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Marc Remacle - One of the best experts on this subject based on the ideXlab platform.
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Recurrent respiratory distress and idiopathic Subglottic Stenosis: what treatment?
Archives françaises de pédiatrie, 1993Co-Authors: Eddy Bodart, De Bilderling G, Alain Mayné, Georges Lawson, Marc RemacleAbstract:Idiopathic Subglottic Stenosis is a rare cause of acute respiratory distress, that is difficult to treat (corticosteroids, tracheotomy). A nine-year-old boy presented with acute respiratory distress due to tracheal Stenosis. The symptoms recurred after the endotracheal inflammatory membranes had been removed with forceps, despite 6-months of degressive corticotherapy. Absence of other causes of tracheal Stenosis and biopsies led to diagnosis of idiopathic Subglottic Stenosis. The patient was treated by CO2 laser followed by degressive corticotherapy. The respiratory distress recurred within 3 months of discontinuing corticosteroids, requiring two further CO2 laser treatments. The patient became corticodependent. CO2 laser is an effective, wise alternative treatment of acute respiratory distress due to idiopathic Subglottic Stenosis that can be repeated if necessary.
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Treatment of Recurrent Respiratory-distress Due To Idiopathic Subglottic Stenosis
Archives françaises de pédiatrie, 1993Co-Authors: Eddy Bodart, G. Debilderling, Alain Mayné, Georges Lawson, Marc RemacleAbstract:Background. Idiopathic Subglottic Stenosis is a rare cause of acute respiratory distress, that is difficult to treat (corticosteroids, tracheotomy). Case report. A nine-year-old boy presented with acute respiratory distress due to tracheal Stenosis. The symptoms recurred after the endotracheal inflammatory membranes had been removed with forceps, despite 6-months of degressive corticotherapy. Absence of other causes of tracheal Stenosis and biopsies led to diagnosis of idiopathic Subglottic Stenosis. The patient was treated by CO2 laser followed by degressive corticotherapy. The respiratory distress recurred within 3 months of discontinuing corticosteroids, requiring two further CO2 laser treatments. The patient became corticodependent. Conclusions. CO2 laser is an effective, wise alternative treatment of acute respiratory distress due to idiopathic Subglottic Stenosis that can be repeated if necessary.
Robert R. Lorenz - One of the best experts on this subject based on the ideXlab platform.
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Subglottic Stenosis a ten year review of treatment outcomes
Laryngoscope, 2014Co-Authors: Anne Hseu, Michael S. Benninger, Timothy M. Haffey, Robert R. LorenzAbstract:Objectives/Hypothesis To evaluate the endoscopic surgical management of adult Subglottic Stenosis and describe treatment outcomes. Study Design Retrospective review. Methods Ten-year review of adult patients with Subglottic Stenosis. Results Ninety-two adults (23 male, 69 female) with Subglottic Stenosis underwent 247 endoscopic dilations between 2001 and 2010. The mean age was 48 years at time of first surgery. Etiology was GPA (granulomatosis with polyangiitis, formerly Wegener's granulomatosis) (45%), intubation (25%), or idiopathic (33%). Forty-one patients (45%) underwent a single procedure; 51 patients (55%) required multiple surgeries. The average interval for patients requiring a subsequent procedure was 13.7 months. Variations in surgical technique did not show differences in time to next procedure, and the use of mitomycin-C did not result in longer intervals between procedures. No significant complications were encountered after dilation. Conclusions Subglottic Stenosis remains a treatment challenge. Although patients are often symptomatically improved after endoscopic dilation, recurrence rates remain high. Level of Evidence 4. Laryngoscope, 124:736–741, 2014
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Subglottic Stenosis: A ten‐year review of treatment outcomes
The Laryngoscope, 2013Co-Authors: Anne Hseu, Michael S. Benninger, Timothy M. Haffey, Robert R. LorenzAbstract:Objectives/Hypothesis To evaluate the endoscopic surgical management of adult Subglottic Stenosis and describe treatment outcomes. Study Design Retrospective review. Methods Ten-year review of adult patients with Subglottic Stenosis. Results Ninety-two adults (23 male, 69 female) with Subglottic Stenosis underwent 247 endoscopic dilations between 2001 and 2010. The mean age was 48 years at time of first surgery. Etiology was GPA (granulomatosis with polyangiitis, formerly Wegener's granulomatosis) (45%), intubation (25%), or idiopathic (33%). Forty-one patients (45%) underwent a single procedure; 51 patients (55%) required multiple surgeries. The average interval for patients requiring a subsequent procedure was 13.7 months. Variations in surgical technique did not show differences in time to next procedure, and the use of mitomycin-C did not result in longer intervals between procedures. No significant complications were encountered after dilation. Conclusions Subglottic Stenosis remains a treatment challenge. Although patients are often symptomatically improved after endoscopic dilation, recurrence rates remain high. Level of Evidence 4. Laryngoscope, 124:736–741, 2014
Eddy Bodart - One of the best experts on this subject based on the ideXlab platform.
