The Experts below are selected from a list of 303 Experts worldwide ranked by ideXlab platform

Colin E Sullivan - One of the best experts on this subject based on the ideXlab platform.

  • Snoring and Stertor are associated with more sleep disturbance than apneas and hypopneas in pediatric SDB
    Sleep and Breathing, 2019
    Co-Authors: Mark B. Norman, Karen A Waters, Henley C. Harrison, Colin E Sullivan
    Abstract:

    Purpose Polysomnography is not recommended for children at home and does not adequately capture partial upper airway obstruction (snoring and Stertor), the dominant pathology in pediatric sleep-disordered breathing. New methods are required for assessment. Aims were to assess sleep disruption linked to partial upper airway obstruction and to evaluate unattended Sonomat use in a large group of children at home. Methods Children with suspected obstructive sleep apnea (OSA) had a single home-based Sonomat recording ( n  = 231). Quantification of breath sound recordings allowed identification of snoring, Stertor, and apneas/hypopneas. Movement signals were used to measure quiescent (sleep) time and sleep disruption. Results Successful recordings occurred in 213 (92%) and 113 (53%) had no OSA whereas only 11 (5%) had no partial obstruction. Snore/Stertor occurred more frequently (15.3 [5.4, 30.1] events/h) and for a longer total duration (69.9 min [15.7, 140.9]) than obstructive/mixed apneas and hypopneas (0.8 [0.0, 4.7] events/h, 1.2 min [0.0, 8.5]); both p  

  • snoring and Stertor are associated with more sleep disturbance than apneas and hypopneas in pediatric sdb
    Sleep and Breathing, 2019
    Co-Authors: Mark Norman, Henley Harrison, Karen A Waters, Colin E Sullivan
    Abstract:

    Polysomnography is not recommended for children at home and does not adequately capture partial upper airway obstruction (snoring and Stertor), the dominant pathology in pediatric sleep-disordered breathing. New methods are required for assessment. Aims were to assess sleep disruption linked to partial upper airway obstruction and to evaluate unattended Sonomat use in a large group of children at home. Children with suspected obstructive sleep apnea (OSA) had a single home-based Sonomat recording (n = 231). Quantification of breath sound recordings allowed identification of snoring, Stertor, and apneas/hypopneas. Movement signals were used to measure quiescent (sleep) time and sleep disruption. Successful recordings occurred in 213 (92%) and 113 (53%) had no OSA whereas only 11 (5%) had no partial obstruction. Snore/Stertor occurred more frequently (15.3 [5.4, 30.1] events/h) and for a longer total duration (69.9 min [15.7, 140.9]) than obstructive/mixed apneas and hypopneas (0.8 [0.0, 4.7] events/h, 1.2 min [0.0, 8.5]); both p < 0.0001. Many non-OSA children had more partial obstruction than those with OSA. Most intervals between snore and Stertor runs were < 60 s (79% and 61% respectively), indicating that they occur in clusters. Of 14,145 respiratory-induced movement arousals, 70% were preceded by runs of snore/Stertor with the remainder associated with apneas/hypopneas. Runs of snoring and Stertor occur much more frequently than obstructive apneas/hypopneas and are associated with a greater degree of sleep disruption. Children with and without OSA are frequently indistinguishable regarding the amount, frequency, and the degree of sleep disturbance caused by snoring and Stertor.

  • Snoring and Stertor are associated with more sleep disturbance than apneas and hypopneas in pediatric SDB.
    Sleep and Breathing, 2019
    Co-Authors: Mark Norman, Karen A Waters, Henley C. Harrison, Colin E Sullivan
    Abstract:

