The Experts below are selected from a list of 6 Experts worldwide ranked by ideXlab platform

Tarik F. Massoud - One of the best experts on this subject based on the ideXlab platform.

  • tortuosity of Superior Cerebral Veins comparative magnetic resonance imaging morphometrics in normal subjects and arteriovenous malformation patients
    Clinical Anatomy, 2020
    Co-Authors: Nicholas A Telischak, Vivek Yedavalli, Tarik F. Massoud
    Abstract:

    : Blood vessel tortuosity results from increased diameter and length in response to higher hemodynamic loads. Tortuosity metrics have not been determined for abnormal Superior Cerebral Veins (SCVs) draining Cerebral arteriovenous malformations (AVMs). Draining vein (DV) tortuosity may influence safety and efficacy of retrograde microcatheter navigation during transvenous treatment of pial AVMs. Here, we quantify SCV tortuosity in normal subjects and AVM patients using two image segmentation methods. We used contrast-enhanced brain magnetic resonance (MR) images to define the axis of each SCV through a regularly spaced set of three-dimensional (3D) points defining its skeleton curve. We then calculated two metrics: the "sum of angles metric" (SOAM), which adds all angles of curvature along a vessel and normalizes by vessel length, and the "distance metric" (DM), a tortuosity measure providing a ratio of vessel length to linear distance between vessel endpoints. We analyzed 168 metrics in 43 Veins of eight normal subjects and 41 Veins of seven AVM patients. In normal subjects, the mean SOAM and DM for SCVs were 21.34 ± 7.49 °/mm and 1.42 ± 0.25, respectively. In AVM patients, DVs had a significantly higher mean SOAM of 30.43 ± 11.38 °/mm (p = .02) and DM of 2.79 ± 1.77 (p = .01) than normal subjects. In AVM patients, DVs were significantly more tortuous than matched contralateral uninvolved SCVs, which were similar in tortuosity to normal subject SCVs. We thus report normative tortuosity metrics of brain SCVs and show that AVM cortical DVs are significantly more tortuous than normal SCVs. Knowledge of these comparative tortuosities is valuable in planning endovenous AVM embolotherapies.

Nicholas A Telischak - One of the best experts on this subject based on the ideXlab platform.

  • tortuosity of Superior Cerebral Veins comparative magnetic resonance imaging morphometrics in normal subjects and arteriovenous malformation patients
    Clinical Anatomy, 2020
    Co-Authors: Nicholas A Telischak, Vivek Yedavalli, Tarik F. Massoud
    Abstract:

    : Blood vessel tortuosity results from increased diameter and length in response to higher hemodynamic loads. Tortuosity metrics have not been determined for abnormal Superior Cerebral Veins (SCVs) draining Cerebral arteriovenous malformations (AVMs). Draining vein (DV) tortuosity may influence safety and efficacy of retrograde microcatheter navigation during transvenous treatment of pial AVMs. Here, we quantify SCV tortuosity in normal subjects and AVM patients using two image segmentation methods. We used contrast-enhanced brain magnetic resonance (MR) images to define the axis of each SCV through a regularly spaced set of three-dimensional (3D) points defining its skeleton curve. We then calculated two metrics: the "sum of angles metric" (SOAM), which adds all angles of curvature along a vessel and normalizes by vessel length, and the "distance metric" (DM), a tortuosity measure providing a ratio of vessel length to linear distance between vessel endpoints. We analyzed 168 metrics in 43 Veins of eight normal subjects and 41 Veins of seven AVM patients. In normal subjects, the mean SOAM and DM for SCVs were 21.34 ± 7.49 °/mm and 1.42 ± 0.25, respectively. In AVM patients, DVs had a significantly higher mean SOAM of 30.43 ± 11.38 °/mm (p = .02) and DM of 2.79 ± 1.77 (p = .01) than normal subjects. In AVM patients, DVs were significantly more tortuous than matched contralateral uninvolved SCVs, which were similar in tortuosity to normal subject SCVs. We thus report normative tortuosity metrics of brain SCVs and show that AVM cortical DVs are significantly more tortuous than normal SCVs. Knowledge of these comparative tortuosities is valuable in planning endovenous AVM embolotherapies.

