The Experts below are selected from a list of 45 Experts worldwide ranked by ideXlab platform
Kee-hyun Chang - One of the best experts on this subject based on the ideXlab platform.
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evaluation of the lenticuloStriate Arteries with rotational angiography and 3d reconstruction
2005Co-Authors: Hyun-seung Kang, Moon Hee Han, Bae Ju Kwon, O-ki Kwon, Sung Hyun Kim, Kee-hyun ChangAbstract:BACKGROUND AND PURPOSE: Anatomic evaluation of the lenticuloStriate Arteries (LSAs) is important, especially in cases of surgical or endovascular treatment, but biplanar angiography provides limited information. We analyzed the LSAs with rotational angiography (RA) and 3D reconstruction and compared the findings with those of previous autopsy studies. METHODS: We retrospectively reviewed the LSAs on 3D reconstructed RA images (200 sides in 159 cases) to analyze their origin, course, and supplying territories. The angiographic configurations of the LSAs were classified by using the scheme devised by Yasargil. RESULTS: LSAs from the anterior cerebral artery were demonstrated on 140 sides (70%). They originated from the A1 segment in 59 sides, from the A1-A2 junction on 41 sides, and from the A2 segment on 35 sides. They arose as a single trunk and ended as the most medial and anterior perforators in most cases. Arteries from the middle cerebral artery (MCA) were demonstrated on 190 sides (95%). They originated from the M1 segment on 131 sides, from the MCA bifurcation on 26 sides, and from the M2 segment on 33 sides; notably, all LSAs arising from the M2 segment originated from the superior division. In terms of configuration, we identified four major and 11 minor types. The most frequent LSA type was the combination of medial and lateral distal Striate Arteries, which comprised 53 sides (28%). CONCLUSION: Analysis of LSAs with RA and 3D reconstructed images may provide useful information in patients with cerebrovascular diseases, especially before surgical and endovascular treatment.
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Evaluation of the lenticuloStriate Arteries with rotational angiography and 3D reconstruction
2005Co-Authors: Hyun-seung Kang, Moon Hee Han, Bae Ju Kwon, O-ki Kwon, Sung Hyun Kim, Kee-hyun ChangAbstract:is important, especially in cases of surgical or endovascular treatment, but biplanar angiogra-phy provides limited information. We analyzed the LSAs with rotational angiography (RA) and 3D reconstruction and compared the findings with those of previous autopsy studies. METHODS:We retrospectively reviewed the LSAs on 3D reconstructed RA images (200 sides in 159 cases) to analyze their origin, course, and supplying territories. The angiographic configurations of the LSAs were classified by using the scheme devised by Yasargil. RESULTS: LSAs from the anterior cerebral artery were demonstrated on 140 sides (70%). They originated from the A1 segment in 59 sides, from the A1-A2 junction on 41 sides, and from the A2 segment on 35 sides. They arose as a single trunk and ended as the most medial and anterior perforators in most cases. Arteries from the middle cerebral artery (MCA) were demonstrated on 190 sides (95%). They originated from the M1 segment on 131 sides, from the MCA bifurcation on 26 sides, and from the M2 segment on 33 sides; notably, all LSAs arising from the M2 segment originated from the superior division. In terms of configuration, we identified four major and 11 minor types. The most frequent LSA type was the combination of medial and lateral distal Striate Arteries, which comprised 53 sides (28%)
C J Gouveia - One of the best experts on this subject based on the ideXlab platform.
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supravital morphology of small branches of lateral Striate Arteries as observed with nomarski optics
1996Co-Authors: C J GouveiaAbstract:Lateral Striate Arteries were dissected from the fixed brains of 6 patients of increasing age. Small branches of Arteries were observed – unprocessed and unstained – by Nomarski optics. Among the find
Hyun-seung Kang - One of the best experts on this subject based on the ideXlab platform.
