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Jose M Revuelta - One of the best experts on this subject based on the ideXlab platform.
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durability of the carpentier edwards porcine bioprosthesis role of age and valve position
The Annals of Thoracic Surgery, 1995Co-Authors: Jose M Bernal, Jose M Rabasa, Raul Lopez, Francisco J Nistal, Roberto Muniz, Jose M RevueltaAbstract:The durability (Structural Deterioration-free interval) after valve implantation with the first-generation Carpentier-Edwards porcine bioprosthesis has been investigated. From 1978 through 1984, 420 patients (175 male, 245 female) underwent valve replacement with the Carpentier-Edwards standard bioprosthesis. Mean age was 50.6 years (range, 13 to 77 years). Isolated mitral valve replacement (MVR) was performed in 198 patients (47.1%), aortic valve replacement (AVR) in 136 (32.4%), and double valve replacement (DVR) in 86 (20.5%). Hospital mortality was 32 patients (7.6%), 7.5% for MVR, 5.1% for AVR, and 11.6% for DVR. Mean follow-up was 10.8 years (range, 9 to 15 years) and is 96.2% completed. Reoperation for Structural Deterioration was required in 143 patients. Actuarial curve free from Structural Deterioration at 15 years is 33.0% ± 6.5% for MVR, 62.0% ± 5.1% for AVR, and 44.2% ± 8.2% for DVR ( p = 0.03). Durability of the CE bioprosthesis for MVR was 101.6 ± 34.5 months, 92.9 ± 26.4 for AVR, and 84.3 ± 25.3 for DVR ( p = not significant). The regression logistic analysis between age at the time of surgery and durability of the bioprosthesis showed no correlation for the MVR group, but with the following predictive formula for AVR and DVR groups of patients older than 30 years: durability=46.05 + 0.818 × age, for AVR (r 2 = 0.43); durability=15.81 + 1.122 × age, for DVR (r 2 = 0.52). In conclusion, we have found a significant difference in the behavior of the CE porcine bioprosthesis between the mitral and aortic position. According to the linear regression analysis, age appears to be an important predictive factor for bioprosthetic durability in the group of patients with isolated aortic or double valve replacement.
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durability of the carpentier edwards porcine bioprosthesis role of age and valve position discussion
The Annals of Thoracic Surgery, 1995Co-Authors: Jose M Bernal, Jose M Rabasa, Raul Lopez, Roberto Muniz, Jose M Revuelta, J F Nistal, L H CohnAbstract:The durability (Structural Deterioration-free interval) after valve implantation with the first-generation Carpentier-Edwards porcine bioprosthesis has been investigated. From 1978 through 1984, 420 patients (175 male, 245 female) underwent valve replacement with the Carpentier-Edwards standard bioprosthesis. Mean age was 50.6 years (range, 13 to 77 years). Isolated mitral valve replacement (MVR) was performed in 198 patients (47.1%), aortic valve replacement (AVR) in 136 (32.4%), and double valve replacement (DVR) in 86 (20.5%). Hospital mortality was 32 patients (7.6%), 7.5% for MVR, 5.1% for AVR, and 11.6% for DVR. Mean follow-up was 10.8 years (range, 9 to 15 years) and is 96.2% completed. Reoperation for Structural Deterioration was required in 143 patients. Actuarial curve free from Structural Deterioration at 15 years is 33.0% ± 6.5% for MVR, 62.0% ± 5.1% for AVR, and 44.2% ± 8.2% for DVR (p = 0.03). Durability of the CE bioprosthesis for MVR was 101.6 ± 34.5 months, 92.9 ± 26.4 for AVR, and 84.3 ± 25.3 for DVR (p = not significant). The regression logistic analysis between age at the time of surgery and durability of the bioprosthesis showed no correlation for the MVR group, but with the following predictive formula for AVR and DVR groups of patients older than 30 years : durability = 46.05 + 0.818 x age, for AVR (r 2 = 0.43) ; durability = 15.81 + 1.122 x age, for DVR (r 2 = 0.52). In conclusion, we have found a significant difference in the behavior of the CE porcine bioprosthesis between the mitral and aortic position. According to the linear regression analysis, age appears to be an important predictive factor for bioprosthetic durability in the group of patients with isolated aortic or double valve replacement.
Jose M Bernal - One of the best experts on this subject based on the ideXlab platform.
