The Experts below are selected from a list of 315 Experts worldwide ranked by ideXlab platform
Masakatsu Asami - One of the best experts on this subject based on the ideXlab platform.
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phenolic resins 100 years of progress and their future
Reactive & Functional Polymers, 2013Co-Authors: Kazuhisa Hirano, Masakatsu AsamiAbstract:Abstract Phenolic resins have been under continuous development as an important thermosetting resin material since the first Successful Trial production of the synthetic resin in Japan in 1911. Sumitomo Bakelite Co., Ltd. traces its origin to the birth of this material (i.e. the Successful Trial production) and has been developing synthetic and composite production technologies since that time for adaptation to various applications. Phenolic resin molding compounds, which have been among the major applications of phenolic resins since their inception, exhibit highly favorable characteristics in terms of strength, heat-resistance, long-term reliability and cost, and therefore have been used in a wide range of applications from kitchen parts to components for electronic appliances and automobiles. In particular, phenolic resin molding compounds are gathering attention as a lightweight solution to replace metals in automotive applications, among others applications, and we are investigating these applications while making a vigorous research effort toward further improving the mechanical properties of these materials. This new research and development is founded on detailed prediction and analysis of the hardened structures in phenolic resins. This report outlines the history of phenolic resins, which were invented in 1907 and brought to Japan, along with the associated technology, as a result of personal ties between Dr. Leo Hendrik Baekeland and Dr. Jokichi Takamine; the widening application of phenolic resins in recent years; showcase applications based on green sustainable chemistry; and examples of new analysis methods (chemical analysis) and structural analysis. We hope this report will encourage the research and development of plastics in the new century and the development of commercial products [1] .
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Phenolic resins—100 years of progress and their future
Reactive & Functional Polymers, 2013Co-Authors: Kazuhisa Hirano, Masakatsu AsamiAbstract:Abstract Phenolic resins have been under continuous development as an important thermosetting resin material since the first Successful Trial production of the synthetic resin in Japan in 1911. Sumitomo Bakelite Co., Ltd. traces its origin to the birth of this material (i.e. the Successful Trial production) and has been developing synthetic and composite production technologies since that time for adaptation to various applications. Phenolic resin molding compounds, which have been among the major applications of phenolic resins since their inception, exhibit highly favorable characteristics in terms of strength, heat-resistance, long-term reliability and cost, and therefore have been used in a wide range of applications from kitchen parts to components for electronic appliances and automobiles. In particular, phenolic resin molding compounds are gathering attention as a lightweight solution to replace metals in automotive applications, among others applications, and we are investigating these applications while making a vigorous research effort toward further improving the mechanical properties of these materials. This new research and development is founded on detailed prediction and analysis of the hardened structures in phenolic resins. This report outlines the history of phenolic resins, which were invented in 1907 and brought to Japan, along with the associated technology, as a result of personal ties between Dr. Leo Hendrik Baekeland and Dr. Jokichi Takamine; the widening application of phenolic resins in recent years; showcase applications based on green sustainable chemistry; and examples of new analysis methods (chemical analysis) and structural analysis. We hope this report will encourage the research and development of plastics in the new century and the development of commercial products [1] .
Kazuhisa Hirano - One of the best experts on this subject based on the ideXlab platform.
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phenolic resins 100 years of progress and their future
Reactive & Functional Polymers, 2013Co-Authors: Kazuhisa Hirano, Masakatsu AsamiAbstract:Abstract Phenolic resins have been under continuous development as an important thermosetting resin material since the first Successful Trial production of the synthetic resin in Japan in 1911. Sumitomo Bakelite Co., Ltd. traces its origin to the birth of this material (i.e. the Successful Trial production) and has been developing synthetic and composite production technologies since that time for adaptation to various applications. Phenolic resin molding compounds, which have been among the major applications of phenolic resins since their inception, exhibit highly favorable characteristics in terms of strength, heat-resistance, long-term reliability and cost, and therefore have been used in a wide range of applications from kitchen parts to components for electronic appliances and automobiles. In particular, phenolic resin molding compounds are gathering attention as a lightweight solution to replace metals in automotive applications, among others applications, and we are investigating these applications while making a vigorous research effort toward further improving the mechanical properties of these materials. This new research and development is founded on detailed prediction and analysis of the hardened structures in phenolic resins. This report outlines the history of phenolic resins, which were invented in 1907 and brought to Japan, along with the associated technology, as a result of personal ties between Dr. Leo Hendrik Baekeland and Dr. Jokichi Takamine; the widening application of phenolic resins in recent years; showcase applications based on green sustainable chemistry; and examples of new analysis methods (chemical analysis) and structural analysis. We hope this report will encourage the research and development of plastics in the new century and the development of commercial products [1] .
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Phenolic resins—100 years of progress and their future
Reactive & Functional Polymers, 2013Co-Authors: Kazuhisa Hirano, Masakatsu AsamiAbstract:Abstract Phenolic resins have been under continuous development as an important thermosetting resin material since the first Successful Trial production of the synthetic resin in Japan in 1911. Sumitomo Bakelite Co., Ltd. traces its origin to the birth of this material (i.e. the Successful Trial production) and has been developing synthetic and composite production technologies since that time for adaptation to various applications. Phenolic resin molding compounds, which have been among the major applications of phenolic resins since their inception, exhibit highly favorable characteristics in terms of strength, heat-resistance, long-term reliability and cost, and therefore have been used in a wide range of applications from kitchen parts to components for electronic appliances and automobiles. In particular, phenolic resin molding compounds are gathering attention as a lightweight solution to replace metals in automotive applications, among others applications, and we are investigating these applications while making a vigorous research effort toward further improving the mechanical properties of these materials. This new research and development is founded on detailed prediction and analysis of the hardened structures in phenolic resins. This report outlines the history of phenolic resins, which were invented in 1907 and brought to Japan, along with the associated technology, as a result of personal ties between Dr. Leo Hendrik Baekeland and Dr. Jokichi Takamine; the widening application of phenolic resins in recent years; showcase applications based on green sustainable chemistry; and examples of new analysis methods (chemical analysis) and structural analysis. We hope this report will encourage the research and development of plastics in the new century and the development of commercial products [1] .
