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Robin T Cotton - One of the best experts on this subject based on the ideXlab platform.
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chronic aspiration in children when are bilateral Submandibular Gland excision and parotid duct ligation indicated
Archives of Otolaryngology-head & Neck Surgery, 1996Co-Authors: Mark E Gerber, Michael D Gaugler, Charles M Myer, Robin T CottonAbstract:Objective: To assess the efficacy of bilateral Submandibular Gland excision and bilateral parotid duct ligation in treatment of chronic aspiration in neurologically impaired children. Design: Retrospective chart review and telephone follow-up interview. Setting: Tertiary care center. Patients: All patients from 1986 through 1994 who underwent bilateral Submandibular Gland excision and bilateral parotid duct ligation and had evidence of at least 1 episode of aspiration pneumonia in the year prior to undergoing surgery. Main Outcome Measure: Two main outcomes measures were (1) the change in number of hospitalizations for pneumonia and total number of lower respiratory tract infections between 1 year before and 1 year after surgical intervention and (2) telephone assessment of patient outcome with respect to parental satisfaction, effect on quality of life, care requirements, amount of suctioning, and use of voice. Results: Sixteen patients aged 16 months to 18 years were included. After surgical intervention, there was a significant decrease in the mean (±SD) number of pneumonias (2.3±1.44 before surgery, 0.9±1.2 after surgery; P Conclusion: Bilateral Submandibular Gland excision and bilateral parotid duct ligation reduce the incidence of aspiration pneumonias and hospitalization, and decrease overall care requirements in a select group of neurologically impaired children. Because they are voice sparing, are efficacious, and have a low morbidity, they should be considered before laryngotracheal separation or tracheoesophageal diversion. Arch Otolaryngol Head Neck Surg. 1996;122:1368-1371
Yoshiaki Imamura - One of the best experts on this subject based on the ideXlab platform.
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sarcomatoid salivary duct carcinoma of the Submandibular Gland a case report
Acta Cytologica, 2010Co-Authors: Masaki Mori, Makoto Ohta, Hideki Maegawa, Toshie Hara, Yoshiaki ImamuraAbstract:Background Sarcomatoid salivary duct carcinoma (sarcomatoid SDC) is a rare subtype of SDC. We encountered 1 case of sarcomatoid SDC that developed from a Submandibular Gland pleomorphic adenoma, and we herein report our findings. Case A 42-year-old female had tumentia and pain in the right submental area, and therefore she underwent a close examination, wherein a right Submandibular Gland neoplasm was detected. Surgery for removing the right Submandibular Gland was performed in addition to neck dissection. Cytology showed typical findings of conventional SDC. Moreover, isolated and scattered large spindle cells and multinucleated cells were also detected along with atypical epidermal cell clumps showing keratinization. From a histologic perspective, it appeared to be sarcomatoid SDC that developed from a pleomorphic adenoma and also involved a squamous cell carcinoma component. Conclusion This is the first report on the cytologic findings of a case of sarcomatoid SDC with a squamous cell carcinoma component. When sarcomatoid cells appear in the cytology along with findings of typical SDC, sarcomatoid SDC should thus be considered. Furthermore, squamous cell carcinoma component may be involved as in the present case, so it is necessary to be aware of the possibility thereof.
Yu Guang-yan - One of the best experts on this subject based on the ideXlab platform.
