The Experts below are selected from a list of 138 Experts worldwide ranked by ideXlab platform
Maragaret A Reddy - One of the best experts on this subject based on the ideXlab platform.
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malignant nodular hidradenoma of the eyelid a rare Sweat Gland Tumor
Middle East African Journal of Ophthalmology, 2010Co-Authors: Abdulla Al Baghli, Suresh S Reddy, Maragaret A ReddyAbstract:We report a case of malignant nodular hidradenoma in a middle-aged man, who presented with a nodular swelling in the eyelid. The Tumor was similar to its benign counterpart but had additional features such as surface ulceration, numerous mitiotic figures, and an infiltrative growth pattern. Malignant forms of hidradenomas are unusual and the possibility this variant should be considered in the differential diagnosis of eyelid Tumors.
Abdulla Al Baghli - One of the best experts on this subject based on the ideXlab platform.
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malignant nodular hidradenoma of the eyelid a rare Sweat Gland Tumor
Middle East African Journal of Ophthalmology, 2010Co-Authors: Abdulla Al Baghli, Suresh S Reddy, Maragaret A ReddyAbstract:We report a case of malignant nodular hidradenoma in a middle-aged man, who presented with a nodular swelling in the eyelid. The Tumor was similar to its benign counterpart but had additional features such as surface ulceration, numerous mitiotic figures, and an infiltrative growth pattern. Malignant forms of hidradenomas are unusual and the possibility this variant should be considered in the differential diagnosis of eyelid Tumors.
Michael Wallace - One of the best experts on this subject based on the ideXlab platform.
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widespread metastatic eccrine porocarcinoma
Journal of The American Academy of Dermatology, 2003Co-Authors: Rajat Goel, Melissa J Contos, Michael WallaceAbstract:Abstract Eccrine porocarcinoma is a rare malignant Sweat Gland Tumor arising from the acrosyringium. These lesions can show multiple epidermotropic metastases, however, systemic spread is rare. We describe the case of a 42-year-old African American man who presented in February 1998 with a lesion on the plantar surface of his right foot that was diagnosed as an eccrine porocarcinoma. Subsequently, during the next year, cutaneous metastases developed to his left shoulder and flank. Two years after his initial presentation, he was admitted with an esophageal mass and multiple gastric ulcers. Biopsy specimens of these lesions demonstrated metastatic eccrine porocarcinoma. Further evaluation revealed multiple metastases to lymph nodes, lungs, and brain. Histologic examination revealed nests of basaloid cells with eosinophilic cytoplasm and intracellular ductlike lumina lined by eosinophilic basement membranelike material. These ductular structures where highlighted by immunohistochemical stains for carcinoembryonic antigen, confirming their eccrine differentiation. There were mitotic figures and individual cell necrosis. Although rare, systemic metastases from an eccrine porocarcinoma must enter the differential diagnoses of a Tumor mass in such patients.
Suresh S Reddy - One of the best experts on this subject based on the ideXlab platform.
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malignant nodular hidradenoma of the eyelid a rare Sweat Gland Tumor
Middle East African Journal of Ophthalmology, 2010Co-Authors: Abdulla Al Baghli, Suresh S Reddy, Maragaret A ReddyAbstract:We report a case of malignant nodular hidradenoma in a middle-aged man, who presented with a nodular swelling in the eyelid. The Tumor was similar to its benign counterpart but had additional features such as surface ulceration, numerous mitiotic figures, and an infiltrative growth pattern. Malignant forms of hidradenomas are unusual and the possibility this variant should be considered in the differential diagnosis of eyelid Tumors.
Anita Mahadevan - One of the best experts on this subject based on the ideXlab platform.
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managing a rare malignant Sweat Gland Tumor invading the brain case report and literature review
World Neurosurgery, 2016Co-Authors: Aniruddha Tekkatte Jagannatha, Mansoor A Khan, Shrithi Karanth, Umesh Srikantha, Ravi Gopal Varma, Anita MahadevanAbstract:Background Malignant Sweat Gland adnexal Tumors are rare with an incidence of 0.001%. Of these, clear cell hidradenocarcinoma is an extremely uncommon subtype that accounts for 6% of malignant eccrine Sweat Gland Tumors. They occur commonly in the head, neck, and extremities. Although they have a propensity for local recurrence, intracranial extension with brain invasion is extremely rare. Case Description We report a 76-year-old man with a large, recurring, ulcerated, fungating scalp swelling of 14 years who presented with focal seizures and drowsiness. Neuroimaging revealed a massive Tumor arising from the scalp to invade the left parietal lobe and extending to the right side with occlusion of the superior sagittal sinus. The overlying parietal bone was lytic with a “moth-eaten” appearance. He underwent wide excision of the scalp lesion, near-total cerebral Tumor decompression followed by titanium mesh cranioplasty, rotation flap reconstruction of the scalp, and adjuvant radiotherapy to the skull vault. Histopathology revealed clear cell hidradenocarcinoma. Whole-body positron emission tomography scan did not reveal any other lesion. At 24 months' follow-up, he remains recurrence free. Conclusion We report a rare indolent case of clear cell hidradenocarcinoma invading the brain, which was managed with near-total decompression and adjuvant radiotherapy. Intracranial extension in such aggressive Tumors poses challenges in management, and regular neuroimaging surveillance is advised.
