Stomach Cancer

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Alicja Wolk - One of the best experts on this subject based on the ideXlab platform.

  • processed meat consumption dietary nitrosamines and Stomach Cancer risk in a cohort of swedish women
    International Journal of Cancer, 2006
    Co-Authors: Susanna C Larsson, Leif Bergkvist, Alicja Wolk
    Abstract:

    Processed meat consumption has been associated with an increased risk of Stomach Cancer in some epidemiological studies (mainly case–control). Nitrosamines may be responsible for this association, but few studies have directly examined nitrosamine intake in relation to Stomach Cancer risk. We prospectively investigated the associations between intakes of processed meat, other meats and N-nitrosodimethylamine (the most frequently occurring nitrosamine in foods) with risk of Stomach Cancer among 61,433 women who were enrolled in the population-based Swedish Mammography Cohort. Information on diet was collected at baseline (between 1987 and 1990) and updated in 1997. During 18 years of follow-up, 156 incident cases of Stomach Cancer were ascertained. High consumption of processed meat, but not of other meats (i.e., red meat, fish and poultry), was associated with a statistically significant increased risk of Stomach Cancer. After adjustment for potential confounders, the hazard ratios for the highest compared with the lowest category of intake were 1.66 (95% CI = 1.13–2.45) for all processed meats, 1.55 (95% CI = 1.00–2.41) for bacon or side pork, 1.50 (95% CI = 0.93–2.41) for sausage or hotdogs and 1.48 (95% CI= 0.99–2.22) for ham or salami. Stomach Cancer risk was 2-fold higher among women in the top quintile of N-nitrosodimethylamine intake when compared with those in the bottom quintile (hazard ratio = 1.96; 95% CI = 1.08–3.58). Our findings suggest that high consumption of processed meat may increase the risk of Stomach Cancer. Dietary nitrosamines might be responsible for the positive association. © 2006 Wiley-Liss, Inc.

  • Processed meat consumption and Stomach Cancer risk : A meta-analysis
    Journal of the National Cancer Institute, 2006
    Co-Authors: Susanna C Larsson, Nicola Orsini, Alicja Wolk
    Abstract:

    Background: The relationship between processed meat consumption and the risk of Stomach Cancer is controversial. We conducted a meta-analysis to summarize available evidence from cohort and case – control studies on this issue. Methods: We searched Medline for studies of processed meat consumption and Stomach Cancer published from January 1966 through March 2006. Random-effects models were used to pool the relative risks from individual studies. All statistical tests were two-sided. Results: Six prospective cohort studies (involving 2209 Stomach Cancer patients) and nine case – control studies (2495 case patients) were eligible for inclusion in the dose–response meta-analysis of processed meat consumption. The estimated summary relative risks of Stomach Cancer for an increase in processed meat consumption of 30 g/day, approximately half of an average serving, were 1.15 (95% confi dence interval [CI] = 1.04 to 1.27) for the cohort studies and 1.38 (95% CI = 1.19 to 1.60) for the case – control studies. There was no statistically signifi cant heterogeneity among the cohort studies ( P = .42) or among the case – control studies ( P = .19). In three cohort and four case – control studies that examined the association between bacon consumption and Stomach Cancer, the summary relative risk was 1.37 (95% CI = 1.17 to 1.61) for the highest versus lowest intake categories of bacon, without heterogeneity among these studies ( P = .66). Conclusion: Increased consumption of processed meat is associated with an increased risk of Stomach Cancer. However, the possibility that the association may be confounded or modifi ed by other factors cannot be ruled out. [J Natl Cancer Inst 2006;98: 1078 – 87 ]

Geunam Song - One of the best experts on this subject based on the ideXlab platform.

  • uncovered self expandable metal stents sems for gastric outlet obstruction caused by Stomach Cancer
    Clinical Endoscopy, 2008
    Co-Authors: Hyoungyeol Park, Dae Hwan Kang, Taiin Ha, Chan Ho Park, Cheolwoong Choi, Geunam Song
    Abstract:

    Background/Aims: The use of self-expandable metal stents (SEMS) is a safe and efficacious method for palliating malignant gastric outlet obstruction. However, few reports have assessed clinical outcome after the insertion of SEMS for malignant gastric outlet obstruction caused by Stomach Cancer. The aim of this study was to assess the usefulness of uncovered SEMS in patients with malignant gastric outlet obstruction caused by Stomach Cancer. Methods: We evaluated 62 patients with gastric outlet obstruction caused by Stomach Cancer treated by the implantation of uncovered SEMS. A total of 62 patients (43 males, 19 females) were treated between August 2000 and March 2007. A scoring system was used to grade the ability to eat. Results: Stent implantation was successful in 61 (98.4%) patients. Relief of obstructive symptoms was achieved in 49 (80.3%) patients. The mean survival duration was 143 days. The mean stent patency time was 103.5 days. An improvement in the ability to eat using the scoring system was statistically significant (p<0.05). Conclusions: Endoscopic placement of uncovered SEMS is a safe and effective treatment for the palliation of patients with inoperable malignant gastric outlet obstruction caused by Stomach Cancer. (Korean J Gastrointest Endosc 2008;36:57-63)

  • self expandable metallic stents for palliation of patients with malignant gastric outlet obstruction caused by Stomach Cancer
    World Journal of Gastroenterology, 2007
    Co-Authors: Dae Hwan Kang, Geunam Song
    Abstract:

    CONCLUSION: Endoscopic placement of self-expandable metallic stents is a safe and effective treatment for the palliation of patients with inoperable malignant gastric outlet obstruction caused by Stomach Cancer.

