The Experts below are selected from a list of 168 Experts worldwide ranked by ideXlab platform
Haichen Sun - One of the best experts on this subject based on the ideXlab platform.
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therapeutic effect of gastrotomy on lung infection and dystrophy in patients with traumatic vagus nerve injury
Chinese Journal of Trauma, 2015Co-Authors: Chao Lin, Qiyong Mei, Kaiwei Han, Hai Jin, Shun Gong, Ning Liu, Haichen SunAbstract:Objective To examine the occurrence of traumatic lower cranial nerve injury and the therapeutic effect of gastrostomy on vagus nerve injury. Methods Clinical data of 45 patients sustaining traumatic lower cranial nerve injury were retrospectively analyzed. There were 32 males and 13 females, with the age of (34.5±8.8)years. Injury resulted from high falls in 22 patients, traffic accidents in 15 patients and other in 8 patients. Non-operative treatments, nutrition and hormone intervention, improving minicirculation, promoting blood circulation and removing stasis for instance, were performed for the patients with the injury involving the glossopharyngeal nerve (n=12), accessory nerve (n=21) and hypoglossal nerve (n=20). Vagus nerve injury was seen in 32 patients. Fifteen out of the 32 patients underwent gastrotomy and early enteral nutrition support and 17 transnasal gastric catheter indwelling and enteral nutrition support. Lung infection and dystrophy were evaluated after operation. Results Two patients had lung infection and one dystrophy after gastrotomy. In contrast, 9 patients had lung infection and one dystrophy after transnasal Stomach Intubation surgery (P<0.05). At follow-up, the complications were cured in gastrotomy group, but only 7 lung infection and 5 dystrophy were cured in indwelling catheter group. Conclusions Vagus nerve injury is most common in lower cranial nerve injury and manifested with choking on water and dysphagia. Gastrostomy in combination with early enteral nutrition therapy is effective to improve the nutritional status and reduce lung infection in patients with traumatic vagus nerve injury. Key words: Cranial nerve injuries; Traumatic brain injuries; Vagus nerve; Gastrostomy
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Therapeutic effect of gastrotomy on lung infection and dystrophy in patients with traumatic vagus nerve injury
Chinese Journal of Trauma, 2015Co-Authors: Chao Lin, Qiyong Mei, Kaiwei Han, Shun Gong, Ning Liu, Jin Hai, Gu Jinmao, Haichen SunAbstract:Objective To examine the occurrence of traumatic lower cranial nerve injury and the therapeutic effect of gastrostomy on vagus nerve injury. Methods Clinical data of 45 patients sustaining traumatic lower cranial nerve injury were retrospectively analyzed. There were 32 males and 13 females, with the age of (34.5±8.8)years. Injury resulted from high falls in 22 patients, traffic accidents in 15 patients and other in 8 patients. Non-operative treatments, nutrition and hormone intervention, improving minicirculation, promoting blood circulation and removing stasis for instance, were performed for the patients with the injury involving the glossopharyngeal nerve (n=12), accessory nerve (n=21) and hypoglossal nerve (n=20). Vagus nerve injury was seen in 32 patients. Fifteen out of the 32 patients underwent gastrotomy and early enteral nutrition support and 17 transnasal gastric catheter indwelling and enteral nutrition support. Lung infection and dystrophy were evaluated after operation. Results Two patients had lung infection and one dystrophy after gastrotomy. In contrast, 9 patients had lung infection and one dystrophy after transnasal Stomach Intubation surgery (P
Emily J. Jenkins - One of the best experts on this subject based on the ideXlab platform.
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Pathology, clinical signs, and tissue distribution of Toxoplasma gondii in experimentally infected reindeer (Rangifer tarandus).
International journal for parasitology. Parasites and wildlife, 2017Co-Authors: Émilie Bouchard, Rajnish Sharma, Nicholas Bachand, Alvin A. Gajadhar, Emily J. JenkinsAbstract:Abstract Toxoplasma gondii is a zoonotic parasite found in vertebrates worldwide for which felids serve as definitive hosts. Despite low densities of felids in northern Canada, Inuit people in some regions show unexpectedly high levels of exposure, possibly through handling and consumption of Arctic wildlife. Free-ranging caribou ( Rangifer tarandus ) are widely harvested for food across the Canadian North, show evidence of seroexposure to T. gondii , and are currently declining in numbers throughout the Arctic. We experimentally infected three captive reindeer (conspecific with caribou) with 1000, 5000 or 10,000 oocysts of T. gondii via Stomach Intubation to assess clinical signs of infection, pathology, and tissue distribution. An unexposed reindeer served as a negative control. Signs of stress, aggression, and depression were noted for the first two weeks following infection. By 4 weeks post infection, all infected reindeer were positive on a modified agglutination test at the highest titer tested (1:200) for antibodies to T. gondii . At 20 weeks post infection, no gross abnormalities were observed on necropsy. Following histopathology and immunohistochemistry, tissue cysts were visualized in the reindeer given the highest and lowest dose of oocysts. Focal pleuritis and alveolitis were associated with respiratory problems in reindeer given the middle dose. DNA of T. gondii was detected following traditional DNA extraction and conventional PCR on 25 mg samples from 17/33 muscles and organs, and by magnetic capture DNA extraction from 100 g samples from all 26 tissues examined. This research demonstrated that reindeer/caribou can serve as intermediate hosts for T. gondii , and that the parasite may be associated with health effects in wildlife. The presence of T. gondii in all tissues tested, many of which are commonly consumed raw, smoked, or dried in northern communities, suggests that caribou may serve as a source of human exposure to T. gondii .
