Subbundles

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E Ballico - One of the best experts on this subject based on the ideXlab platform.

George H Hitching - One of the best experts on this subject based on the ideXlab platform.

  • counting maximal lagrangian Subbundles over an algebraic curve
    Journal of Geometry and Physics, 2021
    Co-Authors: Daewoong Cheong, Insong Choe, George H Hitching
    Abstract:

    Abstract Let C be a smooth projective curve and W a symplectic bundle over C. Let L Q e ( W ) be the Lagrangian Quot scheme parametrizing Lagrangian subsheaves E ⊂ W of degree e. We give a closed formula for intersection numbers on L Q e ( W ) . As a special case, for g ≥ 2 , we compute the number of Lagrangian Subbundles of maximal degree of a general stable symplectic bundle, when this is finite. This is a symplectic analogue of Holla's enumeration of maximal Subbundles in [14] .

  • counting maximal lagrangian Subbundles over an algebraic curve
    arXiv: Algebraic Geometry, 2019
    Co-Authors: Daewoong Cheong, Insong Choe, George H Hitching
    Abstract:

    Let $C$ be a smooth projective curve and $W$ a symplectic bundle over $C$. Let $LQ_e (W)$ be the Lagrangian Quot scheme parametrizing Lagrangian subsheaves $E \subset W$ of degree $e$. We give a closed formula for intersection numbers on $LQ_e (W)$. As a special case, for $g \ge 2$, we compute the number of Lagrangian Subbundles of maximal degree of a general stable symplectic bundle, when this is finite. This is a symplectic analogue of Holla's enumeration of maximal Subbundles in [13].

  • non defectivity of grassmannian bundles over a curve
    arXiv: Algebraic Geometry, 2015
    Co-Authors: Insong Choe, George H Hitching
    Abstract:

    Let Gr(2, E) be the Grassmann bundle of two-planes associated to a general bundle E over a curve X. We prove that an embedding of Gr(2, E) by a certain twist of the relative Pl\"ucker map is not secant defective. This yields a new and more geometric proof of the Hirschowitz-type bound on the Lagrangian Segre invariant for orthogonal bundles over X, analogous to those given for vector bundles and symplectic bundles in [2, 3]. From the non-defectivity we also deduce an interesting feature of a general orthogonal bundle over X, contrasting with the classical and symplectic cases: Any maximal Lagrangian subbundle intersects at least one other maximal Lagrangian subbundle in positive rank.

  • lagrangian Subbundles of orthogonal bundles of odd rank over an algebraic curve
    arXiv: Algebraic Geometry, 2014
    Co-Authors: Insong Choe, George H Hitching
    Abstract:

    An orthogonal bundle over a curve has an isotropic Segre invariant determined by the maximal degree of a Lagrangian subbundle. This invariant, and the induced stratifications on moduli spaces of orthogonal bundles, were studied for bundles of even rank in [4]. In this paper, we obtain analogous results for bundles of odd rank. We obtain a sharp upper bound on the isotropic Segre invariant. We show the irreducibility of the induced strata on the moduli spaces of orthogonal bundles of odd rank, and compute their dimensions. As a key ingredient of the proofs, we study the correspondence between Lagrangian Subbundles of orthogonal bundles of even and odd rank.

  • lagrangian Subbundles of symplectic bundles over a curve
    Mathematical Proceedings of the Cambridge Philosophical Society, 2012
    Co-Authors: Insong Choe, George H Hitching
    Abstract:

    A symplectic bundle over an algebraic curve has a natural invariant s Lag determined by the maximal degree of its Lagrangian Subbundles. This can be viewed as a generalization of the classical Segre invariants of a vector bundle. We give a sharp upper bound on s Lag which is analogous to the Hirschowitz bound on the classical Segre invariants. Furthermore, we study the stratifications induced by s Lag on moduli spaces of symplectic bundles, and get a full picture for the case of rank four.

Viola Vogel - One of the best experts on this subject based on the ideXlab platform.

  • Vogel V (2008) How force might activate talin’s vinculin binding sites: SMD reveals a structural mechanism. PLoS Comput Biol 4: e24
    2016
    Co-Authors: Vesa P. Hytönen, Viola Vogel
    Abstract:

    Upon cell adhesion, talin physically couples the cytoskeleton via integrins to the extracellular matrix, and subsequent vinculin recruitment is enhanced by locally applied tensile force. Since the vinculin binding (VB) sites are buried in the talin rod under equilibrium conditions, the structural mechanism of how vinculin binding to talin is force-activated remains unknown. Taken together with experimental data, a biphasic vinculin binding model, as derived from steered molecular dynamics, provides high resolution structural insights how tensile mechanical force applied to the talin rod fragment (residues 486–889 constituting helices H1–H12) might activate the VB sites. Fragmentation of the rod into three helix Subbundles is prerequisite to the sequential exposure of VB helices to water. Finally, unfolding of a VB helix into a completely stretched polypeptide might inhibit further binding of vinculin. The first events in fracturing the H1– H12 rods of talin1 and talin2 in Subbundles are similar. The proposed force-activated a-helix swapping mechanism by which vinculin binding sites in talin rods are exposed works distinctly different from that of other force-activated bonds, including catch bonds

