordidin the male produced aggregation pheromone of the banana weevil cosmopolites sordidus
Tetrahedron, 2008Co-Authors: Jhillu S. Yadav, Attaluri R. Prasad, Bhaskar K Reddy, Ur H RehmanAbstract:Abstract Stereoselective Synthesis of (1S,3R,5R,7S)-(+)-sordidin, the natural male-produced aggregation pheromone of the banana weevil Cosmopolites sordidus (Germar) starting from 5-benzyloxy-(2E)-pentene-1-ol is described. The key transformations employed in the Synthesis are Sharpless asymmetric epoxidation, Ueno–Stork cyclization, and Jacobsen kinetic resolution.
Radhakrishnan P Iyer - One of the best experts on this subject based on the ideXlab platform.
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solid phase Stereoselective Synthesis of 2 o methyl oligoribonucleoside phosphorothioates using nucleoside bicyclic oxazaphospholidines
Bioorganic & Medicinal Chemistry Letters, 1998Co-Authors: Maojun Guo, Radhakrishnan P Iyer, Sudhir AgrawalAbstract:Abstract The use of 2′-OMe-ribonucleoside bicyclic oxazaphospholidines derived from (R)- or (S)-2-pyrrolidinemethanol has enabled the Stereoselective Synthesis of (Rp)-, and (Sp)-2′-O-methyloligoribonucleoside phosphorothioates. Interestingly, higher stereoselectivity (96–98%) was observed in the Synthesis of (Sp)-2′-O-methyl-oligoribonucleoside phosphorothioates compared to that in the case of (Sp)-oligodeoxyribonucleoside phosphorothioates (90%).
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solid phase Stereoselective Synthesis of oligonucleoside phosphorothioates the nucleoside bicyclic oxazaphospholidines as novel synthons
Tetrahedron Letters, 1998Co-Authors: Radhakrishnan P Iyer, Maojun Guo, Sudhir AgrawalAbstract:Abstract The nucleoside bicylic oxazaphospholidine derived from L-, or D-prolinol is a novel synthon with potential for solid-phase Stereoselective Synthesis of oligonucleoside phosphorothioates.
Maojun Guo - One of the best experts on this subject based on the ideXlab platform.
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solid phase Stereoselective Synthesis of 2 o methyl oligoribonucleoside phosphorothioates using nucleoside bicyclic oxazaphospholidines
Bioorganic & Medicinal Chemistry Letters, 1998Co-Authors: Maojun Guo, Radhakrishnan P Iyer, Sudhir AgrawalAbstract:Abstract The use of 2′-OMe-ribonucleoside bicyclic oxazaphospholidines derived from (R)- or (S)-2-pyrrolidinemethanol has enabled the Stereoselective Synthesis of (Rp)-, and (Sp)-2′-O-methyloligoribonucleoside phosphorothioates. Interestingly, higher stereoselectivity (96–98%) was observed in the Synthesis of (Sp)-2′-O-methyl-oligoribonucleoside phosphorothioates compared to that in the case of (Sp)-oligodeoxyribonucleoside phosphorothioates (90%).
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solid phase Stereoselective Synthesis of oligonucleoside phosphorothioates the nucleoside bicyclic oxazaphospholidines as novel synthons
Tetrahedron Letters, 1998Co-Authors: Radhakrishnan P Iyer, Maojun Guo, Sudhir AgrawalAbstract:Abstract The nucleoside bicylic oxazaphospholidine derived from L-, or D-prolinol is a novel synthon with potential for solid-phase Stereoselective Synthesis of oligonucleoside phosphorothioates.