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Recurrent respiratory distress and idiopathic Subglottic Stenosis: what treatment?
Archives françaises de pédiatrie, 1993Co-Authors: Eddy Bodart, De Bilderling G, Alain Mayné, Georges Lawson, Marc RemacleAbstract:Idiopathic Subglottic Stenosis is a rare cause of acute respiratory distress, that is difficult to treat (corticosteroids, tracheotomy). A nine-year-old boy presented with acute respiratory distress due to tracheal Stenosis. The symptoms recurred after the endotracheal inflammatory membranes had been removed with forceps, despite 6-months of degressive corticotherapy. Absence of other causes of tracheal Stenosis and biopsies led to diagnosis of idiopathic Subglottic Stenosis. The patient was treated by CO2 laser followed by degressive corticotherapy. The respiratory distress recurred within 3 months of discontinuing corticosteroids, requiring two further CO2 laser treatments. The patient became corticodependent. CO2 laser is an effective, wise alternative treatment of acute respiratory distress due to idiopathic Subglottic Stenosis that can be repeated if necessary.
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Treatment of Recurrent Respiratory-distress Due To Idiopathic Subglottic Stenosis
Archives françaises de pédiatrie, 1993Co-Authors: Eddy Bodart, G. Debilderling, Alain Mayné, Georges Lawson, Marc RemacleAbstract:Background. Idiopathic Subglottic Stenosis is a rare cause of acute respiratory distress, that is difficult to treat (corticosteroids, tracheotomy). Case report. A nine-year-old boy presented with acute respiratory distress due to tracheal Stenosis. The symptoms recurred after the endotracheal inflammatory membranes had been removed with forceps, despite 6-months of degressive corticotherapy. Absence of other causes of tracheal Stenosis and biopsies led to diagnosis of idiopathic Subglottic Stenosis. The patient was treated by CO2 laser followed by degressive corticotherapy. The respiratory distress recurred within 3 months of discontinuing corticosteroids, requiring two further CO2 laser treatments. The patient became corticodependent. Conclusions. CO2 laser is an effective, wise alternative treatment of acute respiratory distress due to idiopathic Subglottic Stenosis that can be repeated if necessary.
Matthew R Naunheim - One of the best experts on this subject based on the ideXlab platform.
