Symphytum

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Bilge Sener - One of the best experts on this subject based on the ideXlab platform.

  • A bidesmosidic hederagenin hexasaccharide from the roots of Symphytum officinale.
    Phytochemistry, 1995
    Co-Authors: Faryal Vali Mohammad, Viqar Uddin Ahmad, Mushtaq Noorwala, Bilge Sener
    Abstract:

    Abstract A new bidesmosidic triterpenoidal saponin 3-O-[β- d -glucopyranosyl -(1 → 4)-β- d -glucopyranosyl -(1 → 4)-α- l - -arabinopyranosyl ]- hederagenin -28-O-[α- l -rhamnopyranosyl -(1 → 4)-β- d -glucopyranosyl -(1 → 6)-β- d - glucopyranosyl ] ester, was isolated from the roots of Symphytum officinale. The structure was assigned by chemical methods and spectral analysis (1H, 13C, DEPT, NMR, EI-MS and FAB-MS) including 1H1H COSY, 1H13C COSY and HOHAHA. The prosapogenin of this saponin is also a new compound.

  • A bidesmosidic triterpene glycoside from the roots of Symphytum officinale
    Phytochemistry, 1994
    Co-Authors: Mushtaq Noorwala, Viqar Uddin Ahmad, Faryal Vali Mohammad, Bilge Sener
    Abstract:

    A new bidesmosidic triterpenoidal saponin of hederagenin was isolated from the ethanolic extract of the roots of Symphytum officinale L. Its structure was elucidated by using 1H NMR, 1H-1H COSY NMR, heteronuclear 1H-13C correlated spectroscopy (heteroCOSY), 13C NMR, DEPT, FAB mass spectrometry and chemical evidence as 3-O-alpha-L-arabinopyranosyl]-hederagenin-28-O-[beta-D-gluco pyranosyl- (-->4)-beta-D-glucopyranosyl-(1-->6)-beta-D-glucopyranosyl]ester.

  • Symphytoxide A, a triterpenoid saponin from the roots of Symphytum officinale
    Phytochemistry, 1993
    Co-Authors: Viqar Uddin Ahmad, Mushtaq Noorwala, Faryal Vali Mohammad, Bilge Sener, Anwar-ul-hassan Gilan, Khalid Aftab
    Abstract:

    Abstract A new triterpenoidal saponin of hederagenin named symphytoxide A has been isolated from the ethanolic extract of the roots of Symphytum officinale

  • A new triterpene glycoside from the roots of Symphytum officinale.
    Journal of natural products, 1993
    Co-Authors: Viqar Uddin Ahmad, Mushtaq Noorwala, Faryal Vali Mohammad, Bilge Sener
    Abstract:

    Chemical investigation of the EtOH-soluble portion of Symphytum officinale roots has resulted in the isolation of a new pentacyclic triterpene glycoside of oleanolic acid. Its structure was elucidated by spectroscopic studies, including 2D nmr, and chemical evidences as 3-O-[beta-D-glucopyranosyl-(1-->4)-beta-D-glucopyranosyl-(1-->4)-alpha-L -arabinopyranosyl]-oleanolic acid [1].

  • A New Bidesmosidic Triterpenoidal Saponin from the Roots of Symphytum officinale.
    Planta medica, 1993
    Co-Authors: Viqar Uddin Ahmad, Mushtaq Noorwala, Faryal Vali Mohammad, Bilge Sener
    Abstract:

    A new triterpenoidal saponin having hederagenin as the aglycone was isolated from the roots of Symphytum OFFICINALE L. The structure of this saponin was elucidated by FAB-MS, (1)H-, (13)C-NMR, 2D-NMR analyses and chemical studies as 3- O-[beta- D-glucopyranosyl-(1-->4)-alpha- L-arabinopyranosyl]-hederagenin 28- O-[beta- D-glucopyranosyl-(1-->6)-beta- D-glucopyranosyl] ester.

Mushtaq Noorwala - One of the best experts on this subject based on the ideXlab platform.