Susanna C Larsson - One of the best experts on this subject based on the ideXlab platform.

  • processed meat consumption dietary nitrosamines and Stomach Cancer risk in a cohort of swedish women
    International Journal of Cancer, 2006
    Co-Authors: Susanna C Larsson, Leif Bergkvist, Alicja Wolk
    Abstract:

    Processed meat consumption has been associated with an increased risk of Stomach Cancer in some epidemiological studies (mainly case–control). Nitrosamines may be responsible for this association, but few studies have directly examined nitrosamine intake in relation to Stomach Cancer risk. We prospectively investigated the associations between intakes of processed meat, other meats and N-nitrosodimethylamine (the most frequently occurring nitrosamine in foods) with risk of Stomach Cancer among 61,433 women who were enrolled in the population-based Swedish Mammography Cohort. Information on diet was collected at baseline (between 1987 and 1990) and updated in 1997. During 18 years of follow-up, 156 incident cases of Stomach Cancer were ascertained. High consumption of processed meat, but not of other meats (i.e., red meat, fish and poultry), was associated with a statistically significant increased risk of Stomach Cancer. After adjustment for potential confounders, the hazard ratios for the highest compared with the lowest category of intake were 1.66 (95% CI = 1.13–2.45) for all processed meats, 1.55 (95% CI = 1.00–2.41) for bacon or side pork, 1.50 (95% CI = 0.93–2.41) for sausage or hotdogs and 1.48 (95% CI= 0.99–2.22) for ham or salami. Stomach Cancer risk was 2-fold higher among women in the top quintile of N-nitrosodimethylamine intake when compared with those in the bottom quintile (hazard ratio = 1.96; 95% CI = 1.08–3.58). Our findings suggest that high consumption of processed meat may increase the risk of Stomach Cancer. Dietary nitrosamines might be responsible for the positive association. © 2006 Wiley-Liss, Inc.

  • Processed meat consumption and Stomach Cancer risk : A meta-analysis
    Journal of the National Cancer Institute, 2006
    Co-Authors: Susanna C Larsson, Nicola Orsini, Alicja Wolk
    Abstract:

    Background: The relationship between processed meat consumption and the risk of Stomach Cancer is controversial. We conducted a meta-analysis to summarize available evidence from cohort and case – control studies on this issue. Methods: We searched Medline for studies of processed meat consumption and Stomach Cancer published from January 1966 through March 2006. Random-effects models were used to pool the relative risks from individual studies. All statistical tests were two-sided. Results: Six prospective cohort studies (involving 2209 Stomach Cancer patients) and nine case – control studies (2495 case patients) were eligible for inclusion in the dose–response meta-analysis of processed meat consumption. The estimated summary relative risks of Stomach Cancer for an increase in processed meat consumption of 30 g/day, approximately half of an average serving, were 1.15 (95% confi dence interval [CI] = 1.04 to 1.27) for the cohort studies and 1.38 (95% CI = 1.19 to 1.60) for the case – control studies. There was no statistically signifi cant heterogeneity among the cohort studies ( P = .42) or among the case – control studies ( P = .19). In three cohort and four case – control studies that examined the association between bacon consumption and Stomach Cancer, the summary relative risk was 1.37 (95% CI = 1.17 to 1.61) for the highest versus lowest intake categories of bacon, without heterogeneity among these studies ( P = .66). Conclusion: Increased consumption of processed meat is associated with an increased risk of Stomach Cancer. However, the possibility that the association may be confounded or modifi ed by other factors cannot be ruled out. [J Natl Cancer Inst 2006;98: 1078 – 87 ]

Zheng Sun - One of the best experts on this subject based on the ideXlab platform.

