The Experts below are selected from a list of 2628 Experts worldwide ranked by ideXlab platform
Carsten Bocker Pedersen - One of the best experts on this subject based on the ideXlab platform.
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full spectrum of psychiatric outcomes among offspring with parental history of mental disorder
Archives of General Psychiatry, 2010Co-Authors: Kimberlie Dean, Hanne Stevens, Preben Bo Mortensen, Robin M. Murray, Elizabeth Walsh, Carsten Bocker PedersenAbstract:Context While concordant parent/offspring risks for specific mental Disorders are well established, knowledge of the broader range of psychiatric outcomes among offspring with parental history of mental disorder is lacking. Objective To examine the full range of mental health outcomes among offspring of parents with serious and other mental Disorders compared with those whose parents had no such history. Design Population-based cohort study. Offspring were followed up from their 14th birthday for the development of mental Disorders based on both outpatient and inpatient hospital data. Setting Danish population. Participants All offspring born in Denmark between 1980 and 1994 (N = 865 078) with follow-up to December 2008. Main Outcome Measures Incidence rates, incidence rate ratios, and cumulative incidences for offspring psychiatric outcomes. Results Parental serious mental disorder (SMD) (nonaffective or affective psychosis) was found to be positively associated with virtually all offspring psychiatric outcomes, including those not hitherto regarded as clinically related. Offspring of parents without SMD but with a history of “other mental disorder” were also found to be at increased risk of developing a range of mental Disorders. The strongest associations were found where both parents had a history of mental disorder (eg, offspring of 2 parents with SMD were 13 times more likely to develop schizophrenia). Elevated risks were not confined to concordant parent/offspring Disorders (eg, offspring of 2 parents with SMD were 8 times more likely to develop Substance Misuse Disorders). Conclusions The impact of parental history of mental disorder was not confined to elevated offspring risk of concordant Disorders but rather offspring are at increased risk of a wide range of mental Disorders, particularly those with 2 affected parents. Our results imply an important role for etiological factors giving rise to broad, as well as specific, familial vulnerabilities. These findings also have potential implications for diagnostic classification.
Carsten B Pedersen - One of the best experts on this subject based on the ideXlab platform.
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full spectrum of mental Disorders linked with childhood residential mobility
Journal of Psychiatric Research, 2016Co-Authors: Pearl L H Mok, Roger T Webb, Louis Appleby, Carsten B PedersenAbstract:Although links between childhood residential mobility and subsequently increased risks of psychopathology have been well documented, associations across the full spectrum of psychiatric Disorders are unknown. We conducted a population-based study of all 1,439,363 persons born in Denmark during 1971–1997 to investigate relationships between childhood cross-municipality residential moves from year of birth to age 14 years and the development of a range of psychiatric Disorders from mid-adolescence to early middle age. We examined: (1) Any Substance Misuse Disorders; specifically alcohol Misuse, and cannabis Misuse; (2) Any personality Disorders; specifically antisocial, and borderline personality Disorders; (3) Schizophrenia and related Disorders; specifically schizophrenia, and schizoaffective disorder; (4) Any mood Disorders; specifically bipolar disorder, and depressive disorder; (5) Any anxiety and somatoform Disorders; specifically obsessive compulsive disorder; (6) Any eating Disorders; specifically anorexia nervosa. Childhood residential mobility was associated with elevated risks of developing most psychiatric Disorders, even after controlling for potential confounders. The associations generally rose with increasing age at moving and were stronger for multiple moves in a year compared to a single move. Links were particularly strong for antisocial personality disorder, any Substance Misuse disorder, and cannabis Misuse in particular, for which the highest increases in risks were observed if relocation occurred during adolescence. Childhood residential change was not linked to subsequent risk of developing an eating disorder. Frequent residential mobility could be a marker for familial adversities. Mental health services and schools need to be vigilant of the psychosocial needs of children, particularly adolescents, who have recently moved homes.
Morris Weinberger - One of the best experts on this subject based on the ideXlab platform.
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can shelter based interventions improve treatment engagement in homeless individuals with psychiatric and or Substance Misuse Disorders a randomized controlled trial
Medical Care, 2005Co-Authors: Daniel W Bradford, Bradley N Gaynes, Mimi M Kim, Jay S Kaufman, Morris WeinbergerAbstract:Background: High proportions of homeless individuals have mental illness and Substance use Disorders. Few of these individuals engage in consistent treatment, although they are likely to benefit from it. Shelter-based interventions to help this population engage in treatment have not been studied in a rigorous manner. Objectives: We sought to evaluate the effectiveness of a shelter-based intervention, including intensive outreach by a psychiatric social worker and availability of weekly psychiatrist visits with continuity of care to engage homeless individuals with psychiatric and Substance use problems. Research Design: This was a randomized controlled trial. Subjects: A total of 102 individuals were referred to a shelter-based psychiatric clinic. Measures: The primary outcome measure was first appointment attendance at a community mental health center (CMHC). Secondary outcome measures were attendance at second and third CMHC appointments, participation in a Substance abuse program, and employment and housing status at shelter exit. Results: Individuals receiving the intervention were more likely to attend ≥1 CMHC appointment (64.7% versus 37.3%, P = 0.006) and to participate in a Substance abuse program (51.4% versus 12.5%, P = 0.0006) than those in the control group. There was a trend towards being more likely to attend 2 CMHC visits (33.3% versus 17.7%, P = 0.083), but no significant differences in attending 3 visits, being employed, or having housing. Conclusions: Shelter-based interventions hold promise for improving treatment engagement in homeless populations with psychiatric and Substance use problems. Further study should address how to foster care beyond an initial CMHC appointment and clarify key program components using a wider range of outcome measures.