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Pathology, clinical signs, and tissue distribution of Toxoplasma gondii in experimentally infected reindeer (Rangifer tarandus)
Elsevier, 2017Co-Authors: Émilie Bouchard, Rajnish Sharma, Nicholas Bachand, Alvin A. Gajadhar, Emily J. JenkinsAbstract:Toxoplasma gondii is a zoonotic parasite found in vertebrates worldwide for which felids serve as definitive hosts. Despite low densities of felids in northern Canada, Inuit people in some regions show unexpectedly high levels of exposure, possibly through handling and consumption of Arctic wildlife. Free-ranging caribou (Rangifer tarandus) are widely harvested for food across the Canadian North, show evidence of seroexposure to T. gondii, and are currently declining in numbers throughout the Arctic. We experimentally infected three captive reindeer (conspecific with caribou) with 1000, 5000 or 10,000 oocysts of T. gondii via Stomach Intubation to assess clinical signs of infection, pathology, and tissue distribution. An unexposed reindeer served as a negative control. Signs of stress, aggression, and depression were noted for the first two weeks following infection. By 4 weeks post infection, all infected reindeer were positive on a modified agglutination test at the highest titer tested (1:200) for antibodies to T. gondii. At 20 weeks post infection, no gross abnormalities were observed on necropsy. Following histopathology and immunohistochemistry, tissue cysts were visualized in the reindeer given the highest and lowest dose of oocysts. Focal pleuritis and alveolitis were associated with respiratory problems in reindeer given the middle dose. DNA of T. gondii was detected following traditional DNA extraction and conventional PCR on 25 mg samples from 17/33 muscles and organs, and by magnetic capture DNA extraction from 100 g samples from all 26 tissues examined. This research demonstrated that reindeer/caribou can serve as intermediate hosts for T. gondii, and that the parasite may be associated with health effects in wildlife. The presence of T. gondii in all tissues tested, many of which are commonly consumed raw, smoked, or dried in northern communities, suggests that caribou may serve as a source of human exposure to T. gondii. Keywords: Experimental infection, Magnetic capture, Reindeer, Toxoplasm
Chao Lin - One of the best experts on this subject based on the ideXlab platform.
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therapeutic effect of gastrotomy on lung infection and dystrophy in patients with traumatic vagus nerve injury
Chinese Journal of Trauma, 2015Co-Authors: Chao Lin, Qiyong Mei, Kaiwei Han, Hai Jin, Shun Gong, Ning Liu, Haichen SunAbstract:Objective To examine the occurrence of traumatic lower cranial nerve injury and the therapeutic effect of gastrostomy on vagus nerve injury. Methods Clinical data of 45 patients sustaining traumatic lower cranial nerve injury were retrospectively analyzed. There were 32 males and 13 females, with the age of (34.5±8.8)years. Injury resulted from high falls in 22 patients, traffic accidents in 15 patients and other in 8 patients. Non-operative treatments, nutrition and hormone intervention, improving minicirculation, promoting blood circulation and removing stasis for instance, were performed for the patients with the injury involving the glossopharyngeal nerve (n=12), accessory nerve (n=21) and hypoglossal nerve (n=20). Vagus nerve injury was seen in 32 patients. Fifteen out of the 32 patients underwent gastrotomy and early enteral nutrition support and 17 transnasal gastric catheter indwelling and enteral nutrition support. Lung infection and dystrophy were evaluated after operation. Results Two patients had lung infection and one dystrophy after gastrotomy. In contrast, 9 patients had lung infection and one dystrophy after transnasal Stomach Intubation surgery (P<0.05). At follow-up, the complications were cured in gastrotomy group, but only 7 lung infection and 5 dystrophy were cured in indwelling catheter group. Conclusions Vagus nerve injury is most common in lower cranial nerve injury and manifested with choking on water and dysphagia. Gastrostomy in combination with early enteral nutrition therapy is effective to improve the nutritional status and reduce lung infection in patients with traumatic vagus nerve injury. Key words: Cranial nerve injuries; Traumatic brain injuries; Vagus nerve; Gastrostomy