  • How force might activate talin's vinculin binding sites: SMD reveals a structural mechanism
    PLoS Computational Biology, 2008
    Co-Authors: Vesa P. Hytönen, Viola Vogel
    Abstract:

    Upon cell adhesion, talin physically couples the cytoskeleton via integrins to the extracellular matrix, and subsequent vinculin recruitment is enhanced by locally applied tensile force. Since the vinculin binding (VB) sites are buried in the talin rod under equilibrium conditions, the structural mechanism of how vinculin binding to talin is force-activated remains unknown. Taken together with experimental data, a biphasic vinculin binding model, as derived from steered molecular dynamics, provides high resolution structural insights how tensile mechanical force applied to the talin rod fragment (residues 486-889 constituting helices H1-H12) might activate the VB sites. Fragmentation of the rod into three helix Subbundles is prerequisite to the sequential exposure of VB helices to water. Finally, unfolding of a VB helix into a completely stretched polypeptide might inhibit further binding of vinculin. The first events in fracturing the H1-H12 rods of talin1 and talin2 in Subbundles are similar. The proposed force-activated alpha-helix swapping mechanism by which vinculin binding sites in talin rods are exposed works distinctly different from that of other force-activated bonds, including catch bonds.

Vesa P. Hytönen - One of the best experts on this subject based on the ideXlab platform.

  • How force might activate talin's vinculin binding sites: SMD reveals a structural mechanism
    PLoS Computational Biology, 2008
    Co-Authors: Vesa P. Hytönen, Viola Vogel
    Abstract:

    Upon cell adhesion, talin physically couples the cytoskeleton via integrins to the extracellular matrix, and subsequent vinculin recruitment is enhanced by locally applied tensile force. Since the vinculin binding (VB) sites are buried in the talin rod under equilibrium conditions, the structural mechanism of how vinculin binding to talin is force-activated remains unknown. Taken together with experimental data, a biphasic vinculin binding model, as derived from steered molecular dynamics, provides high resolution structural insights how tensile mechanical force applied to the talin rod fragment (residues 486-889 constituting helices H1-H12) might activate the VB sites. Fragmentation of the rod into three helix Subbundles is prerequisite to the sequential exposure of VB helices to water. Finally, unfolding of a VB helix into a completely stretched polypeptide might inhibit further binding of vinculin. The first events in fracturing the H1-H12 rods of talin1 and talin2 in Subbundles are similar. The proposed force-activated alpha-helix swapping mechanism by which vinculin binding sites in talin rods are exposed works distinctly different from that of other force-activated bonds, including catch bonds.

Simion Filip - One of the best experts on this subject based on the ideXlab platform.

  • Semisimplicity and rigidity of the Kontsevich-Zorich cocycle
    Inventiones mathematicae, 2016
    Co-Authors: Simion Filip
    Abstract:

    We prove that invariant Subbundles of the Kontsevich-Zorich cocycle respect the Hodge structure. In particular, we establish a version of Deligne semisimplicity in this context. This implies that invariant Subbundles must vary polynomially on affine manifolds. All results apply to tensor powers of the cocycle and this implies that the measurable and real-analytic algebraic hulls coincide. We also prove that affine manifolds typically parametrize Jacobians with non-trivial endomorphisms. If the field of affine definition is larger than $$\mathbb {Q}$$ Q , then a factor has real multiplication. The tools involve curvature properties of the Hodge bundles and estimates from random walks. In the appendix, we explain how methods from ergodic theory imply some of the global consequences of Schmid’s work on variations of Hodge structures. We also derive the Kontsevich-Forni formula using differential geometry.

  • semisimplicity and rigidity of the kontsevich zorich cocycle
    arXiv: Dynamical Systems, 2013
    Co-Authors: Simion Filip
    Abstract:

    We prove that invariant Subbundles of the Kontsevich-Zorich cocycle respect the Hodge structure. In particular, we establish a version of Deligne semisimplicity in this context. This implies that invariant Subbundles must vary polynomially on affine manifolds. All results apply to tensor powers of the cocycle and this implies that the measurable and real-analytic algebraic hulls coincide. We also prove that affine manifolds parametrize Jacobians with non-trivial endomorphisms. Typically a factor has real multiplication. The tools involve curvature properties of the Hodge bundles and estimates from random walks. In the appendix, we explain how methods from ergodic theory imply some of the global consequences of Schmid's work on variations of Hodge structures. We also derive the Kontsevich-Forni formula using differential geometry.