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evaluation of the lenticuloStriate Arteries with rotational angiography and 3d reconstruction
2005Co-Authors: Hyun-seung Kang, Moon Hee Han, Bae Ju Kwon, O-ki Kwon, Sung Hyun Kim, Kee-hyun ChangAbstract:BACKGROUND AND PURPOSE: Anatomic evaluation of the lenticuloStriate Arteries (LSAs) is important, especially in cases of surgical or endovascular treatment, but biplanar angiography provides limited information. We analyzed the LSAs with rotational angiography (RA) and 3D reconstruction and compared the findings with those of previous autopsy studies. METHODS: We retrospectively reviewed the LSAs on 3D reconstructed RA images (200 sides in 159 cases) to analyze their origin, course, and supplying territories. The angiographic configurations of the LSAs were classified by using the scheme devised by Yasargil. RESULTS: LSAs from the anterior cerebral artery were demonstrated on 140 sides (70%). They originated from the A1 segment in 59 sides, from the A1-A2 junction on 41 sides, and from the A2 segment on 35 sides. They arose as a single trunk and ended as the most medial and anterior perforators in most cases. Arteries from the middle cerebral artery (MCA) were demonstrated on 190 sides (95%). They originated from the M1 segment on 131 sides, from the MCA bifurcation on 26 sides, and from the M2 segment on 33 sides; notably, all LSAs arising from the M2 segment originated from the superior division. In terms of configuration, we identified four major and 11 minor types. The most frequent LSA type was the combination of medial and lateral distal Striate Arteries, which comprised 53 sides (28%). CONCLUSION: Analysis of LSAs with RA and 3D reconstructed images may provide useful information in patients with cerebrovascular diseases, especially before surgical and endovascular treatment.
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Evaluation of the lenticuloStriate Arteries with rotational angiography and 3D reconstruction
2005Co-Authors: Hyun-seung Kang, Moon Hee Han, Bae Ju Kwon, O-ki Kwon, Sung Hyun Kim, Kee-hyun ChangAbstract:is important, especially in cases of surgical or endovascular treatment, but biplanar angiogra-phy provides limited information. We analyzed the LSAs with rotational angiography (RA) and 3D reconstruction and compared the findings with those of previous autopsy studies. METHODS:We retrospectively reviewed the LSAs on 3D reconstructed RA images (200 sides in 159 cases) to analyze their origin, course, and supplying territories. The angiographic configurations of the LSAs were classified by using the scheme devised by Yasargil. RESULTS: LSAs from the anterior cerebral artery were demonstrated on 140 sides (70%). They originated from the A1 segment in 59 sides, from the A1-A2 junction on 41 sides, and from the A2 segment on 35 sides. They arose as a single trunk and ended as the most medial and anterior perforators in most cases. Arteries from the middle cerebral artery (MCA) were demonstrated on 190 sides (95%). They originated from the M1 segment on 131 sides, from the MCA bifurcation on 26 sides, and from the M2 segment on 33 sides; notably, all LSAs arising from the M2 segment originated from the superior division. In terms of configuration, we identified four major and 11 minor types. The most frequent LSA type was the combination of medial and lateral distal Striate Arteries, which comprised 53 sides (28%)
Vincent Prinz - One of the best experts on this subject based on the ideXlab platform.
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lateral chronic cranial window preparation enables in vivo observation following distal middle cerebral artery occlusion in mice
2016Co-Authors: Simon Bayerl, Melina Nieminenkelha, Thomas Broggini, Peter Vajkoczy, Vincent PrinzAbstract:Focal cerebral ischemia (i.e., ischemic stroke) may cause major brain injury, leading to a severe loss of neuronal function and consequently to a host of motor and cognitive disabilities. Its high prevalence poses a serious health burden, as stroke is among the principal causes of long-term disability and death worldwide1. Recovery of neuronal function is, in most cases, only partial. So far, treatment options are very limited, in particular due to the narrow time window for thrombolysis2,3. Determining methods to accelerate recovery from stroke remains a prime medical goal; however, this has been hampered by insufficient mechanistic insights into the recovery process. Experimental stroke researchers frequently employ rodent models of focal cerebral ischemia. Beyond the acute phase, stroke research is increasingly focused on the sub-acute and chronic phase following cerebral ischemia. Most stroke researchers apply permanent or transient occlusion of the MCA in mice or rats. In patients, occlusions of the MCA are among the most frequent causes of ischemic stroke4. Besides proximal occlusion of the MCA using the filament model, surgical occlusion of the distal MCA is probably the most frequently used model in experimental stroke research5. Occlusion of a distal (to the branching of the lenticulo-Striate Arteries) MCA branch typically spares the striatum and primarily affects the neocortex. Vessel occlusion can be permanent or transient. High reproducibility of lesion volume and very low mortality rates with respect to the long-term outcome are the main advantages of this model. Here, we demonstrate how to perform a chronic cranial window (CW) preparation lateral to the sagittal sinus, and afterwards how to surgically induce a distal stroke underneath the window using a craniotomy approach. This approach can be applied for sequential imaging of acute and chronic changes following ischemia via epi-illuminating, confocal laser scanning, and two-photon intravital microscopy.