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Therapeutic effect of gastrotomy on lung infection and dystrophy in patients with traumatic vagus nerve injury
Chinese Journal of Trauma, 2015Co-Authors: Chao Lin, Qiyong Mei, Kaiwei Han, Shun Gong, Ning Liu, Jin Hai, Gu Jinmao, Haichen SunAbstract:Objective To examine the occurrence of traumatic lower cranial nerve injury and the therapeutic effect of gastrostomy on vagus nerve injury. Methods Clinical data of 45 patients sustaining traumatic lower cranial nerve injury were retrospectively analyzed. There were 32 males and 13 females, with the age of (34.5±8.8)years. Injury resulted from high falls in 22 patients, traffic accidents in 15 patients and other in 8 patients. Non-operative treatments, nutrition and hormone intervention, improving minicirculation, promoting blood circulation and removing stasis for instance, were performed for the patients with the injury involving the glossopharyngeal nerve (n=12), accessory nerve (n=21) and hypoglossal nerve (n=20). Vagus nerve injury was seen in 32 patients. Fifteen out of the 32 patients underwent gastrotomy and early enteral nutrition support and 17 transnasal gastric catheter indwelling and enteral nutrition support. Lung infection and dystrophy were evaluated after operation. Results Two patients had lung infection and one dystrophy after gastrotomy. In contrast, 9 patients had lung infection and one dystrophy after transnasal Stomach Intubation surgery (P
Émilie Bouchard - One of the best experts on this subject based on the ideXlab platform.
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Pathology, clinical signs, and tissue distribution of Toxoplasma gondii in experimentally infected reindeer (Rangifer tarandus).
International journal for parasitology. Parasites and wildlife, 2017Co-Authors: Émilie Bouchard, Rajnish Sharma, Nicholas Bachand, Alvin A. Gajadhar, Emily J. JenkinsAbstract:Abstract Toxoplasma gondii is a zoonotic parasite found in vertebrates worldwide for which felids serve as definitive hosts. Despite low densities of felids in northern Canada, Inuit people in some regions show unexpectedly high levels of exposure, possibly through handling and consumption of Arctic wildlife. Free-ranging caribou ( Rangifer tarandus ) are widely harvested for food across the Canadian North, show evidence of seroexposure to T. gondii , and are currently declining in numbers throughout the Arctic. We experimentally infected three captive reindeer (conspecific with caribou) with 1000, 5000 or 10,000 oocysts of T. gondii via Stomach Intubation to assess clinical signs of infection, pathology, and tissue distribution. An unexposed reindeer served as a negative control. Signs of stress, aggression, and depression were noted for the first two weeks following infection. By 4 weeks post infection, all infected reindeer were positive on a modified agglutination test at the highest titer tested (1:200) for antibodies to T. gondii . At 20 weeks post infection, no gross abnormalities were observed on necropsy. Following histopathology and immunohistochemistry, tissue cysts were visualized in the reindeer given the highest and lowest dose of oocysts. Focal pleuritis and alveolitis were associated with respiratory problems in reindeer given the middle dose. DNA of T. gondii was detected following traditional DNA extraction and conventional PCR on 25 mg samples from 17/33 muscles and organs, and by magnetic capture DNA extraction from 100 g samples from all 26 tissues examined. This research demonstrated that reindeer/caribou can serve as intermediate hosts for T. gondii , and that the parasite may be associated with health effects in wildlife. The presence of T. gondii in all tissues tested, many of which are commonly consumed raw, smoked, or dried in northern communities, suggests that caribou may serve as a source of human exposure to T. gondii .