    Polysomnography is not recommended for children at home and does not adequately capture partial upper airway obstruction (snoring and Stertor), the dominant pathology in pediatric sleep-disordered breathing. New methods are required for assessment. Aims were to assess sleep disruption linked to partial upper airway obstruction and to evaluate unattended Sonomat use in a large group of children at home. Children with suspected obstructive sleep apnea (OSA) had a single home-based Sonomat recording (n = 231). Quantification of breath sound recordings allowed identification of snoring, Stertor, and apneas/hypopneas. Movement signals were used to measure quiescent (sleep) time and sleep disruption. Successful recordings occurred in 213 (92%) and 113 (53%) had no OSA whereas only 11 (5%) had no partial obstruction. Snore/Stertor occurred more frequently (15.3 [5.4, 30.1] events/h) and for a longer total duration (69.9 min [15.7, 140.9]) than obstructive/mixed apneas and hypopneas (0.8 [0.0, 4.7] events/h, 1.2 min [0.0, 8.5]); both p 

  • Validation of the Sonomat Against PSG and Quantitative Measurement of Partial Upper Airway Obstruction in Children With Sleep-Disordered Breathing.
    Sleep, 2017
    Co-Authors: Mark Norman, Karen A Waters, S. Pithers, Arthur Teng, Colin E Sullivan
    Abstract:

    Study Objectives: To validate the Sonomat against polysomnography (PSG) metrics in children and to objectively measure snoring and Stertor to produce a quantitative indicator of partial upper airway obstruction that accurately reflects the pathology of pediatric sleep-disordered breathing (SDB). Methods: Simultaneous PSG and Sonomat recordings were performed in 76 children (46 male, age 5.8 ± 2.8, BMI = 18.5 ± 3.8 kg/m2). Sleep time, individual respiratory events and the apnea/hypopnea index (AHI) were compared. Obstructed breathing sounds were measured from the unobtrusive non-contact experimental device. Results: There was no significant difference in total sleep time (TST), respiratory events or AHI values, the latter over-estimated by 0.3 events hr-1 by the Sonomat. Poor signal quality was minimal and gender, BMI, and body position did not adversely influence event detection. Obstructive and central events were classified correctly. The number of runs and duration of snoring (13 399 events, 20% TST) and Stertor (5748 events, 24% TST) were an order of magnitude greater than respiratory events (1367 events, 1% TST). Many children defined as normal by PSG had just as many or more runs of snoring and Stertor as those with mild, moderate and severe obstructive sleep apnea (OSA). Conclusions: The Sonomat accurately diagnoses SDB in children using current metrics. In addition, it permits quantification of partial airway obstruction that can be used to better describe pediatric SDB. Its non-contact design makes it ideal for use in children.

Karen A Waters - One of the best experts on this subject based on the ideXlab platform.

  • TcCO2 changes correlate with partial obstruction in children suspected of sleep disordered breathing.
    Pediatric Pulmonology, 2020
    Co-Authors: Bebe D'souza, Mark Norman, Colin Edward Sullivan, Karen A Waters
    Abstract:

    INTRODUCTION Paediatric sleep disordered breathing (SDB) is characterised by long periods of partial upper airway obstruction (UAO) with low apnea-hypopnea indices (AHI). By measuring snoring and Stertor, Sonomat studies allow quantification of these periods of partial UAO. AIM To determine whether transcutaneous CO2 (TcCO2 ) levels correlate with increasing levels of partial UAO and to examine patterns of ΔTcCo2 in the transitions from (1) wakefulness to sleep and (2) NREM to REM sleep. METHODS This was a retrospective review of sleep studies in 7 asymptomatic controls aged 7-12 years and 62 symptomatic children with suspected SDB and no comorbidities, aged 2-13 years. Both groups underwent overnight polysomnography, including continuous TcCO2 , at one of two paediatric hospitals in Sydney. Changes in carbon dioxide levels between wake to NREM (sleep onset) and NREM to REM sleep were evaluated using an all-night TcCO2 trace time-linked to a hypnogram. Paired Sonomat recordings were used to quantify periods of UAO in the symptomatic group. RESULTS The ΔTcCO2 at sleep onset was greater in SDB children than controls and ΔTcCO2 with sleep onset correlated with the duration of partial obstruction (r=0.60, p

  • Snoring and Stertor are associated with more sleep disturbance than apneas and hypopneas in pediatric SDB
    Sleep and Breathing, 2019
    Co-Authors: Mark B. Norman, Karen A Waters, Henley C. Harrison, Colin E Sullivan
    Abstract:

    Purpose Polysomnography is not recommended for children at home and does not adequately capture partial upper airway obstruction (snoring and Stertor), the dominant pathology in pediatric sleep-disordered breathing. New methods are required for assessment. Aims were to assess sleep disruption linked to partial upper airway obstruction and to evaluate unattended Sonomat use in a large group of children at home. Methods Children with suspected obstructive sleep apnea (OSA) had a single home-based Sonomat recording ( n  = 231). Quantification of breath sound recordings allowed identification of snoring, Stertor, and apneas/hypopneas. Movement signals were used to measure quiescent (sleep) time and sleep disruption. Results Successful recordings occurred in 213 (92%) and 113 (53%) had no OSA whereas only 11 (5%) had no partial obstruction. Snore/Stertor occurred more frequently (15.3 [5.4, 30.1] events/h) and for a longer total duration (69.9 min [15.7, 140.9]) than obstructive/mixed apneas and hypopneas (0.8 [0.0, 4.7] events/h, 1.2 min [0.0, 8.5]); both p  

  • snoring and Stertor are associated with more sleep disturbance than apneas and hypopneas in pediatric sdb
    Sleep and Breathing, 2019
    Co-Authors: Mark Norman, Henley Harrison, Karen A Waters, Colin E Sullivan
    Abstract:

    Polysomnography is not recommended for children at home and does not adequately capture partial upper airway obstruction (snoring and Stertor), the dominant pathology in pediatric sleep-disordered breathing. New methods are required for assessment. Aims were to assess sleep disruption linked to partial upper airway obstruction and to evaluate unattended Sonomat use in a large group of children at home. Children with suspected obstructive sleep apnea (OSA) had a single home-based Sonomat recording (n = 231). Quantification of breath sound recordings allowed identification of snoring, Stertor, and apneas/hypopneas. Movement signals were used to measure quiescent (sleep) time and sleep disruption. Successful recordings occurred in 213 (92%) and 113 (53%) had no OSA whereas only 11 (5%) had no partial obstruction. Snore/Stertor occurred more frequently (15.3 [5.4, 30.1] events/h) and for a longer total duration (69.9 min [15.7, 140.9]) than obstructive/mixed apneas and hypopneas (0.8 [0.0, 4.7] events/h, 1.2 min [0.0, 8.5]); both p < 0.0001. Many non-OSA children had more partial obstruction than those with OSA. Most intervals between snore and Stertor runs were < 60 s (79% and 61% respectively), indicating that they occur in clusters. Of 14,145 respiratory-induced movement arousals, 70% were preceded by runs of snore/Stertor with the remainder associated with apneas/hypopneas. Runs of snoring and Stertor occur much more frequently than obstructive apneas/hypopneas and are associated with a greater degree of sleep disruption. Children with and without OSA are frequently indistinguishable regarding the amount, frequency, and the degree of sleep disturbance caused by snoring and Stertor.

  • Snoring and Stertor are associated with more sleep disturbance than apneas and hypopneas in pediatric SDB.
    Sleep and Breathing, 2019
    Co-Authors: Mark Norman, Karen A Waters, Henley C. Harrison, Colin E Sullivan
    Abstract:

    Polysomnography is not recommended for children at home and does not adequately capture partial upper airway obstruction (snoring and Stertor), the dominant pathology in pediatric sleep-disordered breathing. New methods are required for assessment. Aims were to assess sleep disruption linked to partial upper airway obstruction and to evaluate unattended Sonomat use in a large group of children at home. Children with suspected obstructive sleep apnea (OSA) had a single home-based Sonomat recording (n = 231). Quantification of breath sound recordings allowed identification of snoring, Stertor, and apneas/hypopneas. Movement signals were used to measure quiescent (sleep) time and sleep disruption. Successful recordings occurred in 213 (92%) and 113 (53%) had no OSA whereas only 11 (5%) had no partial obstruction. Snore/Stertor occurred more frequently (15.3 [5.4, 30.1] events/h) and for a longer total duration (69.9 min [15.7, 140.9]) than obstructive/mixed apneas and hypopneas (0.8 [0.0, 4.7] events/h, 1.2 min [0.0, 8.5]); both p 