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Prevention of radiation-induced xerostomia by Submandibular Gland transfer
head and neck journal for the sciences and specialties of the head and neck, 2012Co-Authors: Ye Zhang, Guo Chuan-bin, Zhang Lei, Wang Yang, Peng Xin, Mao Chi, Yu Guang-yanAbstract:Background This study was carried out for the purpose of evaluating the efficacy of Submandibular Gland transfer to prevent radiation-induced xerostomia. Methods Thirty-eight patients with oropharyngeal carcinoma were recruited. Twenty-six Submandibular Glands were transferred into the submental space to elude radiotherapy in 24 patients (transfer group); the Submandibular Gland was not disturbed in the control group (n = 14). The salivary flow rate, xerostomia, and quality of life (QOL) were assessed preoperatively, postoperatively, and after radiotherapy. The swallowing function was then evaluated after radiotherapy. Results All the transferred Glands survived and functioned after radiotherapy. The Submandibular salivary flow rate recovered by 6 months after radiotherapy in the transfer group, whereas the flow rate declined drastically after radiotherapy and remained at a low level in the longer term in the control group. Two years after radiotherapy, 92.3% of patients in the transfer group had no or minimal xerostomia. QOL in the transfer group was better than that in the control group from 3 months after radiotherapy. Histologically, the majority of the transferred Glands had normal Glandular acini and ducts. There was no significant difference in dysphagia between the groups. Conclusions The Submandibular Gland can be successfully transferred to the submental space, thus preserving salivary function and preventing radiation-induced xerostomia. The transfer of the Submandibular Gland can improve the QOL by alleviating xerostomia, although it did not relieve dysphagia in this study. (c) 2011 Wiley Periodicals, Inc. Head Neck, 2011http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000305513100004&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=8e1609b174ce4e31116a60747a720701OtorhinolaryngologySurgerySCI(E)PubMed9ARTICLE7937-9423
Mark E Gerber - One of the best experts on this subject based on the ideXlab platform.
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chronic aspiration in children when are bilateral Submandibular Gland excision and parotid duct ligation indicated
Archives of Otolaryngology-head & Neck Surgery, 1996Co-Authors: Mark E Gerber, Michael D Gaugler, Charles M Myer, Robin T CottonAbstract:Objective: To assess the efficacy of bilateral Submandibular Gland excision and bilateral parotid duct ligation in treatment of chronic aspiration in neurologically impaired children. Design: Retrospective chart review and telephone follow-up interview. Setting: Tertiary care center. Patients: All patients from 1986 through 1994 who underwent bilateral Submandibular Gland excision and bilateral parotid duct ligation and had evidence of at least 1 episode of aspiration pneumonia in the year prior to undergoing surgery. Main Outcome Measure: Two main outcomes measures were (1) the change in number of hospitalizations for pneumonia and total number of lower respiratory tract infections between 1 year before and 1 year after surgical intervention and (2) telephone assessment of patient outcome with respect to parental satisfaction, effect on quality of life, care requirements, amount of suctioning, and use of voice. Results: Sixteen patients aged 16 months to 18 years were included. After surgical intervention, there was a significant decrease in the mean (±SD) number of pneumonias (2.3±1.44 before surgery, 0.9±1.2 after surgery; P Conclusion: Bilateral Submandibular Gland excision and bilateral parotid duct ligation reduce the incidence of aspiration pneumonias and hospitalization, and decrease overall care requirements in a select group of neurologically impaired children. Because they are voice sparing, are efficacious, and have a low morbidity, they should be considered before laryngotracheal separation or tracheoesophageal diversion. Arch Otolaryngol Head Neck Surg. 1996;122:1368-1371
Derald Oldring - One of the best experts on this subject based on the ideXlab platform.
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Submandibular Gland transfer a new method of preventing radiation induced xerostomia
Laryngoscope, 2001Co-Authors: Hadi Seikaly, Timothy Mcgaw, Linda Coulter, Derald OldringAbstract:Objective Radiation-induced xerostomia is a significant morbidity of radiation therapy in the management of patients with head and neck cancers. We have recently reported a method of transfer of one Submandibular Gland to the submental space in a small pilot series of eligible surgical patients. The submental space was shielded during postoperative radiation therapy. The transferred Gland continued to function after the completion of radiation therapy and none of the patients developed xerostomia. The purpose of this article is to present the technique of Submandibular Gland transfer in detail and to evaluate the postoperative survival and function of the transferred Submandibular Glands. Design Prospective clinical trial. Methods The Submandibular Gland was transferred on eligible patients as part of their surgical intervention. The patients were followed clinically, with salivary flow and radioisotope studies. Results We performed the surgical transfer of the Submandibular salivary Gland in 24 of 25 patients placed on the protocol. All the Glands survived transfer and functioned well postoperatively as demonstrated on the salivary flow and the radioisotope studies. The surgical transfer was relatively simple and added 45 minutes to the surgical procedure. There were no complications attributed to the Submandibular Gland transfer. Conclusions We have successfully demonstrated that the Submandibular Gland can be surgically transferred to the submental space with its function preserved. The Gland seems to continue functioning even after radiation therapy with the appropriate shielding. This surgical transfer procedure has the potential to change the way we currently manage patients with head and neck cancer.