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Pathology, clinical signs, and tissue distribution of Toxoplasma gondii in experimentally infected reindeer (Rangifer tarandus)
Elsevier, 2017Co-Authors: Émilie Bouchard, Rajnish Sharma, Nicholas Bachand, Alvin A. Gajadhar, Emily J. JenkinsAbstract:Toxoplasma gondii is a zoonotic parasite found in vertebrates worldwide for which felids serve as definitive hosts. Despite low densities of felids in northern Canada, Inuit people in some regions show unexpectedly high levels of exposure, possibly through handling and consumption of Arctic wildlife. Free-ranging caribou (Rangifer tarandus) are widely harvested for food across the Canadian North, show evidence of seroexposure to T. gondii, and are currently declining in numbers throughout the Arctic. We experimentally infected three captive reindeer (conspecific with caribou) with 1000, 5000 or 10,000 oocysts of T. gondii via Stomach Intubation to assess clinical signs of infection, pathology, and tissue distribution. An unexposed reindeer served as a negative control. Signs of stress, aggression, and depression were noted for the first two weeks following infection. By 4 weeks post infection, all infected reindeer were positive on a modified agglutination test at the highest titer tested (1:200) for antibodies to T. gondii. At 20 weeks post infection, no gross abnormalities were observed on necropsy. Following histopathology and immunohistochemistry, tissue cysts were visualized in the reindeer given the highest and lowest dose of oocysts. Focal pleuritis and alveolitis were associated with respiratory problems in reindeer given the middle dose. DNA of T. gondii was detected following traditional DNA extraction and conventional PCR on 25 mg samples from 17/33 muscles and organs, and by magnetic capture DNA extraction from 100 g samples from all 26 tissues examined. This research demonstrated that reindeer/caribou can serve as intermediate hosts for T. gondii, and that the parasite may be associated with health effects in wildlife. The presence of T. gondii in all tissues tested, many of which are commonly consumed raw, smoked, or dried in northern communities, suggests that caribou may serve as a source of human exposure to T. gondii. Keywords: Experimental infection, Magnetic capture, Reindeer, Toxoplasm
Qiyong Mei - One of the best experts on this subject based on the ideXlab platform.
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therapeutic effect of gastrotomy on lung infection and dystrophy in patients with traumatic vagus nerve injury
Chinese Journal of Trauma, 2015Co-Authors: Chao Lin, Qiyong Mei, Kaiwei Han, Hai Jin, Shun Gong, Ning Liu, Haichen SunAbstract:Objective To examine the occurrence of traumatic lower cranial nerve injury and the therapeutic effect of gastrostomy on vagus nerve injury. Methods Clinical data of 45 patients sustaining traumatic lower cranial nerve injury were retrospectively analyzed. There were 32 males and 13 females, with the age of (34.5±8.8)years. Injury resulted from high falls in 22 patients, traffic accidents in 15 patients and other in 8 patients. Non-operative treatments, nutrition and hormone intervention, improving minicirculation, promoting blood circulation and removing stasis for instance, were performed for the patients with the injury involving the glossopharyngeal nerve (n=12), accessory nerve (n=21) and hypoglossal nerve (n=20). Vagus nerve injury was seen in 32 patients. Fifteen out of the 32 patients underwent gastrotomy and early enteral nutrition support and 17 transnasal gastric catheter indwelling and enteral nutrition support. Lung infection and dystrophy were evaluated after operation. Results Two patients had lung infection and one dystrophy after gastrotomy. In contrast, 9 patients had lung infection and one dystrophy after transnasal Stomach Intubation surgery (P<0.05). At follow-up, the complications were cured in gastrotomy group, but only 7 lung infection and 5 dystrophy were cured in indwelling catheter group. Conclusions Vagus nerve injury is most common in lower cranial nerve injury and manifested with choking on water and dysphagia. Gastrostomy in combination with early enteral nutrition therapy is effective to improve the nutritional status and reduce lung infection in patients with traumatic vagus nerve injury. Key words: Cranial nerve injuries; Traumatic brain injuries; Vagus nerve; Gastrostomy
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Therapeutic effect of gastrotomy on lung infection and dystrophy in patients with traumatic vagus nerve injury
Chinese Journal of Trauma, 2015Co-Authors: Chao Lin, Qiyong Mei, Kaiwei Han, Shun Gong, Ning Liu, Jin Hai, Gu Jinmao, Haichen SunAbstract:Objective To examine the occurrence of traumatic lower cranial nerve injury and the therapeutic effect of gastrostomy on vagus nerve injury. Methods Clinical data of 45 patients sustaining traumatic lower cranial nerve injury were retrospectively analyzed. There were 32 males and 13 females, with the age of (34.5±8.8)years. Injury resulted from high falls in 22 patients, traffic accidents in 15 patients and other in 8 patients. Non-operative treatments, nutrition and hormone intervention, improving minicirculation, promoting blood circulation and removing stasis for instance, were performed for the patients with the injury involving the glossopharyngeal nerve (n=12), accessory nerve (n=21) and hypoglossal nerve (n=20). Vagus nerve injury was seen in 32 patients. Fifteen out of the 32 patients underwent gastrotomy and early enteral nutrition support and 17 transnasal gastric catheter indwelling and enteral nutrition support. Lung infection and dystrophy were evaluated after operation. Results Two patients had lung infection and one dystrophy after gastrotomy. In contrast, 9 patients had lung infection and one dystrophy after transnasal Stomach Intubation surgery (P