The Experts below are selected from a list of 4860 Experts worldwide ranked by ideXlab platform
Xiaomei Wang - One of the best experts on this subject based on the ideXlab platform.
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Effect of irradiation on parathyroid hormone PTH(1–34) coated on a novel transdermal microprojection delivery system to produce a Sterile Product—adhesive compatibility
Journal of Pharmaceutical Sciences, 2010Co-Authors: Mahmoud Ameri, Xiaomei WangAbstract:Abstract Terminal sterilization via γ‐irradiation or e‐beam and aseptic processing were evaluated as a means to manufacture the Sterile Product of parathyroid hormone 1–34 coated on a novel transdermal microprojection delivery system. The main difference of the two methods is the inclusion and exclusion of the coated formulation for irradiation during terminal sterilization and aseptic processing, respectively. Both γ‐irradiation and e‐beam of the final Product resulted in increased PTH(1–34) oxidation, which could be reduced by lowering the irradiation dose or the irradiation temperature. Minimizing moisture and oxygen levels inside the primary packaging could effectively limit PTH oxidation to
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effect of irradiation on parathyroid hormone pth 1 34 coated on a novel transdermal microprojection delivery system to produce a Sterile Product adhesive compatibility
Journal of Pharmaceutical Sciences, 2010Co-Authors: Mahmoud Ameri, Xiaomei Wang, Yuhfun MaaAbstract:Abstract Terminal sterilization via γ‐irradiation or e‐beam and aseptic processing were evaluated as a means to manufacture the Sterile Product of parathyroid hormone 1–34 coated on a novel transdermal microprojection delivery system. The main difference of the two methods is the inclusion and exclusion of the coated formulation for irradiation during terminal sterilization and aseptic processing, respectively. Both γ‐irradiation and e‐beam of the final Product resulted in increased PTH(1–34) oxidation, which could be reduced by lowering the irradiation dose or the irradiation temperature. Minimizing moisture and oxygen levels inside the primary packaging could effectively limit PTH oxidation to
Mahmoud Ameri - One of the best experts on this subject based on the ideXlab platform.
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Effect of irradiation on parathyroid hormone PTH(1–34) coated on a novel transdermal microprojection delivery system to produce a Sterile Product—adhesive compatibility
Journal of Pharmaceutical Sciences, 2010Co-Authors: Mahmoud Ameri, Xiaomei WangAbstract:Abstract Terminal sterilization via γ‐irradiation or e‐beam and aseptic processing were evaluated as a means to manufacture the Sterile Product of parathyroid hormone 1–34 coated on a novel transdermal microprojection delivery system. The main difference of the two methods is the inclusion and exclusion of the coated formulation for irradiation during terminal sterilization and aseptic processing, respectively. Both γ‐irradiation and e‐beam of the final Product resulted in increased PTH(1–34) oxidation, which could be reduced by lowering the irradiation dose or the irradiation temperature. Minimizing moisture and oxygen levels inside the primary packaging could effectively limit PTH oxidation to
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effect of irradiation on parathyroid hormone pth 1 34 coated on a novel transdermal microprojection delivery system to produce a Sterile Product adhesive compatibility
Journal of Pharmaceutical Sciences, 2010Co-Authors: Mahmoud Ameri, Xiaomei Wang, Yuhfun MaaAbstract:Abstract Terminal sterilization via γ‐irradiation or e‐beam and aseptic processing were evaluated as a means to manufacture the Sterile Product of parathyroid hormone 1–34 coated on a novel transdermal microprojection delivery system. The main difference of the two methods is the inclusion and exclusion of the coated formulation for irradiation during terminal sterilization and aseptic processing, respectively. Both γ‐irradiation and e‐beam of the final Product resulted in increased PTH(1–34) oxidation, which could be reduced by lowering the irradiation dose or the irradiation temperature. Minimizing moisture and oxygen levels inside the primary packaging could effectively limit PTH oxidation to
Yuhfun Maa - One of the best experts on this subject based on the ideXlab platform.
