The Experts below are selected from a list of 7002 Experts worldwide ranked by ideXlab platform
Stephen T. Hilton - One of the best experts on this subject based on the ideXlab platform.
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3d printed polypropylene continuous flow column reactors exploration of reactor utility in snar reactions and the synthesis of bicyclic and tetracyclic heterocycles
European Journal of Organic Chemistry, 2017Co-Authors: Bhaven Patel, Alessandra Monaco, Enora Pichon, Mark Ladlow, Marta Barniolxicota, Stephen T. HiltonAbstract:3D printing has the potential to transform the way in which chemical reactions are carried out due to its low-cost, ease-of-use as a technology and its capacity to expedite the development of iteratively enhanced prototypes. In this present study, we developed a novel, low-cost polypropylene (PP) column reactor that was incorporated into an existing continuous-flow reactor for the synthesis of heterocycles. The utility and solvent resistance of the printed devices were explored in SNAr reactions to produce Substituted Aniline derivatives and in the synthesis of bicyclic and tetracyclic heterocycles. Using this approach, a range of heterocyclic compounds was synthesised including the core structure of the natural product (±)-γ-lycorane and structurally complex compounds based on the tetracyclic core of the erythrina alkaloids.
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3D‐Printed Polypropylene Continuous‐Flow Column Reactors: Exploration of Reactor Utility in SNAr Reactions and the Synthesis of Bicyclic and Tetracyclic Heterocycles
European Journal of Organic Chemistry, 2017Co-Authors: Bhaven Patel, Alessandra Monaco, Marta Barniol-xicota, Enora Pichon, Mark Ladlow, Stephen T. HiltonAbstract:3D printing has the potential to transform the way in which chemical reactions are carried out due to its low-cost, ease-of-use as a technology and its capacity to expedite the development of iteratively enhanced prototypes. In this present study, we developed a novel, low-cost polypropylene (PP) column reactor that was incorporated into an existing continuous-flow reactor for the synthesis of heterocycles. The utility and solvent resistance of the printed devices were explored in SNAr reactions to produce Substituted Aniline derivatives and in the synthesis of bicyclic and tetracyclic heterocycles. Using this approach, a range of heterocyclic compounds was synthesised including the core structure of the natural product (±)-γ-lycorane and structurally complex compounds based on the tetracyclic core of the erythrina alkaloids.
Corrie T Imrie - One of the best experts on this subject based on the ideXlab platform.
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synthesis thermal and optical behaviour of non symmetric liquid crystal dimers α 4 benzylidene Substituted Aniline 4 oxy ω pentyl 4 4 phenyl benzoateoxy hexane
Phase Transitions, 2011Co-Authors: Guanyeow Yeap, Hueycharn Lee, Wan Ahmad Kamil Mahmood, Corrie T Imrie, Daisuke Takeuchi, Kohtaro OsakadaAbstract:A series of six non-symmetric liquid crystal dimers α-(4-benzylidene-Substituted-Aniline-4′-oxy)-ω-[pentyl-4-(4′-phenyl)benzoateoxy]hexane have been synthesized and characterized. These dimers vary from one another in terms of the terminal substituent (H, CH3, C2H5, F, Cl and Br) with different polarizabilities and molecular sizes. Investigation on the thermal behaviour shows that the dimer with a more polarizable terminal substituent of Br atom exhibits a smectic A phase as well as an enantiotropic nematic phase. Influence of the molecular size of the terminal substituent in stabilizing the liquid crystalline properties is also studied.
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why do non symmetric dimers intercalate the synthesis and characterisation of the α 4 benzylidene Substituted Aniline 4 oxy ω 2 methylbutyl 4 4 phenyl benzoateoxy alkanes
Liquid Crystals, 2009Co-Authors: Guanyeow Yeap, Wan Ahmad Kamil Mahmood, Tiangchuan Hng, Sueyi Yeap, Ewa Gorecka, Masato M Ito, Koichi Ueno, Masaki Okamoto, Corrie T ImrieAbstract:Ten new non-symmetric liquid crystal dimers belonging to the family of compounds α-(4-benzylidene-Substituted-Aniline-4′-oxy)-ω-(2-methylbutyl-4′-(4″-phenyl)benzoateoxy)-alkanes have been synthesised and their transitional properties characterised. The dimers contain either a hexamethylene or octamethylene spacer, while the terminal substituents on the 4-benzylideneAniline fragment are H, CH3, F, Cl and Br. The unSubstituted dimers are not liquid crystalline, while the remaining compounds exhibit enantiotropic nematic behaviour. The trends in the clearing temperatures, according to the chemical nature of the terminal substituent, are largely consistent with those established for conventional low molar mass liquid crystals. Three of the dimers also exhibit an intercalated smectic A phase, specifically the two bromo-Substituted dimers and the chloro-Substituted dimer containing a hexamethylene spacer. The driving force for the formation of this phase is considered to be, at least in part, the specific aniso...
Bhaven Patel - One of the best experts on this subject based on the ideXlab platform.