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patient preferences in Subglottic Stenosis treatment a discrete choice experiment
Otolaryngology-Head and Neck Surgery, 2018Co-Authors: Mark G Shrime, Ramon A Franco, Vinay K Rathi, Matthew R Naunheim, Phillip C SongAbstract:: Objectives Subglottic Stenosis can be addressed with several different surgical techniques, but patient preferences for these treatment modalities are poorly understood. Economic methods are increasingly being used to understand how patients make decisions. The objective of this pilot study was to assess preferences in Subglottic Stenosis treatment using patient-centric stated preference techniques. Study Design Discrete choice experiment (DCE). Setting Academic research facility. Subjects and Methods A computer-based DCE was administered in a monitored setting to volunteers from the general population. Signs and symptoms of Subglottic Stenosis were described, and participants were asked to imagine they had Subglottic Stenosis. Hypothetical treatments were offered, with 5 systematically varied attributes: need for external incision, length of hospital stay, postoperative voice quality, likelihood of repeat procedures, and risk of complication. A conditional logistic model was used to assess the relative attribute importance. Results In total, 162 participants were included. Attributes with the greatest impact on decision making included potential need for repeat procedures (importance 30.2%; P < .001), amount of operative risk (importance 28.1%; P < .001), and postoperative voice quality (importance 27.7%; P < .001), whereas presence of incision (importance 5.0%; P = .001) was less important, and hospital stay was not (importance 9.0%; P = .089). Based on aggregate responses for these attributes, the model demonstrated that most participants (80.4%) would prefer endoscopic surgery for Subglottic Stenosis as opposed to open tracheal resection (19.6%). Conclusion In this pilot population, most participants preferred voice-sparing, low-risk procedures as treatment for Subglottic Stenosis, consistent with an endoscopic approach, even if multiple procedures were required.
Anne Hseu - One of the best experts on this subject based on the ideXlab platform.
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Subglottic Stenosis a ten year review of treatment outcomes
Laryngoscope, 2014Co-Authors: Anne Hseu, Michael S. Benninger, Timothy M. Haffey, Robert R. LorenzAbstract:Objectives/Hypothesis To evaluate the endoscopic surgical management of adult Subglottic Stenosis and describe treatment outcomes. Study Design Retrospective review. Methods Ten-year review of adult patients with Subglottic Stenosis. Results Ninety-two adults (23 male, 69 female) with Subglottic Stenosis underwent 247 endoscopic dilations between 2001 and 2010. The mean age was 48 years at time of first surgery. Etiology was GPA (granulomatosis with polyangiitis, formerly Wegener's granulomatosis) (45%), intubation (25%), or idiopathic (33%). Forty-one patients (45%) underwent a single procedure; 51 patients (55%) required multiple surgeries. The average interval for patients requiring a subsequent procedure was 13.7 months. Variations in surgical technique did not show differences in time to next procedure, and the use of mitomycin-C did not result in longer intervals between procedures. No significant complications were encountered after dilation. Conclusions Subglottic Stenosis remains a treatment challenge. Although patients are often symptomatically improved after endoscopic dilation, recurrence rates remain high. Level of Evidence 4. Laryngoscope, 124:736–741, 2014
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Subglottic Stenosis: A ten‐year review of treatment outcomes
The Laryngoscope, 2013Co-Authors: Anne Hseu, Michael S. Benninger, Timothy M. Haffey, Robert R. LorenzAbstract:Objectives/Hypothesis To evaluate the endoscopic surgical management of adult Subglottic Stenosis and describe treatment outcomes. Study Design Retrospective review. Methods Ten-year review of adult patients with Subglottic Stenosis. Results Ninety-two adults (23 male, 69 female) with Subglottic Stenosis underwent 247 endoscopic dilations between 2001 and 2010. The mean age was 48 years at time of first surgery. Etiology was GPA (granulomatosis with polyangiitis, formerly Wegener's granulomatosis) (45%), intubation (25%), or idiopathic (33%). Forty-one patients (45%) underwent a single procedure; 51 patients (55%) required multiple surgeries. The average interval for patients requiring a subsequent procedure was 13.7 months. Variations in surgical technique did not show differences in time to next procedure, and the use of mitomycin-C did not result in longer intervals between procedures. No significant complications were encountered after dilation. Conclusions Subglottic Stenosis remains a treatment challenge. Although patients are often symptomatically improved after endoscopic dilation, recurrence rates remain high. Level of Evidence 4. Laryngoscope, 124:736–741, 2014
