The Experts below are selected from a list of 408 Experts worldwide ranked by ideXlab platform

Sergio Paoletti - One of the best experts on this subject based on the ideXlab platform.

  • terminal sterilization of bisgma tegdma thermoset materials and their bioactive surfaces by supercritical co2
    Biomacromolecules, 2012
    Co-Authors: Ivan Donati, Monica Benincasa, Mariepierre Foulc, Gianluca Turco, Dario Solinas, Sara Spilimbergo, Ireneo Kikic, Mila Toppazzini, Sergio Paoletti
    Abstract:

    The development of biomaterials endowed with bioactive features relies on a simultaneous insight into a proper terminal sterilization process. FDA recommendations on Sterility of biomaterials are very strict: a Sterility Assurance Level (SAL) of 10–6 must be guaranteed for biomaterials to be used in human implants. In the present work, we have explored the potential of supercritical CO2 (scCO2) in the presence of H2O2 as a low-temperature sterilization process for thermoset materials and their bioactive surfaces. Different conditions allowing for terminal sterilization have been screened and a treatment time–amount of H2O2 relationship proposed. The selected terminal sterilization conditions did not notably modify the mechanical properties of the thermoset nor of their fiber-reinforced composites. This was confirmed by μCT analyses performed prior to and after the treatment. On the contrary, terminal sterilization in the presence of H2O2 induced a slight decrease in the surface hardness. The treatment of ...

Ivan Donati - One of the best experts on this subject based on the ideXlab platform.

  • terminal sterilization of bisgma tegdma thermoset materials and their bioactive surfaces by supercritical co2
    Biomacromolecules, 2012
    Co-Authors: Ivan Donati, Monica Benincasa, Mariepierre Foulc, Gianluca Turco, Dario Solinas, Sara Spilimbergo, Ireneo Kikic, Mila Toppazzini, Sergio Paoletti
    Abstract:

    The development of biomaterials endowed with bioactive features relies on a simultaneous insight into a proper terminal sterilization process. FDA recommendations on Sterility of biomaterials are very strict: a Sterility Assurance Level (SAL) of 10–6 must be guaranteed for biomaterials to be used in human implants. In the present work, we have explored the potential of supercritical CO2 (scCO2) in the presence of H2O2 as a low-temperature sterilization process for thermoset materials and their bioactive surfaces. Different conditions allowing for terminal sterilization have been screened and a treatment time–amount of H2O2 relationship proposed. The selected terminal sterilization conditions did not notably modify the mechanical properties of the thermoset nor of their fiber-reinforced composites. This was confirmed by μCT analyses performed prior to and after the treatment. On the contrary, terminal sterilization in the presence of H2O2 induced a slight decrease in the surface hardness. The treatment of ...

Mila Toppazzini - One of the best experts on this subject based on the ideXlab platform.

  • terminal sterilization of bisgma tegdma thermoset materials and their bioactive surfaces by supercritical co2
    Biomacromolecules, 2012
    Co-Authors: Ivan Donati, Monica Benincasa, Mariepierre Foulc, Gianluca Turco, Dario Solinas, Sara Spilimbergo, Ireneo Kikic, Mila Toppazzini, Sergio Paoletti
    Abstract:

    The development of biomaterials endowed with bioactive features relies on a simultaneous insight into a proper terminal sterilization process. FDA recommendations on Sterility of biomaterials are very strict: a Sterility Assurance Level (SAL) of 10–6 must be guaranteed for biomaterials to be used in human implants. In the present work, we have explored the potential of supercritical CO2 (scCO2) in the presence of H2O2 as a low-temperature sterilization process for thermoset materials and their bioactive surfaces. Different conditions allowing for terminal sterilization have been screened and a treatment time–amount of H2O2 relationship proposed. The selected terminal sterilization conditions did not notably modify the mechanical properties of the thermoset nor of their fiber-reinforced composites. This was confirmed by μCT analyses performed prior to and after the treatment. On the contrary, terminal sterilization in the presence of H2O2 induced a slight decrease in the surface hardness. The treatment of ...

Ireneo Kikic - One of the best experts on this subject based on the ideXlab platform.

  • terminal sterilization of bisgma tegdma thermoset materials and their bioactive surfaces by supercritical co2
    Biomacromolecules, 2012
    Co-Authors: Ivan Donati, Monica Benincasa, Mariepierre Foulc, Gianluca Turco, Dario Solinas, Sara Spilimbergo, Ireneo Kikic, Mila Toppazzini, Sergio Paoletti
    Abstract:

    The development of biomaterials endowed with bioactive features relies on a simultaneous insight into a proper terminal sterilization process. FDA recommendations on Sterility of biomaterials are very strict: a Sterility Assurance Level (SAL) of 10–6 must be guaranteed for biomaterials to be used in human implants. In the present work, we have explored the potential of supercritical CO2 (scCO2) in the presence of H2O2 as a low-temperature sterilization process for thermoset materials and their bioactive surfaces. Different conditions allowing for terminal sterilization have been screened and a treatment time–amount of H2O2 relationship proposed. The selected terminal sterilization conditions did not notably modify the mechanical properties of the thermoset nor of their fiber-reinforced composites. This was confirmed by μCT analyses performed prior to and after the treatment. On the contrary, terminal sterilization in the presence of H2O2 induced a slight decrease in the surface hardness. The treatment of ...

Sara Spilimbergo - One of the best experts on this subject based on the ideXlab platform.

  • terminal sterilization of bisgma tegdma thermoset materials and their bioactive surfaces by supercritical co2
    Biomacromolecules, 2012
    Co-Authors: Ivan Donati, Monica Benincasa, Mariepierre Foulc, Gianluca Turco, Dario Solinas, Sara Spilimbergo, Ireneo Kikic, Mila Toppazzini, Sergio Paoletti
    Abstract:

    The development of biomaterials endowed with bioactive features relies on a simultaneous insight into a proper terminal sterilization process. FDA recommendations on Sterility of biomaterials are very strict: a Sterility Assurance Level (SAL) of 10–6 must be guaranteed for biomaterials to be used in human implants. In the present work, we have explored the potential of supercritical CO2 (scCO2) in the presence of H2O2 as a low-temperature sterilization process for thermoset materials and their bioactive surfaces. Different conditions allowing for terminal sterilization have been screened and a treatment time–amount of H2O2 relationship proposed. The selected terminal sterilization conditions did not notably modify the mechanical properties of the thermoset nor of their fiber-reinforced composites. This was confirmed by μCT analyses performed prior to and after the treatment. On the contrary, terminal sterilization in the presence of H2O2 induced a slight decrease in the surface hardness. The treatment of ...