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3d printed polypropylene continuous flow column reactors exploration of reactor utility in snar reactions and the synthesis of bicyclic and tetracyclic heterocycles
European Journal of Organic Chemistry, 2017Co-Authors: Bhaven Patel, Alessandra Monaco, Enora Pichon, Mark Ladlow, Marta Barniolxicota, Stephen T. HiltonAbstract:3D printing has the potential to transform the way in which chemical reactions are carried out due to its low-cost, ease-of-use as a technology and its capacity to expedite the development of iteratively enhanced prototypes. In this present study, we developed a novel, low-cost polypropylene (PP) column reactor that was incorporated into an existing continuous-flow reactor for the synthesis of heterocycles. The utility and solvent resistance of the printed devices were explored in SNAr reactions to produce Substituted Aniline derivatives and in the synthesis of bicyclic and tetracyclic heterocycles. Using this approach, a range of heterocyclic compounds was synthesised including the core structure of the natural product (±)-γ-lycorane and structurally complex compounds based on the tetracyclic core of the erythrina alkaloids.
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3D‐Printed Polypropylene Continuous‐Flow Column Reactors: Exploration of Reactor Utility in SNAr Reactions and the Synthesis of Bicyclic and Tetracyclic Heterocycles
European Journal of Organic Chemistry, 2017Co-Authors: Bhaven Patel, Alessandra Monaco, Marta Barniol-xicota, Enora Pichon, Mark Ladlow, Stephen T. HiltonAbstract:3D printing has the potential to transform the way in which chemical reactions are carried out due to its low-cost, ease-of-use as a technology and its capacity to expedite the development of iteratively enhanced prototypes. In this present study, we developed a novel, low-cost polypropylene (PP) column reactor that was incorporated into an existing continuous-flow reactor for the synthesis of heterocycles. The utility and solvent resistance of the printed devices were explored in SNAr reactions to produce Substituted Aniline derivatives and in the synthesis of bicyclic and tetracyclic heterocycles. Using this approach, a range of heterocyclic compounds was synthesised including the core structure of the natural product (±)-γ-lycorane and structurally complex compounds based on the tetracyclic core of the erythrina alkaloids.
Guanyeow Yeap - One of the best experts on this subject based on the ideXlab platform.
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synthesis thermal and optical behaviour of non symmetric liquid crystal dimers α 4 benzylidene Substituted Aniline 4 oxy ω pentyl 4 4 phenyl benzoateoxy hexane
Phase Transitions, 2011Co-Authors: Guanyeow Yeap, Hueycharn Lee, Wan Ahmad Kamil Mahmood, Corrie T Imrie, Daisuke Takeuchi, Kohtaro OsakadaAbstract:A series of six non-symmetric liquid crystal dimers α-(4-benzylidene-Substituted-Aniline-4′-oxy)-ω-[pentyl-4-(4′-phenyl)benzoateoxy]hexane have been synthesized and characterized. These dimers vary from one another in terms of the terminal substituent (H, CH3, C2H5, F, Cl and Br) with different polarizabilities and molecular sizes. Investigation on the thermal behaviour shows that the dimer with a more polarizable terminal substituent of Br atom exhibits a smectic A phase as well as an enantiotropic nematic phase. Influence of the molecular size of the terminal substituent in stabilizing the liquid crystalline properties is also studied.
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why do non symmetric dimers intercalate the synthesis and characterisation of the α 4 benzylidene Substituted Aniline 4 oxy ω 2 methylbutyl 4 4 phenyl benzoateoxy alkanes
Liquid Crystals, 2009Co-Authors: Guanyeow Yeap, Wan Ahmad Kamil Mahmood, Tiangchuan Hng, Sueyi Yeap, Ewa Gorecka, Masato M Ito, Koichi Ueno, Masaki Okamoto, Corrie T ImrieAbstract:Ten new non-symmetric liquid crystal dimers belonging to the family of compounds α-(4-benzylidene-Substituted-Aniline-4′-oxy)-ω-(2-methylbutyl-4′-(4″-phenyl)benzoateoxy)-alkanes have been synthesised and their transitional properties characterised. The dimers contain either a hexamethylene or octamethylene spacer, while the terminal substituents on the 4-benzylideneAniline fragment are H, CH3, F, Cl and Br. The unSubstituted dimers are not liquid crystalline, while the remaining compounds exhibit enantiotropic nematic behaviour. The trends in the clearing temperatures, according to the chemical nature of the terminal substituent, are largely consistent with those established for conventional low molar mass liquid crystals. Three of the dimers also exhibit an intercalated smectic A phase, specifically the two bromo-Substituted dimers and the chloro-Substituted dimer containing a hexamethylene spacer. The driving force for the formation of this phase is considered to be, at least in part, the specific aniso...
Gabor Merenyi - One of the best experts on this subject based on the ideXlab platform.
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REDOX AND ACIDITY PROPERTIES OF 4-Substituted Aniline RADICAL CATIONS IN WATER
Journal of the American Chemical Society, 1994Co-Authors: Mats Jonsson, Johan Lind, Trygve E. Eriksen, Gabor MerenyiAbstract:By means of pulse radiolysis the one-electron reduction potentials of twelve 4-Substituted Aniline radical cations and the pK a values of eight 4-Substituted Aniline radical cations have been determined. Both the potentials and the pK a values were shown to be linearly dependent on the Brown σ p + values for the 4-substituents. The one-electron reduction potentials were also compared to previously reported electrochemically determined E 1/2 values resulting in good agreement between the two sets of data. By combining the one-electron reduction potentials and the pK a values the N-H bond dissociation energies of some 4-Substituted Anilines were calculated, also showing a linear substituent dependence
