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Jennifer A Mccannbrown - One of the best experts on this subject based on the ideXlab platform.
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short and long term retrievability of the celect vena cava filter results from a multi institutional registry
Journal of Vascular and Interventional Radiology, 2009Co-Authors: Stuart M Lyon, Guillermo Elizondo Riojas, Mario Enrique Baltazares Lipp, Raman Uberoi, Graham R Plant, Jai Patel, William D Voorhees, Miguel Angel De Gregorio, R W Gunther, Jennifer A MccannbrownAbstract:Purpose To evaluate retrievability of the Celect vena cava filter over time and to assess the safety of the retrieval procedure in a prospective multicenter registry. Materials and Methods Between October 2005 and March 2008, Celect filters were placed in 95 patients (61 men; mean age, 51 years ± 18.5) with a temporary need for an inferior vena cava (IVC) filter. All patients satisfied requirements for filter placement; the primary indications for placement were pulmonary embolism (PE) with a contraindication to or failure of anticoagulation ( n = 40), high risk for further PE ( n = 29), trauma ( n = 23), or massive PE with residual deep vein thrombosis and risk for further PE ( n = 3). Filter orientation, vena cava injury, and other device-related incidents were evaluated at implantation and retrieval. The degree of difficulty associated with retrieval was also assessed. Results Filter retrieval was attempted in 58 patients (mean indwell time of 179 days; median, 168.5 d; range, 5–466 d). Fifty-six filters (96.6%) were successfully retrieved. Unsuccessful retrieval attempts were attributed to filter tilt ( n = 1) or excessive tissue growth with the hook embedded in the endothelium ( n = 1). No adverse events were associated with the inability to retrieve these filters. A Kaplan-Meier product-limit Survival Estimate revealed that the probability of successful filter retrieval remained at 100% at 50 weeks and at more than 74% at 55 weeks after implantation. No adverse events were related to the retrieval procedures. Conclusions Retrieval of the Celect filter was performed safely as long as 466 days after implantation.
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long term retrieval success rate profile for the gunther tulip vena cava filter
Journal of Vascular and Interventional Radiology, 2009Co-Authors: Bob H Smouse, Michael F Knox, Robert G Dixon, William D Voorhees, David Rosenthal, Jennifer A MccannbrownAbstract:Purpose To evaluate the likelihood of successful retrieval of the Gunther Tulip vena cava filter after various implant durations (up to 494 days). Materials and Methods Retrievable Gunther Tulip filters were placed in 554 patients. All patients satisfied requirements for filter placement; the primary indication for placement was specified for 394 patients (71%), as follows: unspecified trauma ( n = 164), bariatric procedures ( n = 128), orthopedic procedures ( n = 36), and other ( n = 66). Filter tilt and vena cava injury were assessed at implantation. Filters were not repositioned after placement. At retrieval, filter orientation, vena cava injury, other device-related incidents, and the degree of difficulty associated with retrieval were reported. Results Filter retrieval was attempted in 275 patients and successful in 248 (90.2%). The mean filter indwell time was 58.9 days (range, 3–494 days). Unsuccessful retrievals ( n = 27) were attributed primarily to improper hook orientation ( n = 10) or excessive tissue in-growth at the filter legs ( n = 16). Of the remaining 279 patients, 223 withdrew from the study, 41 were associated with a decision to keep the filter as a permanent device, 13 died for reasons unrelated to the study, and two had no reported endpoint data. A Kaplan-Meier product-limit Survival Estimate revealed that the probability of successful device retrieval remained greater than 94% at 12 weeks and greater than 67% at 26 weeks. Conclusions This study contributes to the body of clinical data related to retrievable filters, demonstrating reliable retrieval rates at 12 weeks, with successful retrievals up to 17 months after implantation.
William D Voorhees - One of the best experts on this subject based on the ideXlab platform.