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durability of the carpentier edwards porcine bioprosthesis role of age and valve position
The Annals of Thoracic Surgery, 1995Co-Authors: Jose M Bernal, Jose M Rabasa, Raul Lopez, Francisco J Nistal, Roberto Muniz, Jose M RevueltaAbstract:The durability (Structural Deterioration-free interval) after valve implantation with the first-generation Carpentier-Edwards porcine bioprosthesis has been investigated. From 1978 through 1984, 420 patients (175 male, 245 female) underwent valve replacement with the Carpentier-Edwards standard bioprosthesis. Mean age was 50.6 years (range, 13 to 77 years). Isolated mitral valve replacement (MVR) was performed in 198 patients (47.1%), aortic valve replacement (AVR) in 136 (32.4%), and double valve replacement (DVR) in 86 (20.5%). Hospital mortality was 32 patients (7.6%), 7.5% for MVR, 5.1% for AVR, and 11.6% for DVR. Mean follow-up was 10.8 years (range, 9 to 15 years) and is 96.2% completed. Reoperation for Structural Deterioration was required in 143 patients. Actuarial curve free from Structural Deterioration at 15 years is 33.0% ± 6.5% for MVR, 62.0% ± 5.1% for AVR, and 44.2% ± 8.2% for DVR ( p = 0.03). Durability of the CE bioprosthesis for MVR was 101.6 ± 34.5 months, 92.9 ± 26.4 for AVR, and 84.3 ± 25.3 for DVR ( p = not significant). The regression logistic analysis between age at the time of surgery and durability of the bioprosthesis showed no correlation for the MVR group, but with the following predictive formula for AVR and DVR groups of patients older than 30 years: durability=46.05 + 0.818 × age, for AVR (r 2 = 0.43); durability=15.81 + 1.122 × age, for DVR (r 2 = 0.52). In conclusion, we have found a significant difference in the behavior of the CE porcine bioprosthesis between the mitral and aortic position. According to the linear regression analysis, age appears to be an important predictive factor for bioprosthetic durability in the group of patients with isolated aortic or double valve replacement.
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durability of the carpentier edwards porcine bioprosthesis role of age and valve position discussion
The Annals of Thoracic Surgery, 1995Co-Authors: Jose M Bernal, Jose M Rabasa, Raul Lopez, Roberto Muniz, Jose M Revuelta, J F Nistal, L H CohnAbstract:The durability (Structural Deterioration-free interval) after valve implantation with the first-generation Carpentier-Edwards porcine bioprosthesis has been investigated. From 1978 through 1984, 420 patients (175 male, 245 female) underwent valve replacement with the Carpentier-Edwards standard bioprosthesis. Mean age was 50.6 years (range, 13 to 77 years). Isolated mitral valve replacement (MVR) was performed in 198 patients (47.1%), aortic valve replacement (AVR) in 136 (32.4%), and double valve replacement (DVR) in 86 (20.5%). Hospital mortality was 32 patients (7.6%), 7.5% for MVR, 5.1% for AVR, and 11.6% for DVR. Mean follow-up was 10.8 years (range, 9 to 15 years) and is 96.2% completed. Reoperation for Structural Deterioration was required in 143 patients. Actuarial curve free from Structural Deterioration at 15 years is 33.0% ± 6.5% for MVR, 62.0% ± 5.1% for AVR, and 44.2% ± 8.2% for DVR (p = 0.03). Durability of the CE bioprosthesis for MVR was 101.6 ± 34.5 months, 92.9 ± 26.4 for AVR, and 84.3 ± 25.3 for DVR (p = not significant). The regression logistic analysis between age at the time of surgery and durability of the bioprosthesis showed no correlation for the MVR group, but with the following predictive formula for AVR and DVR groups of patients older than 30 years : durability = 46.05 + 0.818 x age, for AVR (r 2 = 0.43) ; durability = 15.81 + 1.122 x age, for DVR (r 2 = 0.52). In conclusion, we have found a significant difference in the behavior of the CE porcine bioprosthesis between the mitral and aortic position. According to the linear regression analysis, age appears to be an important predictive factor for bioprosthetic durability in the group of patients with isolated aortic or double valve replacement.
Dominique Himbert - One of the best experts on this subject based on the ideXlab platform.
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assessment of long term Structural Deterioration of transcatheter aortic bioprosthetic valves using the new european definition
Circulation-cardiovascular Interventions, 2019Co-Authors: Eric Durand, Anastasia Sokoloff, Marina Urenaalcazar, Bernard Chevalier, Stephan Chassaing, Romain Didier, Christophe Tron, Pierreyves Litzler, Claire Bouleti, Dominique HimbertAbstract:Background: The durability of transcatheter aortic bioprosthetic valves is a crucial issue, but data are scarce, especially beyond 5 years of follow-up. We aimed to assess long-term (7 years) struc...