  • Phyto-Pharmacology of Saponins from Symphytum officinale L.
    Advances in experimental medicine and biology, 1996
    Co-Authors: Khalid Aftab, Mushtaq Noorwala, Faryal Vali Mohammad, Fehmeena Shaheen, V. U. Ahmad
    Abstract:

    Symphytum officinale L. (comfrey) is a plant of Euro-American origin which belongs to the family Boraginaceae 1. It is a part of the practice of naturopathic medicine in Europe and America and is reported to have multiple therapeutic uses2,3,4.5,6 which include antiseptic, analgesic, antiinflammatory and antiulcer properties. It is also considered useful in several skin complications such as chronic wounds, burns, sores, eczema and wrinkles7. Moreover, the roots of this plant are used in he treatment of colds, asthma, bronchitis, tuberculosis, and hemorrhoids8. Comfrey is also. used in kidney diseases, cancer, and anaemia9.

  • A bidesmosidic hederagenin hexasaccharide from the roots of Symphytum officinale.
    Phytochemistry, 1995
    Co-Authors: Faryal Vali Mohammad, Viqar Uddin Ahmad, Mushtaq Noorwala, Bilge Sener
    Abstract:

    Abstract A new bidesmosidic triterpenoidal saponin 3-O-[β- d -glucopyranosyl -(1 → 4)-β- d -glucopyranosyl -(1 → 4)-α- l - -arabinopyranosyl ]- hederagenin -28-O-[α- l -rhamnopyranosyl -(1 → 4)-β- d -glucopyranosyl -(1 → 6)-β- d - glucopyranosyl ] ester, was isolated from the roots of Symphytum officinale. The structure was assigned by chemical methods and spectral analysis (1H, 13C, DEPT, NMR, EI-MS and FAB-MS) including 1H1H COSY, 1H13C COSY and HOHAHA. The prosapogenin of this saponin is also a new compound.

  • A bidesmosidic triterpene glycoside from the roots of Symphytum officinale
    Phytochemistry, 1994
    Co-Authors: Mushtaq Noorwala, Viqar Uddin Ahmad, Faryal Vali Mohammad, Bilge Sener
    Abstract:

    A new bidesmosidic triterpenoidal saponin of hederagenin was isolated from the ethanolic extract of the roots of Symphytum officinale L. Its structure was elucidated by using 1H NMR, 1H-1H COSY NMR, heteronuclear 1H-13C correlated spectroscopy (heteroCOSY), 13C NMR, DEPT, FAB mass spectrometry and chemical evidence as 3-O-alpha-L-arabinopyranosyl]-hederagenin-28-O-[beta-D-gluco pyranosyl- (-->4)-beta-D-glucopyranosyl-(1-->6)-beta-D-glucopyranosyl]ester.

  • Symphytoxide A, a triterpenoid saponin from the roots of Symphytum officinale
    Phytochemistry, 1993
    Co-Authors: Viqar Uddin Ahmad, Mushtaq Noorwala, Faryal Vali Mohammad, Bilge Sener, Anwar-ul-hassan Gilan, Khalid Aftab
    Abstract:

    Abstract A new triterpenoidal saponin of hederagenin named symphytoxide A has been isolated from the ethanolic extract of the roots of Symphytum officinale

  • A new triterpene glycoside from the roots of Symphytum officinale.
    Journal of natural products, 1993
    Co-Authors: Viqar Uddin Ahmad, Mushtaq Noorwala, Faryal Vali Mohammad, Bilge Sener
    Abstract:

    Chemical investigation of the EtOH-soluble portion of Symphytum officinale roots has resulted in the isolation of a new pentacyclic triterpene glycoside of oleanolic acid. Its structure was elucidated by spectroscopic studies, including 2D nmr, and chemical evidences as 3-O-[beta-D-glucopyranosyl-(1-->4)-beta-D-glucopyranosyl-(1-->4)-alpha-L -arabinopyranosyl]-oleanolic acid [1].

Faryal Vali Mohammad - One of the best experts on this subject based on the ideXlab platform.

  • Phyto-Pharmacology of Saponins from Symphytum officinale L.
    Advances in experimental medicine and biology, 1996
    Co-Authors: Khalid Aftab, Mushtaq Noorwala, Faryal Vali Mohammad, Fehmeena Shaheen, V. U. Ahmad
    Abstract:

    Symphytum officinale L. (comfrey) is a plant of Euro-American origin which belongs to the family Boraginaceae 1. It is a part of the practice of naturopathic medicine in Europe and America and is reported to have multiple therapeutic uses2,3,4.5,6 which include antiseptic, analgesic, antiinflammatory and antiulcer properties. It is also considered useful in several skin complications such as chronic wounds, burns, sores, eczema and wrinkles7. Moreover, the roots of this plant are used in he treatment of colds, asthma, bronchitis, tuberculosis, and hemorrhoids8. Comfrey is also. used in kidney diseases, cancer, and anaemia9.