Vivek Yedavalli - One of the best experts on this subject based on the ideXlab platform.

  • tortuosity of Superior Cerebral Veins comparative magnetic resonance imaging morphometrics in normal subjects and arteriovenous malformation patients
    Clinical Anatomy, 2020
    Co-Authors: Nicholas A Telischak, Vivek Yedavalli, Tarik F. Massoud
    Abstract:

    : Blood vessel tortuosity results from increased diameter and length in response to higher hemodynamic loads. Tortuosity metrics have not been determined for abnormal Superior Cerebral Veins (SCVs) draining Cerebral arteriovenous malformations (AVMs). Draining vein (DV) tortuosity may influence safety and efficacy of retrograde microcatheter navigation during transvenous treatment of pial AVMs. Here, we quantify SCV tortuosity in normal subjects and AVM patients using two image segmentation methods. We used contrast-enhanced brain magnetic resonance (MR) images to define the axis of each SCV through a regularly spaced set of three-dimensional (3D) points defining its skeleton curve. We then calculated two metrics: the "sum of angles metric" (SOAM), which adds all angles of curvature along a vessel and normalizes by vessel length, and the "distance metric" (DM), a tortuosity measure providing a ratio of vessel length to linear distance between vessel endpoints. We analyzed 168 metrics in 43 Veins of eight normal subjects and 41 Veins of seven AVM patients. In normal subjects, the mean SOAM and DM for SCVs were 21.34 ± 7.49 °/mm and 1.42 ± 0.25, respectively. In AVM patients, DVs had a significantly higher mean SOAM of 30.43 ± 11.38 °/mm (p = .02) and DM of 2.79 ± 1.77 (p = .01) than normal subjects. In AVM patients, DVs were significantly more tortuous than matched contralateral uninvolved SCVs, which were similar in tortuosity to normal subject SCVs. We thus report normative tortuosity metrics of brain SCVs and show that AVM cortical DVs are significantly more tortuous than normal SCVs. Knowledge of these comparative tortuosities is valuable in planning endovenous AVM embolotherapies.

Paolo G Nucifora - One of the best experts on this subject based on the ideXlab platform.

  • the eagle sign of radiologic diagnosis aids in the management of spontaneous intracranial hypotension a case report
    2014
    Co-Authors: Joseph C Wildenberg, Seetharam C Chadalavada, Scott Akers, Pratap M Yagnik, Paolo G Nucifora
    Abstract:

     Abstract—Spontaneous intracranial hypotension can occur without preceding trauma or medical intervention. Patients often present with positional headaches but may be misdiagnosed with migraines/tension headaches due to a lack of clinical suspicion. Neuroimaging is likely to be the first step in diagnosis and is highly accurate. We present a 31-year old man with spontaneous intracranial hypotension who was admitted with positional headaches and concerning findings on a head CT. Additional imaging revealed classic findings of intracranial hypotension including separation of the Superior Cerebral Veins from the sagittal sinus. A thoracic spine MRI showed an epidural fluid collection suggestive of a CSF leak. The patient was treated with an epidural blood patch and his symptoms improved.

Joseph C Wildenberg - One of the best experts on this subject based on the ideXlab platform.

  • the eagle sign of radiologic diagnosis aids in the management of spontaneous intracranial hypotension a case report
    2014
    Co-Authors: Joseph C Wildenberg, Seetharam C Chadalavada, Scott Akers, Pratap M Yagnik, Paolo G Nucifora
    Abstract:

     Abstract—Spontaneous intracranial hypotension can occur without preceding trauma or medical intervention. Patients often present with positional headaches but may be misdiagnosed with migraines/tension headaches due to a lack of clinical suspicion. Neuroimaging is likely to be the first step in diagnosis and is highly accurate. We present a 31-year old man with spontaneous intracranial hypotension who was admitted with positional headaches and concerning findings on a head CT. Additional imaging revealed classic findings of intracranial hypotension including separation of the Superior Cerebral Veins from the sagittal sinus. A thoracic spine MRI showed an epidural fluid collection suggestive of a CSF leak. The patient was treated with an epidural blood patch and his symptoms improved.