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assessment of long term Structural Deterioration of transcatheter aortic bioprosthetic valves using standardized new european definitions a multicenter french study
Archives of Cardiovascular Diseases Supplements, 2019Co-Authors: Anastasia Sokoloff, Dominique Himbert, Eric Durand, Marina Urenaalcazar, Bernard Chevalier, Stephan Chassaing, Romain Didier, Pierreyves Litzler, T Hovasse, Olivier BarAbstract:Background In the context of extension of transcatheter aortic valve implantation (TAVI) indications to lower-risk patients, long-term durability of transcatheter aortic bioprosthetic valves (TABV) is a crucial issue. There is a paucity of data, especially beyond 5 years of follow-up. Recently, new definitions have been proposed to assess Structural valve Deterioration (SVD) and bioprosthetic valve failure (BVF). Purpose We aim to assess long-term SVD and BVF of TABV using standardized new definitions. Methods All TAVI patients implanted between 2002 and 2011 in 5 French centers were included. One month and last available echocardiographic follow-up were used to assess SVD and BVF of according to the new European criteria. Competing-risk analysis was used to assess SVD and BVF incidence. Results From 2002 to 2011, 1403 patients were included. Mean age and logistic EuroSCORE were 82.6 ± 7.5 years and 21.3 ± 7.5%. Mean duration follow-up was 3.6 ± 2.1 years with a maximum of 10.2 years. Survival rates were 83.5% (95% CI: 81.4–85.5), 18.6% (95% CI: 15.3–21.8) and 8.0% (95% CI: 1.9–14.2) at 1, 7 and 10 years, respectively. BVF occurred in 18 patients of whom 5 required reoperation with a mean delay of 5.5 ± 1.3 years. Incidence of BVF was 2.2% (95% CI: 1.2–3.7) and 3.4 (95% CI: 1.7–5.9) at 7 and 10 years, respectively. Among 589 patients eligible for the SVD analysis, 41 had moderate SVD and 15 had severe SVD. Incidence of moderate SVD was 9.2% (95% CI: 6.5–12.6) and 16.6% (95% CI: 9.1–26.0) at 7 and 10 years, respectively. Incidence of severe SVD was 4.4% (95% CI: 2.2–7.9) and 8.0% (95% CI: 3.3–15.2) at 7 and 10 years, respectively. Conclusions Despite the low survival rates of the early treated TAVI population in France, we believe reporting the longest follow-up available. Our study does not highlight any alarm signal concerning late durability of TABV. Further studies are warranted to assess long-term durability of TABV particularly in younger and lower risk-patients.
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reversible edwards sapien xt dysfunction due to prosthesis thrombosis presenting as early Structural Deterioration
Journal of the American College of Cardiology, 2013Co-Authors: Azeem Latib, David Messikazeitoun, Francesco Maisano, Dominique Himbert, Eustachio Agricola, Eric Brochet, Ottavio Alfieri, Antonio Colombo, Alec VahanianAbstract:To the Editor: Transcatheter aortic valve implantation (TAVI) continues to penetrate into daily practice supported by increasing data demonstrating efficacy and safety on the short- to medium-term but the long-term durability of transcatheter heart valves (THV) remains unknown. In this report, we
L H Cohn - One of the best experts on this subject based on the ideXlab platform.
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durability of the carpentier edwards porcine bioprosthesis role of age and valve position discussion
The Annals of Thoracic Surgery, 1995Co-Authors: Jose M Bernal, Jose M Rabasa, Raul Lopez, Roberto Muniz, Jose M Revuelta, J F Nistal, L H CohnAbstract:The durability (Structural Deterioration-free interval) after valve implantation with the first-generation Carpentier-Edwards porcine bioprosthesis has been investigated. From 1978 through 1984, 420 patients (175 male, 245 female) underwent valve replacement with the Carpentier-Edwards standard bioprosthesis. Mean age was 50.6 years (range, 13 to 77 years). Isolated mitral valve replacement (MVR) was performed in 198 patients (47.1%), aortic valve replacement (AVR) in 136 (32.4%), and double valve replacement (DVR) in 86 (20.5%). Hospital mortality was 32 patients (7.6%), 7.5% for MVR, 5.1% for AVR, and 11.6% for DVR. Mean follow-up was 10.8 years (range, 9 to 15 years) and is 96.2% completed. Reoperation for Structural Deterioration was required in 143 patients. Actuarial curve free from Structural Deterioration at 15 years is 33.0% ± 6.5% for MVR, 62.0% ± 5.1% for AVR, and 44.2% ± 8.2% for DVR (p = 0.03). Durability of the CE bioprosthesis for MVR was 101.6 ± 34.5 months, 92.9 ± 26.4 for AVR, and 84.3 ± 25.3 for DVR (p = not significant). The regression logistic analysis between age at the time of surgery and durability of the bioprosthesis showed no correlation for the MVR group, but with the following predictive formula for AVR and DVR groups of patients older than 30 years : durability = 46.05 + 0.818 x age, for AVR (r 2 = 0.43) ; durability = 15.81 + 1.122 x age, for DVR (r 2 = 0.52). In conclusion, we have found a significant difference in the behavior of the CE porcine bioprosthesis between the mitral and aortic position. According to the linear regression analysis, age appears to be an important predictive factor for bioprosthetic durability in the group of patients with isolated aortic or double valve replacement.
