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Zhen Huang - One of the best experts on this subject based on the ideXlab platform.

  • Mass Transfer Models for Supercritical Fluid Extraction
    Food Engineering Series, 2014
    Co-Authors: Zhen Huang
    Abstract:

    Extraction of bioactive species from various plant matrices by means of Supercritical Fluids has been widely investigated during the last few decades. In this chapter, recent advances of mass transfer models for representing kinetics of Supercritical Fluid Extraction processes have been summarized. The mass transfer models reviewed here include the most successful broken and intact cell model, the shrinking core model, the microstructured mathematical model, the heat analogue diffusion model and other relatively simple models. Supercritical Fluid Extraction of botanical matters may be influenced by the solute solubility limitation, solute–solid interactions, solid phase mass transfer coefficient and Fluid phase mass transfer coefficient, along with axial dispersion coefficient. Due to the limitations arising from complicated microstructures of plant matrices, sample pretreatments and optimization methods, further attempts are still requiring for developing theoretical mass transfer models for scaling-up and commercialization design of kinetic Supercritical Fluid Extraction processes.

  • Theoretical models for Supercritical Fluid Extraction
    Journal of Chromatography A, 2012
    Co-Authors: Zhen Huang, Xiao-han Shi, Wei-juan Jiang
    Abstract:

    For the proper design of Supercritical Fluid Extraction processes, it is essential to have a sound knowledge of the mass transfer mechanism of the Extraction process and the appropriate mathematical representation. In this paper, the advances and applications of kinetic models for describing Supercritical Fluid Extraction from various solid matrices have been presented. The theoretical models overviewed here include the hot ball diffusion, broken and intact cell, shrinking core and some relatively simple models. Mathematical representations of these models have been in detail interpreted as well as their assumptions, parameter identifications and application examples. Extraction process of the analyte solute from the solid matrix by means of Supercritical Fluid includes the dissolution of the analyte from the solid, the analyte diffusion in the matrix and its transport to the bulk Supercritical Fluid. Mechanisms involved in a mass transfer model are discussed in terms of external mass transfer resistance, internal mass transfer resistance, solute-solid interactions and axial dispersion. The correlations of the external mass transfer coefficient and axial dispersion coefficient with certain dimensionless numbers are also discussed. Among these models, the broken and intact cell model seems to be the most relevant mathematical model as it is able to provide realistic description of the plant material structure for better understanding the mass-transfer kinetics and thus it has been widely employed for modeling Supercritical Fluid Extraction of natural matters.

Alejandro Cifuentes - One of the best experts on this subject based on the ideXlab platform.

  • recent applications of on line Supercritical Fluid Extraction coupled to advanced analytical techniques for compounds Extraction and identification
    IEEE Journal of Solid-state Circuits, 2019
    Co-Authors: A P Sanchezcamargo, Elena Ibanez, Fabian Paradaalonso, Alejandro Cifuentes
    Abstract:

    In a previous review (Sanchez-Camargo et al., J. Sep. Sci. 40 (2017) 213-227), we discussed the application of on-line Supercritical Fluid Extraction coupled to chromatographic techniques. This review includes an update of the most recent publications (from January 2016 till June 2018) on this topic, which employs advanced analytical techniques for extracting and identifying valuable analytes. Supercritical Fluid Extraction has been widely recognized as a green sample preparation technique, because it is efficient, environmentally friendly, powerful, and faster, offering the possibility of direct coupling to analytical instrumental techniques. Among those techniques, Supercritical Fluid chromatography has experienced an innovative progression in the last 10 years, and the most recent applications of Supercritical Fluid Extraction are coupled to this advanced analytical tool. The general principles, both methodological and instrumental of on-line Supercritical Fluid Extraction coupled to Supercritical Fluid chromatography are described here. Besides, applications of the mentioned coupling for analysing biological Fluids, food, soil, and botanical samples are also presented and discussed. Finally, a brief description about the very recent on-line coupling of Supercritical Fluid Extraction to ion mobility spectrometry is presented, as well as concluding remarks about the importance of using these coupled techniques in the near future.

  • On‐line coupling of Supercritical Fluid Extraction and chromatographic techniques
    Journal of Separation Science, 2016
    Co-Authors: Andrea Del Pilar Sánchez-camargo, Fabián Parada-alfonso, Elena Ibanez, Alejandro Cifuentes
    Abstract:

    This review summarizes and discusses recent advances and applications of on-line Supercritical Fluid Extraction coupled to liquid chromatography, gas chromatography and Supercritical Fluid chromatographic techniques. Supercritical Fluids, due to their exceptional physical properties, provide unique opportunities not only during the Extraction step but also in the separation process. Although Supercritical Fluid Extraction is especially suitable for recovery of non-polar organic compounds, this technique can also be successfully applied to the Extraction of polar analytes by the aid of modifiers. Supercritical Fluid Extraction process can be performed following “off-line” or “on-line” approaches and their main features are contrasted herein. Besides, the parameters affecting the Supercritical Fluid Extraction process are explained and a “decision tree” is for the first time presented in this review work as a guide tool for method development. The general principles (instrumental and methodological) of the different on-line couplings of Supercritical Fluid Extraction with chromatographic techniques are described. Advantages and shortcomings of Supercritical Fluid Extraction as hyphenated technique are discussed. Besides, an update of the most recent applications (from 2005 up to now) of the mentioned couplings is also presented in this review. This article is protected by copyright. All rights reserved

Shi Bing - One of the best experts on this subject based on the ideXlab platform.

Xu Song-lin - One of the best experts on this subject based on the ideXlab platform.

Shi Bingjie - One of the best experts on this subject based on the ideXlab platform.