  • A bidesmosidic hederagenin hexasaccharide from the roots of Symphytum officinale.
    Phytochemistry, 1995
    Co-Authors: Faryal Vali Mohammad, Viqar Uddin Ahmad, Mushtaq Noorwala, Bilge Sener
    Abstract:

    Abstract A new bidesmosidic triterpenoidal saponin 3-O-[β- d -glucopyranosyl -(1 → 4)-β- d -glucopyranosyl -(1 → 4)-α- l - -arabinopyranosyl ]- hederagenin -28-O-[α- l -rhamnopyranosyl -(1 → 4)-β- d -glucopyranosyl -(1 → 6)-β- d - glucopyranosyl ] ester, was isolated from the roots of Symphytum officinale. The structure was assigned by chemical methods and spectral analysis (1H, 13C, DEPT, NMR, EI-MS and FAB-MS) including 1H1H COSY, 1H13C COSY and HOHAHA. The prosapogenin of this saponin is also a new compound.

  • A bidesmosidic triterpene glycoside from the roots of Symphytum officinale
    Phytochemistry, 1994
    Co-Authors: Mushtaq Noorwala, Viqar Uddin Ahmad, Faryal Vali Mohammad, Bilge Sener
    Abstract:

    A new bidesmosidic triterpenoidal saponin of hederagenin was isolated from the ethanolic extract of the roots of Symphytum officinale L. Its structure was elucidated by using 1H NMR, 1H-1H COSY NMR, heteronuclear 1H-13C correlated spectroscopy (heteroCOSY), 13C NMR, DEPT, FAB mass spectrometry and chemical evidence as 3-O-alpha-L-arabinopyranosyl]-hederagenin-28-O-[beta-D-gluco pyranosyl- (-->4)-beta-D-glucopyranosyl-(1-->6)-beta-D-glucopyranosyl]ester.

  • Symphytoxide A, a triterpenoid saponin from the roots of Symphytum officinale
    Phytochemistry, 1993
    Co-Authors: Viqar Uddin Ahmad, Mushtaq Noorwala, Faryal Vali Mohammad, Bilge Sener, Anwar-ul-hassan Gilan, Khalid Aftab
    Abstract:

    Abstract A new triterpenoidal saponin of hederagenin named symphytoxide A has been isolated from the ethanolic extract of the roots of Symphytum officinale

  • A new triterpene glycoside from the roots of Symphytum officinale.
    Journal of natural products, 1993
    Co-Authors: Viqar Uddin Ahmad, Mushtaq Noorwala, Faryal Vali Mohammad, Bilge Sener
    Abstract:

    Chemical investigation of the EtOH-soluble portion of Symphytum officinale roots has resulted in the isolation of a new pentacyclic triterpene glycoside of oleanolic acid. Its structure was elucidated by spectroscopic studies, including 2D nmr, and chemical evidences as 3-O-[beta-D-glucopyranosyl-(1-->4)-beta-D-glucopyranosyl-(1-->4)-alpha-L -arabinopyranosyl]-oleanolic acid [1].

Viqar Uddin Ahmad - One of the best experts on this subject based on the ideXlab platform.

  • A bidesmosidic hederagenin hexasaccharide from the roots of Symphytum officinale.
    Phytochemistry, 1995
    Co-Authors: Faryal Vali Mohammad, Viqar Uddin Ahmad, Mushtaq Noorwala, Bilge Sener
    Abstract:

    Abstract A new bidesmosidic triterpenoidal saponin 3-O-[β- d -glucopyranosyl -(1 → 4)-β- d -glucopyranosyl -(1 → 4)-α- l - -arabinopyranosyl ]- hederagenin -28-O-[α- l -rhamnopyranosyl -(1 → 4)-β- d -glucopyranosyl -(1 → 6)-β- d - glucopyranosyl ] ester, was isolated from the roots of Symphytum officinale. The structure was assigned by chemical methods and spectral analysis (1H, 13C, DEPT, NMR, EI-MS and FAB-MS) including 1H1H COSY, 1H13C COSY and HOHAHA. The prosapogenin of this saponin is also a new compound.