Raul Lopez - One of the best experts on this subject based on the ideXlab platform.
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durability of the carpentier edwards porcine bioprosthesis role of age and valve position
The Annals of Thoracic Surgery, 1995Co-Authors: Jose M Bernal, Jose M Rabasa, Raul Lopez, Francisco J Nistal, Roberto Muniz, Jose M RevueltaAbstract:The durability (Structural Deterioration-free interval) after valve implantation with the first-generation Carpentier-Edwards porcine bioprosthesis has been investigated. From 1978 through 1984, 420 patients (175 male, 245 female) underwent valve replacement with the Carpentier-Edwards standard bioprosthesis. Mean age was 50.6 years (range, 13 to 77 years). Isolated mitral valve replacement (MVR) was performed in 198 patients (47.1%), aortic valve replacement (AVR) in 136 (32.4%), and double valve replacement (DVR) in 86 (20.5%). Hospital mortality was 32 patients (7.6%), 7.5% for MVR, 5.1% for AVR, and 11.6% for DVR. Mean follow-up was 10.8 years (range, 9 to 15 years) and is 96.2% completed. Reoperation for Structural Deterioration was required in 143 patients. Actuarial curve free from Structural Deterioration at 15 years is 33.0% ± 6.5% for MVR, 62.0% ± 5.1% for AVR, and 44.2% ± 8.2% for DVR ( p = 0.03). Durability of the CE bioprosthesis for MVR was 101.6 ± 34.5 months, 92.9 ± 26.4 for AVR, and 84.3 ± 25.3 for DVR ( p = not significant). The regression logistic analysis between age at the time of surgery and durability of the bioprosthesis showed no correlation for the MVR group, but with the following predictive formula for AVR and DVR groups of patients older than 30 years: durability=46.05 + 0.818 × age, for AVR (r 2 = 0.43); durability=15.81 + 1.122 × age, for DVR (r 2 = 0.52). In conclusion, we have found a significant difference in the behavior of the CE porcine bioprosthesis between the mitral and aortic position. According to the linear regression analysis, age appears to be an important predictive factor for bioprosthetic durability in the group of patients with isolated aortic or double valve replacement.
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durability of the carpentier edwards porcine bioprosthesis role of age and valve position discussion
The Annals of Thoracic Surgery, 1995Co-Authors: Jose M Bernal, Jose M Rabasa, Raul Lopez, Roberto Muniz, Jose M Revuelta, J F Nistal, L H CohnAbstract:The durability (Structural Deterioration-free interval) after valve implantation with the first-generation Carpentier-Edwards porcine bioprosthesis has been investigated. From 1978 through 1984, 420 patients (175 male, 245 female) underwent valve replacement with the Carpentier-Edwards standard bioprosthesis. Mean age was 50.6 years (range, 13 to 77 years). Isolated mitral valve replacement (MVR) was performed in 198 patients (47.1%), aortic valve replacement (AVR) in 136 (32.4%), and double valve replacement (DVR) in 86 (20.5%). Hospital mortality was 32 patients (7.6%), 7.5% for MVR, 5.1% for AVR, and 11.6% for DVR. Mean follow-up was 10.8 years (range, 9 to 15 years) and is 96.2% completed. Reoperation for Structural Deterioration was required in 143 patients. Actuarial curve free from Structural Deterioration at 15 years is 33.0% ± 6.5% for MVR, 62.0% ± 5.1% for AVR, and 44.2% ± 8.2% for DVR (p = 0.03). Durability of the CE bioprosthesis for MVR was 101.6 ± 34.5 months, 92.9 ± 26.4 for AVR, and 84.3 ± 25.3 for DVR (p = not significant). The regression logistic analysis between age at the time of surgery and durability of the bioprosthesis showed no correlation for the MVR group, but with the following predictive formula for AVR and DVR groups of patients older than 30 years : durability = 46.05 + 0.818 x age, for AVR (r 2 = 0.43) ; durability = 15.81 + 1.122 x age, for DVR (r 2 = 0.52). In conclusion, we have found a significant difference in the behavior of the CE porcine bioprosthesis between the mitral and aortic position. According to the linear regression analysis, age appears to be an important predictive factor for bioprosthetic durability in the group of patients with isolated aortic or double valve replacement.