Stuart A Kinner - One of the best experts on this subject based on the ideXlab platform.
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prevalence of mental illness among aboriginal and torres strait islander people in queensland prisons
The Medical Journal of Australia, 2012Co-Authors: Ed Heffernan, Kimina Andersen, Abhilash Dev, Stuart A KinnerAbstract:OBJECTIVE: To estimate the prevalence of mental disorder in a representative sample of Aboriginal and Torres Strait Islander people in Queensland prisons. DESIGN, SETTING AND PARTICIPANTS: Cross-sectional assessment of mental health using the Composite International Diagnostic Interview (CIDI) and clinical interviews, conducted by Indigenous mental health clinicians who undertook specific training for this purpose, with support from forensic psychiatrists when indicated. We assessed adults who self-identified as Indigenous and were incarcerated in six of the nine major correctional centres across Queensland (housing 75% of all Indigenous men and 90% of all Indigenous women in Queensland prisons) between May and June 2008. MAIN OUTCOME MEASURES: Diagnoses of anxiety, depressive and Substance Misuse Disorders using the CIDI; diagnosis of psychotic illness determined through psychiatrist interviews supplemented by a diagnostic panel. RESULTS: We interviewed 25% of all Indigenous men (347/1381; mean age, 31.5 years) and 62% of all Indigenous women (72/116; mean age, 29.2 years) incarcerated at the time of our study. The recruitment fraction was 71% for men and 81% for women. Among the 396 individuals who completed both the interview and the CIDI, the 12-month prevalence of mental disorder was 73% among men and 86% among women. This comprised anxiety Disorders (men, 20%; women, 51%); depressive Disorders (men, 11%; women, 29%); psychotic Disorders (men, 8%; women, 23%) and Substance Misuse Disorders (men, 66%; women, 69%). CONCLUSIONS: The prevalence of mental disorder among Indigenous adults in Queensland custody is very high compared with community estimates. There remains an urgent need to develop and resource culturally capable mental health services for Indigenous Australians in custody.
Kimberlie Dean - One of the best experts on this subject based on the ideXlab platform.
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full spectrum of psychiatric outcomes among offspring with parental history of mental disorder
Archives of General Psychiatry, 2010Co-Authors: Kimberlie Dean, Hanne Stevens, Preben Bo Mortensen, Robin M. Murray, Elizabeth Walsh, Carsten Bocker PedersenAbstract:Context While concordant parent/offspring risks for specific mental Disorders are well established, knowledge of the broader range of psychiatric outcomes among offspring with parental history of mental disorder is lacking. Objective To examine the full range of mental health outcomes among offspring of parents with serious and other mental Disorders compared with those whose parents had no such history. Design Population-based cohort study. Offspring were followed up from their 14th birthday for the development of mental Disorders based on both outpatient and inpatient hospital data. Setting Danish population. Participants All offspring born in Denmark between 1980 and 1994 (N = 865 078) with follow-up to December 2008. Main Outcome Measures Incidence rates, incidence rate ratios, and cumulative incidences for offspring psychiatric outcomes. Results Parental serious mental disorder (SMD) (nonaffective or affective psychosis) was found to be positively associated with virtually all offspring psychiatric outcomes, including those not hitherto regarded as clinically related. Offspring of parents without SMD but with a history of “other mental disorder” were also found to be at increased risk of developing a range of mental Disorders. The strongest associations were found where both parents had a history of mental disorder (eg, offspring of 2 parents with SMD were 13 times more likely to develop schizophrenia). Elevated risks were not confined to concordant parent/offspring Disorders (eg, offspring of 2 parents with SMD were 8 times more likely to develop Substance Misuse Disorders). Conclusions The impact of parental history of mental disorder was not confined to elevated offspring risk of concordant Disorders but rather offspring are at increased risk of a wide range of mental Disorders, particularly those with 2 affected parents. Our results imply an important role for etiological factors giving rise to broad, as well as specific, familial vulnerabilities. These findings also have potential implications for diagnostic classification.