  • A bidesmosidic triterpene glycoside from the roots of Symphytum officinale
    Phytochemistry, 1994
    Co-Authors: Mushtaq Noorwala, Viqar Uddin Ahmad, Faryal Vali Mohammad, Bilge Sener
    Abstract:

    A new bidesmosidic triterpenoidal saponin of hederagenin was isolated from the ethanolic extract of the roots of Symphytum officinale L. Its structure was elucidated by using 1H NMR, 1H-1H COSY NMR, heteronuclear 1H-13C correlated spectroscopy (heteroCOSY), 13C NMR, DEPT, FAB mass spectrometry and chemical evidence as 3-O-alpha-L-arabinopyranosyl]-hederagenin-28-O-[beta-D-gluco pyranosyl- (-->4)-beta-D-glucopyranosyl-(1-->6)-beta-D-glucopyranosyl]ester.

  • Symphytoxide A, a triterpenoid saponin from the roots of Symphytum officinale
    Phytochemistry, 1993
    Co-Authors: Viqar Uddin Ahmad, Mushtaq Noorwala, Faryal Vali Mohammad, Bilge Sener, Anwar-ul-hassan Gilan, Khalid Aftab
    Abstract:

    Abstract A new triterpenoidal saponin of hederagenin named symphytoxide A has been isolated from the ethanolic extract of the roots of Symphytum officinale

  • A new triterpene glycoside from the roots of Symphytum officinale.
    Journal of natural products, 1993
    Co-Authors: Viqar Uddin Ahmad, Mushtaq Noorwala, Faryal Vali Mohammad, Bilge Sener
    Abstract:

    Chemical investigation of the EtOH-soluble portion of Symphytum officinale roots has resulted in the isolation of a new pentacyclic triterpene glycoside of oleanolic acid. Its structure was elucidated by spectroscopic studies, including 2D nmr, and chemical evidences as 3-O-[beta-D-glucopyranosyl-(1-->4)-beta-D-glucopyranosyl-(1-->4)-alpha-L -arabinopyranosyl]-oleanolic acid [1].

  • A New Bidesmosidic Triterpenoidal Saponin from the Roots of Symphytum officinale.
    Planta medica, 1993
    Co-Authors: Viqar Uddin Ahmad, Mushtaq Noorwala, Faryal Vali Mohammad, Bilge Sener
    Abstract:

    A new triterpenoidal saponin having hederagenin as the aglycone was isolated from the roots of Symphytum OFFICINALE L. The structure of this saponin was elucidated by FAB-MS, (1)H-, (13)C-NMR, 2D-NMR analyses and chemical studies as 3- O-[beta- D-glucopyranosyl-(1-->4)-alpha- L-arabinopyranosyl]-hederagenin 28- O-[beta- D-glucopyranosyl-(1-->6)-beta- D-glucopyranosyl] ester.

Khalid Aftab - One of the best experts on this subject based on the ideXlab platform.

  • Phyto-Pharmacology of Saponins from Symphytum officinale L.
    Advances in experimental medicine and biology, 1996
    Co-Authors: Khalid Aftab, Mushtaq Noorwala, Faryal Vali Mohammad, Fehmeena Shaheen, V. U. Ahmad
    Abstract:

    Symphytum officinale L. (comfrey) is a plant of Euro-American origin which belongs to the family Boraginaceae 1. It is a part of the practice of naturopathic medicine in Europe and America and is reported to have multiple therapeutic uses2,3,4.5,6 which include antiseptic, analgesic, antiinflammatory and antiulcer properties. It is also considered useful in several skin complications such as chronic wounds, burns, sores, eczema and wrinkles7. Moreover, the roots of this plant are used in he treatment of colds, asthma, bronchitis, tuberculosis, and hemorrhoids8. Comfrey is also. used in kidney diseases, cancer, and anaemia9.

  • Symphytoxide A, a triterpenoid saponin from the roots of Symphytum officinale
    Phytochemistry, 1993
    Co-Authors: Viqar Uddin Ahmad, Mushtaq Noorwala, Faryal Vali Mohammad, Bilge Sener, Anwar-ul-hassan Gilan, Khalid Aftab
    Abstract:

    Abstract A new triterpenoidal saponin of hederagenin named symphytoxide A has been isolated from the ethanolic extract of the roots of Symphytum officinale

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