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short and long term retrievability of the celect vena cava filter results from a multi institutional registry
Journal of Vascular and Interventional Radiology, 2009Co-Authors: Stuart M Lyon, Guillermo Elizondo Riojas, Mario Enrique Baltazares Lipp, Raman Uberoi, Graham R Plant, Jai Patel, William D Voorhees, Miguel Angel De Gregorio, R W Gunther, Jennifer A MccannbrownAbstract:Purpose To evaluate retrievability of the Celect vena cava filter over time and to assess the safety of the retrieval procedure in a prospective multicenter registry. Materials and Methods Between October 2005 and March 2008, Celect filters were placed in 95 patients (61 men; mean age, 51 years ± 18.5) with a temporary need for an inferior vena cava (IVC) filter. All patients satisfied requirements for filter placement; the primary indications for placement were pulmonary embolism (PE) with a contraindication to or failure of anticoagulation ( n = 40), high risk for further PE ( n = 29), trauma ( n = 23), or massive PE with residual deep vein thrombosis and risk for further PE ( n = 3). Filter orientation, vena cava injury, and other device-related incidents were evaluated at implantation and retrieval. The degree of difficulty associated with retrieval was also assessed. Results Filter retrieval was attempted in 58 patients (mean indwell time of 179 days; median, 168.5 d; range, 5–466 d). Fifty-six filters (96.6%) were successfully retrieved. Unsuccessful retrieval attempts were attributed to filter tilt ( n = 1) or excessive tissue growth with the hook embedded in the endothelium ( n = 1). No adverse events were associated with the inability to retrieve these filters. A Kaplan-Meier product-limit Survival Estimate revealed that the probability of successful filter retrieval remained at 100% at 50 weeks and at more than 74% at 55 weeks after implantation. No adverse events were related to the retrieval procedures. Conclusions Retrieval of the Celect filter was performed safely as long as 466 days after implantation.
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long term retrieval success rate profile for the gunther tulip vena cava filter
Journal of Vascular and Interventional Radiology, 2009Co-Authors: Bob H Smouse, Michael F Knox, Robert G Dixon, William D Voorhees, David Rosenthal, Jennifer A MccannbrownAbstract:Purpose To evaluate the likelihood of successful retrieval of the Gunther Tulip vena cava filter after various implant durations (up to 494 days). Materials and Methods Retrievable Gunther Tulip filters were placed in 554 patients. All patients satisfied requirements for filter placement; the primary indication for placement was specified for 394 patients (71%), as follows: unspecified trauma ( n = 164), bariatric procedures ( n = 128), orthopedic procedures ( n = 36), and other ( n = 66). Filter tilt and vena cava injury were assessed at implantation. Filters were not repositioned after placement. At retrieval, filter orientation, vena cava injury, other device-related incidents, and the degree of difficulty associated with retrieval were reported. Results Filter retrieval was attempted in 275 patients and successful in 248 (90.2%). The mean filter indwell time was 58.9 days (range, 3–494 days). Unsuccessful retrievals ( n = 27) were attributed primarily to improper hook orientation ( n = 10) or excessive tissue in-growth at the filter legs ( n = 16). Of the remaining 279 patients, 223 withdrew from the study, 41 were associated with a decision to keep the filter as a permanent device, 13 died for reasons unrelated to the study, and two had no reported endpoint data. A Kaplan-Meier product-limit Survival Estimate revealed that the probability of successful device retrieval remained greater than 94% at 12 weeks and greater than 67% at 26 weeks. Conclusions This study contributes to the body of clinical data related to retrievable filters, demonstrating reliable retrieval rates at 12 weeks, with successful retrievals up to 17 months after implantation.
Stephan Kische - One of the best experts on this subject based on the ideXlab platform.
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results of endovascular repair of the thoracic aorta with the talent thoracic stent graft the talent thoracic retrospective registry
The Journal of Thoracic and Cardiovascular Surgery, 2006Co-Authors: Rossella Fattori, Christoph A Nienaber, Herve Rousseau, Jeanpaul Beregi, Robin H Heijmen, Martin Grabenwoger, Philippe Piquet, Luigi Lovato, Chaouki Dabbech, Stephan KischeAbstract:Background Endovascular treatment of thoracic aortic diseases demonstrated low perioperative morbidity and mortality when compared with conventional open repair. Long-term effectiveness of this minimally invasive technique remains to be proven. The Talent Thoracic Retrospective Registry was designed to evaluate the impact of this therapy on patients treated in 7 major European referral centers over an 8-year period. Methods Data from 457 consecutive patients (113 emergency and 344 elective cases) who underwent endovascular thoracic aortic repair with the Medtronic Talent Thoracic stent graft (Medtronic/AVE, Santa Rosa, Calif) were collected. Follow-up analysis (24 ± 19.4 months, range 1-85.1 months) was based on clinical and imaging findings, including all adverse events. To ensure consistency of data interpretation and event reporting, one physician reviewed all adverse events and deaths for the whole cohort of patients. In the case of discrepancies, the treating physicians were queried. Findings Among 422 patients who survived the interventional procedure (in-hospital mortality 5%, 23 patients), mortality during follow-up was 8.5% (36 patients), and in 11 of them the death was related to the aortic disease. Persistent endoleak was reported at imaging follow-up in 64 cases: 44 were primary (9.6%) and 21 occurred during follow-up (4.9%). Seven patients with persistent endoleak had aortic rupture during follow-up, at a variable time from 40 days to 35 months, and all subsequently died. A minor incidence of migration of the stent graft (7 cases), graft fabric alteration (2 cases), and modular disconnection (3 cases) was observed at imaging. Kaplan-Meier overall Survival Estimate at 1 year was 90.97%, at 3 years was 85.36%, and at 5 years was 77.49%. At the same intervals, freedom from a second procedure (either open conversion or endovascular) was 92.45%, 81.3%, and 70.0%, respectively. Conclusion Endovascular treatment for thoracic aortic disease with the Talent stent graft is associated with low early morbidity and mortality rates also for patients who are at high risk and treated on an emergency basis. Follow-up data indicate a substantial durability of the procedure with a high freedom from related death and secondary interventions.