Ronald F. Van Vollenhoven - One of the best experts on this subject based on the ideXlab platform.
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Complex disease=complex Trial? Lessons from a Successful Trial of anti-IFNα in SLE.
Annals of the rheumatic diseases, 2016Co-Authors: Ronald F. Van VollenhovenAbstract:> ‘All other things being equal, we may assume the superiority of the demonstration which derives from fewer postulates or hypotheses’—Aristotle Therapeutic options for systemic lupus erythematosus (SLE) are still limited. A number of conventional immunosuppressives are used along with glucocorticoids and antimalarials, but the successes of biological therapies in the arthritides have not been duplicated for SLE. To date, only one biologic succeeded in phase III Trials1 ,2 and was approved for use in SLE, but its proper role in the overall management of the patient with SLE has remained incompletely defined.3 Rituximab is used off-label on the strength of many observational studies,4 ,5 but two large Trials failed to demonstrate efficacy.6 ,7 A distressingly large number of biologics failed in late-stage Trials, where some have completely disappeared from further consideration (the B-cell tolerising oligonucleotide construct abetimus,8 the anti-CD20 monoclonal ocrelizumab9); for some others, the future looks bleak (the BLyS antagonist tabalumab,10 ,11 the anti-CD22 monoclonal epratuzumab) and for yet others, investigators and sponsors are struggling to find the best way forward (the T-cell costimulation blocker abatacept,12 ,13 the BLyS/APRIL antagonist atacicept14 ,15). The failure of many SLE Trials may have been due, at least in part, to the simple fact that the drugs being studied were not very effective, but it has also been suggested that clinical Trial methodology for SLE has been suboptimal. Any positive or Successful Trial could therefore give us the dual benefit of moving the field forward with a new compound, while also providing us with useful lessons for the design of clinical Trials. The interferon (IFN) system has been identified as a key pathway in the immunopathogenesis of SLE.16–22 It was therefore logical to develop specific IFN …
Ehab Shiban - One of the best experts on this subject based on the ideXlab platform.
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High-frequency spinal cord stimulation in failed back surgery syndrome patients with predominant low back pain—single-center experience
Neurosurgical Review, 2021Co-Authors: Stefan Motov, Kaywan Aftahy, Ann-kathrin Jörger, Arthur Wagner, Bernhard Meyer, Ehab ShibanAbstract:Treatment of patients with failed back surgery syndrome (FBSS) with predominant low back pain (LBP) remains challenging. High-frequency spinal cord stimulation (HF10 SCS) is believed to achieve significant pain reduction. We aimed to evaluate the real-life efficacy of HF-10 SCS in a tertiary spine center. A prospective observational study of all patients with FBSS and predominant LBP who underwent HF-10 SCS surgery was performed between 2016 and 2018. Patients > 18 years with Visual Analogue Scale (VAS) scores of ≥ 5 for LBP and pain duration > 6 months under stable medication were implanted percutaneous under general anesthesia and a Trial phase of 7–14 days was accomplished. Primary end point was a Successful Trial defined as ≥ 50% VAS score reduction for LBP. Thirty-four of 39 (85%) subjects had a Successful Trial. Fifty-three percent were female and the mean age was 69 years. Median follow-up lasted for 10 months. Devices were removed after a median of 10 months in 5 cases. Remaining 29 patients stated significant VAS score reduction for LBP from 8.1 to 2.9 and VAS for leg pain from 4.9 to 2.2. Twenty-four percent of all patients were able to discontinue their opioids. Eight of 9 patients (89%) with signs of adjacent disc disease and 7 of 10 (70%) patients with hardware failure were Successfully implanted with significant VAS reduction for LBP. HF-10 SCS achieves significant pain reduction in most patients with FBSS and predominant LBP. It might be an efficient alternative to revision surgery.
Eric Hurtado - One of the best experts on this subject based on the ideXlab platform.
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Does spinal anesthesia lead to postoperative urinary retention in same-day urogynecology surgery? A retrospective review.
International urogynecology journal, 2019Co-Authors: Alexandriah N. Alas, Ryan Hidalgo, Luis Espaillat, Hemikaa Devakumar, G. Willy Davila, Eric HurtadoAbstract:Spinal anesthesia has been reported to be a risk factor for postoperative urinary retention (POUR) in various surgical specialties. We hypothesized that spinal anesthesia was a risk factor for POUR after outpatient vaginal surgery for pelvic organ prolapse (POP). This was a retrospective review of an urogynecology database for all outpatient POP vaginal surgeries performed in 2014 to evaluate the risk of POUR after general versus spinal anesthesia. A standardized voiding Trial was performed by backfilling the bladder with 300 ml of saline. A Successful Trial was achieved if the patient voided two-thirds of the total volume instilled, confirmed by bladder ultrasound. Our primary outcome was to compare POUR requiring discharge with a Foley catheter between spinal and general anesthesia. Multivariate logistic regression was performed for variables with significance at p