  • index based dietary patterns and Stomach Cancer in a chinese population
    European Journal of Cancer Prevention, 2021
    Co-Authors: Yuhui Zhu, Somee Jeong, Jinyi Zhou, Ziyi Jin, Renqiang Han, Jie Yang, Xiaofeng Zhang, Xushan Wang, Aiming Liu, Zheng Sun
    Abstract:

    OBJECTIVES Dietary factors are of importance in the development of Stomach Cancer. This study aims to examine index-based dietary patterns associated with Stomach Cancer in a Chinese population. METHODS Using data from a population-based case-control study conducted in Jiangsu Province, China, we included a total of 8432 participants (1900 Stomach Cancer cases and 6532 controls). Dietary data collected by food frequency questionnaire was evaluated by modified Chinese Healthy Eating Index-2016 (mCHEI-2016) and the US Healthy Eating Index-2015 (HEI-2015). Multiple logistic regression analyses were applied to examine the association of mCHEI-2016 and HEI-2015 with Stomach Cancer while adjusting for potential confounders. The possible interactions between mCHEI-2016 or HEI-2015 and established risk factors were explored. RESULTS Among nonproxy interviews, after adjusting for potential confounding factors, a higher score of sodium, reflecting lower intake per day, was inversely associated with Stomach Cancer [odds ratio (OR), 0.95; 95% CI, 0.91-0.99 for mCHEI-2016; OR, 0.97; 95% CI, 0.94-0.99 for HEI-2015]. No clear associations with Stomach Cancer were identified for total scores of HEI-2015 (OR, 0.98; 95% CI, 0.87-1.10 with a 10-point increase, P trend = 0.98) and mCHEI-2016 (OR, 1.05; 95% CI, 0.94-1.17 with a 10-point increase, P trend = 0.22). However, the relation between Stomach Cancer and the mCHEI-2016 was modified by BMI, with a possible inverse association in normal-weight subjects. CONCLUSIONS Our findings highlight that reduced intake of dietary sodium would prevent the development of Stomach Cancer. The data indicate a heterogeneity between normal weight and overweight's dietary factors in relation to Stomach Cancer.

  • dietary intake of fatty acids total cholesterol and Stomach Cancer in a chinese population
    Nutrients, 2019
    Co-Authors: Yuhui Zhu, Somee Jeong, Jinyi Zhou, Ziyi Jin, Renqiang Han, Jie Yang, Xiaofeng Zhang, Xushan Wang, Aiming Liu, Zheng Sun
    Abstract:

    To investigate the associations between dietary fatty acids and cholesterol consumption and Stomach Cancer (SC), we analyzed data from a population-based case-control study with a total of 1900 SC cases and 6532 controls. Dietary data and other risk or protective factors were collected by face-to-face interviews in Jiangsu Province, China, from 2003 to 2010. Adjusted odds ratios (ORs) and 95% confidence intervals (CIs) were estimated using multiple unconditional logistic regression models and an energy-adjusted method. The joint associations between dietary factors and known risk factors on SC were examined. We observed positive associations between dietary saturated fatty acids (SFAs), monounsaturated fatty acids (MUFAs), and total cholesterol and the development of SC, comparing the highest versus lowest quarters. Increased intakes of dietary SFAs (p-trend = 0.005; aOR, 1.11; 95% CI, 1.01–1.22 with a 7 g/day increase as a continuous variable) and total cholesterol (p-trend < 0.001; aOR, 1.13; 95% CI, 1.06–1.22 with a 250 mg/day increase as a continuous variable) were monotonically associated with elevated odds of developing SC. Our results indicate that dietary SFAs, MUFAs, and total cholesterol are associated with Stomach Cancer, which might provide a potential dietary intervention for Stomach Cancer prevention.

Dae Hwan Kang - One of the best experts on this subject based on the ideXlab platform.

  • uncovered self expandable metal stents sems for gastric outlet obstruction caused by Stomach Cancer
    Clinical Endoscopy, 2008
    Co-Authors: Hyoungyeol Park, Dae Hwan Kang, Taiin Ha, Chan Ho Park, Cheolwoong Choi, Geunam Song
    Abstract:

    Background/Aims: The use of self-expandable metal stents (SEMS) is a safe and efficacious method for palliating malignant gastric outlet obstruction. However, few reports have assessed clinical outcome after the insertion of SEMS for malignant gastric outlet obstruction caused by Stomach Cancer. The aim of this study was to assess the usefulness of uncovered SEMS in patients with malignant gastric outlet obstruction caused by Stomach Cancer. Methods: We evaluated 62 patients with gastric outlet obstruction caused by Stomach Cancer treated by the implantation of uncovered SEMS. A total of 62 patients (43 males, 19 females) were treated between August 2000 and March 2007. A scoring system was used to grade the ability to eat. Results: Stent implantation was successful in 61 (98.4%) patients. Relief of obstructive symptoms was achieved in 49 (80.3%) patients. The mean survival duration was 143 days. The mean stent patency time was 103.5 days. An improvement in the ability to eat using the scoring system was statistically significant (p<0.05). Conclusions: Endoscopic placement of uncovered SEMS is a safe and effective treatment for the palliation of patients with inoperable malignant gastric outlet obstruction caused by Stomach Cancer. (Korean J Gastrointest Endosc 2008;36:57-63)

  • self expandable metallic stents for palliation of patients with malignant gastric outlet obstruction caused by Stomach Cancer
    World Journal of Gastroenterology, 2007
    Co-Authors: Dae Hwan Kang, Geunam Song
    Abstract:

    CONCLUSION: Endoscopic placement of self-expandable metallic stents is a safe and effective treatment for the palliation of patients with inoperable malignant gastric outlet obstruction caused by Stomach Cancer.