Stuart M Lyon - One of the best experts on this subject based on the ideXlab platform.
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short and long term retrievability of the celect vena cava filter results from a multi institutional registry
Journal of Vascular and Interventional Radiology, 2009Co-Authors: Stuart M Lyon, Guillermo Elizondo Riojas, Mario Enrique Baltazares Lipp, Raman Uberoi, Graham R Plant, Jai Patel, William D Voorhees, Miguel Angel De Gregorio, R W Gunther, Jennifer A MccannbrownAbstract:Purpose To evaluate retrievability of the Celect vena cava filter over time and to assess the safety of the retrieval procedure in a prospective multicenter registry. Materials and Methods Between October 2005 and March 2008, Celect filters were placed in 95 patients (61 men; mean age, 51 years ± 18.5) with a temporary need for an inferior vena cava (IVC) filter. All patients satisfied requirements for filter placement; the primary indications for placement were pulmonary embolism (PE) with a contraindication to or failure of anticoagulation ( n = 40), high risk for further PE ( n = 29), trauma ( n = 23), or massive PE with residual deep vein thrombosis and risk for further PE ( n = 3). Filter orientation, vena cava injury, and other device-related incidents were evaluated at implantation and retrieval. The degree of difficulty associated with retrieval was also assessed. Results Filter retrieval was attempted in 58 patients (mean indwell time of 179 days; median, 168.5 d; range, 5–466 d). Fifty-six filters (96.6%) were successfully retrieved. Unsuccessful retrieval attempts were attributed to filter tilt ( n = 1) or excessive tissue growth with the hook embedded in the endothelium ( n = 1). No adverse events were associated with the inability to retrieve these filters. A Kaplan-Meier product-limit Survival Estimate revealed that the probability of successful filter retrieval remained at 100% at 50 weeks and at more than 74% at 55 weeks after implantation. No adverse events were related to the retrieval procedures. Conclusions Retrieval of the Celect filter was performed safely as long as 466 days after implantation.
Liisa Volin - One of the best experts on this subject based on the ideXlab platform.
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Ex vivo and in vivo T cell-depleted allogeneic stem cell transplantation in patients with acute myeloid leukemia in first complete remission resulted in similar overall Survival: on behalf of the ALWP of the EBMT and the MSKCC
Journal of Hematology and Oncology, 2018Co-Authors: Florent Malard, Myriam Labopin, Christina Cho, Didier Blaise, Esperanza B. Papadopoulos, Jakob Passweg, Richard O'reilly, Edouard Forcade, Molly Maloy, Liisa VolinAbstract:BackgroundGraft-versus-host disease (GVHD) is one of the leading causes of non-relapse mortality and morbidity after allogeneic hematopoietic stem cell transplantation (allo-HCT).MethodsWe evaluated the outcomes of two well-established strategies used for GVHD prevention: in vivo T cell depletion using antithymocyte globulin (ATG) and ex vivo T cell depletion using a CD34-selected (CD34+) graft. A total of 525 adult patients (363 ATG, 162 CD34+) with intermediate or high-risk cytogenetics acute myeloid leukemia (AML) in first complete remission (CR1) were included. Patients underwent myeloablative allo-HCT using matched related or unrelated donors.ResultsTwo-year overall Survival Estimate was 69.9% (95% CI, 58.5-69.4) in the ATG group and 67.6% (95% CI, 60.3-74.9) in the CD34+ group (p=0.31). The cumulative incidence of grade II-IV acute GVHD and chronic GVHD was higher in the ATG cohort [HR 2.0 (95% CI 1.1-3.7), p=0.02; HR 15.1 (95% CI 5.3-42.2), p