  • Validation of the Sonomat Against PSG and Quantitative Measurement of Partial Upper Airway Obstruction in Children With Sleep-Disordered Breathing.
    Sleep, 2017
    Co-Authors: Mark Norman, Karen A Waters, S. Pithers, Arthur Teng, Colin E Sullivan
    Abstract:

    Study Objectives: To validate the Sonomat against polysomnography (PSG) metrics in children and to objectively measure snoring and Stertor to produce a quantitative indicator of partial upper airway obstruction that accurately reflects the pathology of pediatric sleep-disordered breathing (SDB). Methods: Simultaneous PSG and Sonomat recordings were performed in 76 children (46 male, age 5.8 ± 2.8, BMI = 18.5 ± 3.8 kg/m2). Sleep time, individual respiratory events and the apnea/hypopnea index (AHI) were compared. Obstructed breathing sounds were measured from the unobtrusive non-contact experimental device. Results: There was no significant difference in total sleep time (TST), respiratory events or AHI values, the latter over-estimated by 0.3 events hr-1 by the Sonomat. Poor signal quality was minimal and gender, BMI, and body position did not adversely influence event detection. Obstructive and central events were classified correctly. The number of runs and duration of snoring (13 399 events, 20% TST) and Stertor (5748 events, 24% TST) were an order of magnitude greater than respiratory events (1367 events, 1% TST). Many children defined as normal by PSG had just as many or more runs of snoring and Stertor as those with mild, moderate and severe obstructive sleep apnea (OSA). Conclusions: The Sonomat accurately diagnoses SDB in children using current metrics. In addition, it permits quantification of partial airway obstruction that can be used to better describe pediatric SDB. Its non-contact design makes it ideal for use in children.

Mark Norman - One of the best experts on this subject based on the ideXlab platform.

  • TcCO2 changes correlate with partial obstruction in children suspected of sleep disordered breathing.
    Pediatric Pulmonology, 2020
    Co-Authors: Bebe D'souza, Mark Norman, Colin Edward Sullivan, Karen A Waters
    Abstract:

    INTRODUCTION Paediatric sleep disordered breathing (SDB) is characterised by long periods of partial upper airway obstruction (UAO) with low apnea-hypopnea indices (AHI). By measuring snoring and Stertor, Sonomat studies allow quantification of these periods of partial UAO. AIM To determine whether transcutaneous CO2 (TcCO2 ) levels correlate with increasing levels of partial UAO and to examine patterns of ΔTcCo2 in the transitions from (1) wakefulness to sleep and (2) NREM to REM sleep. METHODS This was a retrospective review of sleep studies in 7 asymptomatic controls aged 7-12 years and 62 symptomatic children with suspected SDB and no comorbidities, aged 2-13 years. Both groups underwent overnight polysomnography, including continuous TcCO2 , at one of two paediatric hospitals in Sydney. Changes in carbon dioxide levels between wake to NREM (sleep onset) and NREM to REM sleep were evaluated using an all-night TcCO2 trace time-linked to a hypnogram. Paired Sonomat recordings were used to quantify periods of UAO in the symptomatic group. RESULTS The ΔTcCO2 at sleep onset was greater in SDB children than controls and ΔTcCO2 with sleep onset correlated with the duration of partial obstruction (r=0.60, p

  • snoring and Stertor are associated with more sleep disturbance than apneas and hypopneas in pediatric sdb
    Sleep and Breathing, 2019
    Co-Authors: Mark Norman, Henley Harrison, Karen A Waters, Colin E Sullivan
    Abstract:

    Polysomnography is not recommended for children at home and does not adequately capture partial upper airway obstruction (snoring and Stertor), the dominant pathology in pediatric sleep-disordered breathing. New methods are required for assessment. Aims were to assess sleep disruption linked to partial upper airway obstruction and to evaluate unattended Sonomat use in a large group of children at home. Children with suspected obstructive sleep apnea (OSA) had a single home-based Sonomat recording (n = 231). Quantification of breath sound recordings allowed identification of snoring, Stertor, and apneas/hypopneas. Movement signals were used to measure quiescent (sleep) time and sleep disruption. Successful recordings occurred in 213 (92%) and 113 (53%) had no OSA whereas only 11 (5%) had no partial obstruction. Snore/Stertor occurred more frequently (15.3 [5.4, 30.1] events/h) and for a longer total duration (69.9 min [15.7, 140.9]) than obstructive/mixed apneas and hypopneas (0.8 [0.0, 4.7] events/h, 1.2 min [0.0, 8.5]); both p < 0.0001. Many non-OSA children had more partial obstruction than those with OSA. Most intervals between snore and Stertor runs were < 60 s (79% and 61% respectively), indicating that they occur in clusters. Of 14,145 respiratory-induced movement arousals, 70% were preceded by runs of snore/Stertor with the remainder associated with apneas/hypopneas. Runs of snoring and Stertor occur much more frequently than obstructive apneas/hypopneas and are associated with a greater degree of sleep disruption. Children with and without OSA are frequently indistinguishable regarding the amount, frequency, and the degree of sleep disturbance caused by snoring and Stertor.

  • Snoring and Stertor are associated with more sleep disturbance than apneas and hypopneas in pediatric SDB.
    Sleep and Breathing, 2019
    Co-Authors: Mark Norman, Karen A Waters, Henley C. Harrison, Colin E Sullivan
    Abstract:

    Polysomnography is not recommended for children at home and does not adequately capture partial upper airway obstruction (snoring and Stertor), the dominant pathology in pediatric sleep-disordered breathing. New methods are required for assessment. Aims were to assess sleep disruption linked to partial upper airway obstruction and to evaluate unattended Sonomat use in a large group of children at home. Children with suspected obstructive sleep apnea (OSA) had a single home-based Sonomat recording (n = 231). Quantification of breath sound recordings allowed identification of snoring, Stertor, and apneas/hypopneas. Movement signals were used to measure quiescent (sleep) time and sleep disruption. Successful recordings occurred in 213 (92%) and 113 (53%) had no OSA whereas only 11 (5%) had no partial obstruction. Snore/Stertor occurred more frequently (15.3 [5.4, 30.1] events/h) and for a longer total duration (69.9 min [15.7, 140.9]) than obstructive/mixed apneas and hypopneas (0.8 [0.0, 4.7] events/h, 1.2 min [0.0, 8.5]); both p 

  • Validation of the Sonomat Against PSG and Quantitative Measurement of Partial Upper Airway Obstruction in Children With Sleep-Disordered Breathing.
    Sleep, 2017
    Co-Authors: Mark Norman, Karen A Waters, S. Pithers, Arthur Teng, Colin E Sullivan
    Abstract:

    Study Objectives: To validate the Sonomat against polysomnography (PSG) metrics in children and to objectively measure snoring and Stertor to produce a quantitative indicator of partial upper airway obstruction that accurately reflects the pathology of pediatric sleep-disordered breathing (SDB). Methods: Simultaneous PSG and Sonomat recordings were performed in 76 children (46 male, age 5.8 ± 2.8, BMI = 18.5 ± 3.8 kg/m2). Sleep time, individual respiratory events and the apnea/hypopnea index (AHI) were compared. Obstructed breathing sounds were measured from the unobtrusive non-contact experimental device. Results: There was no significant difference in total sleep time (TST), respiratory events or AHI values, the latter over-estimated by 0.3 events hr-1 by the Sonomat. Poor signal quality was minimal and gender, BMI, and body position did not adversely influence event detection. Obstructive and central events were classified correctly. The number of runs and duration of snoring (13 399 events, 20% TST) and Stertor (5748 events, 24% TST) were an order of magnitude greater than respiratory events (1367 events, 1% TST). Many children defined as normal by PSG had just as many or more runs of snoring and Stertor as those with mild, moderate and severe obstructive sleep apnea (OSA). Conclusions: The Sonomat accurately diagnoses SDB in children using current metrics. In addition, it permits quantification of partial airway obstruction that can be used to better describe pediatric SDB. Its non-contact design makes it ideal for use in children.