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effect of irradiation on parathyroid hormone pth 1 34 coated on a novel transdermal microprojection delivery system to produce a Sterile Product adhesive compatibility
Journal of Pharmaceutical Sciences, 2010Co-Authors: Mahmoud Ameri, Xiaomei Wang, Yuhfun MaaAbstract:Abstract Terminal sterilization via γ‐irradiation or e‐beam and aseptic processing were evaluated as a means to manufacture the Sterile Product of parathyroid hormone 1–34 coated on a novel transdermal microprojection delivery system. The main difference of the two methods is the inclusion and exclusion of the coated formulation for irradiation during terminal sterilization and aseptic processing, respectively. Both γ‐irradiation and e‐beam of the final Product resulted in increased PTH(1–34) oxidation, which could be reduced by lowering the irradiation dose or the irradiation temperature. Minimizing moisture and oxygen levels inside the primary packaging could effectively limit PTH oxidation to
Gordon L Robertson - One of the best experts on this subject based on the ideXlab platform.
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ultrahigh temperature treatment uht aseptic packaging
Encyclopedia of Dairy Sciences, 2015Co-Authors: Gordon L RobertsonAbstract:Aseptic packaging involves the filling of a commercially Sterile Product into Sterile containers under Sterile conditions and sealing the containers so that reinfection is prevented. Over 35 billion liters of milk Products are aseptically packaged annually. The three main sterilization processes for packaging materials involving radiation, heat, and chemical treatments are discussed. The four main categories of aseptic packaging systems (cartons, plastic bottles, sachets and pouches, and cups) and their major features and characteristics are described.
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heat treatment of milk ultra high temperature treatment uht aseptic packaging
Encyclopedia of Dairy Sciences (Second Edition), 2011Co-Authors: Gordon L RobertsonAbstract:Aseptic packaging is the filling of a commercially Sterile Product into Sterile containers under Sterile conditions and sealing the containers so that reinfection is prevented. The three main processes used commercially, either individually or in combination, to sterilize packaging materials prior to aseptic filling are irradiation (gamma rays, pulsed light, UV lasers, or plasma), heat (either steam or dry heat), and chemical treatments (either hydrogen peroxide or peroxyacetic acid). Packaging materials for aseptic packaging are composed of either paperboard laminates or plastics. Four major categories of aseptic packaging systems are available for dairy Products: cartons, plastic bottles, sachets and pouches (including bag-in-box), and plastic cups. Their major features and characteristics are described. Finally, integrity testing of aseptic packages is discussed, including recent developments in nondestructive or noninvasive methods for assessing package integrity.
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Heat Treatment of Milk | Ultra-High Temperature Treatment (UHT): Aseptic Packaging
Encyclopedia of Dairy Sciences, 2011Co-Authors: Gordon L RobertsonAbstract:Aseptic packaging is the filling of a commercially Sterile Product into Sterile containers under Sterile conditions and sealing the containers so that reinfection is prevented. The three main processes used commercially, either individually or in combination, to sterilize packaging materials prior to aseptic filling are irradiation (gamma rays, pulsed light, UV lasers, or plasma), heat (either steam or dry heat), and chemical treatments (either hydrogen peroxide or peroxyacetic acid). Packaging materials for aseptic packaging are composed of either paperboard laminates or plastics. Four major categories of aseptic packaging systems are available for dairy Products: cartons, plastic bottles, sachets and pouches (including bag-in-box), and plastic cups. Their major features and characteristics are described. Finally, integrity testing of aseptic packages is discussed, including recent developments in nondestructive or noninvasive methods for assessing package integrity.
Mohammed M Farid - One of the best experts on this subject based on the ideXlab platform.
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Pressure assisted thermal sterilization
Food and Bioproducts Processing, 2008Co-Authors: Sajith K. Wimalaratne, Mohammed M FaridAbstract:Abstract High pressure processing (HPP) can inactivate various types of microorganisms in their vegetative form. However, spores can be resistant to pressures as high as 1000 MPa, which in the absence of heat limits the application of HPP to pasteurization only. A new technology has been recently developed to generate mild pressure by heating the treated liquid food in enclosure. This technology was examined for its ability to inactivate spore forming bacteria (Bacillus cereus and Geobacillus stearothermophilus) to produce a Sterile Product which retained its original organoleptic characteristics. Results shows that this pressure assisted thermal sterilization process could decrease the decimal reduction time (D-value) and hence, reduce the sterilization temperature significantly. The mild pressure generated assisted spores to germinate allowing the heat to inactivate the germinated spores. Vegetative microorganisms (Saccharomyces cerevisiae and Escherichia coli) were also tested using the technology. However, the effect of this mild pressure on the inactivation was found insignificant.