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Video Article Modeling Stroke in Mice- Middle Cerebral Artery Occlusion with the Filament Model
2016Co-Authors: Odilo Engel, Sabine Kolodziej, Ulrich Dirnagl, Vincent PrinzAbstract:Exp. (47), e2423, doi:10.3791/2423 (2011). Stroke is among the most frequent causes of death and adult disability, especially in highly developed countries. However, treatment options to date are very limited. To meet the need for novel therapeutic approaches, experimental stroke research frequently employs rodent models of focal cerebral ischaemia. Most researchers use permanent or transient occlusion of the middle cerebral artery (MCA) in mice or rats. Proximal occlusion of the middle cerebral artery (MCA) via the intraluminal suture technique (so called filament or suture model) is probably the most frequently used model in experimental stroke research. The intraluminal MCAO model offers the advantage of inducing reproducible transient or permanent ischaemia of the MCA territory in a relatively non-invasive manner. Intraluminal approaches interrupt the blood flow of the entire territory of this artery. Filament occlusion thus arrests flow proximal to the lenticulo-Striate Arteries, which supply the basal ganglia. Filament occlusion of the MCA results in reproducible lesions in the cortex and striatum and can be either permanent or transient. In contrast, models inducing distal (to the branching of the lenticulo-Striate Arteries) MCA occlusion typically spare the striatum and primarily involve the neocortex. In addition these models do require craniectomy. In the model demonstrated in this article, a silicon coated filament is introduced into the common carotid artery and advanced along the internal carotid artery into the Circle of Willis, where it blocks the origin of the middle cerebra
O-ki Kwon - One of the best experts on this subject based on the ideXlab platform.
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evaluation of the lenticuloStriate Arteries with rotational angiography and 3d reconstruction
2005Co-Authors: Hyun-seung Kang, Moon Hee Han, Bae Ju Kwon, O-ki Kwon, Sung Hyun Kim, Kee-hyun ChangAbstract:BACKGROUND AND PURPOSE: Anatomic evaluation of the lenticuloStriate Arteries (LSAs) is important, especially in cases of surgical or endovascular treatment, but biplanar angiography provides limited information. We analyzed the LSAs with rotational angiography (RA) and 3D reconstruction and compared the findings with those of previous autopsy studies. METHODS: We retrospectively reviewed the LSAs on 3D reconstructed RA images (200 sides in 159 cases) to analyze their origin, course, and supplying territories. The angiographic configurations of the LSAs were classified by using the scheme devised by Yasargil. RESULTS: LSAs from the anterior cerebral artery were demonstrated on 140 sides (70%). They originated from the A1 segment in 59 sides, from the A1-A2 junction on 41 sides, and from the A2 segment on 35 sides. They arose as a single trunk and ended as the most medial and anterior perforators in most cases. Arteries from the middle cerebral artery (MCA) were demonstrated on 190 sides (95%). They originated from the M1 segment on 131 sides, from the MCA bifurcation on 26 sides, and from the M2 segment on 33 sides; notably, all LSAs arising from the M2 segment originated from the superior division. In terms of configuration, we identified four major and 11 minor types. The most frequent LSA type was the combination of medial and lateral distal Striate Arteries, which comprised 53 sides (28%). CONCLUSION: Analysis of LSAs with RA and 3D reconstructed images may provide useful information in patients with cerebrovascular diseases, especially before surgical and endovascular treatment.
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Evaluation of the lenticuloStriate Arteries with rotational angiography and 3D reconstruction
2005Co-Authors: Hyun-seung Kang, Moon Hee Han, Bae Ju Kwon, O-ki Kwon, Sung Hyun Kim, Kee-hyun ChangAbstract:is important, especially in cases of surgical or endovascular treatment, but biplanar angiogra-phy provides limited information. We analyzed the LSAs with rotational angiography (RA) and 3D reconstruction and compared the findings with those of previous autopsy studies. METHODS:We retrospectively reviewed the LSAs on 3D reconstructed RA images (200 sides in 159 cases) to analyze their origin, course, and supplying territories. The angiographic configurations of the LSAs were classified by using the scheme devised by Yasargil. RESULTS: LSAs from the anterior cerebral artery were demonstrated on 140 sides (70%). They originated from the A1 segment in 59 sides, from the A1-A2 junction on 41 sides, and from the A2 segment on 35 sides. They arose as a single trunk and ended as the most medial and anterior perforators in most cases. Arteries from the middle cerebral artery (MCA) were demonstrated on 190 sides (95%). They originated from the M1 segment on 131 sides, from the MCA bifurcation on 26 sides, and from the M2 segment on 33 sides; notably, all LSAs arising from the M2 segment originated from the superior division. In terms of configuration, we identified four major and 11 minor types. The most frequent LSA type was the combination of medial and lateral distal Striate Arteries, which comprised 53 sides (28%)