Mark B. Norman - One of the best experts on this subject based on the ideXlab platform.

  • Snoring and Stertor are associated with more sleep disturbance than apneas and hypopneas in pediatric SDB
    Sleep and Breathing, 2019
    Co-Authors: Mark B. Norman, Karen A Waters, Henley C. Harrison, Colin E Sullivan
    Abstract:

    Purpose Polysomnography is not recommended for children at home and does not adequately capture partial upper airway obstruction (snoring and Stertor), the dominant pathology in pediatric sleep-disordered breathing. New methods are required for assessment. Aims were to assess sleep disruption linked to partial upper airway obstruction and to evaluate unattended Sonomat use in a large group of children at home. Methods Children with suspected obstructive sleep apnea (OSA) had a single home-based Sonomat recording ( n  = 231). Quantification of breath sound recordings allowed identification of snoring, Stertor, and apneas/hypopneas. Movement signals were used to measure quiescent (sleep) time and sleep disruption. Results Successful recordings occurred in 213 (92%) and 113 (53%) had no OSA whereas only 11 (5%) had no partial obstruction. Snore/Stertor occurred more frequently (15.3 [5.4, 30.1] events/h) and for a longer total duration (69.9 min [15.7, 140.9]) than obstructive/mixed apneas and hypopneas (0.8 [0.0, 4.7] events/h, 1.2 min [0.0, 8.5]); both p  

Henley C. Harrison - One of the best experts on this subject based on the ideXlab platform.

  • Snoring and Stertor are associated with more sleep disturbance than apneas and hypopneas in pediatric SDB
    Sleep and Breathing, 2019
    Co-Authors: Mark B. Norman, Karen A Waters, Henley C. Harrison, Colin E Sullivan
    Abstract:

    Purpose Polysomnography is not recommended for children at home and does not adequately capture partial upper airway obstruction (snoring and Stertor), the dominant pathology in pediatric sleep-disordered breathing. New methods are required for assessment. Aims were to assess sleep disruption linked to partial upper airway obstruction and to evaluate unattended Sonomat use in a large group of children at home. Methods Children with suspected obstructive sleep apnea (OSA) had a single home-based Sonomat recording ( n  = 231). Quantification of breath sound recordings allowed identification of snoring, Stertor, and apneas/hypopneas. Movement signals were used to measure quiescent (sleep) time and sleep disruption. Results Successful recordings occurred in 213 (92%) and 113 (53%) had no OSA whereas only 11 (5%) had no partial obstruction. Snore/Stertor occurred more frequently (15.3 [5.4, 30.1] events/h) and for a longer total duration (69.9 min [15.7, 140.9]) than obstructive/mixed apneas and hypopneas (0.8 [0.0, 4.7] events/h, 1.2 min [0.0, 8.5]); both p  

  • Snoring and Stertor are associated with more sleep disturbance than apneas and hypopneas in pediatric SDB.
    Sleep and Breathing, 2019
    Co-Authors: Mark Norman, Karen A Waters, Henley C. Harrison, Colin E Sullivan
    Abstract:

    Polysomnography is not recommended for children at home and does not adequately capture partial upper airway obstruction (snoring and Stertor), the dominant pathology in pediatric sleep-disordered breathing. New methods are required for assessment. Aims were to assess sleep disruption linked to partial upper airway obstruction and to evaluate unattended Sonomat use in a large group of children at home. Children with suspected obstructive sleep apnea (OSA) had a single home-based Sonomat recording (n = 231). Quantification of breath sound recordings allowed identification of snoring, Stertor, and apneas/hypopneas. Movement signals were used to measure quiescent (sleep) time and sleep disruption. Successful recordings occurred in 213 (92%) and 113 (53%) had no OSA whereas only 11 (5%) had no partial obstruction. Snore/Stertor occurred more frequently (15.3 [5.4, 30.1] events/h) and for a longer total duration (69.9 min [15.7, 140.9]) than obstructive/mixed apneas and hypopneas (0.8 [0.0, 4.7] events/h, 1.2 min [0.0, 8.5]); both p